Review
... staphylococci consisting of the mec and ccr gene complexes. There are five main types of SCCmec: type I SCCmec, carrying class B mec and type 1 ccr; type II SCCmec, carrying class A mec and type 2 ccr; type III SCCmec, carrying class A mec and type 3 ccr; type IV SCCmec, carrying class B mec and typ ...
... staphylococci consisting of the mec and ccr gene complexes. There are five main types of SCCmec: type I SCCmec, carrying class B mec and type 1 ccr; type II SCCmec, carrying class A mec and type 2 ccr; type III SCCmec, carrying class A mec and type 3 ccr; type IV SCCmec, carrying class B mec and typ ...
Zimax
... susceptible organisms and thus interferes with microbial protein synthesis. Following oral administration in humans, Zimax® (Azithromycin) is rapidly absorbed and widely distributed throughout the body ; bioavailability is approximately 37%. The time taken to peak plasma levels is 2-3 hours. However ...
... susceptible organisms and thus interferes with microbial protein synthesis. Following oral administration in humans, Zimax® (Azithromycin) is rapidly absorbed and widely distributed throughout the body ; bioavailability is approximately 37%. The time taken to peak plasma levels is 2-3 hours. However ...
Full-Text PDF
... Citrobacter species, group B streptococci, enterococci, Staphylococcus aureus, S. epidermidis, Klebsiella pneumoniae and Enterobacter species [1]. Thus, its antibacterial spectrum is broad and is particularly effective against the main uropathogens, hence its use for the treatment of urinary tract i ...
... Citrobacter species, group B streptococci, enterococci, Staphylococcus aureus, S. epidermidis, Klebsiella pneumoniae and Enterobacter species [1]. Thus, its antibacterial spectrum is broad and is particularly effective against the main uropathogens, hence its use for the treatment of urinary tract i ...
DEVELOPMENT AND VALIDATION OF RP-UPLC METHOD FOR ESTIMATION OF OFLOXAXCIN
... symmetry Ofloxacin were obtained with a mobile phase comprising of Phosphate Buffer: Acetonitrile (85:15, v/v) and PH of 3.0 adjusted by Triethylamine and orthophosperic acid at a flow rate of 0.4 ml/min to get better reproducibility and repeatability. Quantification was achieved with PDA detection ...
... symmetry Ofloxacin were obtained with a mobile phase comprising of Phosphate Buffer: Acetonitrile (85:15, v/v) and PH of 3.0 adjusted by Triethylamine and orthophosperic acid at a flow rate of 0.4 ml/min to get better reproducibility and repeatability. Quantification was achieved with PDA detection ...
Modifying effects of boswellia carteri on clarithromycine action: In
... inhibition of Boswellia carteri ranged from 6mmfor Pseudomonas aeruginosa to 14mm for Klebsiella pneumonia the p value was insignificant p ˃0.05 but the combined mixture showed significant differences from either clarithromycine or boswellia carteri p ˂0.05. The MIC ranged from 8-32mg/ml,8-64mg/ml a ...
... inhibition of Boswellia carteri ranged from 6mmfor Pseudomonas aeruginosa to 14mm for Klebsiella pneumonia the p value was insignificant p ˃0.05 but the combined mixture showed significant differences from either clarithromycine or boswellia carteri p ˂0.05. The MIC ranged from 8-32mg/ml,8-64mg/ml a ...
Cleocin Pediatric
... concentration had reached equilibrium. Peak serum concentrations after this time would be about 2.46, 2.98 and 3.79 mcg/mL with doses of 8, 12 and 16 mg/kg/day, respectively. Serum levels have been uniform and predictable from person to person and dose to dose. Multiple-dose studies in neonates and ...
... concentration had reached equilibrium. Peak serum concentrations after this time would be about 2.46, 2.98 and 3.79 mcg/mL with doses of 8, 12 and 16 mg/kg/day, respectively. Serum levels have been uniform and predictable from person to person and dose to dose. Multiple-dose studies in neonates and ...
Macrolid es, Ketolid es, a nd Glyc ylc yclines : Azithromyc in,
... first-pass metabolism, which results in an absolute oral bioavailability of 57%.23 The bioavailability, rate, and extent of absorption of telithromycin are unaffected by food.24 The single-dose pharmacokinetics of erythromycin, clarithromycin, azithromycin, and telithromycin are summarized in Table ...
... first-pass metabolism, which results in an absolute oral bioavailability of 57%.23 The bioavailability, rate, and extent of absorption of telithromycin are unaffected by food.24 The single-dose pharmacokinetics of erythromycin, clarithromycin, azithromycin, and telithromycin are summarized in Table ...
HIGHLIGHTS OF PRESCRIBING INFORMATION -----------------DOSAGE FORMS AND STRENGTHS------
... Tetracyclines are excreted in human milk; however, the extent of absorption of doxycycline in the breastfed infant is not known. Doxycycline use during nursing should be avoided if possible. (8.3) ...
... Tetracyclines are excreted in human milk; however, the extent of absorption of doxycycline in the breastfed infant is not known. Doxycycline use during nursing should be avoided if possible. (8.3) ...
DOXYCYCLINE CAPSULES, USP
... agents, including doxycycline, and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile. C. difficile produces toxins A and B which contribute to the development of CDAD. Hypertoxin p ...
... agents, including doxycycline, and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile. C. difficile produces toxins A and B which contribute to the development of CDAD. Hypertoxin p ...
Metronidazole - American Academy of Veterinary Pharmacology
... gastrointestinal disease has had major clinical impact, the relationship of Helicobacter species or Helicobacter-like organisms to gastric disease in cats and dogs has not been established. When evidence of infection with these organisms is found in a patient, a clinician may make a decision to trea ...
... gastrointestinal disease has had major clinical impact, the relationship of Helicobacter species or Helicobacter-like organisms to gastric disease in cats and dogs has not been established. When evidence of infection with these organisms is found in a patient, a clinician may make a decision to trea ...
Augmentin SR 1000mg Tablets
... Indications AUGMENTIN SR 1000mg Tablets is indicated in adults (≥ 16 years) in the treatment of the bacterial infections listed below. Infections of the respiratory tract: Community-acquired pneumonia, acute exacerbations of chronic bronchitis and acute bacterial sinusitis usually caused by Streptoc ...
... Indications AUGMENTIN SR 1000mg Tablets is indicated in adults (≥ 16 years) in the treatment of the bacterial infections listed below. Infections of the respiratory tract: Community-acquired pneumonia, acute exacerbations of chronic bronchitis and acute bacterial sinusitis usually caused by Streptoc ...
CIPRODEX ® Suspension
... and occasionally fatal hypersensitivity (anaphylactic) reactions, some following the first dose, have been reported in patients receiving systemic quinolones. Serious acute hypersensitivity reactions may require immediate emergency treatment. ...
... and occasionally fatal hypersensitivity (anaphylactic) reactions, some following the first dose, have been reported in patients receiving systemic quinolones. Serious acute hypersensitivity reactions may require immediate emergency treatment. ...
Cephalosporins
... spread of antimicrobial resistance. 4. Fourth generation: Cefepime [SEF-eh-peem] is classified as a fourth generation cephalosporin and must be administered parenterally. Cefepime has a wide antibacterial spectrum, being active against streptococci and staphylococci (but only those that are methicil ...
... spread of antimicrobial resistance. 4. Fourth generation: Cefepime [SEF-eh-peem] is classified as a fourth generation cephalosporin and must be administered parenterally. Cefepime has a wide antibacterial spectrum, being active against streptococci and staphylococci (but only those that are methicil ...
The Penicillins - Available Courses
... Staph. aureus, & Ps. aeruginosa ii. Lower respiratory tract infections due to b-lactamase-producing strains of Klebsiella pneumoniae, S. aureus, H. influenzae, & Moraxella catarrhalis iii. Bone & joint infections due to b-lactamase-producing Staph. aureus. iv. UTIs (complicated & uncomplicated) due ...
... Staph. aureus, & Ps. aeruginosa ii. Lower respiratory tract infections due to b-lactamase-producing strains of Klebsiella pneumoniae, S. aureus, H. influenzae, & Moraxella catarrhalis iii. Bone & joint infections due to b-lactamase-producing Staph. aureus. iv. UTIs (complicated & uncomplicated) due ...
Full Prescribing Information
... discoloration of the teeth (yellow-gray-brown). This adverse reaction is more common during long-term use of the drugs but it has been observed following repeated short-term courses. Enamel hypoplasia has also been reported. Use Doryx MPC in pediatric patients 8 years of age or less only when the po ...
... discoloration of the teeth (yellow-gray-brown). This adverse reaction is more common during long-term use of the drugs but it has been observed following repeated short-term courses. Enamel hypoplasia has also been reported. Use Doryx MPC in pediatric patients 8 years of age or less only when the po ...
amikai
... pharmaceutical innovator, continuously generating innovative drugs and services and maximizing its corporate value. Sankyo and Daiichi Pharmaceutical have a broad range of major drug products on the Japanese market, including the antihypertensive Benicar® (olmesartan medoxomil) and the synthetic ant ...
... pharmaceutical innovator, continuously generating innovative drugs and services and maximizing its corporate value. Sankyo and Daiichi Pharmaceutical have a broad range of major drug products on the Japanese market, including the antihypertensive Benicar® (olmesartan medoxomil) and the synthetic ant ...
NOROXIN TABLETS (NORFLOXACIN)
... Central Nervous System Effects/Disorders: Convulsions have been reported in patients receiving norfloxacin. Convulsions, increased intracranial pressure (including pseudotumor cerebri), and toxic psychoses have been reported in patients receiving drugs in this class. Quinolones may also cause centra ...
... Central Nervous System Effects/Disorders: Convulsions have been reported in patients receiving norfloxacin. Convulsions, increased intracranial pressure (including pseudotumor cerebri), and toxic psychoses have been reported in patients receiving drugs in this class. Quinolones may also cause centra ...
new zealand data sheet
... Upper respiratory tract infections, Genito-urinary tract infections, skin and soft tissue infections For upper respiratory tract infections due to streptococci, pneumococci, non-penicillinaseproducing staphylococci and H. influenzae) or Genito-Urinary Tract Infections (due to Escherichia coli, Prote ...
... Upper respiratory tract infections, Genito-urinary tract infections, skin and soft tissue infections For upper respiratory tract infections due to streptococci, pneumococci, non-penicillinaseproducing staphylococci and H. influenzae) or Genito-Urinary Tract Infections (due to Escherichia coli, Prote ...
PDF - Santen Inc.
... is an important element in that strategy,” says Schalon Newton, EDM, Santen’s Vice President of Strategic Marketing & Business Development. “We are committed to expanding our current pipeline and identifying the next generation of compounds to develop and market. We also are actively pursuing new, e ...
... is an important element in that strategy,” says Schalon Newton, EDM, Santen’s Vice President of Strategic Marketing & Business Development. “We are committed to expanding our current pipeline and identifying the next generation of compounds to develop and market. We also are actively pursuing new, e ...
What is Cipro - Public Health
... unlikely, if it occurs at all. Therefore, there is no need to treat contacts of persons ill with anthrax, such as household contacts, friends, or coworkers, unless they also were also exposed to the same source of infection. Should I ask my doctor to write a prescription for Cipro in case it's neede ...
... unlikely, if it occurs at all. Therefore, there is no need to treat contacts of persons ill with anthrax, such as household contacts, friends, or coworkers, unless they also were also exposed to the same source of infection. Should I ask my doctor to write a prescription for Cipro in case it's neede ...
Gentamicin
... • Polymyxins are active mainly against gramnegative bacilli, particulary pseudomonas and coliform organisms. Mechanism of action of polymyxins Polymyxins act by attaching to the cell membranes of bacteria and other membranes rich in phosphatidylethanolamin (磷脂酰乙醇胺) and disrupting the osmotic propert ...
... • Polymyxins are active mainly against gramnegative bacilli, particulary pseudomonas and coliform organisms. Mechanism of action of polymyxins Polymyxins act by attaching to the cell membranes of bacteria and other membranes rich in phosphatidylethanolamin (磷脂酰乙醇胺) and disrupting the osmotic propert ...
Gentamicin
... • Polymyxins are active mainly against gramnegative bacilli, particulary pseudomonas and coliform organisms. Mechanism of action of polymyxins Polymyxins act by attaching to the cell membranes of bacteria and other membranes rich in phosphatidylethanolamin (磷脂酰乙醇胺) and disrupting the osmotic propert ...
... • Polymyxins are active mainly against gramnegative bacilli, particulary pseudomonas and coliform organisms. Mechanism of action of polymyxins Polymyxins act by attaching to the cell membranes of bacteria and other membranes rich in phosphatidylethanolamin (磷脂酰乙醇胺) and disrupting the osmotic propert ...
Document
... Flurorquinolones (FQs) are a class of important synthetic antibiotics, which are active against both Gram (+) and Gram (-) bacteria through inhibition of their DNA gyrase [1]. Their excellent pharmacokinetic profile, good tissular penetration and wide scope of activity have made these drugs very use ...
... Flurorquinolones (FQs) are a class of important synthetic antibiotics, which are active against both Gram (+) and Gram (-) bacteria through inhibition of their DNA gyrase [1]. Their excellent pharmacokinetic profile, good tissular penetration and wide scope of activity have made these drugs very use ...
Disadvantages of penicillin G
... Broad spectrum penicillins ( cont ) B ) Extended- spectrum : Ticarcillin-clavulanic acid, piperacillin,piperacillin-tazobactam ( Tazocin ) Uses Pseud. aeruginosa. For pseud.septicemia, they should be given together with an aminoglycoside ( eg. Gentamicin ). Disadvantages Ticarcillin and piperacilli ...
... Broad spectrum penicillins ( cont ) B ) Extended- spectrum : Ticarcillin-clavulanic acid, piperacillin,piperacillin-tazobactam ( Tazocin ) Uses Pseud. aeruginosa. For pseud.septicemia, they should be given together with an aminoglycoside ( eg. Gentamicin ). Disadvantages Ticarcillin and piperacilli ...
Levofloxacin
Levofloxacin (trade names Levaquin (US), Tavanic (EU), and others) is a broad-spectrum antibiotic of the fluoroquinolone drug class, and the levo isomer of its predecessor ofloxacin. Its spectrum of activity includes most strains of bacterial pathogens responsible for respiratory, urinary tract, gastrointestinal, and abdominal infections, including Gram negative (Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Legionella pneumophila, Moraxella catarrhalis, Proteus mirabilis, and Pseudomonas aeruginosa), Gram positive (methicillin-sensitive but not methicillin-resistant Staphylococcus aureus, Streptococcus pneumoniae, Staphylococcus epidermidis, Enterococcus faecalis, and Streptococcus pyogenes), and atypical bacterial pathogens (Chlamydophila pneumoniae and Mycoplasma pneumoniae). Compared to earlier antibiotics of the fluoroquinoline class such as ciprofloxacin, levofloxacin exhibits greater activity towards Gram-positive bacteria but lesser activity toward Gram-negative bacteria, especially Pseudomonas aeruginosa. Levofloxacin and later generation fluoroquinolones are collectively referred to as ""respiratory quinolones"" to distinguish them from earlier fluoroquinolones which exhibited modest activity toward the important respiratory pathogen Streptococcus pneumoniae.Levofloxacin and other fluoroquinolones are valued for their broad spectrum of activity, excellent tissue penetration, and for their availability in both oral and intravenous formulations. Levofloxacin is used alone or in combination with other antibacterial drugs to treat certain bacterial infections including pneumonia, urinary tract infections, and abdominal infections.Levofloxacin and other fluoroquinolones are generally well tolerated, but in rare instances have produced serious adverse reactions such as spontaneous tendon ruptures and irreversible peripheral neuropathy. Tendon damage may manifest months after therapy had been completed. Levofloxacin may cause worsening of myasthenia gravis symptoms, including muscle weakness and breathing problems.