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GWASdb v2: an update database for human
GWASdb v2: an update database for human

... population, from published GWASs. We performed deep and high-quality curation for moderate effect TASs according to related materials of each publication. GWASdb v2 also introduces a batch of new features including new ontology mapping, multi-level annotation, causal gene prediction and an updated i ...
Scientists Figure Out How The Immune System And Brain Interact To
Scientists Figure Out How The Immune System And Brain Interact To

... Scientists Figure Out How The Immune System And Brain Interact To Control Disease 23 Jul 2008 In a major step in understanding how the nervous system and the immune system interact, scientists at The Feinstein Institute for Medical Research have identified a new anatomical path through which the bra ...
Creation of a Computational Pipeline to Extract Genes from
Creation of a Computational Pipeline to Extract Genes from

... understand which SNP variants underlie a predisposition for the development of Type 2 diabetes and obesity in order to improve future prevention and treatment. Genetic mapping is an effective tool for identifying quantitative trait loci (QTL) since genetic loci that contribute to specific traits can ...
The human brain has on average 100 billion neurons, to each
The human brain has on average 100 billion neurons, to each

... scientific tools, more has become understood of that which is the source of our cognitive and physical behaviour. Elie Matar reports. A team of scientists at the University of Sydney have taken a step back to focus on an observation made by Richard Caton in 1875 and since has become a widely known f ...
Psychosurgery: past, present, and future
Psychosurgery: past, present, and future

... lesion, resulting in fewer side-effects and less mortality. Furthermore, developments in the neurobiology of emotion provided more refined targets for neurosurgical intervention. The pioneering work of Papez [71] and its further evaluation by MacLean [53] led to the elucidation of important structur ...
SNP - Nature
SNP - Nature

... C2775A: Amount of 5-HT in SY5Y cells expressing the TPH2-41Y allele 36% lower than cells expressing the TPH2-41S allele 4. AA haplotype had higher levels of TPH2 mRNA and protein, and higher 5-HT production than the wildtype CG genotype in PC12 cells. Both C74A and G223A predicted to change mRNA sec ...
fMRI of speech and language
fMRI of speech and language

... End result: neurons fire => MRI signal goes up ...
Limbic system – Emotional Experience
Limbic system – Emotional Experience

... When we lose a battle, a match, or a job, the hippocampus is stimulated making sure we would remember the loss forever. The center of our emotions, the amygdala, fuses this sense of memory into a profound notion of misery. This all creates a powerful reminder of failure to put us off making the same ...
Nervous and Endocrine System
Nervous and Endocrine System

... • At the end of class you should be able to: – Understand the various parts of the nervous system and explain their functions. – Understand how the hormones of the endocrine system differ from the nervous system? ...
Effects of Exercise Following Lateral Fluid Percussion Brain Injury in
Effects of Exercise Following Lateral Fluid Percussion Brain Injury in

... Restorative Neurology and Neuroscience 12 (1998) 41-46 ...
Full Text PDF - Jaypee Journals
Full Text PDF - Jaypee Journals

... Prenatal Development of the Human Central Nervous System, Normal and Abnormal ...
TINS04
TINS04

... This plurality of symptoms has led to two broad approaches to dyslexia. One has been to concentrate on one particular cognitive symptom thought to reflect the most direct causal explanation: for instance, in the phonological theory of dyslexia[5] (Figure 1A), a specific deficit in the representation ...
The adult human testis produces millions of sperm
The adult human testis produces millions of sperm

... TIMP-2 to act as a key effector of the pro-neurogenic response to an inducing stimulus, such as Marimastat. We also addressed the molecular mechanisms involved in the regulation of NP properties. We focused our attention on the RE1-silencing transcription factor (REST), a master regulator of neurona ...
mechanisms of neurotransmitter receptor biogenesis and trafficking
mechanisms of neurotransmitter receptor biogenesis and trafficking

... neurotransmitter receptor formation and trafficking. Here, she discusses her interests, her research and the promise of its therapeutic application understand brain function. Computers will be the key to storing, processing and integrating vast amounts of information, as well as to modelling and map ...
1. Identify the functions of the nervous system and relate nervous
1. Identify the functions of the nervous system and relate nervous

... Label the parts of the generalized neuron on this page. Indicate the function of each part of the neuron in your notebook. ...
Newswire Newswire - Rockefeller University
Newswire Newswire - Rockefeller University

... In a recent study, Bargmann and her colleagues showed that worms in their larval stage can learn what harmful bacterial strains smell like, and form aversions to those smells that last into adulthood. Among other things, Bargmann is interested in how genes and neural pathways allow for such flexibil ...
Central adrenergic receptor changes in the
Central adrenergic receptor changes in the

... A n additional possibility that merits consideration is that the adrenergic receptor profiles in the mature animal determined in the present study might reflect an 'adaptive' or 'recovered' state of the postsynaptic components on the target cells after an initial and perhaps transient period of rece ...
Chapter 7 Body Systems
Chapter 7 Body Systems

...  Both sides communicate with each other to accomplish complex functions  Left hemisphere is responsible for:  Language functions  Dominating control of certain hand movements  Right hemisphere is responsible for: ...
Possible Links among Mirror Neurons and Genes
Possible Links among Mirror Neurons and Genes

... Berwin, B., Floor, E. and Martin, T.F. (1998). CAPS (mammalian UNC-31) protein localizes to membranes involved in dense-core vesicle exocytosis. Neuron 21, 137–145. Bibel, M. and Barde, Y.A. (2000). Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system. Genes & D ...
CN510: Principles and Methods of Cognitive and
CN510: Principles and Methods of Cognitive and

... Most neuroscientists agree on the following: – The neuron is the basic signaling unit in the brain – Different parts of the brain have different functional roles (e.g. auditory cortex, visual cortex, motor cortex, etc.) – The different brain regions project to each other in a fairly precise fashion ...
CHAPTER2studynotes
CHAPTER2studynotes

... brainstem and the cerebellum extends from the rear. The limbic system includes the amygdala, the hippocampus, and the hypothalamus. The cerebral cortex, representing the highest level of brain development, is responsible for our most complex functions. Each hemisphere of the cerebral cortex has four ...
BIOPSYCHOLOGY 8e John PJ Pinel
BIOPSYCHOLOGY 8e John PJ Pinel

... •  Extra chromosome 21 created during ovulation •  Characteristic facial features, cognitive impairments, other health problems (premature aging, increased risk of Alzheimer’s) Copyright © Pearson Education 2011 ...
Module 3 - Victor Valley College
Module 3 - Victor Valley College

... • To date, about 150 Parkinson’s patients have been treated with fetal tissue transplants – about 30 to 60% showed substantial improvement, but none have been completely cured – patients under 60 showed most improvement, while those over 60 reported little or no improvement in symptoms ...
Scientific American
Scientific American

... loss of all functions of the cortex and of the brainstem. It is important to mention that there is a well documented report of a patient with constant registration of the EEG during cerebral surgery for an gigantic cerebral aneurysm at the base of the brain, operated with a body temperature between ...
Variation in copy number and gene expression in the laboratory
Variation in copy number and gene expression in the laboratory

... to at least one other genomic region) act as nurseries of CNV by promoting NAHR has been supported by the enrichment of segmental duplications within and around CNVRs20,25. By permutation testing (see Methods), we found that there is significantly more segmental duplication sequence within and direc ...
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