- Wiley Online Library
... F I G U R E 3 Initiation and production of vocal motor patterns in X. laevis. (a) The ex vivo brain (Figure 1a) now viewed from the side and illustrating subdivisions (hindbrain, midbrain, and forebrain) that include neural circuits participating in initiation of vocal patterns. In an adult male bra ...
... F I G U R E 3 Initiation and production of vocal motor patterns in X. laevis. (a) The ex vivo brain (Figure 1a) now viewed from the side and illustrating subdivisions (hindbrain, midbrain, and forebrain) that include neural circuits participating in initiation of vocal patterns. In an adult male bra ...
Probing forebrain to hindbrain circuit functions in Xenopus
... F I G U R E 3 Initiation and production of vocal motor patterns in X. laevis. (a) The ex vivo brain (Figure 1a) now viewed from the side and illustrating subdivisions (hindbrain, midbrain, and forebrain) that include neural circuits participating in initiation of vocal patterns. In an adult male bra ...
... F I G U R E 3 Initiation and production of vocal motor patterns in X. laevis. (a) The ex vivo brain (Figure 1a) now viewed from the side and illustrating subdivisions (hindbrain, midbrain, and forebrain) that include neural circuits participating in initiation of vocal patterns. In an adult male bra ...
Probing forebrain to hindbrain circuit functions in
... autonomic responses. The close links between autonomic functions that are essential for life and vocal expression have been a major in vivo experimental challenge. Xenopus provides an opportunity to address this challenge using an ex vivo preparation: an isolated brain that generates vocal and breat ...
... autonomic responses. The close links between autonomic functions that are essential for life and vocal expression have been a major in vivo experimental challenge. Xenopus provides an opportunity to address this challenge using an ex vivo preparation: an isolated brain that generates vocal and breat ...
Basal Ganglia and Associated Pathways
... is a source of input into the basal ganglia (striatum) and serves as a modulatory pathway of the direct and indirect basal ganglia pathways. Inputs into the pars compacta itself remain unclear, but at least some are from the striatum (striosome). Clinically, this pathway is most important for its ro ...
... is a source of input into the basal ganglia (striatum) and serves as a modulatory pathway of the direct and indirect basal ganglia pathways. Inputs into the pars compacta itself remain unclear, but at least some are from the striatum (striosome). Clinically, this pathway is most important for its ro ...
322 Neuroscience I - Jordan University of Science and Technology
... seminars topics, and self-directed learning methods. The overall goal of the Neuroscience I course is to provide basic knowledge and understanding of the structure, function of the nervous system, biochemical basis of human behavior, as well as the pathological basis of neurological and mental disor ...
... seminars topics, and self-directed learning methods. The overall goal of the Neuroscience I course is to provide basic knowledge and understanding of the structure, function of the nervous system, biochemical basis of human behavior, as well as the pathological basis of neurological and mental disor ...
Deep Neural Networks for Anatomical Brain Segmentation
... brain (cortical and sub-cortical areas) into a large number N of anatomical regions, where N is defined by the segmentation protocol (typically around 100). Knowledge of the segmentation protocol is implicitly given through a set of manually labelled 3D brain MRIs. An atlas consists of an MR image a ...
... brain (cortical and sub-cortical areas) into a large number N of anatomical regions, where N is defined by the segmentation protocol (typically around 100). Knowledge of the segmentation protocol is implicitly given through a set of manually labelled 3D brain MRIs. An atlas consists of an MR image a ...
Diversity of reporter expression patterns in transgenic mouse lines
... thus rendered amenable to electrophysiology and/or optogenetic or chemical/ genetic manipulations (eg, designer receptors exclusively activated by designer drugs, DREADD). Collectively, these approaches have confirmed and extended information about the localization, nature and connectivity of CRH-ex ...
... thus rendered amenable to electrophysiology and/or optogenetic or chemical/ genetic manipulations (eg, designer receptors exclusively activated by designer drugs, DREADD). Collectively, these approaches have confirmed and extended information about the localization, nature and connectivity of CRH-ex ...
Lecture VIII. Spinal Cord
... weren’t inhibited to extend the other (contralateral) leg to stand on. ...
... weren’t inhibited to extend the other (contralateral) leg to stand on. ...
Presentation - Neuropathology
... ▪Most common cause of dementia, characterized pathologically by the presence of senile plaques and neurofibrillary tangles (NFT) Incidence and Prevalence ▪Incidence increases with age: between 70 and 80 years—1 to 2 cases per 100 individuals per year; >80 years—2 to 8 cases per 100 individuals per y ...
... ▪Most common cause of dementia, characterized pathologically by the presence of senile plaques and neurofibrillary tangles (NFT) Incidence and Prevalence ▪Incidence increases with age: between 70 and 80 years—1 to 2 cases per 100 individuals per year; >80 years—2 to 8 cases per 100 individuals per y ...
Laboratory Guide - Sites@Duke
... organization of the human brain, which is the foundation for understanding brain function and the dysfunctions that disorder human behavior. Indeed, the neuroanatomical detail required for competent research in the cognitive sciences, including the emerging field of Neurohumanities, forms a very lim ...
... organization of the human brain, which is the foundation for understanding brain function and the dysfunctions that disorder human behavior. Indeed, the neuroanatomical detail required for competent research in the cognitive sciences, including the emerging field of Neurohumanities, forms a very lim ...
The assessment of hemispheric lateralization in functional MRI
... functional magnetic resonance imaging (fMRI), functional transcranial Doppler sonography (Deppe et al., 2004), magnetoencephalography (Hirata et al., 2004) and infrared spectroscopy (Watson et al., 2004), it became possible to non-invasively investigate the lateralization of cognitive brain function ...
... functional magnetic resonance imaging (fMRI), functional transcranial Doppler sonography (Deppe et al., 2004), magnetoencephalography (Hirata et al., 2004) and infrared spectroscopy (Watson et al., 2004), it became possible to non-invasively investigate the lateralization of cognitive brain function ...
Lecture VIII. Spinal Cord
... weren’t inhibited to extend the other (contralateral) leg to stand on. ...
... weren’t inhibited to extend the other (contralateral) leg to stand on. ...
A Split-LexA-based Concatenate Expression System for
... heterodimerize and drive the expression of the transgene downstream of the LexAop promoter. (D-D’’’) The Split LexA system efficiently drives reporter expression in vivo. An ortLexADBD hemidriver was used in combination with the pan-neuronal hemidriver elavVP16AD to drive the expression of a membra ...
... heterodimerize and drive the expression of the transgene downstream of the LexAop promoter. (D-D’’’) The Split LexA system efficiently drives reporter expression in vivo. An ortLexADBD hemidriver was used in combination with the pan-neuronal hemidriver elavVP16AD to drive the expression of a membra ...
and “Wanting” Linked to Reward Deficiency
... NEUROBIOLOGY OF REWARD DEFICIENCY SYNDROME The term, Reward Deficiency Syndrome (RDS) was first coined by Blum et al. [2,3] and refers to an insufficiency of usual feelings of satisfaction. RDS results from a dysfunction in the “brain reward cascade,” a complex interaction among neurotransmitters(pr ...
... NEUROBIOLOGY OF REWARD DEFICIENCY SYNDROME The term, Reward Deficiency Syndrome (RDS) was first coined by Blum et al. [2,3] and refers to an insufficiency of usual feelings of satisfaction. RDS results from a dysfunction in the “brain reward cascade,” a complex interaction among neurotransmitters(pr ...
Experimental design and statistical analysis of SNP data obtained in
... There are two main groups of experimental designs for genetic associations studies. These are case-control designs and family-based designs. Here we have concentrated on case-control designs, where we have cases with disease and controls, which are unrelated to the cases, without disease. There are ...
... There are two main groups of experimental designs for genetic associations studies. These are case-control designs and family-based designs. Here we have concentrated on case-control designs, where we have cases with disease and controls, which are unrelated to the cases, without disease. There are ...
Natural Variation of ebony Gene Controlling Thoracic
... and Gr93f showed that the critical region lies between markers r-l and tin (Figure 2B). Note that one line in Figure 2A that showed nonpigmented phenotype but had TW1 genotype at Gr93f is represented as MT10-64 in Figure 2B. This line actually had Mel6 genotype at most of the marker positions betwee ...
... and Gr93f showed that the critical region lies between markers r-l and tin (Figure 2B). Note that one line in Figure 2A that showed nonpigmented phenotype but had TW1 genotype at Gr93f is represented as MT10-64 in Figure 2B. This line actually had Mel6 genotype at most of the marker positions betwee ...
R eelin is expressed in the accessory olfactory system, but is not a
... projections are indistinguishable from the wild-type animals (Fig. 2A,C,E,G versus B,D,F,H). The pathfinding, axonal fasciculation, and axonal convergence of the VN12 neurons appear to be normal in the reeler mice. Reln mRNA is expressed at varying levels in the mouse olfactory system. Our findings, ...
... projections are indistinguishable from the wild-type animals (Fig. 2A,C,E,G versus B,D,F,H). The pathfinding, axonal fasciculation, and axonal convergence of the VN12 neurons appear to be normal in the reeler mice. Reln mRNA is expressed at varying levels in the mouse olfactory system. Our findings, ...
Somatosensory cortex functional connectivity
... connectivity in a region driven by a functionally appropriate task is indeed characteristic of ASD, as we speculated, it would suggest that we should be able to observe reduced local functional connectivity in other cortical areas and using different experimental paradigms. To address these open que ...
... connectivity in a region driven by a functionally appropriate task is indeed characteristic of ASD, as we speculated, it would suggest that we should be able to observe reduced local functional connectivity in other cortical areas and using different experimental paradigms. To address these open que ...
Size Variation in Drosophila melanogaster
... large sample sizes if alleles have low population frequencies or modest effects. As a complementary approach, we propose that population-based resequencing of experimentally evolved populations allows for considerable power to map functional variation. Here, we use this technique to investigate the ...
... large sample sizes if alleles have low population frequencies or modest effects. As a complementary approach, we propose that population-based resequencing of experimentally evolved populations allows for considerable power to map functional variation. Here, we use this technique to investigate the ...
Brain-Derived Neurotrophic Factor Reduces Amyloidogenic
... Sorting protein-related receptor with A-type repeats (SORLA) is a major risk factor in cellular processes leading to Alzheimer’s disease (AD). It acts as sorting receptor for the amyloid precursor protein (APP) that regulates intracellular trafficking and processing into amyloidogenic- peptides (A ...
... Sorting protein-related receptor with A-type repeats (SORLA) is a major risk factor in cellular processes leading to Alzheimer’s disease (AD). It acts as sorting receptor for the amyloid precursor protein (APP) that regulates intracellular trafficking and processing into amyloidogenic- peptides (A ...
Identification of causal genes for complex traits
... Motivation: Although genome-wide association studies (GWAS) have identified thousands of variants associated with common diseases and complex traits, only a handful of these variants are validated to be causal. We consider ‘causal variants’ as variants which are responsible for the association signa ...
... Motivation: Although genome-wide association studies (GWAS) have identified thousands of variants associated with common diseases and complex traits, only a handful of these variants are validated to be causal. We consider ‘causal variants’ as variants which are responsible for the association signa ...
The Molecular and Neuroanatomical Basis for Estrogen Effects in
... which estrogens can interact with signaling pathways involving cell surface receptors and thereby participate in cellular events also regulated by growth factors and neurotransmitters. These processes (summarized in Table 1 and Fig. 1) are often interrelated at the level of intracellular signaling, ...
... which estrogens can interact with signaling pathways involving cell surface receptors and thereby participate in cellular events also regulated by growth factors and neurotransmitters. These processes (summarized in Table 1 and Fig. 1) are often interrelated at the level of intracellular signaling, ...
Neurological Consequences
... about working at NA ADAC. After a few minutes of thought, the answer put a grin on my face. I responded, “I most love training addiction professionals about medication-assisted treatment and recovery. Picture a day where I am presenting an all-day training in Anytown, USA that required planes, trai ...
... about working at NA ADAC. After a few minutes of thought, the answer put a grin on my face. I responded, “I most love training addiction professionals about medication-assisted treatment and recovery. Picture a day where I am presenting an all-day training in Anytown, USA that required planes, trai ...
View/Open - University of Pretoria
... Our method, implemented in the R package bugwas, revealed strong signals of association between fusidic acid resistance and lineages including PC-6 and PC-9 (P = 10−70), comparable in significance to the low-frequency variants at fusA (Fig. 1c and Supplementary Fig. 6). We next reassessed locus-spec ...
... Our method, implemented in the R package bugwas, revealed strong signals of association between fusidic acid resistance and lineages including PC-6 and PC-9 (P = 10−70), comparable in significance to the low-frequency variants at fusA (Fig. 1c and Supplementary Fig. 6). We next reassessed locus-spec ...
Differences between psychopathy and other personality disorders
... to controls (Marsh 2008b; Jones 2009). Also, compared with controls, adults with psychopathy show an atypical pattern of greater visual cortical (fusiform gyrus) activity in response to neutral rather than fearful expressions, and also reduced fusiform gyrus activity in response to fearful expressio ...
... to controls (Marsh 2008b; Jones 2009). Also, compared with controls, adults with psychopathy show an atypical pattern of greater visual cortical (fusiform gyrus) activity in response to neutral rather than fearful expressions, and also reduced fusiform gyrus activity in response to fearful expressio ...