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TOPIC: Cells AIM: What are the parts of a cell?
TOPIC: Cells AIM: What are the parts of a cell?

... An organism made up of only one cell is called (1)multicellular (2) prokaryotic (3) unicellular (4) eukaryotic ...
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a - Rainbow Resource

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Cell Analogy Project
Cell Analogy Project

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Surviving apoptosis: life–death signaling in single cells

... proteins exhibit both functions simultaneously (e.g., through interactions within different protein complexes), or have a survival role only when death is inhibited. Some of these proteins (e.g., caspases) belong to multiple signaling pathways (Box 1), while others, such as the TNF family of death l ...
a morphogenetic role for the TNF signalling pathway
a morphogenetic role for the TNF signalling pathway

... Fig. 1. Components and outcomes of selected TNF-superfamily signalling pathways. (Left) The pathway triggered by TNF is well characterized and the molecules that transmit the signal to the biological outcomes are largely known. In response to binding of TNF, the intracellular part of the TNFR recrui ...
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Apoptosis



Apoptosis (/ˌæpəˈtoʊsɪs/; from Ancient Greek ἀπό apo, ""by, from, of, since, than"" and πτῶσις ptōsis, ""fall"") is the process of programmed cell death that may occur in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, chromosomal DNA fragmentation, and global mRNA decay.In contrast to necrosis, which is a form of traumatic cell death that results from acute cellular injury, apoptosis is a highly regulated and controlled process that confers advantages during an organism's lifecycle. For example, the separation of fingers and toes in a developing human embryo occurs because cells between the digits undergo apoptosis. Unlike necrosis, apoptosis produces cell fragments called apoptotic bodies that phagocytic cells are able to engulf and quickly remove before the contents of the cell can spill out onto surrounding cells and cause damage.Between 50 and 70 billion cells die each day due to apoptosis in the average human adult. For an average child between the ages of 8 and 14, approximately 20 billion to 30 billion cells die a day.Research in and around apoptosis has increased substantially since the early 1990s. In addition to its importance as a biological phenomenon, defective apoptotic processes have been implicated in a wide variety of diseases. Excessive apoptosis causes atrophy, whereas an insufficient amount results in uncontrolled cell proliferation, such as cancer.Some factors like Fas receptor, caspases (C-cysteine rich, asp- aspartic acid moiety containing, ase – proteases) etc. promote apoptosis, while members of Bcl-2 inhibit apoptosis.
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