IMMUNOREACTIONS INVOLVING PLATELETS. VI. REACTIONS OF
... Mother K's serum alone, was consistently but weakly positive with PlA(1,1) platelets, but negative with PlA(-,-) platelets. The amount of antiglobulin consumed by PlA(1,1) platelets exposed to Mother K's serum was similar to the amount consumed by the same number of PlA(1,1) platelets saturated with ...
... Mother K's serum alone, was consistently but weakly positive with PlA(1,1) platelets, but negative with PlA(-,-) platelets. The amount of antiglobulin consumed by PlA(1,1) platelets exposed to Mother K's serum was similar to the amount consumed by the same number of PlA(1,1) platelets saturated with ...
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... are intended for parenteral administration. This not only results in poor patient compliance but is also unable to elicit mucosal immunity, eliciting only a systemic antibody response, which is often insufficient to tackle pathogens that employ mucosal surfaces for ingress into the host or which res ...
... are intended for parenteral administration. This not only results in poor patient compliance but is also unable to elicit mucosal immunity, eliciting only a systemic antibody response, which is often insufficient to tackle pathogens that employ mucosal surfaces for ingress into the host or which res ...
Antibody phage-displayed libraries derived from chicken
... A process known as hybridoma technology has been widely used to generate mAbs since its introduction by Köhler and Milstein in 1975. This method is laborious, often inefficient and is usually used to generate murine antibodies. This means that when used therapeutically they are likely to be immunoge ...
... A process known as hybridoma technology has been widely used to generate mAbs since its introduction by Köhler and Milstein in 1975. This method is laborious, often inefficient and is usually used to generate murine antibodies. This means that when used therapeutically they are likely to be immunoge ...
Monoclonal Versus Polyclonal Antibodies: Distinguishing
... useful research tool in that it can serve as the basis for identifying related antigens; however, this method can be confounding when recognizing epitopes on unrelated antigens. The specificity of an antibody refers to its ability to recognize a specific epitope in the presence of other epitopes. An ...
... useful research tool in that it can serve as the basis for identifying related antigens; however, this method can be confounding when recognizing epitopes on unrelated antigens. The specificity of an antibody refers to its ability to recognize a specific epitope in the presence of other epitopes. An ...
RTF - Austin Community College
... b. Each time blood is drawn the nurse notates it on the chart, once the amount becomes significant the baby must be transfused. 4. Supplying blood banks should be capable of providing components tailored to satisfy the specific requirements of these tiny recipients whose small blood volumes and impa ...
... b. Each time blood is drawn the nurse notates it on the chart, once the amount becomes significant the baby must be transfused. 4. Supplying blood banks should be capable of providing components tailored to satisfy the specific requirements of these tiny recipients whose small blood volumes and impa ...
Cloning and expression analysis of three novel CC chemokine
... other CC chemokines shows that four cysteine residues are conserved. A phylogenetic tree showed ...
... other CC chemokines shows that four cysteine residues are conserved. A phylogenetic tree showed ...
Antibody response to DBY minor histocompatibility antigen is
... specificity controls. All patients and donors were previously screened for antibody to HIVp24 and were known to be negative. Western blotting experiments shown in Figure 1 were used to detect the presence of antibodies specific for these proteins. Coomassie stains of E coli–derived affinity-purified ...
... specificity controls. All patients and donors were previously screened for antibody to HIVp24 and were known to be negative. Western blotting experiments shown in Figure 1 were used to detect the presence of antibodies specific for these proteins. Coomassie stains of E coli–derived affinity-purified ...
Population dynamics of immune repertoires
... which we describe now. The general idea behind this class of models is that one important signal for which lymphocytes compete comes from antigens. Strong antigenic recognition by mature lymphocytes generally triggers clonal expansion into effector and memory cells. These strong signals are usually ...
... which we describe now. The general idea behind this class of models is that one important signal for which lymphocytes compete comes from antigens. Strong antigenic recognition by mature lymphocytes generally triggers clonal expansion into effector and memory cells. These strong signals are usually ...
Analyzing the antibody against H-Y antigen in hematopoietic cell
... The second procedure, the allogeneic transplant, engrafts stem cells from a donor who is genetically matched to the patient for genes in the human leukocyte antigen (HLA) super-locus. Matching is necessary because the HLA genes govern the interactions between the immune system and all other cells. ...
... The second procedure, the allogeneic transplant, engrafts stem cells from a donor who is genetically matched to the patient for genes in the human leukocyte antigen (HLA) super-locus. Matching is necessary because the HLA genes govern the interactions between the immune system and all other cells. ...
1986 Hohenboken et al.: Inheritance of active and passive humoral
... levelstand, in oneexperiment, high levelsas well) wereassociated with lowerneonatal survival. In cattle, there was little evidence that either active immune response or level of complement protein C3 was heritable; but in ewes, the antibody titre to a challenge antigen was moderately to highly herit ...
... levelstand, in oneexperiment, high levelsas well) wereassociated with lowerneonatal survival. In cattle, there was little evidence that either active immune response or level of complement protein C3 was heritable; but in ewes, the antibody titre to a challenge antigen was moderately to highly herit ...
Immunomodulation of pathogen-host interactions
... plasma using affinity technology. We have tested the efficacy of removal by spiking the anticoagulated blood and plasma with known amount of TLR agonist and measured their capture under dynamic conditions. We have tested several affinity resins, and the result of the most efficient one is presented ...
... plasma using affinity technology. We have tested the efficacy of removal by spiking the anticoagulated blood and plasma with known amount of TLR agonist and measured their capture under dynamic conditions. We have tested several affinity resins, and the result of the most efficient one is presented ...
Proceedings Template - WORD
... increasing the same parameter ratios. Robustness to Noise: In addition to favoring a regulatory response, effective GDP decision-making must be robust against noise and short time-scale efforts of the pathogen to circumvent the GDP detection mechanism. This means that the immune system must have the ...
... increasing the same parameter ratios. Robustness to Noise: In addition to favoring a regulatory response, effective GDP decision-making must be robust against noise and short time-scale efforts of the pathogen to circumvent the GDP detection mechanism. This means that the immune system must have the ...
Immunological aspects of liver disease
... Williams of a hypothesis which used the concepts of T-cell mediated help and suppression, to explain how viral induced liver specific autoimmunity could be responsible for the immunopathogenesis of chronic active hepatitis, and how HLA B8 might be tied to this process9; the setting up, by Ian McFarl ...
... Williams of a hypothesis which used the concepts of T-cell mediated help and suppression, to explain how viral induced liver specific autoimmunity could be responsible for the immunopathogenesis of chronic active hepatitis, and how HLA B8 might be tied to this process9; the setting up, by Ian McFarl ...
keyhole limpet haemocyanin, KLH
... elicit antibody responses, both to the coupled peptide and to the carrier molecule. A common carrier protein of high molecular weight and antigenicity is keyhole limpet haemocyanin (KLH). Carrier-specific antibodies often correspond to a significant fraction of the total antibody pool (10% or more) ...
... elicit antibody responses, both to the coupled peptide and to the carrier molecule. A common carrier protein of high molecular weight and antigenicity is keyhole limpet haemocyanin (KLH). Carrier-specific antibodies often correspond to a significant fraction of the total antibody pool (10% or more) ...
Modulation of AAV vector dosing and avoidance of capsid immune
... re-dosing in a large animal model of liver gene transfer; • The use of SVP[Rapa] in conjunction with AAV gene transfer appears to be a safe and effective strategy for the modulation of vector immunogenicity. ...
... re-dosing in a large animal model of liver gene transfer; • The use of SVP[Rapa] in conjunction with AAV gene transfer appears to be a safe and effective strategy for the modulation of vector immunogenicity. ...
Major Histocompatibility Complex (MHC)
... • Crossing over frequency (0.5%) between MHC genes is very less. • Thus, MHC alleles present on one chromosome tends to remain as such and inherited as set. • This set of MHC alleles is generally termed as “Haplotype”. • Thus, a person have two haplotypes transferred from mother and father. • MHC Al ...
... • Crossing over frequency (0.5%) between MHC genes is very less. • Thus, MHC alleles present on one chromosome tends to remain as such and inherited as set. • This set of MHC alleles is generally termed as “Haplotype”. • Thus, a person have two haplotypes transferred from mother and father. • MHC Al ...
Antibody
... kinds of antibodies, which are grouped into different isotypes based on which heavy chain they possess. Five different antibody isotypes are known in mammals, which perform different roles, and help direct the appropriate immune response for each different type of foreign object they encounter.[7] T ...
... kinds of antibodies, which are grouped into different isotypes based on which heavy chain they possess. Five different antibody isotypes are known in mammals, which perform different roles, and help direct the appropriate immune response for each different type of foreign object they encounter.[7] T ...
Detection of antibodies to common antigens of pathogenic and
... to N . lactamica, were also demonstrated. Antibody against all antigens was more prevalent in bactericidal than in non-bactericidal sera, although these differences were statistically not significant. Differences in antibody prevalence between carriers of Neisseria spp. and non-carriers of these org ...
... to N . lactamica, were also demonstrated. Antibody against all antigens was more prevalent in bactericidal than in non-bactericidal sera, although these differences were statistically not significant. Differences in antibody prevalence between carriers of Neisseria spp. and non-carriers of these org ...
IMMUNE RESPONSES AGAINST MYCOBACTERIUM
... responses directed against M.tb associated targets in individuals from Honduras and provides a robust concept for identification of TB targets; we were able to identify differential target recognition patterns in TB+ patients vs TB exposed health care workers. Comprehensive pattern recognition analy ...
... responses directed against M.tb associated targets in individuals from Honduras and provides a robust concept for identification of TB targets; we were able to identify differential target recognition patterns in TB+ patients vs TB exposed health care workers. Comprehensive pattern recognition analy ...
Gene Section MME (membrane metallo-endopeptidase) Atlas of Genetics and Cytogenetics
... 100-kD type II transmembrane glycoprotein originally described on human acute lymphoblastic leukemia cell lines and therefore it was originally designated as common acute lymphocytic leukemia antigen (CALLA). MME is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic resid ...
... 100-kD type II transmembrane glycoprotein originally described on human acute lymphoblastic leukemia cell lines and therefore it was originally designated as common acute lymphocytic leukemia antigen (CALLA). MME is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic resid ...
Detection of a potent humoral response associated with immune
... of immune responses in vivo. Two decades ago, Old demonstrated the reactivity of patient serum with autologous tumor cells, thus providing evidence for a specific humoral response to human cancer cells (15). Autoantibodies have also been used to identify disease-specific molecular targets in autoimm ...
... of immune responses in vivo. Two decades ago, Old demonstrated the reactivity of patient serum with autologous tumor cells, thus providing evidence for a specific humoral response to human cancer cells (15). Autoantibodies have also been used to identify disease-specific molecular targets in autoimm ...
... by inhalation of beryllium dusts. A human leukocyte antigen class II marker (HLADP Glu69) has been found to be strongly associated with the disease. In in vitro studies, the gene has been shown to play a direct role in the immunopathogenesis of the disease. In human studies, the gene has been shown ...
... Furthermore, vaccinated individuals demonstrate considerable variability in their antibody responses to PA. To explore the relationship between PA structure and antigenicity, we produced Escherichia coli strains expressing full-length PA (PA1-4), domains 2 to 4 (PA2-4), domain 1, (PA1), and domain 4 ...
Vaccines
... • A live or inactivated substance capable of producing an immune response Single constituent,e.g.,, polysaccharide or tetanus, ...
... • A live or inactivated substance capable of producing an immune response Single constituent,e.g.,, polysaccharide or tetanus, ...