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OverviewCerebellum
OverviewCerebellum

... the VOR could change if the visual input was perturbed. The classic method for perturbing the visual input was to put a pair of prisms over the eyes. When this is done a head rotation will result in an increased (or decreased dependent on the optics) movement of images across the retina. So the the ...
17 THE CEREBELLUM
17 THE CEREBELLUM

... Afferents: from pons (through MCP) Efferents: to red nucleus but mostly to ventral lateral nucleus of thalamus (through SCP) then to motor cortex Function: coordination of voluntary ...
14-THE CEREBELLUM
14-THE CEREBELLUM

... Afferents: from pons (through MCP) Efferents: to red nucleus but mostly to ventral lateral nucleus of thalamus (through SCP) then to motor cortex Function: coordination of voluntary ...
Powerpoint slides are here
Powerpoint slides are here

...  cells protected by Parkin ...
Cerebrum - ISpatula
Cerebrum - ISpatula

... tracts running between higher and lower neural centers. ...
Bio 17 – Nervous & Endocrine Systems
Bio 17 – Nervous & Endocrine Systems

... ...
Lecture 3
Lecture 3

... • Motor control for muscle coordination and in planning complicated movements • Cognitive tasks involved in learning and memory of motor task. • Lesions to humans or animals shows that distinct areas of the cb are necessary for spatial reasoning, keeping muscle tone during voluntary movement or refl ...
presentation source
presentation source

... ...
Chapter 14 - FacultyWeb
Chapter 14 - FacultyWeb

... Which primary brain vesicle is destined to form the cerebellum, pons, and medulla oblongata? ...
The Cerebellum
The Cerebellum

... – The cerebrocerebellum (neocerebellum), the youngest part, first appears in mammals. – Its inputs arrive mainly from cerebral cortex via the pontine nuclei. – Because of this fact it is also sometimes called the pontocerebellum. – It is richly interconnected, mostly via the ventrolateral (VL) nucle ...
Poster Sensopac
Poster Sensopac

... encoding approach. Each granule cell receives an explicit context signal and three randomly-chosen mossy fibers from current and desired positions and velocities The cerebellum module consists of a network which contains a considerable amount of spiking neurons. To simulate this network efficiently ...
Central Nervous System
Central Nervous System

... Superior colliculi: visual reflex center Inferior colliculi: auditory reflex center ______________________: pigmented neurons in motor fxn and produces the precursor for the neurotransmitter ______________ ...
Objectives 36 - u.arizona.edu
Objectives 36 - u.arizona.edu

... - receives sensory inputs from many areas of body (as well as visual and vestibular sensory info) - cortex associated with movement projects to cerebellum - output of cerebellum projects to motor areas of cerebral cortex (via thalamus) and brainstem - cerebellum has convoluted outer cortex of gray m ...
State Dependant Synaptic Plasticity in Purkinje Cells
State Dependant Synaptic Plasticity in Purkinje Cells

... Department of Neurobiology, Life Science Institute, Hebrew University of Jerusalem, Israel One of the popular theories of cerebellar function assumes that the cerebellum stores memory traces at the parallel fibers (pf) synapse. According to this theory, the climbing fibers (cf) control the learning ...
Draw and describe the circuitry of a cerebellar nucleus: Include
Draw and describe the circuitry of a cerebellar nucleus: Include

... Each Purkinje cell is directly associated with only 1 or 2 climbing fibers [cf] (all climbing fibers come from the inferior olivary nucleus). Each cf makes 300-1000 synaptic contacts with the Purkinje cell they are associated with. Synapses are onto the soma and dendrites of the Purkinje cell. A cf ...
Slide 1
Slide 1

... of each joint along the trajectory and also contextrelated information. Inputs encoding the error are sent (upper downward arrow) through the inferior olive (IO). Cerebellar outputs are provided by the deep-cerebellar-nuclei cells (DCN) (lower downward arrow). The DCN collects activity from the moss ...
The Cerebellum
The Cerebellum

... Function: play an important role in control of muscle tone and coordination of muscle movement on the same side of the body ...
Lateral Zone
Lateral Zone

... These peduncles contain both afferent and efferent fibers. INFERIOR CEREBELLAR PEDUNCLE: – Afferents: these include • posterior spino cerebellar tract • cuneo cerebellar tract which are also called as posterior external arcuate fibers • vestibule cerebellar tracts which are from the vestibular nucle ...
A1987F573800001
A1987F573800001

... of granule cells in relation to the other cellular elements. Most significantly, their leading motile processes were invariably apposed to elongated Bergmann glial fibers. The affinity between these two cell types was implied by the fact that migrating neurons followed a glial fiber while passing by ...
Neuroscience 7c – Basal Ganglia and Cerebellum
Neuroscience 7c – Basal Ganglia and Cerebellum

...  Molecular layer - Cell free – contains only axons and dendrites.  Purkinje cell layer - Its axons are the only output of the cerebellum to the deep nuclei.  Granule cell layer - Granule cells send the axons up to the molecular layer where they end in a T and run parallel to the surface- parallel ...
Cerebellum - DENTISTRY 2012
Cerebellum - DENTISTRY 2012

... between the intermediate zone and the lateral hemisphere that are visible from a gross specimen. ...
Nervous System This week, you will examine the major structures in
Nervous System This week, you will examine the major structures in

... The brain in all vertebrates consists of three parts: the forebrain, the midbrain, and the hindbrain. The main target of this discussion will be the “hindbrain” and its three structures focusing on the functions of the cerebellum. The medulla is located directly above the spinal cord and all the inf ...
The Cerebellum, Basal Ganglia and Overall Motor
The Cerebellum, Basal Ganglia and Overall Motor

... All effrents goes out from deep cerebellar nuceli Vermis--fastigioreticular tract and from cerebellar cortex directly to lateral vestibular nuclei. (i.e vestibular nuclei are functionally deep cerebellar ...
Purkinje cells
Purkinje cells

... The cerebellum operates in 3’s: ...
Cerebellum Learning objectives At the end of this lecture, the
Cerebellum Learning objectives At the end of this lecture, the

... At the end of this lecture, the students will be able to know: • Gross anatomy of the cerebellum • Various terms like folia, vermis, tracts and nuclei of cerebellum • Major efferent and afferent pathways and their function • Human diseases associated with cerebellar dysfunction Some Terminologies Wh ...
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Cerebellum



The cerebellum (Latin for ""little brain"") is a region of the brain that plays an important role in motor control. It may also be involved in some cognitive functions such as attention and language, and in regulating fear and pleasure responses, but its movement-related functions are the most solidly established. The cerebellum does not initiate movement, but it contributes to coordination, precision, and accurate timing. It receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine-tune motor activity. Cerebellar damage produces disorders in fine movement, equilibrium, posture, and motor learning.Anatomically, the cerebellum has the appearance of a separate structure attached to the bottom of the brain, tucked underneath the cerebral hemispheres. Its cortical surface is covered with finely spaced parallel grooves, in striking contrast to the broad irregular convolutions of the cerebral cortex. These parallel grooves conceal the fact that the cerebellar cortex is actually a continuous thin layer of tissue tightly folded in the style of an accordion. Within this thin layer are several types of neurons with a highly regular arrangement, the most important being Purkinje cells and granule cells. This complex neural organization gives rise to a massive signal-processing capability, but almost all of its output passes through a set of small deep cerebellar nuclei lying in the interior of the cerebellum.In addition to its direct role in motor control, the cerebellum is necessary for several types of motor learning, most notably learning to adjust to changes in sensorimotor relationships. Several theoretical models have been developed to explain sensorimotor calibration in terms of synaptic plasticity within the cerebellum. Most of them derive from models formulated by David Marr and James Albus, which were based on the observation that each cerebellar Purkinje cell receives two dramatically different types of input: one type of input is made up of thousands of weak inputs from the parallel fibers; the other type is that of an extremely strong input from a single climbing fiber. The basic concept of the Marr–Albus theory is that the climbing fiber serves as a ""teaching signal"", which induces a long-lasting change in the strength of parallel fiber inputs. Observations of long-term depression in parallel fiber inputs have provided support for theories of this type, but their validity remains controversial.
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