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Chapter 4 : antibiotics and antiseptics
Chapter 4 : antibiotics and antiseptics

... Chemotherapeutic agent act by interfering with the growth of microorganisms. However, they must often act within the host. Therefore, their effects on the cells and tissues of the host are important. The ideal antimicrobial drug kills the harmful microorganism without damaging the host; this is the ...
Periodontal diseases
Periodontal diseases

... •Plaque formation is initiated by a weak attachment of the streptococcal cells to salivary glycoproteins forming a pellicle on the surface of the teeth. • Bacteria adhere to the pellicle, and pellicle coats the ...
plaque - WordPress.com
plaque - WordPress.com

... Formation of the pellicle • Within nanoseconds after a vigorously polishing the teeth, a thin, saliva derived layer called the acquired pellicle, covers the tooth surface. • Consists of more than 180 peptides, proteins, glyco proteins, including keratins, mucins, proline – rich proteins, and other ...
In Vitro and In Vivo Antibacterial Activities of Omadacycline, a Novel
In Vitro and In Vivo Antibacterial Activities of Omadacycline, a Novel

... Omadacycline is distinct from older tetracyclines because it demonstrates in vitro activity against a relatively broad spectrum of organisms, including Gram-positive, Gram-negative, anaerobic, and atypical pathogens, and demonstrates similar in vitro activity against pathogens that express not only ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... essential for enhanced infection control and effective antimicrobial therapy [8]. In view of resistant organisms being reported worldwide, we designed the present study to detect MDR, XDR, PDR and to screen different mechanisms of resistance to beta lactam antibiotics in gram positive and gram negat ...
Get cached PDF
Get cached PDF

... Pseudomonas sp., and Klebsiella sp. were responsible for this syndrome. This research was to promote the uses of traditional medicinal herb as an alternative way to cure repeat breeding. Garlic was as well known as a herb containing antibacterial effects. The objective of this study was to asses the ...
MRSA_6-6-10_jas
MRSA_6-6-10_jas

... as four antibiotics at the same time, e.g. rifampin, ethambutol, isoniazid, and pyrazinamide. In addition, patients are observed taking their medications under a program called “directly observed treatment” (DOT) to insure that the treatment plan is followed. Why is this strategy used? If patients a ...
Cell-wall thickness: possible mechanism of acriflavine resistance in
Cell-wall thickness: possible mechanism of acriflavine resistance in

... differences in individual cell size and cell surface were observed between S. aureus 209P and MRSA KT24. In addition, transmission electron microscopy observations of MRSA KT24 and S. aureus 209P cells at different growth phases (early exponential phase, late exponential phase and stationary phase) ...
The Effect of Silver Nanoparticles Size, Produced Using Plant
The Effect of Silver Nanoparticles Size, Produced Using Plant

... variations against the gram-negative species Escherichia coli (Ec) and Pseudomonas aeruginosa (Pa), as well as the gram-positive species Bacillus subtilis (Bs) and Staphylococcus epidermidis (Se). By means of Scanning Electron Microscopy (SEM) we visualize the morphological changes of Escherichia co ...
PDF - Journal of Applied Pharmaceutical Science
PDF - Journal of Applied Pharmaceutical Science

... plants have evoked interest as source of natural products. They have been screened for their potential uses as alternative remedies for the treatment of many infectious diseases (Tepe et al., 2004).The present work aims at the isolation and identification of bacteria infecting urinary tract and test ...
(L.) Vahl CRUDE PLANT EXTRACTS KU ANIS SHAZURA BT IND
(L.) Vahl CRUDE PLANT EXTRACTS KU ANIS SHAZURA BT IND

... have other important roles making them an attractive thing to be explored by the researcher. They grab the attention of the researchers by showing some medicinal properties. These medicinal plants have been used for centuries as remedies and the richest bio-resources of drugs of traditional medicina ...
Projektets Formål
Projektets Formål

... Anette M. Hammerum National Center for Antimicrobials and Infection Control Statens Serum Institut, Copenhagen, Denmark ...
Insect-Derived Cecropins Display Activity against
Insect-Derived Cecropins Display Activity against

... bacterium that has recently emerged as a dangerous nosocomial pathogen (1–4). An increasing number of A. baumannii infections in patients have been detected among U.S. military service members injured in Iraq and Afghanistan (5). The genetic adaptability of A. baumannii allows it to gain resistance ...
Alternative therapies in Staphylococcus aureus diseases
Alternative therapies in Staphylococcus aureus diseases

... producing strains as is indicated by its low ampicillin MIC. Hong et al. (2006) studied the inhibitory activity of genistein, a radioprotective soy isoflavone, against opportunistic S. aureus that could cause sepsis in patients after radiotherapy. S. aures culture (1 × 103 CFU/ml) was treated with 1 ...
Significance of biocide usage and antimicrobial resistance in
Significance of biocide usage and antimicrobial resistance in

... When assessing the significance of antimicrobial resistance it is important to bear in mind that the term ‘resistance’ is a relative word. The microbicidal action of biocides (as opposed to antibiotics) results from their interaction with a number of distinct biochemical targets on or in the cell. S ...
Full Text PDF - Jaypee Journals
Full Text PDF - Jaypee Journals

... Bacteriophages are bacterial vs that invade bacterial cells and are among the most abundant lining entities on earth playing important roles in maintaining the natural abundance and distribution of microorganisms. Phage therapy for eliminating multidrug resistant bacteria is gaining importance. Ther ...
Prevalence of Etiological Agents and Antimicrobial Resistance
Prevalence of Etiological Agents and Antimicrobial Resistance

... terial meningitis often presents nonspecific signs and symptoms, especially in neonates; therefore, empirical antimicrobial therapy should be initiated based on low clinical suspicion until CSF culture results would be prepared (1). Empirical antibiotic treatment is advised in cases of suspected men ...
True bacteria –Cocci- Gram positive cocci Staphylococci (A
True bacteria –Cocci- Gram positive cocci Staphylococci (A

... of humans; others cause abscess formation, a variety of pyogenic infections, and even fatal septicemia.The pathogenic Staphylococci often hemolyze blood, coagulate plasma, and produce a variety of extracellular enzymes and toxins. The most common type of food poisoning is caused by a heat-stable sta ...
How to Diagnose Common Equine Reproductive Tract Bacterial
How to Diagnose Common Equine Reproductive Tract Bacterial

... Good growth, Large purple/deep blue/metallic navy colonies. 2–4 mm. Good growth, darkish pink colonies. 2–3 mm. Good growth, light blue colonies. 0.5–1 mm. Good growth, white colonies. Oxidase negative, always Catalase positive. 2–3 mm. Dark blue/navy colonies. Similar but subjectively smaller than ...
Biofilms
Biofilms

... of cvstic fibrosis patients, Psciidoinonas aeruginosa frequently forms biofilms that cause potentially lethal pneumonias. There is a long list of biofilmrelated ailments, and many scientists ...
Antimicrobial Properties of Chili Peppers - e
Antimicrobial Properties of Chili Peppers - e

... of quality health data and information. There are also new concerns about food safety due to increasing occurrences of new food-borne disease outbreaks caused by pathogenic microorganisms. This raises considerable challenges, particularly since there is increasing unease regarding the use of chemica ...
L-Lactic Acid – A Safe Antimicrobial for Home- and
L-Lactic Acid – A Safe Antimicrobial for Home- and

... combinations of Lactic Acid and surfactants act as broad spectrum antibacterial formulations. This is best understood from the perspective that surfactants can weaken the bacterial cell membrane. Many of the molecular events that lead to bacterial inactivation by organic acid action involve the cell ...
Bacterial resistance to silver in wound care
Bacterial resistance to silver in wound care

... relatively safe and exhibits broad-spectrum antimicrobial activity.30–34 ...
Novel therapies for treatment of multidrug- Acinetobacter baumannii Mircea Radu Mihu
Novel therapies for treatment of multidrug- Acinetobacter baumannii Mircea Radu Mihu

... in our skin, has recently been associated with enhanced Ab multidrug resistance.26 Carbapenem resistance is the best example that demonstrates the variety of mechanisms that provide resistance of Ab to a particular group of antibiotics.12 This microbe produces metallo-β-lactamases (VIM-, IMP- and SI ...
the ultrastructure of prokaryotic
the ultrastructure of prokaryotic

... 7, 8). The bacterial cell envelopes consist of a plasma membrane (bpm), a dense peptidoglycan layer (d) (not visible in the fusiform bacteria), and an outer membrane (bom) and glycocalyx (g). The rod bacteria bear a thick glycocalyx andflagella(/) only on the exposed part of their surface at the poc ...
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Antimicrobial surface

An antimicrobial surface contains an antimicrobial agent that inhibits or reduces the ability of microorganisms to grow on the surface of a material. Such surfaces are becoming more widely investigated for possible use in various settings including clinics, industry, and even the home. The most common and most important use of antimicrobial coatings has been in the healthcare setting for sterilization of medical devices to prevent hospital associated infections, which have accounted for almost 100,000 deaths in the United States. In addition to medical devices, linens and clothing can provide a suitable environment for many bacteria, fungi, and viruses to grow when in contact with the human body which allows for the transmission of infectious disease.Antimicrobial surfaces are functionalized in a variety of different processes. A coating may be applied to a surface that has a chemical compound which is toxic to microorganism. Other surfaces may be functionalized by attaching a polymer, or polypeptide to its surface.An innovation in antimicrobial surfaces is the discovery that copper and its alloys (brasses, bronzes, cupronickel, copper-nickel-zinc, and others) are natural antimicrobial materials that have intrinsic properties to destroy a wide range of microorganisms. An abundance of peer-reviewed antimicrobial efficacy studies have been published regarding copper’s efficacy to destroy E. coli O157:H7, methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus, Clostridium difficile, influenza A virus, adenovirus, and fungi. For further information regarding efficacy studies, clinical studies (including U.S. Department of Defense clinical trials), United States Environmental Protection Agency (EPA) registrations with public health claims for 355 Antimicrobial Copper (Cu+) alloys, and a list of EPA-registered antimicrobial copper products, see: Antimicrobial copper touch surfaces and Antimicrobial properties of copper.Apart from the health industry, antimicrobial surfaces have been utilized for their ability to keep surfaces cleaned. Either the physical nature of the surface, or the chemical make up can be manipulated to create an environment which cannot be inhabited by microorganisms for a variety of different reasons. Photocatalytic materials have been used for their ability to kill many microorganisms and therefore can be used for self-cleaning surfaces as well as air cleaning, water purification, and antitumor activity.
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