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Timed Sequential Treatment With Cyclophosphamide, Doxorubicin
Timed Sequential Treatment With Cyclophosphamide, Doxorubicin

... clinical success is most likely due to suboptimal immunization strategies that fail to consider immune tolerance and disease burdens, inadequate targets, or both.3 Tumor cells genetically modified to express granulocytemacrophage colony-stimulating factor (GM-CSF) can induce potent T-cell– dependent ...
Natural cutaneous anthrax infection, but not vaccination, induces a CD4
Natural cutaneous anthrax infection, but not vaccination, induces a CD4

... vaccination, is not unprecedented; Mycobacterium tuberculosis infection results in high levels of mycobacteria-specific IL-17 [37] and IL-9 [38] produced by T cells, whereas in recent clinical trials of the MVA85A vaccine, only extremely high doses induced a significant increase in IL-17 production, ...
4TH ANNUAL MEETING OF THE INTERNATIONAL CYTOKINE AND
4TH ANNUAL MEETING OF THE INTERNATIONAL CYTOKINE AND

... Dr Belkaid is a world-leader in the areas of cytokine regulation of host defense, inflammation and tissue protection. Her research has spanned areas of immunity to infection, host-microbiota interactions and regulation of effector and regulatory T cell function. Dr Belkaid is an outstanding speaker ...
Your Immune System -Why It Fails & How To Fix It
Your Immune System -Why It Fails & How To Fix It

... through this process, the system is kept in check so that it does not overreact. For should this occur, Allergies or worse yet, Autoimmune Disease may be the result. Due to lack of proper nutrients from the daily diet, combined with the ever increasing number of synthetic foreign chemicals, not foun ...
Glycobiology of the Immune Response, Volume 1253. Annals of the... Academy of Sciences Brochure
Glycobiology of the Immune Response, Volume 1253. Annals of the... Academy of Sciences Brochure

... Carbohydrates are ubiquitous, essential molecules, as important as nucleic acids and proteins yet less well understood. Mounting data demonstrate that microbial and mammalian glycans and their protein–binding partners (lectins) play central roles in all innate and adaptive immune responses. Indeed, ...
Allergy and immunity to fungal infections and colonization
Allergy and immunity to fungal infections and colonization

... concomitantly present. In the past, most fungi could be assigned to these two categories. However, recent findings clearly show that these two categories do not sufficiently discriminate among these species. For example, Saccharomyces cerevisiae, considered to be the least dangerous fungal species, ...
Do all creatures possess an acquired immune system of some sort?
Do all creatures possess an acquired immune system of some sort?

... mammalian immune system prepares in advance a large variety of randomly made somatic T-cell receptors (TCR), carried by T cells, using the innate RAG1/2 mechanism. Here, the T-cell receptors serve as acquired immune recognition molecules, and specificity is provided by the sequence and structure uni ...
LECTURE 1 INTRODUCTION TO IMMUNOLOGY I Definition of
LECTURE 1 INTRODUCTION TO IMMUNOLOGY I Definition of

... The humoral (antibody) response is defined as the interaction between antibodies and antigens. Antibodies are specific proteins released from a certain class of immune cells (B lymphocytes). Antigens are defined as anything that elicits generation of antibodies, hence they are Antibody Generators. I ...
Headache and The Immune System
Headache and The Immune System

... The immune system exists to prevent invasion of the body by infection. Immune system cells constantly patrol the bloodstream and brain, seeking to kill foreign organisms such as bacteria. The immune system is a vastly complicated latticework of different parts, some of which directly attack foreign ...
Standing orders for administering hepatitis B vaccine to adults
Standing orders for administering hepatitis B vaccine to adults

...  or persons born in Asia, the Pacific Islands, Africa, or other countries identified as having high rates of HBV F infection (see MMWR 2005;54[RR-16]:25), ensure that they have also been tested for hepatitis B surface antigen (HBsAg) to find out if they are chronically infected. If test is performe ...
CDC Recommended Adult Immunization Schedule
CDC Recommended Adult Immunization Schedule

... 2. Human papillomavirus (HPV) vaccination. HPV vaccination is recommended at age 11 or 12 years with catch-up vaccination at ages 13 through 26 years. Ideally, vaccine should be given before potential exposure to HPV through sexual activity; however, females who are sexually active should still be ...
History of Discovery - Arteriosclerosis, Thrombosis, and Vascular
History of Discovery - Arteriosclerosis, Thrombosis, and Vascular

... rules: (1) they are absent from the host, allowing discrimination between self and nonself; (2) they are conserved among large numbers of microorganisms, allowing recognition of a wide array of microorganisms by a limited number of receptors; and (3) they are essential constituents of the microorgan ...
Saskatchewan Immunization Manual
Saskatchewan Immunization Manual

... different of class of antibody with the same antigenic specificity; this process is also reflected in the class  switch from IgM to IgG that is seen during the maturation of an immune response.  Clonal expansion/proliferation ‐ When an antigen stimulates a specific lymphocyte, clones or identical  d ...
Children`s Immune System
Children`s Immune System

... them and new, deadlier organisms, like the powerful drug-resistant tuberculosis strain, have been emerging as a result.” JEFFREY FISHER, MD “Chronic middle ear problems in children have not diminished, despite the number of antibiotics being used to treat them. We have created a whole new kind of ea ...
Corps Member - TFA
Corps Member - TFA

... HPV is very common. Most people who have sex will develop an HPV infection at some point in their lives. There are more than 100 different types of HPV. Some types can cause genital warts, and about 15 types can cause cervical cancer. Most people who get HPV do not even know it. Often, they find out ...
Wobenzym - Henderson Chiropractic Clinic
Wobenzym - Henderson Chiropractic Clinic

... Therapeutic challenges attendant to the complexity of the immune response alluded to initially, and the critical role it plays in an array of chronic, proliferative diseases, a paradigm shift is gradually taking hold in healthcare. The once standard approach to target a specific step in a biochemic ...
Lymphatic System - SCF Faculty Site Homepage
Lymphatic System - SCF Faculty Site Homepage

... Foreign (non-self) cells or chemicals that produce an immune response (stimulate antibody production)  Are microbes, parts of microbes, blood cells, transplant tissues, and a variety of chemicals ...
CHAPTER 1  INTRODUCTION
CHAPTER 1 INTRODUCTION

... Heartwater is characterised by fever, neurological signs, hydropericardium, hydrothorax and lung oedema. The vector for this parasite in Kenya is Amblyomma variegatum. Transstadial transmission occurs in this three-host tick. Young calves have an age-related resistance to disease which lasts about f ...
FMD
FMD

... which infected individuals recover and gain permanent immunity from subsequent infection. For the case of FMD infected animals did not recover, rather they were slaughtered. However, this has the same effect; the removal of infected animals from the population. Within the model we consider the popul ...
PROPHYLAXIS OF TUBERCULOSIS
PROPHYLAXIS OF TUBERCULOSIS

... methods with 2-3 months intervals (during 10-12 months from the moment of the examination negative result); 2) at chronic pulmonary tuberculosis, when the cessation of bacterial excretion as a result of treatment is confirmed by repeated examinations with bacterioscopic and cultural methods with 2-3 ...
The central role of immunity in the symbiotic event referred as
The central role of immunity in the symbiotic event referred as

... i) Coevolution can occur between any interacting populations, for instance between prey-predator, host-pathogen, etc. This event is very important because this association provokes selective pressures of one on the other participants resulting in different effects on their fitness inducing benefits; ...
measles - Network for Education and Support in Immunisation
measles - Network for Education and Support in Immunisation

... Of the 10% -15% remaining unprotected, 95% will develop immunity after a second dose. Therefore, a second dose is advised. Programs that provide 2 doses of measles vaccine have been found to be highly cost-effective, regardless of the method used to deliver the doses (in the routine healthcare or wi ...
Combating Infections
Combating Infections

... (the part that stimulates an immune response). • The vaccines for Hepatitis B and Streptococcus pneumoniae are subunit vaccines. ...
Disease ecology meets ecological immunology
Disease ecology meets ecological immunology

... of synergy between the two fields, including the role of Regoes 2009). For example, individual variation in infectioussuperspreaders and key hosts in the dynamics of infectious ness is commonly observed for many pathogens, with sudisease, the influence of environmental factors such as climate persprea ...
Guillain-Barré syndrome following hepatitis B vaccination
Guillain-Barré syndrome following hepatitis B vaccination

... developed GBS 3 and 9 months after the last injection. Their conclusion was that the vaccine was safe and that the incidence of GBS was not increased. The authors claimed that the adverse events caused by the plasma-derived HBV vaccine are due to the preservative material thimerosal, a mercurial com ...
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Herd immunity



Herd immunity (also called herd effect, community immunity, population immunity, or social immunity) is a form of indirect protection from infectious disease that occurs when a large percentage of a population has become immune to an infection, thereby providing a measure of protection for individuals who are not immune. In a population in which a large number of individuals are immune, chains of infection are likely to be disrupted, which stops or slows the spread of disease. The greater the proportion of individuals in a community who are immune, the smaller the probability that those who are not immune will come into contact with an infectious individual.Individual immunity can be gained through recovering from a natural infection or through artificial means such as vaccination. Some individuals cannot become immune due to medical reasons and in this group herd immunity is an important method of protection. Once a certain threshold has been reached, herd immunity will gradually eliminate a disease from a population. This elimination, if achieved worldwide, may result in the permanent reduction in the number of infections to zero, called eradication. This method was used for the eradication of smallpox in 1977 and for the regional elimination of other diseases. Herd immunity does not apply to all diseases, just those that are contagious, meaning that they can be transmitted from one individual to another. Tetanus, for example, is infectious but not contagious, so herd immunity does not apply.The term herd immunity was first used in 1923. It was recognized as a naturally occurring phenomenon in the 1930s when it was observed that after a significant number of children had become immune to measles, the number of new infections temporarily decreased, including among susceptible children. Mass vaccination to induce herd immunity has since become common and proved successful in preventing the spread of many infectious diseases. Opposition to vaccination has posed a challenge to herd immunity, allowing preventable diseases to persist in or return to communities that have inadequate vaccination rates.
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