Infectious Diseases Fall 2003 - American Academy of Pediatrics
... The concept of “cocooning” to prevent serious pertussis infection in infants by vaccinating all close contacts and caregivers was discussed at the March, 2012 Cocooning Expert Meeting convened by the American Academy of Pediatrics (AAP). The experts reviewed the challenges, potential solutions and n ...
... The concept of “cocooning” to prevent serious pertussis infection in infants by vaccinating all close contacts and caregivers was discussed at the March, 2012 Cocooning Expert Meeting convened by the American Academy of Pediatrics (AAP). The experts reviewed the challenges, potential solutions and n ...
BVGH - Who We Are
... Dengue infection leads to multiple non-specific symptoms such as high fever, rash, and joint pain. It is unclear why, but a small percentage of dengue patients progress to DHF, which is further classified as DSS in its most advanced stages. The majority of DHF/DSS cases occur in children under the a ...
... Dengue infection leads to multiple non-specific symptoms such as high fever, rash, and joint pain. It is unclear why, but a small percentage of dengue patients progress to DHF, which is further classified as DSS in its most advanced stages. The majority of DHF/DSS cases occur in children under the a ...
Effects of Indoor Air Pollution on Human Health
... For some groups of effects, clear relationships with exposure to IAP have been reported in the world literature. Among these are respiratory disease (particularly among children), allergy (particularly to house dust mites) and mucous membrane irritation (particularly due to formaldehyde). Large numb ...
... For some groups of effects, clear relationships with exposure to IAP have been reported in the world literature. Among these are respiratory disease (particularly among children), allergy (particularly to house dust mites) and mucous membrane irritation (particularly due to formaldehyde). Large numb ...
Fever - Meridian Kinesiology
... may experience one if his temperature is allowed to rise too high. High fevers do not cause convulsions. They result when the temperature rises at an extremely rapid rate and are relatively uncommon. It is estimated that only 4 percent of children with high fever experience fever related convulsions ...
... may experience one if his temperature is allowed to rise too high. High fevers do not cause convulsions. They result when the temperature rises at an extremely rapid rate and are relatively uncommon. It is estimated that only 4 percent of children with high fever experience fever related convulsions ...
John Salamone: Dopamine, Motivation and Schizophrenia
... antipsychotic drugs are directly related to their clinical effects DA mediates “motivational salience” or “motivational significance” • DA mediates instrumental responses to appetitive and aversive events • DA antagonists “change the drive to obtain food and sex” or “decrease motivational drive” • D ...
... antipsychotic drugs are directly related to their clinical effects DA mediates “motivational salience” or “motivational significance” • DA mediates instrumental responses to appetitive and aversive events • DA antagonists “change the drive to obtain food and sex” or “decrease motivational drive” • D ...
THE SECTION ON INFECTIOUS DISEASES
... are improved antivirals that have fewer toxicities than cidofovir, a better understanding of how to interpret blood adenovirus quantitative PCR tests so as to predict response to antivirals, and better prevention strategies such as adenoviral vaccine development. Since there are reports of mother-to ...
... are improved antivirals that have fewer toxicities than cidofovir, a better understanding of how to interpret blood adenovirus quantitative PCR tests so as to predict response to antivirals, and better prevention strategies such as adenoviral vaccine development. Since there are reports of mother-to ...
... Advisory Group on Immunisation recommends that this brand of vaccine should not be used in children aged <10 years (see Precautions and Further information (b)). Immunisation providers can choose from one of four other brands of influenza vaccine which are registered and recommended for use in young ...
Yukon Communicable Disease Control
... Identify the specimen as “acute measles” on the lab requisition. Acute measles serology includes testing for measles specific IgM and IgG class antibodies. Request that sera from probable cases of measles be tested for antibody to parvovirus B19 and rubella. Request these tests on the initial ACUTE ...
... Identify the specimen as “acute measles” on the lab requisition. Acute measles serology includes testing for measles specific IgM and IgG class antibodies. Request that sera from probable cases of measles be tested for antibody to parvovirus B19 and rubella. Request these tests on the initial ACUTE ...
Informed consent and clinical trials: where is the placebo effect?
... Improving standards of disclosure about placebo effects in clinical trials could help reduce therapeutic misconceptions among participants. One approach is to develop generic information leaflets that describe placebos and explain placebo effects in accessible terms,22 elaborating on the information ...
... Improving standards of disclosure about placebo effects in clinical trials could help reduce therapeutic misconceptions among participants. One approach is to develop generic information leaflets that describe placebos and explain placebo effects in accessible terms,22 elaborating on the information ...
HIV/AIDS: Opportunities to Address Pharmaceutical
... Multiple ART drug combinations continue to successfully reduce viral load and restore immune responses in many HIV-infected individuals. However, these regimens also can result in serious toxicities and side effects, single- and multiple drug-resistance, and other complications that make them unacce ...
... Multiple ART drug combinations continue to successfully reduce viral load and restore immune responses in many HIV-infected individuals. However, these regimens also can result in serious toxicities and side effects, single- and multiple drug-resistance, and other complications that make them unacce ...
The Expanding Role of Aerosols in Systemic Drug Delivery, Gene
... inhalation therapy focused primarily on the treatment of asthma and chronic obstructive pulmonary disease, and the pressurized metered-dose inhaler was the delivery device of choice. However, the role of aerosol therapy is clearly expanding beyond that initial focus. This expansion has been driven b ...
... inhalation therapy focused primarily on the treatment of asthma and chronic obstructive pulmonary disease, and the pressurized metered-dose inhaler was the delivery device of choice. However, the role of aerosol therapy is clearly expanding beyond that initial focus. This expansion has been driven b ...
Meningococcal Disease Information and Investigation Guidelines Table of Contents:
... puncture and blood sample should be taken immediately prior, or concurrently to starting antibiotic therapy. CSF and blood cultures should be started as soon as possible to attempt to identify the infectious agent, as results may take up to 48 hours. Gram stains should immediately be done in effort ...
... puncture and blood sample should be taken immediately prior, or concurrently to starting antibiotic therapy. CSF and blood cultures should be started as soon as possible to attempt to identify the infectious agent, as results may take up to 48 hours. Gram stains should immediately be done in effort ...
2009 H1N1 Influenza General Talking Points
... o If you decide you need to talk to a health care provider, take steps to avoid exposing others to the flu: Call first to see if you need to actually see your provider in person. If you do need to see your provider, steps can be taken to avoid exposing other patients to the flu. o If you have po ...
... o If you decide you need to talk to a health care provider, take steps to avoid exposing others to the flu: Call first to see if you need to actually see your provider in person. If you do need to see your provider, steps can be taken to avoid exposing other patients to the flu. o If you have po ...
Smallpox Virus - Cal State LA
... • Has a history of being tested and probably manipulated for bioweapons possibilities for at least a couple decades. • Cheap and easy to make and administer to unsuspecting populations. • Highly contagious- need relatively small amount of virus to cause a epidemic outbreak. • 2 week incubation perio ...
... • Has a history of being tested and probably manipulated for bioweapons possibilities for at least a couple decades. • Cheap and easy to make and administer to unsuspecting populations. • Highly contagious- need relatively small amount of virus to cause a epidemic outbreak. • 2 week incubation perio ...
Vaccines
... even those who did not receive the vaccine, or those who did not receive immunity from the vaccine, benefit from vaccination and will be protected from the disease. This is known as herd immunity—where sufficient immunization coverage prevents the transmission of the disease to an otherwise suscepti ...
... even those who did not receive the vaccine, or those who did not receive immunity from the vaccine, benefit from vaccination and will be protected from the disease. This is known as herd immunity—where sufficient immunization coverage prevents the transmission of the disease to an otherwise suscepti ...
2006 Feline Vaccine Guidelines - American Association of Feline
... killer cells, and age, prevents most pathogens from infecting and causing disease in animals. Innate immunity is the first line of defense; thus, it is already active or immediately activated in response to inherent or elaborated chemical substances of the infectious agent.2-6 Acquired immunity is c ...
... killer cells, and age, prevents most pathogens from infecting and causing disease in animals. Innate immunity is the first line of defense; thus, it is already active or immediately activated in response to inherent or elaborated chemical substances of the infectious agent.2-6 Acquired immunity is c ...
COPD: FIXING the FIXABLES in 2003
... Prevalence 5.9% of U.S. population or about 24,000,000 adults (ATS Gold Paper 2004) In 2000 there were 122,000 deaths (CDC data) For the first time more women than men 2nd to heart disease as a cause of disability Annual cost 2002 est. $32.1 billion 70% of the patients were less than 65 ...
... Prevalence 5.9% of U.S. population or about 24,000,000 adults (ATS Gold Paper 2004) In 2000 there were 122,000 deaths (CDC data) For the first time more women than men 2nd to heart disease as a cause of disability Annual cost 2002 est. $32.1 billion 70% of the patients were less than 65 ...
The Smallpox Vaccination Campaign of 2003: Why Bioterrorism Preparedness?
... history.28 In most communities, however, the damage done by any given epidemic was limited because many people would be immune to the disease because of prior exposure. As vaccination became more common in the late nineteenth century, it dramatically reduced the number of persons infected during epi ...
... history.28 In most communities, however, the damage done by any given epidemic was limited because many people would be immune to the disease because of prior exposure. As vaccination became more common in the late nineteenth century, it dramatically reduced the number of persons infected during epi ...
Septic Shock - Calgary Emergency Medicine
... Prospective RCT of 263 adult pts with sepsis treated either with traditional care or a standardized resuscitation protocol in the ED All had arterial & central venous lines placed – the EGDT group got a catheter capable of ...
... Prospective RCT of 263 adult pts with sepsis treated either with traditional care or a standardized resuscitation protocol in the ED All had arterial & central venous lines placed – the EGDT group got a catheter capable of ...
SEDATIVE-HYPNOTICS: Barbiturates (p.1) History these drugs were
... SEDATIVE-HYPNOTICS: Barbiturates (p.1) History these drugs were the major tx option for anxiety & insomnia from 1912 to 1960 they were very likely to be abused often used in suicide and attempted suicide caused accidental deaths in Ss who took them w/ ETOH or in combination with other S-Hs 1.Pharmac ...
... SEDATIVE-HYPNOTICS: Barbiturates (p.1) History these drugs were the major tx option for anxiety & insomnia from 1912 to 1960 they were very likely to be abused often used in suicide and attempted suicide caused accidental deaths in Ss who took them w/ ETOH or in combination with other S-Hs 1.Pharmac ...
It is recommended that the MAH shall submit the PSUR data in
... patients exposed. In particular, during the early post marketing period the product might be used in settings different from clinical trials and a much larger population might be exposed in a relatively short timeframe. Once a product is marketed, new information will be generated, which can have an ...
... patients exposed. In particular, during the early post marketing period the product might be used in settings different from clinical trials and a much larger population might be exposed in a relatively short timeframe. Once a product is marketed, new information will be generated, which can have an ...
COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE (CHMP)
... results from a complex interplay between such factors as route of administration, antigen dose and the nature of the antigen. For this reason, a final safety evaluation of the newly developed vaccine formulation can only be conducted on the basis of clinical trials. 2. SCOPE This Guideline addresses ...
... results from a complex interplay between such factors as route of administration, antigen dose and the nature of the antigen. For this reason, a final safety evaluation of the newly developed vaccine formulation can only be conducted on the basis of clinical trials. 2. SCOPE This Guideline addresses ...
It is recommended that the MAH shall submit the PSUR
... patients exposed. In particular, during the early post marketing period the product might be used in settings different from clinical trials and a much larger population might be exposed in a relatively short timeframe. Once a product is marketed, new information will be generated, which can have an ...
... patients exposed. In particular, during the early post marketing period the product might be used in settings different from clinical trials and a much larger population might be exposed in a relatively short timeframe. Once a product is marketed, new information will be generated, which can have an ...
Chapter 4 - Children`s Healthcare of Atlanta
... To prevent spreading infection for all eye, ear, nose, throat and chest diseases: Good hand-washing and hygiene; proper disposal of soiled tissues; avoid sharing linens; proper disinfection of surfaces and toys; cough into elbow or clothing when tissues unavailable ...
... To prevent spreading infection for all eye, ear, nose, throat and chest diseases: Good hand-washing and hygiene; proper disposal of soiled tissues; avoid sharing linens; proper disinfection of surfaces and toys; cough into elbow or clothing when tissues unavailable ...
Non-specific effect of vaccines
Non-specific effects of vaccines (also called “heterologous effects"" or ""off-target effects"") are effects which go beyond the specific protective effects against the targeted diseases. Non-specific effects can be strongly beneficial, increasing protection against non-targeted infections, but also at times negative, increasing susceptibility to non-targeted infections. This depends on both the vaccine and the sex of the infant.All live attenuated vaccines studied so far (BCG vaccine, measles vaccine, oral polio vaccine, smallpox vaccine) have been shown to reduce mortality more than can be explained by prevention of the targeted infections. In contrast, inactivated vaccines (diphtheria-tetanus-pertussis vaccine (DTP), hepatitis B vaccine, inactivated polio vaccine) may increase overall mortality despite providing protection against the target diseases.These effects may be long-lasting, at least up to the time point where a new type of vaccine is given. The non-specific effects can be very pronounced, with significant effects on overall mortality and morbidity. In a situation with herd immunity to the target disease, the non-specific effects can be more important for overall health than the specific vaccine effects.The non-specific effects should not be confused with the side effects of vaccines (such as local reactions at the side of vaccination or general reactions such as fever, head ache or rash, which usually resolve within days to weeks - or in rare cases anaphylaxis). Rather, non-specific effects represent a form of general immunomodulation, with important consequences for the immune system’s ability to handle subsequent challenges.It is estimated that millions of child deaths in low income countries could be prevented every year if the non-specific effects of vaccines were taken into consideration in immunization programs.