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How do viruses differ?
How do viruses differ?

... The International Committee on Taxonomy of Viruses (ICTV) developed the current classification system and put in place guidelines that put a greater weighting on certain virus properties in order to maintain family uniformity. A universal system for classifying viruses, and a unified taxonomy, has b ...
HIV and AIDS
HIV and AIDS

ppt
ppt

... usually not all sites in a sequence are under selection all the time. PAML (and other programs) allow to either determine omega for each site over the whole tree, ...
do not write on the paper
do not write on the paper

... toxin or poison) is a microscopic organism consisting of genetic material (RNA or DNA) surrounded by a protein, lipid (fat), or glycoprotein coat. Some microbiologists classify viruses as microorganisms, while others don't because they are "nonliving" and describe viruses as microscopic infective ag ...
Microorganisms Power Point
Microorganisms Power Point

... energy because they lack mitochondria. They have to derive their energy from the host cell. They also parasitize the cell for basic building materials, such as amino acids, nucleotides, and lipids (fats). ...
ppt
ppt

... usually not all sites in a sequence are under selection all the time. PAML (and other programs) allow to either determine omega for each site over the whole tree, ...
What is Population Genetics?
What is Population Genetics?

... • The possible range for an allele frequency or genotype frequency therefore lies between ( 0 – 1) • with 0 meaning complete absence of that allele or genotype from the population (no individual in the population carries that allele or genotype) • 1 means complete fixation of the allele or genotype ...
Final Lecture
Final Lecture

... • The possible range for an allele frequency or genotype frequency therefore lies between ( 0 – 1) • with 0 meaning complete absence of that allele or genotype from the population (no individual in the population carries that allele or genotype) • 1 means complete fixation of the allele or genotype ...
mv-lect-3-virus-genomes
mv-lect-3-virus-genomes

... its susceptibility to Ribonuclease (e.g., RNAse A, H, T) or deoxyribonuclease (e.g., DNAse 1, or S1 Nuclease). • The virus nucleic acid will be susceptible to degradation by only one of these enzymes. ...
ppt - Gogarten Lab
ppt - Gogarten Lab

... usually not all sites in a sequence are under selection all the time. PAML (and other programs) allow to either determine omega for each site over the whole tree, ...
Enter Topic Title in each section above
Enter Topic Title in each section above

... A. Contains the enzyme lysozyme – A. Bacteriophage; Used in genetic a bactericidal agent; Continuous engineering; Vaccine production; unbroken covering Vector in disease treatment Q. What is the purpose of vaccination? ...
Mutationism, Neutralism, Selectionism
Mutationism, Neutralism, Selectionism

... mutational input and a concomitant random extinction or fixation of alleles. ...
infection data: why, when, and what to report?
infection data: why, when, and what to report?

... results for viral loads • Pathology: histopathology or other tissue diagnoses for various infections • Radiology: imaging studies, particularly for CT scan findings for fungal infections • Progress notes ...
AIDS
AIDS

... • Virus causes lytic infection of CD4 T cells and persistent low-level productive infection of macrophage lineage cells. • Virus causes syncytia formation, with cells expressing large amounts of CD4 antigen (T cells) with subsequent lysis of the cells. • Virus alters T-cell and macrophage cell funct ...
Molecular Phylogenetic Analysis: Design and Implementation of
Molecular Phylogenetic Analysis: Design and Implementation of

... selected, the first step is to align them [1,2]. The difference in lengths can appear due to sequencing errors (digitalizing the biological sample), mutations (insertions or deletions of one or more sites along the sequence) or because the researcher also wants to include fragments of the same genet ...
Low DNA HTLV-2 proviral load among women in S˜ao Paulo City
Low DNA HTLV-2 proviral load among women in S˜ao Paulo City

... former IDU, and 2 of them were co-infected with HIV-1. In contrast, men had a mean number of 43 copies/104 PBMC and 181 copies/104 PBMC, for the co-infected and singly, respectively, p < 0.05). Co-infected men were more likely to be IDU than women (p = 0.03), but singly infected men for HTLV-2 were ...
11.1 Genetic Variation Within Population
11.1 Genetic Variation Within Population

... Natural selection can change the distribution of a trait in one of three ways. • Microevolution is evolution within a population. – observable change in the allele frequencies – can result from natural selection ...
Background: Terrorists Release Sarin nerve agent (GB) in
Background: Terrorists Release Sarin nerve agent (GB) in

... Psychosocial Impact • After months of steady outbreaks, few lives are untouched by illness, death, bereavement, and stress. ...
here
here

... Evolution occurs within populations where the fittest organisms have a selective advantage. Over time the advantages genes become fixed in a population and the population gradually changes. Note: this is not in contradiction to the the theory of neutral evolution. (which says what ?) Processes that ...
Chapter 13 Evolution and human health
Chapter 13 Evolution and human health

... are three general models to explain the evolution of virulence.  (1) The coincidental evolution hypothesis. Virulence of some pathogens in humans may not be a target of selection at all. Instead, it may be an accidental result of selection on other traits. ...
Patterns in genomic chaos: bacterial cells as vehicles of war in
Patterns in genomic chaos: bacterial cells as vehicles of war in

... !  No need to ask “why bacteria exchange genetic material if it is not evolutionarily favorable for them” (i.e. EHEC epidemic in Germany 2011) ...
Document
Document

... 2*(1 + 1/2 + 1/3 +..+ 1/(k-1)) ca= 2*ln(k-1) ...
Infection Prevention and Control Guidelines for Seasonal Influenza
Infection Prevention and Control Guidelines for Seasonal Influenza

... commencing anti-influenza medications for individual patients. ● Laboratory testing is recommended for: o a representative sample of ILI patients from the surveillance systems. o people with severe influenza-like illness who are hospitalized. o outbreaks in high-risk settings where individuals are a ...
Human Immunodeficieny virus
Human Immunodeficieny virus

... showing. ...
Microbes and Protists
Microbes and Protists

... A virus is a tiny, non-living particle that enters and then reproduces inside of a living cell.  A virus may have DNA or RNA  Many shapes of viruses.  Size: 10-1,000 nanometers ...
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Viral phylodynamics



Viral phylodynamics is defined as the study of how epidemiological, immunological, and evolutionary processes act and potentially interact to shape viral phylogenies.Since the coining of the term in 2004, research on viral phylodynamics has focused on transmission dynamics in an effort to shed light on how these dynamics impact viral genetic variation. Transmission dynamics can be considered at the level of cells within an infected host, individual hosts within a population, or entire populations of hosts.Many viruses, especially RNA viruses, rapidly accumulate genetic variation because of short generation times and high mutation rates.Patterns of viral genetic variation are therefore heavily influenced by how quickly transmission occurs and by which entities transmit to one another.Patterns of viral genetic variation will also be affected by selection acting on viral phenotypes.Although viruses can differ with respect to many phenotypes, phylodynamic studies have to date tended to focus on a limited number of viral phenotypes.These include virulence phenotypes, phenotypes associated with viral transmissibility, cell or tissue tropism phenotypes, and antigenic phenotypes that can facilitate escape from host immunity.Due to the impact that transmission dynamics and selection can have on viral genetic variation, viral phylogenies can therefore be used to investigate important epidemiological, immunological, and evolutionary processes, such as epidemic spread, spatio-temporal dynamics including metapopulation dynamics, zoonotic transmission, tissue tropism, and antigenic drift.The quantitative investigation of these processes through the consideration of viral phylogenies is the central aim of viral phylodynamics.
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