Photo Album
... The first microtubule motor identified in nervous tissue was a kinesin 1, but studies in mammalian genomes identified 3 kinesin 1 genes, including a neuron-specific form (kinesin 1A). Motor domains are well conserved in all kinesin superfamily genes, but tail domains are more variable and only show ...
... The first microtubule motor identified in nervous tissue was a kinesin 1, but studies in mammalian genomes identified 3 kinesin 1 genes, including a neuron-specific form (kinesin 1A). Motor domains are well conserved in all kinesin superfamily genes, but tail domains are more variable and only show ...
Abstract
... properties. Of all inorganic cofactors, transition metal ions play a unique role in proteins. Among all of the transition metal ions present in all domains of life, zinc (formally Zn(II)) is one of the most widespread, reflecting the utilization of Zn(II) by proteins for a wide variety of biological ...
... properties. Of all inorganic cofactors, transition metal ions play a unique role in proteins. Among all of the transition metal ions present in all domains of life, zinc (formally Zn(II)) is one of the most widespread, reflecting the utilization of Zn(II) by proteins for a wide variety of biological ...
Note packet
... Bio.4.2 Analyze the relationships between biochemical processes and energy use in the cell. Bio.4.2.1 Analyze photosynthesis and cellular respiration in terms of how energy is stored, released, and transferred within and between these systems. ...
... Bio.4.2 Analyze the relationships between biochemical processes and energy use in the cell. Bio.4.2.1 Analyze photosynthesis and cellular respiration in terms of how energy is stored, released, and transferred within and between these systems. ...
Brookfield Academy Upper School SMART Team
... clotting. Major causes of homocystinuria are mutations in the enzyme cystathionine ß-synthase (CBS), which catalyzes the condensation of serine and homocysteine to cystathionine, an intermediate in cysteine synthesis. CBS is a pyridoxal 5’-phosphate (PLP) and heme dependent enzyme regulated by S-ade ...
... clotting. Major causes of homocystinuria are mutations in the enzyme cystathionine ß-synthase (CBS), which catalyzes the condensation of serine and homocysteine to cystathionine, an intermediate in cysteine synthesis. CBS is a pyridoxal 5’-phosphate (PLP) and heme dependent enzyme regulated by S-ade ...
Understanding Enzyme Mechanism through Protein Chimeragenesis
... and complexity, including small units of approximately ten to 30 amino acids, folded functional units, and large domains of several hundred amino acids that may have enzymatic activity (Ostermeier and Benkovic 2001). There are several types of hybrids. Single crossover hybrids consist of the N-termi ...
... and complexity, including small units of approximately ten to 30 amino acids, folded functional units, and large domains of several hundred amino acids that may have enzymatic activity (Ostermeier and Benkovic 2001). There are several types of hybrids. Single crossover hybrids consist of the N-termi ...
File 03
... it prevenst closing of hundred chanels and entering 105 to 107 Na+ /s to the cell Termination of the light response GTPase activity of a-GTP transducin converts it to a-GDP transducin opsin kinase adds ~ 9 phosphate groups to ...
... it prevenst closing of hundred chanels and entering 105 to 107 Na+ /s to the cell Termination of the light response GTPase activity of a-GTP transducin converts it to a-GDP transducin opsin kinase adds ~ 9 phosphate groups to ...
The WHy domain mediates the response to
... Kumar,S., Tamura,K., Jakobsen,I.B. and Nei,M. (2001) MEGA2: molecular evolutionary genetics analysis software. Bioinformatics, 17, 1244–1245. Letunic,I., Copley,R.R., Schmidt,S., Ciccarelli,F.D., Doerks,T., Schultz,J., Ponting,C.P. and Bork,P. (2004) SMART 4.0: towards genomic data integration. Nucl ...
... Kumar,S., Tamura,K., Jakobsen,I.B. and Nei,M. (2001) MEGA2: molecular evolutionary genetics analysis software. Bioinformatics, 17, 1244–1245. Letunic,I., Copley,R.R., Schmidt,S., Ciccarelli,F.D., Doerks,T., Schultz,J., Ponting,C.P. and Bork,P. (2004) SMART 4.0: towards genomic data integration. Nucl ...
ATP - BIOLUMINESCENCE
... ATP - BIOLUMINESCENCE • When ATP is present the enzyme - substrate complex is oxidised to an electronically excited state and releases a photon of light which can be measured in a photometer. Some living organisms, such as the firefly can produce light by this activity. • Very sensitive - can detec ...
... ATP - BIOLUMINESCENCE • When ATP is present the enzyme - substrate complex is oxidised to an electronically excited state and releases a photon of light which can be measured in a photometer. Some living organisms, such as the firefly can produce light by this activity. • Very sensitive - can detec ...
Biochemical screen for potential membrane fission catalysts
... thermodynamically unfavorable event, which according to previous literature is catalyzed by specific proteins that hydrolyze nucleotides. Apart from the large GTPase dynamin, which mediates membrane fission at the plasma membrane, little is known about the identity of catalysts engaged in generating ...
... thermodynamically unfavorable event, which according to previous literature is catalyzed by specific proteins that hydrolyze nucleotides. Apart from the large GTPase dynamin, which mediates membrane fission at the plasma membrane, little is known about the identity of catalysts engaged in generating ...
The exocyst, an octameric protein complex conserved among all
... The exocyst, an octameric protein complex conserved among all eukaryotes, mediates tethering of the vesicle prior to its fusion with the target membrane. Apart from the function of exocyst in exocytosis, new studies from both mammalian and plant fields report its involvement in the cellular self-eat ...
... The exocyst, an octameric protein complex conserved among all eukaryotes, mediates tethering of the vesicle prior to its fusion with the target membrane. Apart from the function of exocyst in exocytosis, new studies from both mammalian and plant fields report its involvement in the cellular self-eat ...
Passive and active transport
... pump K+ into the cell across the membrane and this needs a highly active glycolytic pathway to provide ATP needed to this transport. When we add fluoride which inhibits glycolysis, the intracellular conc of K+ will decrease and Na+ will rise. ...
... pump K+ into the cell across the membrane and this needs a highly active glycolytic pathway to provide ATP needed to this transport. When we add fluoride which inhibits glycolysis, the intracellular conc of K+ will decrease and Na+ will rise. ...
Poster - Protein Information Resource
... framework. Expert manual curation includes membership, annotation of specific biological functions, biochemical activities, and sequence features. Novel functional predictions for uncharacterized “hypothetical” proteins and protein families are routinely made in the annotation process. Fully curated ...
... framework. Expert manual curation includes membership, annotation of specific biological functions, biochemical activities, and sequence features. Novel functional predictions for uncharacterized “hypothetical” proteins and protein families are routinely made in the annotation process. Fully curated ...
5. Membrane Transporters
... proton and calcium pumps are oriented to pump these ions out of the cytoplasm. Inside mitochondria is a very special proton pump (the F1-ATPase, or ATP synthase) that, when running backwards, lets protons leak across a membrane and synthesizes, rather than hydrolyzes ATP. Secondary active transport ...
... proton and calcium pumps are oriented to pump these ions out of the cytoplasm. Inside mitochondria is a very special proton pump (the F1-ATPase, or ATP synthase) that, when running backwards, lets protons leak across a membrane and synthesizes, rather than hydrolyzes ATP. Secondary active transport ...
domain alignments - Oxford Academic
... link and expanding the summary to show more details will produce a graphical display, as shown in Figure 1. While the protein maps to a conserved family of unknown function (DUF135/pfam02003), the sequence also produces hits to two models for DNA ligases (pfam01068 and LOAD_ligase). In fact these th ...
... link and expanding the summary to show more details will produce a graphical display, as shown in Figure 1. While the protein maps to a conserved family of unknown function (DUF135/pfam02003), the sequence also produces hits to two models for DNA ligases (pfam01068 and LOAD_ligase). In fact these th ...
The ATP-Cone: An Evolutionarily Mobile, ATP
... Allosteric regulation is a common mechanism by which the activity of enzymes is modulated by the concentrations of their products, substrates and other small regulatory molecules. Structural studies have suggested that these functions frequently reside in compact globular domains that are distinct f ...
... Allosteric regulation is a common mechanism by which the activity of enzymes is modulated by the concentrations of their products, substrates and other small regulatory molecules. Structural studies have suggested that these functions frequently reside in compact globular domains that are distinct f ...
Building the Tree of Life
... Genetic analysis has revealed that the two main prokaryotic kingdoms are more different from each other, and from eukaryotes, than previously thought. So, biologists established a new taxonomic category—the domain. A domain is a larger, more inclusive category than a kingdom. Under this system, ther ...
... Genetic analysis has revealed that the two main prokaryotic kingdoms are more different from each other, and from eukaryotes, than previously thought. So, biologists established a new taxonomic category—the domain. A domain is a larger, more inclusive category than a kingdom. Under this system, ther ...
Plantae - Stotts 5th Biology
... The kingdom Protista is composed of eukaryotic organisms that cannot be classified as animals, plants, or fungi. Its members display the greatest variety. They can be unicellular or multicellular; photosynthetic or heterotrophic; and can share characteristics with plants, fungi, or animals. ...
... The kingdom Protista is composed of eukaryotic organisms that cannot be classified as animals, plants, or fungi. Its members display the greatest variety. They can be unicellular or multicellular; photosynthetic or heterotrophic; and can share characteristics with plants, fungi, or animals. ...
Photosynthesis in nature - Ms. Pass's Biology Web Page
... Calvin Cycle, net synthesis • For each G3P (and for 3 CO2)……. Consumption of 9 ATP’s & 6 NADPH (light reactions regenerate these molecules) • G3P can then be used by the plant to make glucose and other organic compounds ...
... Calvin Cycle, net synthesis • For each G3P (and for 3 CO2)……. Consumption of 9 ATP’s & 6 NADPH (light reactions regenerate these molecules) • G3P can then be used by the plant to make glucose and other organic compounds ...
Aim: Why are Enzymes necessary for our survival?
... Substrates-are the substances that bind to the enzyme Active Site- is the place on the enzyme where the ...
... Substrates-are the substances that bind to the enzyme Active Site- is the place on the enzyme where the ...
03b_TransportMechanisms
... • Facilitated diffusion (no ATP required because movement is down concentration gradient (“downhill”) • Active Transport (ATP required) • Molecules move against concentration gradient (“uphill”) • Ion pumps (e.g., Na-K pump) ...
... • Facilitated diffusion (no ATP required because movement is down concentration gradient (“downhill”) • Active Transport (ATP required) • Molecules move against concentration gradient (“uphill”) • Ion pumps (e.g., Na-K pump) ...
chapter 5 tranportB
... transport occur? • Glucose absorption in the intestine • Glucose absorption in the nephron • Glucose is moved from the mucosal surface of the epithelium to the serosal ...
... transport occur? • Glucose absorption in the intestine • Glucose absorption in the nephron • Glucose is moved from the mucosal surface of the epithelium to the serosal ...
How Enzymes Work
... to accelerate the rate of a chemical reaction by held to have an important role in catalysis, but their catalytic power from varying combinastaggering amounts—up to 1020 times the rate other details were murky. tions of these simple factors. Confirming eviof the uncatalyzed reaction in water (3)—whi ...
... to accelerate the rate of a chemical reaction by held to have an important role in catalysis, but their catalytic power from varying combinastaggering amounts—up to 1020 times the rate other details were murky. tions of these simple factors. Confirming eviof the uncatalyzed reaction in water (3)—whi ...
Origin of Life Reading Guide
... Origin of Life 1. What are the three most common shapes of prokaryotes – their formal and “common” name? 2. What is the cell wall made of and how does that relate to the concept that some bacteria are identified as Gram Positive and some Gram Negative? ...
... Origin of Life 1. What are the three most common shapes of prokaryotes – their formal and “common” name? 2. What is the cell wall made of and how does that relate to the concept that some bacteria are identified as Gram Positive and some Gram Negative? ...
SB-431542: Potent and selective inhibitor of activin receptor
... affinity site of H+,K+-ATPase. In contrast, SCH-28080 does not inhibit Na+,K+-ATPase. In addition, SCH-28080 inhibits renal ouabain-insensitive H+,K+-ATPase, but not colonic ouabain-sensitive H+,K+-ATPase [2]. The inhibition of ATPase activity by ouabain (Prod. No. O 3125) has been widely used as a ...
... affinity site of H+,K+-ATPase. In contrast, SCH-28080 does not inhibit Na+,K+-ATPase. In addition, SCH-28080 inhibits renal ouabain-insensitive H+,K+-ATPase, but not colonic ouabain-sensitive H+,K+-ATPase [2]. The inhibition of ATPase activity by ouabain (Prod. No. O 3125) has been widely used as a ...
P-type ATPase
The P-type ATPases, also known as E1-E2 ATPases, are a large group of evolutionarily related ion and lipid pumps that are found in bacteria, archaea, and eukaryotes. They are α-helical bundle primary transporters referred to as P-type ATPases because they catalyze auto- (or self-) phosphorylation of a key conserved aspartate residue within the pump. In addition, they all appear to interconvert between at least two different conformations, denoted by E1 and E2.Most members of this transporter family are specific for the pumping of a large array of cations, however one subfamily is involved in flipping phospholipids to maintain the asymmetric nature of the biomembrane.Prominent examples of P-type ATPases are the sodium-potassium pump (Na+,K+-ATPase), the plasma membrane proton pump (H+-ATPase), the proton-potassium pump (H+,K+-ATPase), and the calcium pump (Ca2+-ATPase).