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Screening for prostate cancer
Screening for prostate cancer

... symptoms are not at increased risk of prostate cancer. The rate of registration of prostate cancer has been steadily rising. This is probably due to the ageing of the population, increased diagnostic accuracy and recording of cases, and increased detection due to more frequent surgery for BPH. Most ...
Management and Survival of Screen
Management and Survival of Screen

... Screening has caused a marked increase in prostate cancer incidence, although whether the stage and grade shift that has been caused by prostate-specific antigen (PSA)-based screening reduces the prostate cancer mortality is unclear. In the United States, it is estimated that 234,460 men will be dia ...
XML - UBC Library
XML - UBC Library

... Population screening has been incorporated into multiple disease management strategies. Despite prostate cancer screening programs being in place for almost two decades, their effectiveness in reducing mortality continues to be contentiously debated, resulting in polarized recommendations by various ...
docx - UBC Library
docx - UBC Library

... Population screening has been incorporated into multiple disease management strategies. Despite prostate cancer screening programs being in place for almost two decades, their effectiveness in reducing mortality continues to be contentiously debated, resulting in polarized recommendations by various ...
PSA Testing - PROSTAID Calgary
PSA Testing - PROSTAID Calgary

...  While the PSA test may not be the ‘perfect’ test, it is a valuable tool as part of ‘smart’ screening  and risk assessment (McDonald and Parsons 2015),    The PSA test for risk assessment is most useful when the test is repeated over several years  starting when a man is 40 or older. The trend of  ...
The process of developing National Guidelines supports
The process of developing National Guidelines supports

... National Guidelines for Breast, Colorectal and Prostate Cancer An example of updating a guideline • Project started fall 2010 • Scientific foundation during 2011 • Prioritizing during 2012 • Preliminary version 2013 (6th of March) • National and regional conferences spring 2013 • Final version 2013/ ...
Summary - Cancer Care Ontario
Summary - Cancer Care Ontario

... All recommended wait times were based on consensus of the Working Group. The Canadian Association of Radiation Oncology recommended a wait time from referral to consultation with a radiation oncologist of no longer than 10 working days (6). This was taken into consideration when developing the wait ...
Currently one of the limiting factors in the clinical acceptance of
Currently one of the limiting factors in the clinical acceptance of

Speaker key - Camden GP Website
Speaker key - Camden GP Website

... Most men with prostate cancer don’t really have any symptoms directly related to the tumour. They only have symptoms, in fact, if the tumour is very widely spread and metastatic. So in this day and age with the PSA, prostate specific antigen blood test, most men will present with a high PSA. With re ...
Local Prostate Cancer - Alberta Health Services
Local Prostate Cancer - Alberta Health Services

... or worsening biopsy characteristics (e.g. Gleason grade and or/volume changes) ii. The patient may choose to proceed with curative therapy due to personal preference at any time. iii. Curative intervention may be required later and patients may be candidates for clinical trials. iv. Patients with lo ...
Differentiation of prostate cancer and benign prostatic hyperplasia
Differentiation of prostate cancer and benign prostatic hyperplasia

... imaging method because of poor imaging characteristics, with poor imaging energies and a long physical and biologic half-life. However, the recent use of SPECT has improved the depiction and resolution of 201Tl in detection of lesions compared to conventional planar image.26 In the results of this s ...
PROSTATE CANCER - Resolution Health
PROSTATE CANCER - Resolution Health

... Studies show that a diet high in dairy products and calcium may be linked to an increased risk of prostate cancer, although the increase may be small. Hormonal prevention: Studies are underway to discover the role of certain drugs, such as finasteride, that reduce the amount of male hormone as preve ...
in-kind donation form - Urology Center of Colorado
in-kind donation form - Urology Center of Colorado

... I am walking [Insert motivation (*see below for examples)]. It is estimated that more than 192,000 American men will be diagnosed with prostate cancer this year, with one case occurring every 2.7 minutes. More than 3,000 Colorado men are diagnosed with the disease every year. Prostate cancer will to ...
Digital Microscopy Evaluation of Cellular proliferation
Digital Microscopy Evaluation of Cellular proliferation

... heterogeneous across samples and did not vary with Gleason score in this cohort. Interestingly, the MIB1/CD31 ratio was significantly increased in high (≥ 8) versus low/intermediate (≤7) samples when assessed in the training set as well as the whole slide images. Discussion: This work establishes a ...
The post PSA era: new developments in biomarkers, imaging and
The post PSA era: new developments in biomarkers, imaging and

Blood-based gene expression profiling in castrate-resistant prostate cancer Open Access
Blood-based gene expression profiling in castrate-resistant prostate cancer Open Access

... Genes representing the greatest differences in expression levels between good and poor risk groups were used to develop a prognostic model using a Bayesian learning algorithm. A four-gene model incorporating MCM2, PROS1, CD22, and TMEM66 performed best in crossvalidation tests and was selected for f ...
Validity of Digital Rectal Examination in the Era of Prostate
Validity of Digital Rectal Examination in the Era of Prostate

... From the total patients studied (n=706), the presence of cancer was detected in 199 cases (28.2%). The distribution of total PSA values and the findings of DRE are shown in Table 1. 61.0% of the sample (431/706) had a PSA value between 4 ng/mL and 10 ng/mL. The DRE was suggestive of being benign in ...
Questions to Ask My Doctor About Prostate Cancer
Questions to Ask My Doctor About Prostate Cancer

... These questions are grouped by where you are in the process of cancer treatment. Not all of the questions will apply to you, but they should help get you started. For information on prostate cancer please contact your American Cancer Society toll free at 1-800227-2345 or online at www.cancer.org. ...
Prostate Cancer Studies
Prostate Cancer Studies

... Phase III study of TAK-700 plus prednisone for patients with advanced prostate cancer who have not yet received treatment with chemotherapy Recruiting Study information link: http://elmpctrials.com/ ...
Prostate cancer prevention - Canadian Urological Association
Prostate cancer prevention - Canadian Urological Association

... cancer. Certain races and ethnic groups are also at increased risk for developing prostate cancer (e.g. men of African descent). Generally, the risk of prostate cancer is increased as a man ages (>55 years of age). ...
Text - Ulster Institutional Repository
Text - Ulster Institutional Repository

... Studies in the early 1990s confirmed that serum PSA levels could be used to identify patients with prostate cancer [16, 32, 33]. The serum PSA is the most commonly used tumour biomarker for PCa and has a relevant role, despite possessing some considerable limitations in the detection, staging and p ...
December 26, 2004
December 26, 2004

... • The benefits of one-time or repeated screening and aggressive treatment of prostate cancer have not yet been proven. • Digital rectal examinations and PSA measurements can have both false-positive and false-negative results. • The probability that further invasive evaluation will be required as a ...
April 2014 - the website of Nottingham Prostate Cancer Support
April 2014 - the website of Nottingham Prostate Cancer Support

... early diagnosis and treatment of cancer. State-of-the-art technology platforms are focused on two key areas:  To improve the diagnosis and management of prostate cancer  To develop effective vaccines and immunotherapies that will significantly improve survival rates and quality of life” “We have i ...
Private Cancer - Wayne State University
Private Cancer - Wayne State University

... cancer is false? – A) Among gynecologic cancers it is the most common cause of death – B) Typically presents as advanced disease – C) Tubal ligation is associated with decreased risk for ovarian cancer – D) Surgery is necessary for accurate staging – E) Elevated serum CA-125 is specific for ovarian ...
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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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