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video slide - Wild about Bio
video slide - Wild about Bio

... Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings ...
Mitochondrial DNA and aging
Mitochondrial DNA and aging

... particular, in mtDNA, is ubiquitous, substantial and, like mortality rates, increases exponentially with age [35] It has been shown that exhalation of ethane and n-penthane, indicators of ROS-mediated lipid peroxidation increases with age [36]. mtDNA was shown to accumulate oxidative damage in an ag ...
How Cells Obtain Energy from Food - Molecular Biology of the Cell
How Cells Obtain Energy from Food - Molecular Biology of the Cell

... produced—ATP and NADH. The pyruvate then passes from the cytosol into mitochondria. There, each pyruvate molecule is converted into CO 2 plus a two-carbon acetyl group—which becomes attached to coenzyme A (CoA), forming acetyl CoA, another activated carrier molecule (see Figure 2-62). Large amounts ...
The Proton-Motive Force Overview Compartmentalization
The Proton-Motive Force Overview Compartmentalization

... process – Battery connected  to wire ...


... Choice A: The aldolase reaction in glycolysis converts fructose-1-6-P to glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. This reaction has a standard energy (∆Go) of +24 kJ/M, however during glycolysis the Gibbs free energy, ∆G, is –6 kJ/mol. i) Briefly describe why there is a large diffe ...
6. In both photosynthesis and respiration, a electrochemical proton
6. In both photosynthesis and respiration, a electrochemical proton

... 3. When electrons are transferred between molecules in a sequence of reactions as they pass through the ETC, an electrochemical gradient of hydrogen ions (protons) across the thykaloid membrane is established. 4. The formation of the proton gradient is a separate process, but it is linked to the syn ...
Microbial Metabolism
Microbial Metabolism

... Chemoorganoheterotroph Metabolism Overview: Reduction; e- gain from donor ...
5-Cell and Molecular Biology (Golgi etc)
5-Cell and Molecular Biology (Golgi etc)

... pressure in the face of large changes in the tonicity (it is a measure of the osmotic pressure gradient of two solutions separated by a semi permeable membrane) of the fluid in their immediate environment • They do so by changing the osmotic pressure of the cytosol and vacuole - in part by controlle ...
Ch18.doc
Ch18.doc

... 2. Note that the question says “excess of pure lactate dehydrogenase and NADH”. This is important because alanine-transaminase will produce pyruvate which as soon as it is produced will be reduced to lactic acid using NADH. NADH has a strong absorbance at 340 nm, so the rate of decrease in 340 nm ab ...
Respiration and Lipid Metabolism - Roberto Cezar | Fisiologista
Respiration and Lipid Metabolism - Roberto Cezar | Fisiologista

... (and nearly all other life) depend on. Respiration, with its associated carbon metabolism, releases the energy stored in carbon compounds in a controlled manner for cellular use. At the same time it generates many carbon precursors for biosynthesis. In the first part of this chapter we will review r ...
32. It is most reasonable to hypothesize that, in the
32. It is most reasonable to hypothesize that, in the

... 3. When electrons are transferred between molecules in a sequence of reactions as they pass through the ETC, an electrochemical gradient of hydrogen ions (protons) across the thykaloid membrane is established. 4. The formation of the proton gradient is a separate process, but it is linked to the syn ...
O - bio-brainstorm
O - bio-brainstorm

... Glycolysis is only the start  Glycolysis glucose      pyruvate 6C ...
BIOLOGY CH9PPTOL NAME______________________
BIOLOGY CH9PPTOL NAME______________________

... The cells of most organisms transfer energy found Proteins and nucleic acids can also be used to make in organic compounds, such as those in foods, to ATP, but they are usually used for building ATP. important cell parts. The primary fuel for cellular respiration is _____________. Q18 WHERE DO YOU G ...
Antifolding activity of hsp60 couples protein import into the
Antifolding activity of hsp60 couples protein import into the

... interaction between the pb2-DHFR fusion proteins and hsp60-14mer. The topology of mature-sized b2(331)DHFR arrested in contact sites in the presence of MTX was analyzed as a representative example (Figure 4). Upon removal of the MTX-stabilized DHFR moiety by protease treatment, the resulting cytochr ...
CARBOHYDRATE METABOLISM
CARBOHYDRATE METABOLISM

... Major pathways of carbohydrate metabolism 1. Glycolysis (Embden-Meyerhof pathway): The oxidation of glucose to pyruvate and lactate.(Located in cytosol) 2. Citric acid cycle (Krebs cycle or tricarboxylic acid cycle): The oxidation of acetyl CoA to CO2. Krebs cycle is the final common oxidative pathw ...
Slide 1
Slide 1

...  The energy necessary for life is contained in the arrangement of electrons in chemical bonds in organic molecules.  An important question is how do cells extract this ...
VI. Reaction Coupling and ATP
VI. Reaction Coupling and ATP

... Electron Transport Chain: Generalized Scheme 1. NADH and FADH2 pass electrons to an electron transport chain 2. Energy is released as electrons “fall” and lose energy 3. Energy is harvested as ATP ...
Photosynthesis Chloroplasts Light Reactions (photons → NADPH +
Photosynthesis Chloroplasts Light Reactions (photons → NADPH +

... Photosynthesis in C4 plants consumes 5 ATP per CO2 fixed (compare to 3 ATP for Calvin cycle alone) C4 plants occur largely in tropical areas (high temperatures and light intensity) C3 plants occur largely in cooler areas (lower light ...
Lipids (lect 4))
Lipids (lect 4))

... Acetyl CoA is the precursor of fatty acid synthesis. It is produced from oxidation of glucose (by oxidative decarboxylation of pyruvate), βoxidation of fatty acids and metabolism of ketogenic and mixed amino acids. Acetyl CoA is produced in mitochondria, and FA synthesis occurs in cytoplasm, so acet ...
File
File

... conditions yields ~30 ATP per glucose. • Anaerobic metabolism of glucose in tumor cells yields 2 ATP per glucose. – Glucose transporters and most glycolytic enzymes are overexpressed in tumors versus normal cells. – Inhibitors of glycolytic pathways could be effective anticancer drugs. ...
Microsoft Word
Microsoft Word

... Measurement of respiration and ATP synthesis/hydrolysis activities in whole mitochondria. For these assays, mitochondria were prepared by the enzymatic method of (Guerin et al., 1979). The rates of ATP synthesis were determined as described in (Rak et al., 2007a). For respiration ATP synthesis and t ...
Skeletal muscle phenotype affects fasting
Skeletal muscle phenotype affects fasting

... 2011; Teulier et al., 2013). In a recently published paper, it was shown that skeletal muscle mitochondria from fasted winteracclimatized chicks minimized the cost of ATP synthesis by increasing the efficiency of oxidative phosphorylation processes, which would ultimately alleviate the need for ener ...
micro notes chpt. 8
micro notes chpt. 8

... d. ATP and NADPH are fed into the stroma of the chloroplast and enter the Calvin cycle, eventually producing glucose. e. Oxygenic photosynthesis uses H2O as a source of electrons and produces oxygen as a byproduct. Anoxygenic photosynthesis employs a cyclic photosystem that uses H2 and H2S as a sour ...
File
File

... 7. Cellular respiration is described as a stepwise redox reaction. a. What substance is oxidized?____________________________________ b. What substance is reduced?____________________________________ ...
Honors Biology A 4W5 Respiration (divide by
Honors Biology A 4W5 Respiration (divide by

... formation of ATP is called ______________________________. is the enzyme that helps convert a 2 carbon molecule with a 4 carbon molecule to make citric acid. ______________________________ is the organelle that contains the enzymes for ...
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Mitochondrion



The mitochondrion (plural mitochondria) is a double membrane-bound organelle found in most eukaryotic cells. The word mitochondrion comes from the Greek μίτος, mitos, i.e. ""thread"", and χονδρίον, chondrion, i.e. ""granule"" or ""grain-like"".Mitochondria range from 0.5 to 1.0 μm in diameter. A considerable variation can be seen in the structure and size of this organelle. Unless specifically stained, they are not visible. These structures are described as ""the powerhouse of the cell"" because they generate most of the cell's supply of adenosine triphosphate (ATP), used as a source of chemical energy. In addition to supplying cellular energy, mitochondria are involved in other tasks, such as signaling, cellular differentiation, and cell death, as well as maintaining control of the cell cycle and cell growth. Mitochondria have been implicated in several human diseases, including mitochondrial disorders, cardiac dysfunction, and heart failure. A recent University of California study including ten children diagnosed with severe autism suggests that autism may be correlated with mitochondrial defects as well.Several characteristics make mitochondria unique. The number of mitochondria in a cell can vary widely by organism, tissue, and cell type. For instance, red blood cells have no mitochondria, whereas liver cells can have more than 2000. The organelle is composed of compartments that carry out specialized functions. These compartments or regions include the outer membrane, the intermembrane space, the inner membrane, and the cristae and matrix. Mitochondrial proteins vary depending on the tissue and the species. In humans, 615 distinct types of protein have been identified from cardiac mitochondria, whereas in rats, 940 proteins have been reported. The mitochondrial proteome is thought to be dynamically regulated. Although most of a cell's DNA is contained in the cell nucleus, the mitochondrion has its own independent genome. Further, its DNA shows substantial similarity to bacterial genomes.
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