Enzymatic properties of the N- and C
... as determined by SDS–PAGE and western blotting (Supplemental Material 1). We first investigated the enzymatic activity of each purified HK II deletion mutant. As shown in Table 1, expression of HK II, N-term, and C-term was associated with glucose phosphorylating activity. Interestingly, the enzyme ...
... as determined by SDS–PAGE and western blotting (Supplemental Material 1). We first investigated the enzymatic activity of each purified HK II deletion mutant. As shown in Table 1, expression of HK II, N-term, and C-term was associated with glucose phosphorylating activity. Interestingly, the enzyme ...
CELLULAR RESPIRATION 04 JUNE 2014 Lesson Description
... A mitochondrion has two membranes – an inner and an outer membrane. Between the membranes is a space. The inner membrane is folded and these folds are called cristae and the space in the centre of the inner membrane is called the matrix. The cristae increase the surface area of the inner membrane an ...
... A mitochondrion has two membranes – an inner and an outer membrane. Between the membranes is a space. The inner membrane is folded and these folds are called cristae and the space in the centre of the inner membrane is called the matrix. The cristae increase the surface area of the inner membrane an ...
Chp 5 Macromolecules
... 6. Identify a glycosidic linkage and describe how it is formed. 7. Describe the important biological functions of polysaccharides. 8. Distinguish between the glycosidic linkages found in starch and cellulose, and explain why the difference is biologically important. 9. Explain what distinguishes lip ...
... 6. Identify a glycosidic linkage and describe how it is formed. 7. Describe the important biological functions of polysaccharides. 8. Distinguish between the glycosidic linkages found in starch and cellulose, and explain why the difference is biologically important. 9. Explain what distinguishes lip ...
Glycolysis
... Glucose metabolism begins with transfer of a phosphate from ATP to glucose to form glucose6-P. This step is notable for two reasons: (1) glucose 6-phosphate cannot diffuse through the membrane, because of its negative charges, and (2) the addition of the phosphoryl group begins to destabilize glucos ...
... Glucose metabolism begins with transfer of a phosphate from ATP to glucose to form glucose6-P. This step is notable for two reasons: (1) glucose 6-phosphate cannot diffuse through the membrane, because of its negative charges, and (2) the addition of the phosphoryl group begins to destabilize glucos ...
Site directed mutagenesis of Drosophila flightin disrupts
... (Kronert et al. 1995), indicate that the myosin rod represents the primary binding site for flightin in the sarcomere. A recent study (Flashman et al. 2007) has shown that the CX myosin binding domain of vertebrate myosin binding protein C (MyBP-C) binds to the light meromyosin (LMM) region between ...
... (Kronert et al. 1995), indicate that the myosin rod represents the primary binding site for flightin in the sarcomere. A recent study (Flashman et al. 2007) has shown that the CX myosin binding domain of vertebrate myosin binding protein C (MyBP-C) binds to the light meromyosin (LMM) region between ...
Chromatin Remodeling and Gene Expression
... incorporated in the actively transcribed phas chromatin with the loss of histone H4-K20 dimethylation. During active phas transcription, histone displacement and redeposition of variant histones may take place that result in the deposition of new histone modifications at the phas chromatin. Although ...
... incorporated in the actively transcribed phas chromatin with the loss of histone H4-K20 dimethylation. During active phas transcription, histone displacement and redeposition of variant histones may take place that result in the deposition of new histone modifications at the phas chromatin. Although ...
Carbohydrate Metabolism Synopsis of Glycolytic Enzyme Deficiencies
... *Stars indicate key controlling enzymes and steps of glycolysis. The light-color star connecting pyruvate to acetyl CoA is not a glycolytic step. It marks the pyruvate dehydrogenase enzyme (PDH) that is required for aerobic respiration of glucose. ...
... *Stars indicate key controlling enzymes and steps of glycolysis. The light-color star connecting pyruvate to acetyl CoA is not a glycolytic step. It marks the pyruvate dehydrogenase enzyme (PDH) that is required for aerobic respiration of glucose. ...
Respiration and Metabolism
... Picture from http://www.dtc.ucsf.edu/type2/health-management/diet-and-nutrition/your-blood-lipids.html Designed by Pyeongsug Kim, ©2010 www.science-i.com ...
... Picture from http://www.dtc.ucsf.edu/type2/health-management/diet-and-nutrition/your-blood-lipids.html Designed by Pyeongsug Kim, ©2010 www.science-i.com ...
biochemichistry of the eye
... METABOLIC PATHWAYS IN EYE TISSUE • Glycolysis ( aerobic & anaerobic) • HMP shunt • Poliol pathway • TCA cycle ...
... METABOLIC PATHWAYS IN EYE TISSUE • Glycolysis ( aerobic & anaerobic) • HMP shunt • Poliol pathway • TCA cycle ...
Cellular Respiration - Chandler Unified School District
... If the main purpose of cell respiration is to produce ATP, why do glycolysis & the Krebs cycle only make 4 molecules of ATP total by the time glucose has been converted to carbon dioxide? Although glycolysis & the Krebs cycle only produce 4 ATP molecules when glucose is converted to CO2 , these rea ...
... If the main purpose of cell respiration is to produce ATP, why do glycolysis & the Krebs cycle only make 4 molecules of ATP total by the time glucose has been converted to carbon dioxide? Although glycolysis & the Krebs cycle only produce 4 ATP molecules when glucose is converted to CO2 , these rea ...
This is an author produced version of a paper
... In this work, using a number of cAMP modulating agents and other chemical tools as well as overexpression strategies, we show that insulin and cAMP signalling pathways interact to control PKB phosphorylation (at Ser473/4 in PKB α and β, respectively) and thereby activation in adipocytes. Furthermor ...
... In this work, using a number of cAMP modulating agents and other chemical tools as well as overexpression strategies, we show that insulin and cAMP signalling pathways interact to control PKB phosphorylation (at Ser473/4 in PKB α and β, respectively) and thereby activation in adipocytes. Furthermor ...
Document
... • TOR pathway is a major integrator of nutrient-derived signals in cell growth • TOR = Target of Rapamycin, originally identified by mutations in yeast that confer resistance to rapamycin ...
... • TOR pathway is a major integrator of nutrient-derived signals in cell growth • TOR = Target of Rapamycin, originally identified by mutations in yeast that confer resistance to rapamycin ...
Document
... Answer: After infection, the key protein affected by cellular proteases is cII. If protease levels are high, as under good growth conditions, cII is degraded. This promotes the lytic cycle. Under starvation conditions, the protease levels are low. This prevents the degradation of cII and thereby pro ...
... Answer: After infection, the key protein affected by cellular proteases is cII. If protease levels are high, as under good growth conditions, cII is degraded. This promotes the lytic cycle. Under starvation conditions, the protease levels are low. This prevents the degradation of cII and thereby pro ...
S1.Researchers have identified mutations in the promoter region of
... Answer: After infection, the key protein affected by cellular proteases is cII. If protease levels are high, as under good growth conditions, cII is degraded. This promotes the lytic cycle. Under starvation conditions, the protease levels are low. This prevents the degradation of cII and thereby pro ...
... Answer: After infection, the key protein affected by cellular proteases is cII. If protease levels are high, as under good growth conditions, cII is degraded. This promotes the lytic cycle. Under starvation conditions, the protease levels are low. This prevents the degradation of cII and thereby pro ...
Title New tricks for KDEL receptors Author(s)
... produced the expected opposite effect. These observations correlated with the presence of phosphorylated Src in the regions overlapping ECM degradation patches. KDLER stimulation led to tyrosine phosphorylation of ASAP1, a known Src effector, and experimental manipulations leading to either activati ...
... produced the expected opposite effect. These observations correlated with the presence of phosphorylated Src in the regions overlapping ECM degradation patches. KDLER stimulation led to tyrosine phosphorylation of ASAP1, a known Src effector, and experimental manipulations leading to either activati ...
C6H12O6 + 6 O2* 6 CO2 + 6H2O + 38 ATP
... 1 Glucose (2 pyruvates) goes through 2 Citric Acid Cycles ...
... 1 Glucose (2 pyruvates) goes through 2 Citric Acid Cycles ...
doc BIOC 311 Final Study Guide
... 2.) GLUT-2 – found in the liver and pancreatic beta cells. Low affinity, high capacity 'glucose sensor'. 3.) Glut-4 – skeletal and cardiac muscle. Insulin-responsive glucose transporter that tells cells to take up glucose. C. The Glycolytic Pathway Reactions: 1. Glucose + ATP → Glucose-6-Phosphate* ...
... 2.) GLUT-2 – found in the liver and pancreatic beta cells. Low affinity, high capacity 'glucose sensor'. 3.) Glut-4 – skeletal and cardiac muscle. Insulin-responsive glucose transporter that tells cells to take up glucose. C. The Glycolytic Pathway Reactions: 1. Glucose + ATP → Glucose-6-Phosphate* ...
Protein
... plasma membrane, where the enzyme catalyzes the phophorylation of PIP2 to PIP3. PIP3 acts as a second messenger, carrying the message from extracellular insulin to certain intracellular protein kinases. Recent research has found that many of the effects of insulin on cells are mediated through PIP2. ...
... plasma membrane, where the enzyme catalyzes the phophorylation of PIP2 to PIP3. PIP3 acts as a second messenger, carrying the message from extracellular insulin to certain intracellular protein kinases. Recent research has found that many of the effects of insulin on cells are mediated through PIP2. ...
Lec 3: Carbohydrate metabolism
... during muscle exertion is transported to the liver, for resynthesis of glucose by gluconeogenesis. • Transport of glucose back to muscle for synthesis of glycogen, and its reutilization in glycolysis, completes the ...
... during muscle exertion is transported to the liver, for resynthesis of glucose by gluconeogenesis. • Transport of glucose back to muscle for synthesis of glycogen, and its reutilization in glycolysis, completes the ...
Enzymes: Regulation 1
... 5 principal ways protein/enzyme activity is regulated 1. Allosteric control • Regulate binding affinity for ligands, and/or of catalytic activity, by conformational changes caused by binding of the same or other ligands at other sites on protein ("allosteric effects") • Changes involve simple associ ...
... 5 principal ways protein/enzyme activity is regulated 1. Allosteric control • Regulate binding affinity for ligands, and/or of catalytic activity, by conformational changes caused by binding of the same or other ligands at other sites on protein ("allosteric effects") • Changes involve simple associ ...
Cellular Respiration
... Have energy between phosphate bonds ATP supplies energy by breaking the bonds between phosphates Energy is used to carry out chemical reactions The bonds are restored by respiration ...
... Have energy between phosphate bonds ATP supplies energy by breaking the bonds between phosphates Energy is used to carry out chemical reactions The bonds are restored by respiration ...
glucose
... • Glucose-1-phosphate can be converted to glucose-6phosphate, which can enter glycolysis • Phosphorylated glucose can’t be absorbed into cells - in the liver and kidneys, glucose-6-phosphate can be hydrolized to glucose • Glycogenolysis is activated by glucogon in the liver and epinephrine in muscle ...
... • Glucose-1-phosphate can be converted to glucose-6phosphate, which can enter glycolysis • Phosphorylated glucose can’t be absorbed into cells - in the liver and kidneys, glucose-6-phosphate can be hydrolized to glucose • Glycogenolysis is activated by glucogon in the liver and epinephrine in muscle ...
Phosphorylation
Phosphorylation is the addition of a phosphate (PO43−) group to a protein or other organic molecule. Phosphorylation and its counterpart, dephosphorylation, turn many protein enzymes on and off, thereby altering their function and activity. Protein phosphorylation is one type of post-translational modification.Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2015, the Medline database returns over 240,000 articles on the subject, largely on protein phosphorylation).