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AMPK and mTOR: Antagonist ATP Sensors
AMPK and mTOR: Antagonist ATP Sensors

... ATP decreases, which works antagonistically to mTOR). The main energy-consuming process in a cell is protein synthesis. When mTOR is activated (high ATP levels sensed) protein synthesis is increased and when mTOR is suppressed (low ATP levels are sensed) protein synthesis is blunted. mTOR activation ...
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File

... After about 3 days of starvation, the liver forms large amounts of acetoacetate and β-hydroxybutyrate (ketone bodies). Their synthesis from acetyl CoA increases markedly because the citric acid cycle is unable to oxidize all the acetyl units generated by the degradation of fatty acids. Gluconeogenes ...
Problem-Set Solutions
Problem-Set Solutions

... phosphoenolpyruvate, can also act as an intermediate in the first step of the citric acid cycle; oxaloacetate combines with acetyl CoA, which can go directly into the citric acid cycle. 24.70 GTP and ATP 24.71 Lactate formed by muscle activity diffuses into the blood and is carried to the liver wher ...
AP Biology Ch. 9 Cellular Respiration
AP Biology Ch. 9 Cellular Respiration

... without oxygen. It only releases a small amount of ATP. Glycolysis: the first step of breaking down glucose—it splits glucose (6C) into 2 pyruvic acid molecules (3C each) ...
PPT slides - USD Biology
PPT slides - USD Biology

... – Main stores of glycogen in the body are in the liver, but stores are also present in the heart and in skeletal muscle. – Skeletal muscle stores important for burst activity. ...
BIOL 103 Ch5-2 for Students
BIOL 103 Ch5-2 for Students

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Regulation of plasmodesmal transport by phosphorylation of
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... 1997; Rhee et al., 2000; Tz®ra et al., 2000). Potentially, MP activity within infected cells may be negatively regulated to prevent its continuous interference with the host plant intercellular communication. The molecular mechanism by which such regulation may occur is unknown. Here, we address thi ...
Ketamalt® 50
Ketamalt® 50

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... transfer that mediates host transcriptional regulation. Signal transduction through Mitogen Activated Protein Kinase (MAPK) cascades constitutes another prominent example where multiple kinases are successively phosphorylated that ultimately leads to transcriptional activation involving a phosphoryl ...
Cellular Respiration
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Cell Respiration
Cell Respiration

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Mock Exam 1 Chapters 1 – 7 Anthony Todd  http
Mock Exam 1 Chapters 1 – 7 Anthony Todd http

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Cellular Respiration
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... Phosphofructokinase (catalyzes step 3 of Glycolysis) controls C.R.  It is activated by ADP and inhibited by ATP  NADH inhibits pyruvate decarboxylase and prevents Acetyl-CoA from forming  An organism’s Metabolic Rate is the amount of energy consumed by an organism in a given time. ...
Cell Respiration
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Cellular respiration occurs in three stages
Cellular respiration occurs in three stages

... in the presence of oxygen, the two pyruvate molecules produced by glycolysis travel to mitochondria  Krebs Cycle has 8 steps, each step is catalyzed by a different enzyme  Each cycling requires the input of 2-carbon acetyl-CoA and two carbons are released as C02  glycolysis results in the product ...
Signal Transduction Pathways • Signal Transduction
Signal Transduction Pathways • Signal Transduction

... triggers smooth muscle contraction, glycogen breakdown, and vesicle release Calcium is also a signal molecule: it can bind proteins called calmodulin and enzymes such as protein kinase C ...
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Chapter 9 review sheet
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... phosphofructokinase, G3P, FAD, FADH2, glycolysis, glucose, cytosol, inner mitochondrial membrane, outer mitochondrial membrane, preparatory phase, energy payoff phase, intermembrane space, ATP synthase, oxygen, hydrolysed, ATP, ADP, Pi, H+(protons), electrochemical gradient, cristae, Coenzyme A, pyr ...
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BCHM 463 Supplemental Problems for Friday, April 2, 2004 1. Write
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... Rxn 3: phosphofructo kinase: ATP is an allosteric inhibitor; AMP, ADP, F2,6P, and other compounds overcome this inhibition and therefore serve as activators Rxn 10: pyruvate kinase: product inhibition by ATP (allosteric); FBP acts as an allosteric activator 11. Xylose has the same structure as gluco ...
2. tissue - specific metabolism - cmb
2. tissue - specific metabolism - cmb

... When glucose levels are adequate, the production of dihydroxyacetone phosphate generates enough glycerol-3-phosphate for the resynthesis of triacylglycerols from the released fatty acids. When intracellular glucose levels fall, the concentration of glycerol-3-phosphate falls also, and fatty acids ar ...
Structural biology reveals links between Inflammation and Metabolic
Structural biology reveals links between Inflammation and Metabolic

... 1. To characterize the binding properties of superantigens with gp130 through structural and functional in vitro analyses. Results: The Superantigen, SEA, was shown to bind to gp130 in the micromolar range using SPR-analyses (Banke et al., 2014). Moreover, SEA was also shown to activate gp130 signal ...
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Phosphorylation



Phosphorylation is the addition of a phosphate (PO43−) group to a protein or other organic molecule. Phosphorylation and its counterpart, dephosphorylation, turn many protein enzymes on and off, thereby altering their function and activity. Protein phosphorylation is one type of post-translational modification.Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2015, the Medline database returns over 240,000 articles on the subject, largely on protein phosphorylation).
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