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Off-label utilization of antipsychotics
Off-label utilization of antipsychotics

... Only one significant change over the 5 index days was observed. The percentage of patients treated with atypical antipsychotics increased over the observation period. The proportions for the 5 index days were 25.5%, 22.5%, 29.4%, 33.3% and 53.3% respectively, the differences being statistically ...
Newron to re-submit US NDA for Xadago® (safinamide)
Newron to re-submit US NDA for Xadago® (safinamide)

... This document contains forward-looking statements, including (without limitation) about (1) Newron’s ability to develop and expand its business, successfully complete development of its current product candidates and current and future collaborations for the development and commercialisation of its ...
Pharmacologic Management of the Geriatric Patient
Pharmacologic Management of the Geriatric Patient

... The most popular products used by adults for health reasons in the past 30 days were: o fish oil/omega 3/DHA (37.4%) o glucosamine (19.9%) o echinacea (19.8%) o flaxseed oil or pills (15.9%) o ginseng (14.1%) 52% of adult respondents said they had used some type of supplement in the last 30 days o m ...
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... nervous system with cholinesterase inhibitors (I-ChE).6 The Brazilian Academy of Neurology recommends treatment with cholinesterase inhibitors as effective for Alzheimer’s disease.7 Currently, three I-ChEs are fully approved for clinical use: Rivastigmine, Galantamine and Donepezil.8 In the medical ...
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Starlix - Novartis Pharmaceuticals Corporation

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NurseAdvise-ERR - Indiana State Nurses Association

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ZAROXOLYN 5mg tablets ZAROXOLYN 10 mg tablets Metolazone
ZAROXOLYN 5mg tablets ZAROXOLYN 10 mg tablets Metolazone

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Generic Drugs: Questions and Answers

... and does occur during manufacturing, for both brand name and generic drugs. When a drug, generic or brand name, is mass-produced, very small variations in purity, size, strength, and other parameters are permitted. FDA limits how much variability is acceptable. Generic drugs are required to have the ...
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ksir_ch05 - Homework Market

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Novel treatments for idiopathic pulmonary fibrosis

... pulmonary arterial hypertension and lung cancer. In addition, the co-administration of pirfenidone and nintedanib is appealing given the large number of fibrotic pathways likely to be involved in disease pathobiology and the potential synergistic effects. However, at present, there are no robust dat ...
wyeth and pfizer agree to pay $784.6 million to resolve allegations
wyeth and pfizer agree to pay $784.6 million to resolve allegations

... which is used to determine the quarterly rebate to pay the State for each drug, to be understated during the Relevant Period. The governments alleged that Wyeth concealed, avoided or decreased its obligation to pay Medicaid Drug Rebates to the State for Protonix Oral tablets and Protonix IV. Because ...
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annexure-ii

... a model drug having high solubility. In placebo -controlled studies in patients with coronary heart disease and exertional anginal, trimetazidine hydrochlorode enhanced exercised tolerance and delayed ischemia onset without significantly modifying heart rate, blood pressure or both4.Because of its h ...
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... derailed, killing 16 people and injuring dozens of others. It was the deadliest mishap in Amtrak history. Public sentiment turned to outrage when it was learned that two members of the Amtrak crew were under the influence of marijuana at the time of the derailment. They allegedly smoked marijuana mi ...
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Optical Isomerism

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Antimycobacterial Drugs

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Results of Some Urological Problems with Cernilton

... The results achieved in the cases presented above are similar to those obtained by the other authors. Allergic reaction to the main substance of the drug (pollen) in some individuals is a very well known factor. Cernilton, being a pollen extract also arouses the same dubious thought. But in 1960 Hel ...
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Drug-Interaction-Preferences

...  Major – interactions that may be life-threatening or can cause permanent damage.  Moderate – interactions can cause a patient’s condition to deteriorate and may require additional care or hospitalization.  Minor – interactions that are bothersome, but otherwise not clinically detrimental to the ...
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Bad Pharma



Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.
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