Combined effects of bisphosphonate and radiation on fibrosarcoma
... are exposed to low concentration of ZOL for only a few hours. So, when using ZOL in practice, combined treatment with other agents should be encouraged, we suppose. The aim of this study was to determine whether the anti-tumor effect of BPs can be strengthen when it was combined with other antitumor ...
... are exposed to low concentration of ZOL for only a few hours. So, when using ZOL in practice, combined treatment with other agents should be encouraged, we suppose. The aim of this study was to determine whether the anti-tumor effect of BPs can be strengthen when it was combined with other antitumor ...
Xolair for the treatment of chronic spontaneous urticuria (CSU
... This report was commissioned by the Dutch Association for Dermatology and Venereology (NVDV) in order to evaluate the health economic model for omalizumab (Xolair®), a novel drug against chronic idiopathic / spontaneous urticaria. Xolair has been registered since February 2014 for the indication ...
... This report was commissioned by the Dutch Association for Dermatology and Venereology (NVDV) in order to evaluate the health economic model for omalizumab (Xolair®), a novel drug against chronic idiopathic / spontaneous urticaria. Xolair has been registered since February 2014 for the indication ...
n = 40 - Corporate
... AZA, azathiopine; Ig, immunoglobulin; HCQ, hydroxychloroquine; LEF, leflunomide; SSZ, sulfasalazine. ...
... AZA, azathiopine; Ig, immunoglobulin; HCQ, hydroxychloroquine; LEF, leflunomide; SSZ, sulfasalazine. ...
CONTENTS - Health Sciences Authority
... of these patients have pre-existing allergic medical conditions such as asthma or are known to be allergic to certain medications. All the eight patients have since recovered or are recovering. The other two of the other serious reports are currently still under review. The Vigilance Branch will pro ...
... of these patients have pre-existing allergic medical conditions such as asthma or are known to be allergic to certain medications. All the eight patients have since recovered or are recovering. The other two of the other serious reports are currently still under review. The Vigilance Branch will pro ...
REQUIP®
... study described above; concomitant use of selegiline was allowed, but patients were not permitted to use anticholinergics or amantadine during the study. Patients had a mean disease duration of 2 years and limited (not more than a 6-week period) or no prior exposure to L-dopa. The starting dose of ...
... study described above; concomitant use of selegiline was allowed, but patients were not permitted to use anticholinergics or amantadine during the study. Patients had a mean disease duration of 2 years and limited (not more than a 6-week period) or no prior exposure to L-dopa. The starting dose of ...
SEDATIVE/HYPNOTICS (Antianxiety Drugs)
... • Minimal muscle relaxing and anticonvulsant effect. • Rapidly metabolized by liver enzymes into inactive metabolites. • Dosage should be reduced in patients with hepatic dysfunction, the elderly and patients ...
... • Minimal muscle relaxing and anticonvulsant effect. • Rapidly metabolized by liver enzymes into inactive metabolites. • Dosage should be reduced in patients with hepatic dysfunction, the elderly and patients ...
Fever: beneficial and detrimental effects of antipyretics
... Lowering of the temperature of patients with stroke or brain injuries has been advocated as a means of improving cognitive and behavioral outcomes. The induction of hypothermia in humans, by means of external cooling, has been shown in several small studies to be effective in this regard [24,25]. Ho ...
... Lowering of the temperature of patients with stroke or brain injuries has been advocated as a means of improving cognitive and behavioral outcomes. The induction of hypothermia in humans, by means of external cooling, has been shown in several small studies to be effective in this regard [24,25]. Ho ...
Principles of Pediatrics Pharmacotherapy
... body weight or surface area of a pediatric patient extrapolated from adult data. BA, PK, PD, efficacy, and adverse-effect information can differ markedly between pediatric and adult patients, as well as among pediatric patients, because of differences in age, organ function, and disease state. ...
... body weight or surface area of a pediatric patient extrapolated from adult data. BA, PK, PD, efficacy, and adverse-effect information can differ markedly between pediatric and adult patients, as well as among pediatric patients, because of differences in age, organ function, and disease state. ...
Comparative efficacy and safety and efficacy of systemic 13
... The lower dosage, close family ties, proper patient selection can be some criteria for such response. 13-cis retinoic acid is expensive and creates financial burden on many families. So, a240 low dosage of 20mg/day, cuts down the cost to 1/3rd, and the amount spend in years on antibiotics and variou ...
... The lower dosage, close family ties, proper patient selection can be some criteria for such response. 13-cis retinoic acid is expensive and creates financial burden on many families. So, a240 low dosage of 20mg/day, cuts down the cost to 1/3rd, and the amount spend in years on antibiotics and variou ...
Formulation and In Vitro Evaluation of Minoxidil Topical Gel
... (alopecia universalis). Till date there is no clear etiology and pathogenesis, but it is believed that there are many factors such as autoimmune, hereditary and emotional stress, infectious agents and neurological factors behind it (2). On the other hand, androgenic alopecia or inherited baldness is ...
... (alopecia universalis). Till date there is no clear etiology and pathogenesis, but it is believed that there are many factors such as autoimmune, hereditary and emotional stress, infectious agents and neurological factors behind it (2). On the other hand, androgenic alopecia or inherited baldness is ...
Spectrophotometric Determination of Drugs Using Iodine As Analytical Reagent Sayaji Rao
... dopamine D2 receptor antagonist. Its localization outside the blood –brain barrier and antiemetic properties has made it is a useful adjunct in therapy for Parkinson’s disease. There has been rehabilitated curiosity in antidopaminergic prokinetic agents, a 5-HT4 agonist, from the market. Domperidone ...
... dopamine D2 receptor antagonist. Its localization outside the blood –brain barrier and antiemetic properties has made it is a useful adjunct in therapy for Parkinson’s disease. There has been rehabilitated curiosity in antidopaminergic prokinetic agents, a 5-HT4 agonist, from the market. Domperidone ...
Drug-related morbidity and mortality: Pharmacoepidemiological aspects Anna K. Jönsson
... the patient as well as for society. Suspected ADRs have been reported to occur in about 214% of hospitalised patients. In about 5% of deceased hospitalised patients suspected ADRs may have caused or contributed to the fatal outcome. When a pharmaceutical drug is approved for marketing, the drug has ...
... the patient as well as for society. Suspected ADRs have been reported to occur in about 214% of hospitalised patients. In about 5% of deceased hospitalised patients suspected ADRs may have caused or contributed to the fatal outcome. When a pharmaceutical drug is approved for marketing, the drug has ...
Statins And Liver Disease - Healthcare Professionals
... • UK population-based study – 1.18 million patients – 13,029 with MI 1996-2003 – Statin use resulted in 39% lower all cause mortality – Longer duration = more benefit (19% per year after 2 years) – Same for atorvastatin vs. simvastatin Hippisley-Cox. Effect of statins on the mortality of patients wi ...
... • UK population-based study – 1.18 million patients – 13,029 with MI 1996-2003 – Statin use resulted in 39% lower all cause mortality – Longer duration = more benefit (19% per year after 2 years) – Same for atorvastatin vs. simvastatin Hippisley-Cox. Effect of statins on the mortality of patients wi ...
Selecting Topical and Systemic Agents for Recurrent Aphthous
... actions for disorders characterized by the accumulation of polymorphonuclear leukocytes may explain the benefits obtained in several open studies utilizing continuous colchicine therapy in the prevention of RAS.17,18 Doses of 0.6 mg, administered 3 times daily, appear to not only decrease the severi ...
... actions for disorders characterized by the accumulation of polymorphonuclear leukocytes may explain the benefits obtained in several open studies utilizing continuous colchicine therapy in the prevention of RAS.17,18 Doses of 0.6 mg, administered 3 times daily, appear to not only decrease the severi ...
MicroDose Therapeutx and Moerae Matrix Announce
... asthma and COPD, respiratory viruses and infections ‐ including RSV ‐ as well as IBS‐C and constipation. For more information please visit www.mdtx.com About the NHLBI The NHLBI stimulates basic discoveries about the causes of disease, enables the translation of basic discoveries ...
... asthma and COPD, respiratory viruses and infections ‐ including RSV ‐ as well as IBS‐C and constipation. For more information please visit www.mdtx.com About the NHLBI The NHLBI stimulates basic discoveries about the causes of disease, enables the translation of basic discoveries ...
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
... Initial clinical results from the ongoing Phase 1/2 study of ALN-GO1 at the 17th Congress of the International Pediatric Nephrology Association (IPNA), being held September 20 – 24, 2016 in Iguaçu, Brazil, in an oral presentation on Saturday, September 24, at 3:25 pm Brasília Time (2:25 pm ET). Init ...
... Initial clinical results from the ongoing Phase 1/2 study of ALN-GO1 at the 17th Congress of the International Pediatric Nephrology Association (IPNA), being held September 20 – 24, 2016 in Iguaçu, Brazil, in an oral presentation on Saturday, September 24, at 3:25 pm Brasília Time (2:25 pm ET). Init ...
Express Results CLIA-Waived Integrated Cup
... metabolic product of codeine and heroin. Morphine is detectable in the urine for several days after an opiate dose.1 The Express Results™ Integrated Multi-Drug Screen Cup yields a positive result when the morphine in urine exceeds 2,000 ng/mL. This is the suggested screening cut-off for positive spe ...
... metabolic product of codeine and heroin. Morphine is detectable in the urine for several days after an opiate dose.1 The Express Results™ Integrated Multi-Drug Screen Cup yields a positive result when the morphine in urine exceeds 2,000 ng/mL. This is the suggested screening cut-off for positive spe ...
Anticoagulants
... Higher doses of more potent statins (atorvastatin and simvastatin) also can reduce triglyceride levels caused by elevated VLDL levels (LDL receptor can recognize Apo-E in VLDL). Also reduce VLDL synthesis in liver - requires cholesterol Some statins are also indicated for raising HDL-C levels ...
... Higher doses of more potent statins (atorvastatin and simvastatin) also can reduce triglyceride levels caused by elevated VLDL levels (LDL receptor can recognize Apo-E in VLDL). Also reduce VLDL synthesis in liver - requires cholesterol Some statins are also indicated for raising HDL-C levels ...
product monograph
... Symptomatic chronic lymphocytic leukemia (CLL) who have received no prior treatment. Approval of TREANDA in CLL is based on a progression-free survival and overall response rate advantage of TREANDA over chlorambucil in a single randomized controlled trial. Prolongation of overall survival or improv ...
... Symptomatic chronic lymphocytic leukemia (CLL) who have received no prior treatment. Approval of TREANDA in CLL is based on a progression-free survival and overall response rate advantage of TREANDA over chlorambucil in a single randomized controlled trial. Prolongation of overall survival or improv ...
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES KARNATAKA
... The estimation of above said enzymes, bilirubin and proteins will be considered as the criteria for the assessment of the result, along with the histopathological evaluations. ...
... The estimation of above said enzymes, bilirubin and proteins will be considered as the criteria for the assessment of the result, along with the histopathological evaluations. ...
secnidazole
... administration, its place in therapy should be evaluated in this context. As such, available clinical data suggest that the main place of one-dose secnidazole is as an alternative to multiple-dose metronidazole for treatment of mild or moderate intestinal amebiasis, particularly in rural endemic reg ...
... administration, its place in therapy should be evaluated in this context. As such, available clinical data suggest that the main place of one-dose secnidazole is as an alternative to multiple-dose metronidazole for treatment of mild or moderate intestinal amebiasis, particularly in rural endemic reg ...
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... nausea and vomiting (CINV) in adults and children 4 to 18 years old (three doses of 0.15 mg/kg), and for the prevention of post-operative nausea and vomiting (PONV) in adults and children 2 to 12 years old (single 0.1 mg/kg dose). Although there is little information available on the use of Zofran i ...
... nausea and vomiting (CINV) in adults and children 4 to 18 years old (three doses of 0.15 mg/kg), and for the prevention of post-operative nausea and vomiting (PONV) in adults and children 2 to 12 years old (single 0.1 mg/kg dose). Although there is little information available on the use of Zofran i ...
TRANSDERMAL DRUG DELIVERY SYSTEMS
... to produce intimate contact with the skin is more often the source of cutaneous reactivity & not the drug. many of the inactive ingredients used in topical pharmaceutical dosage forms have the ability to alter the barrier function of the skin ...
... to produce intimate contact with the skin is more often the source of cutaneous reactivity & not the drug. many of the inactive ingredients used in topical pharmaceutical dosage forms have the ability to alter the barrier function of the skin ...
Partial Seizures - My Illinois State
... Dopaminergic agents are used to help replace the lost dopamine or enhance the function of the few neurons that are left to produce their own. Levodopa and carbidopa o Directly replace dopamine o Levodopa can pass through blood-brain barrier to get to site of action in the brain; dopamine cannot ...
... Dopaminergic agents are used to help replace the lost dopamine or enhance the function of the few neurons that are left to produce their own. Levodopa and carbidopa o Directly replace dopamine o Levodopa can pass through blood-brain barrier to get to site of action in the brain; dopamine cannot ...
Bad Pharma
Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.