maxzide
... edema in patients who develop hypokalemia on hydrochlorothiazide alone. 2. MAXZIDE is also indicated for those patients who require a thiazide diuretic and in whom the development of hypokalemia cannot be risked (e.g., patients on concomitant digitalis preparations, or with a history of cardiac arrh ...
... edema in patients who develop hypokalemia on hydrochlorothiazide alone. 2. MAXZIDE is also indicated for those patients who require a thiazide diuretic and in whom the development of hypokalemia cannot be risked (e.g., patients on concomitant digitalis preparations, or with a history of cardiac arrh ...
Renal Analgesic Brochure
... Opioid associated adverse drug reactions (sedation, respiratory depression, nausea and vomiting, constipation, itchiness); irritation/erythema, pruritus at application site. Risk of accidental overdose when used in acute pain, nontolerant individuals, or through careless disposal. Might precipitate ...
... Opioid associated adverse drug reactions (sedation, respiratory depression, nausea and vomiting, constipation, itchiness); irritation/erythema, pruritus at application site. Risk of accidental overdose when used in acute pain, nontolerant individuals, or through careless disposal. Might precipitate ...
DIPYRIDAMOLE TABLETS USP 25 MG, 50 MG AND 75 MG
... Dipyridamole has a vasodilatory effect and should be used with caution in patients with severe coronary artery disease (e.g., unstable angina or recently sustained myocardial infarction). Chest pain may be aggravated in patients with underlying coronary artery disease who are receiving dipyridamole. ...
... Dipyridamole has a vasodilatory effect and should be used with caution in patients with severe coronary artery disease (e.g., unstable angina or recently sustained myocardial infarction). Chest pain may be aggravated in patients with underlying coronary artery disease who are receiving dipyridamole. ...
Assessment Report For Sprycel
... The MAH did not conduct new non-clinical studies to support the use of dasatinib in the patient population covered by the new indication. This is acceptable as the initial marketing authorisation application included most of the studies required for a long term use in patients with long life expecta ...
... The MAH did not conduct new non-clinical studies to support the use of dasatinib in the patient population covered by the new indication. This is acceptable as the initial marketing authorisation application included most of the studies required for a long term use in patients with long life expecta ...
Milk Thistle and Its Derivative Compounds: A Review of
... with hepatic failure. Up to one-third of people reported using milk thistle compounds to supplement therapy for chronic viral hepatitis,1 and other clinicbased reports suggest that use by persons with chronic liver disease is even higher.2,3 Milk thistle seed extracts have been used for centuries fo ...
... with hepatic failure. Up to one-third of people reported using milk thistle compounds to supplement therapy for chronic viral hepatitis,1 and other clinicbased reports suggest that use by persons with chronic liver disease is even higher.2,3 Milk thistle seed extracts have been used for centuries fo ...
Simultaneous Determination of Piracetam and its Four
... The mobile phase is composed of an aqueous solution containing 0.2 g/L of triethyl amine–acetonitrile (85:15, v/v). The pH of the mobile phase was adjusted to 6.5 with phosphoric acid at a flow rate of 1 mL/min at ambient temperature and UV detection at 205 nm. The developed method was found to give ...
... The mobile phase is composed of an aqueous solution containing 0.2 g/L of triethyl amine–acetonitrile (85:15, v/v). The pH of the mobile phase was adjusted to 6.5 with phosphoric acid at a flow rate of 1 mL/min at ambient temperature and UV detection at 205 nm. The developed method was found to give ...
![[Product Monograph Template - Standard]](http://s1.studyres.com/store/data/015563581_1-5b36e170778605d114d7f22617c09a70-300x300.png)
[Product Monograph Template - Standard]
... Clinical Trial Adverse Drug Reactions Prospective clinical trials were not conducted for polymyxin B sulphate. Therefore drug-related adverse reactions that could occur are derived from adverse drug reporting from retrospective clinical studies. Renal and Urinary Disorders: albuminuria, cylindruria ...
... Clinical Trial Adverse Drug Reactions Prospective clinical trials were not conducted for polymyxin B sulphate. Therefore drug-related adverse reactions that could occur are derived from adverse drug reporting from retrospective clinical studies. Renal and Urinary Disorders: albuminuria, cylindruria ...
Advances in phage display technology for drug discovery
... Random phage peptide libraries are one of the most common types of phage display constructs. Using degenerate oligonucleotides introduced into the phage genome, the linear random peptide library can be obtained. The random oligonucleotides are cloned between the coding sequence of the signal peptide ...
... Random phage peptide libraries are one of the most common types of phage display constructs. Using degenerate oligonucleotides introduced into the phage genome, the linear random peptide library can be obtained. The random oligonucleotides are cloned between the coding sequence of the signal peptide ...
HIGHLIGHTS OF PRESCRIBING INFORMATION These - PI
... serum concentrations of methotrexate and/or its metabolite, possibly leading to toxicity. With high dose methotrexate administration, consider a temporary withdrawal of PRILOSEC (5.11, 7). ----------------------------------------- ADVERSE REACTIONS ----------------------------------------Adults: Mos ...
... serum concentrations of methotrexate and/or its metabolite, possibly leading to toxicity. With high dose methotrexate administration, consider a temporary withdrawal of PRILOSEC (5.11, 7). ----------------------------------------- ADVERSE REACTIONS ----------------------------------------Adults: Mos ...
Peer-reviewed Article PDF
... complexity [22]. Volunteers were required to be non-smokers or exsmokers (less than 5 pack-years and stopped smoking for more than 1 year), have normal blood pressure and heart rate (supine), normal laboratory tests, have a 12-lead ECG with computerized protocol interpretation considered as normal o ...
... complexity [22]. Volunteers were required to be non-smokers or exsmokers (less than 5 pack-years and stopped smoking for more than 1 year), have normal blood pressure and heart rate (supine), normal laboratory tests, have a 12-lead ECG with computerized protocol interpretation considered as normal o ...
REVIEWS
... Methods: We performed a PubMed literature search for reviews and case reports on drugs that exacerbate or induce psoriasis. Articles were screened by title and abstract and then examined for their findings and references. Results: Drugs most often reported to exacerbate or induce psoriasis were β -b ...
... Methods: We performed a PubMed literature search for reviews and case reports on drugs that exacerbate or induce psoriasis. Articles were screened by title and abstract and then examined for their findings and references. Results: Drugs most often reported to exacerbate or induce psoriasis were β -b ...
Strategies for ocular siRNA delivery: Potential and limitations of non-viral nanocarriers
... double-stranded non-coding RNA molecules that play an ...
... double-stranded non-coding RNA molecules that play an ...
Influence of Vesicle Size, Lipid Composition, and
... (55:45; mol/mol) vesicles sized through filters with a 200-nm pore size and loaded employing transmembrane pH gradients to achieve a doxorubicin-to-lipid ratio of 0.3:1 (wt/wt) increased the LD»of free drug by approximately twofold. Removing cholesterol or decreasing the drug-tolipid ratio in EPC/c ...
... (55:45; mol/mol) vesicles sized through filters with a 200-nm pore size and loaded employing transmembrane pH gradients to achieve a doxorubicin-to-lipid ratio of 0.3:1 (wt/wt) increased the LD»of free drug by approximately twofold. Removing cholesterol or decreasing the drug-tolipid ratio in EPC/c ...
ZOFRAN Tablets, Oral Solution and Injection PRODUCT MONOGRAPH
... ondansetron is administered with alcohol, temazepam, furosemide, tramadol or propofol. Ondansetron is metabolised by multiple hepatic cytochrome P450 enzymes: CYP3A4, CYP2D6 and CYP1A2. Despite the multiplicity of metabolic enzymes capable of metabolising ondansetron which can compensate for an incr ...
... ondansetron is administered with alcohol, temazepam, furosemide, tramadol or propofol. Ondansetron is metabolised by multiple hepatic cytochrome P450 enzymes: CYP3A4, CYP2D6 and CYP1A2. Despite the multiplicity of metabolic enzymes capable of metabolising ondansetron which can compensate for an incr ...
Dyslipidemia update by Dr Sarma
... The contents of my today’s presentations are made available in a CD-ROM format ...
... The contents of my today’s presentations are made available in a CD-ROM format ...
Marine Origin Polysaccharides in Drug Delivery Systems
... and erosion of the carrier. Alginate has the ability of cross-linking with Ca2+ ions through an ionotropic gelation process, usually above pH 6 [42]. Ca2+ is not the only ion capable of promoting ionotropic gelation of alginate: Ba2+ or Zn2+ ions may also be used for that propose [43]. Virtually any ...
... and erosion of the carrier. Alginate has the ability of cross-linking with Ca2+ ions through an ionotropic gelation process, usually above pH 6 [42]. Ca2+ is not the only ion capable of promoting ionotropic gelation of alginate: Ba2+ or Zn2+ ions may also be used for that propose [43]. Virtually any ...
Licorice - Glycyrrhiza glabra
... Therefore, the German health authorities warn that licorice should not be used for more than four to six weeks in therapeutic doses, without medical advice. During this period of time, a diet rich in potassium (such as bananas and dried apricots) is recommended. The potassium loss can also produce i ...
... Therefore, the German health authorities warn that licorice should not be used for more than four to six weeks in therapeutic doses, without medical advice. During this period of time, a diet rich in potassium (such as bananas and dried apricots) is recommended. The potassium loss can also produce i ...
Counterfeit Prescription Pills Containing Fentanyls: A
... The 2014 National Survey on Drug Use and Health estimated that there were 4.3 million nonmedical users of pain relievers in the United States in 2014; a population second only in size to marijuana users. High demand for authentic prescription drugs strongly incentivizes traffickers to produce counte ...
... The 2014 National Survey on Drug Use and Health estimated that there were 4.3 million nonmedical users of pain relievers in the United States in 2014; a population second only in size to marijuana users. High demand for authentic prescription drugs strongly incentivizes traffickers to produce counte ...
COCA ANO COCAINE AS MEDICINES: AN IIlSTOItlCAL
... uyster ia , melancholia , and other illnosses - cven as an aphrodisiac and a I)"nign subst.itute for caffcinr-. In 1863 Ango!o Mariani, a Corsican chr-rnist, .atcntcd a preparatio n of coca ex tract ane! wine, "Vin Muriani ", wh i.-b ''V,'" .ually made h is f'ortuno : it became one of thr- most. pop ...
... uyster ia , melancholia , and other illnosses - cven as an aphrodisiac and a I)"nign subst.itute for caffcinr-. In 1863 Ango!o Mariani, a Corsican chr-rnist, .atcntcd a preparatio n of coca ex tract ane! wine, "Vin Muriani ", wh i.-b ''V,'" .ually made h is f'ortuno : it became one of thr- most. pop ...
February 2, 2010 Dockets Management Branch (HFA
... please provide more clarity on the exact scope of the document. The guidance document could be organized in a more cohesive manner. Given that the FDA mentions tiered strategies for immunogenicity testing, and that the general practice is to conduct: a) screening, b) confirmatory, c) neutralizing an ...
... please provide more clarity on the exact scope of the document. The guidance document could be organized in a more cohesive manner. Given that the FDA mentions tiered strategies for immunogenicity testing, and that the general practice is to conduct: a) screening, b) confirmatory, c) neutralizing an ...
TCCC Change Prop 1403 Ondansetron 150403 JSOM
... Since September 16, 2009, there has been an FDA Black Box Warning for the injectable form of promethazine due to “the risk of serious tissue injury when this drug is administered incorrectly.”17 Foret, et al, report two cases of accidental intra-arterial promethazine injection that led to necrosis, ...
... Since September 16, 2009, there has been an FDA Black Box Warning for the injectable form of promethazine due to “the risk of serious tissue injury when this drug is administered incorrectly.”17 Foret, et al, report two cases of accidental intra-arterial promethazine injection that led to necrosis, ...
If this leaflet is difficult to see or read please contact the following
... Vancomycin is indicated in potentially life-threatening infections which cannot be treated with other effective, less toxic antimicrobial drugs, including the penicillins and cephalosporins. Vancomycin is useful in the therapy of severe staphylococcal infections in patients who cannot receive or who ...
... Vancomycin is indicated in potentially life-threatening infections which cannot be treated with other effective, less toxic antimicrobial drugs, including the penicillins and cephalosporins. Vancomycin is useful in the therapy of severe staphylococcal infections in patients who cannot receive or who ...
Bad Pharma
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Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.