Pharmacotherapy of Smoking Cessation
... Cigarette smoking is responsible for $50 billion annually in direct medical costs, and $47 billion in indirect, nonmedical costs.2 Despite widespread efforts to educate the public on the risks of smoking, the prevalence of smoking in the United States remains high. Approximately 46 million American ...
... Cigarette smoking is responsible for $50 billion annually in direct medical costs, and $47 billion in indirect, nonmedical costs.2 Despite widespread efforts to educate the public on the risks of smoking, the prevalence of smoking in the United States remains high. Approximately 46 million American ...
1. name of the medicinal product
... There was an increased reporting of lower respiratory tract infections (particularly pneumonia and bronchitis) in the TORCH study in patients with COPD receiving salmeterol/fluticasone propionate 50/500 micrograms twice daily compared with placebo as well as in studies SCO40043 and SCO100250 compari ...
... There was an increased reporting of lower respiratory tract infections (particularly pneumonia and bronchitis) in the TORCH study in patients with COPD receiving salmeterol/fluticasone propionate 50/500 micrograms twice daily compared with placebo as well as in studies SCO40043 and SCO100250 compari ...
Epinephrine_1871-01_PI_Art3 without Legend
... Each epinephrine injection, USP auto-injector contains a single dose of epinephrine for single use injection. Since the doses of epinephrine delivered from epinephrine injection, USP auto-injector are fixed, consider using other forms of injectable epinephrine if doses lower than 0.15 mg are deemed ...
... Each epinephrine injection, USP auto-injector contains a single dose of epinephrine for single use injection. Since the doses of epinephrine delivered from epinephrine injection, USP auto-injector are fixed, consider using other forms of injectable epinephrine if doses lower than 0.15 mg are deemed ...
Product Information: Lisdexamfetamine dimesilate
... final doses of 30, 50, or 70 mg of VYVANSE or placebo once daily in the morning for four weeks. All subjects receiving VYVANSE were initiated on 30 mg for the first week of treatment. Subjects assigned to the 50 and 70 mg dose groups were titrated by 20 mg per week until they achieved their assigned ...
... final doses of 30, 50, or 70 mg of VYVANSE or placebo once daily in the morning for four weeks. All subjects receiving VYVANSE were initiated on 30 mg for the first week of treatment. Subjects assigned to the 50 and 70 mg dose groups were titrated by 20 mg per week until they achieved their assigned ...
Martindale: The Complete Drug Reference
... neutropenia,5 and agranulocytosis6 occurring in patients given diclofenac. Localised spontaneous bleeding,7 bruising,8 inhibition of platelet aggregation,7 and prolonged bleeding time8 have been reported. 1. 1. The International Agranulocytosis and Aplastic Anemia Study. Risks of agranulocytosis and ...
... neutropenia,5 and agranulocytosis6 occurring in patients given diclofenac. Localised spontaneous bleeding,7 bruising,8 inhibition of platelet aggregation,7 and prolonged bleeding time8 have been reported. 1. 1. The International Agranulocytosis and Aplastic Anemia Study. Risks of agranulocytosis and ...
Theo-24®(theophylline anhydrous) Extended
... T heo -24 ® capsules co ntain hundreds o f co ated beads o f theo phylline. Each bead is an individual extended-release delivery system. After disso lutio n o f the capsules these beads are released and distributed in the g astro intestinal tract, thus minimizing the pro bability o f hig h lo cal co ...
... T heo -24 ® capsules co ntain hundreds o f co ated beads o f theo phylline. Each bead is an individual extended-release delivery system. After disso lutio n o f the capsules these beads are released and distributed in the g astro intestinal tract, thus minimizing the pro bability o f hig h lo cal co ...
Prescribing Information - PI
... serum concentrations of methotrexate and/or its metabolite, possibly leading to toxicity. With high dose methotrexate administration, consider a temporary withdrawal of PRILOSEC. (5.11, 7). ----------------------------------------- ADVERSE REACTIONS ----------------------------------------Adults: Mo ...
... serum concentrations of methotrexate and/or its metabolite, possibly leading to toxicity. With high dose methotrexate administration, consider a temporary withdrawal of PRILOSEC. (5.11, 7). ----------------------------------------- ADVERSE REACTIONS ----------------------------------------Adults: Mo ...
amoxicillin: a broad spectrum antibiotic
... immunocompromised patients, those undergoing surgery, and infections in haemodialysis patients. There was a requirement for broad‐spectrum antibiotics active against resistant organisms and in mixed infections14. The 1970s saw the introduction of a number of important new ...
... immunocompromised patients, those undergoing surgery, and infections in haemodialysis patients. There was a requirement for broad‐spectrum antibiotics active against resistant organisms and in mixed infections14. The 1970s saw the introduction of a number of important new ...
Diamorphine Hydrochloride BP 100 mg Lyophilisate for solution for
... The finished product specification is satisfactory. Acceptance limits have been justified with respect to conventional pharmaceutical requirements and, where appropriate, safety. Test methods have been described and have been adequately validated, as appropriate. Batch data have been provided and co ...
... The finished product specification is satisfactory. Acceptance limits have been justified with respect to conventional pharmaceutical requirements and, where appropriate, safety. Test methods have been described and have been adequately validated, as appropriate. Batch data have been provided and co ...
Product Monograph
... Episodes of falling asleep while engaged in activities of daily living have also been reported in patients taking other dopaminergic agents, therefore, symptoms may not be alleviated by substituting these products. While dose reduction clearly reduces the degree of somnolence, there is insufficient ...
... Episodes of falling asleep while engaged in activities of daily living have also been reported in patients taking other dopaminergic agents, therefore, symptoms may not be alleviated by substituting these products. While dose reduction clearly reduces the degree of somnolence, there is insufficient ...
2 Long-acting agonists: a new perspective
... related to asthma, but the clinical relevance of these effects Is not clear at present. Long-term studies up to one year with both new drugs have not shown any unexpected side-effects, and no tachyphylaxis to ~-adrenoceptor stimulation has been reported. Patients appear to strongly prefer the new dr ...
... related to asthma, but the clinical relevance of these effects Is not clear at present. Long-term studies up to one year with both new drugs have not shown any unexpected side-effects, and no tachyphylaxis to ~-adrenoceptor stimulation has been reported. Patients appear to strongly prefer the new dr ...
PRILOSEC (omeprazole) (omeprazole magnesium) DELAYED-RELEASE CAPSULES
... The efficacy of PRILOSEC used for longer than 8 weeks in these patients has not been established. If a patient does not respond to 8 weeks of treatment, an additional 4 weeks of treatment may be given. If there is recurrence of erosive esophagitis or GERD symptoms (eg, heartburn), additional 4-8 wee ...
... The efficacy of PRILOSEC used for longer than 8 weeks in these patients has not been established. If a patient does not respond to 8 weeks of treatment, an additional 4 weeks of treatment may be given. If there is recurrence of erosive esophagitis or GERD symptoms (eg, heartburn), additional 4-8 wee ...
antihistamines in allergic disease
... onset of effect occurs within 1-3 hours; their duration of action varies from several hours to 24 hours, (second-generation drugs being generally around 24 hours) (Table II).7 First-generation antihistamines and some of the second-generation agents are oxidatively metabolised by the hepatic cytochro ...
... onset of effect occurs within 1-3 hours; their duration of action varies from several hours to 24 hours, (second-generation drugs being generally around 24 hours) (Table II).7 First-generation antihistamines and some of the second-generation agents are oxidatively metabolised by the hepatic cytochro ...
Naloxone - Spirit of Healing: Alberta First Nations Conquering
... If the second dose of Naloxone does still not revive the person, something else may be wrong (either the heart has already stopped, there are no opioids in their system, non-opioid drugs are the cause of the overdose, or the opioid drugs were too strong for the Naloxone) ...
... If the second dose of Naloxone does still not revive the person, something else may be wrong (either the heart has already stopped, there are no opioids in their system, non-opioid drugs are the cause of the overdose, or the opioid drugs were too strong for the Naloxone) ...
Targeting proteases: successes, failures and future prospects
... can lead to pathologies such as cardiovascular and inflammatory diseases, cancer, osteoporosis and neurological disorders. Several small-molecule drugs targeting proteases are already on the market and many more are in development. The status of human protease research and prospects for future prote ...
... can lead to pathologies such as cardiovascular and inflammatory diseases, cancer, osteoporosis and neurological disorders. Several small-molecule drugs targeting proteases are already on the market and many more are in development. The status of human protease research and prospects for future prote ...
Pharmaceutical Statistics Practical and Clinical Application
... This newest edition includes some significant additions. Most important is the inclusion of a coauthor, Charles (Chuck) Bon. Chuck has extensive practical experience as a chemist and statistician. His assistance in preparing the 4th edition adds some new dimensions, and new thoughts to the book. Ano ...
... This newest edition includes some significant additions. Most important is the inclusion of a coauthor, Charles (Chuck) Bon. Chuck has extensive practical experience as a chemist and statistician. His assistance in preparing the 4th edition adds some new dimensions, and new thoughts to the book. Ano ...
Two-Piece Hard Capsules for Pharmaceutical
... With the advent of high-speed filling machines, it quickly became apparent that this design was inadequate to meet the needs of the industry. One of the first problems observed was the ease with which the cap and body would separate after filling and during shipping. This was often due to air entrap ...
... With the advent of high-speed filling machines, it quickly became apparent that this design was inadequate to meet the needs of the industry. One of the first problems observed was the ease with which the cap and body would separate after filling and during shipping. This was often due to air entrap ...
Medicated Chewing Gum- A Mobile Oral Drug Delivery System
... Duration of action is increased. Aspirin, Dimenhydrinate and Caffeine 4 shows faster absorption through MCG than tablets. As a delivery systemic administration of drug via the oral mucosa it has the potential to overcome the problems of short lived action and variations in drug release and retention ...
... Duration of action is increased. Aspirin, Dimenhydrinate and Caffeine 4 shows faster absorption through MCG than tablets. As a delivery systemic administration of drug via the oral mucosa it has the potential to overcome the problems of short lived action and variations in drug release and retention ...
BIAXIN® Filmtab® (clarithromycin tablets, USP) BIAXIN
... from both AIDS and non-AIDS patients. While gene probe techniques may be used to distinguish M. avium species from M. intracellulare, many studies only reported results on M. avium complex (MAC) isolates. Various in vitro methodologies employing broth or solid media at different pH’s, with and witho ...
... from both AIDS and non-AIDS patients. While gene probe techniques may be used to distinguish M. avium species from M. intracellulare, many studies only reported results on M. avium complex (MAC) isolates. Various in vitro methodologies employing broth or solid media at different pH’s, with and witho ...
Inderal (propranolol hydrochloride) Tablets Rx only
... to 80, with atrial fibrillation and ventricular rate >120 beats per minute despite digitalis, received propranolol up to 30 mg t.i.d. Seven patients (70%) achieved ventricular rate reduction to <100 beats per minute. Myocardial Infarction The Beta-Blocker Heart Attack Trial (BHAT) was a National Hea ...
... to 80, with atrial fibrillation and ventricular rate >120 beats per minute despite digitalis, received propranolol up to 30 mg t.i.d. Seven patients (70%) achieved ventricular rate reduction to <100 beats per minute. Myocardial Infarction The Beta-Blocker Heart Attack Trial (BHAT) was a National Hea ...
PRODUCT MONOGRAPH OFLOXACIN TABLETS 200, 300 and 400 mg
... laryngeal, throat or facial edema/swelling, etc.), airway obstruction (including bronchospasm, shortness of breath, and acute respiratory distress), dyspnea, urticaria/hives, itching and other serious skin reactions. A few patients had a history of hypersensitivity reactions. The drug should be disc ...
... laryngeal, throat or facial edema/swelling, etc.), airway obstruction (including bronchospasm, shortness of breath, and acute respiratory distress), dyspnea, urticaria/hives, itching and other serious skin reactions. A few patients had a history of hypersensitivity reactions. The drug should be disc ...
Simultaneous Quantitative Determination of Candesartan cilexetil
... The intra-day and inter-day precisions of the proposed methods were determined by estimating the corresponding responses 3 times on the same day and on 3 different days, over a period of 1 week, for 3 different concentrations of 12.5, 25 and 50 µg/ mL Hydrochlorthiazide and 16, 32 and 64 µg/mL for C ...
... The intra-day and inter-day precisions of the proposed methods were determined by estimating the corresponding responses 3 times on the same day and on 3 different days, over a period of 1 week, for 3 different concentrations of 12.5, 25 and 50 µg/ mL Hydrochlorthiazide and 16, 32 and 64 µg/mL for C ...
Problems of anabolic steroids in sport.
... The control procedures for sampling and samples, and those for the re-check involving the B samples of urine, are subject to exactly the same inspection and verification procedures as adopted for “normal” dope control. Undoubtedly, problems exist at present because of the long time needed between co ...
... The control procedures for sampling and samples, and those for the re-check involving the B samples of urine, are subject to exactly the same inspection and verification procedures as adopted for “normal” dope control. Undoubtedly, problems exist at present because of the long time needed between co ...
Sootheze Six Plus Paracetamol 250mg/5ml Oral Suspension
... Other ingredients Other ingredients consist of pharmaceutical excipients, namely glycerol, xantham gum, avicel, maltitol syrup, polysorbate 80, sodium saccharin, citric acid monohydrate, methyl hydroxybenzoate sodium (E219), propyl hydroxybenzoate sodium (E217), strawberry flavour, and purified wate ...
... Other ingredients Other ingredients consist of pharmaceutical excipients, namely glycerol, xantham gum, avicel, maltitol syrup, polysorbate 80, sodium saccharin, citric acid monohydrate, methyl hydroxybenzoate sodium (E219), propyl hydroxybenzoate sodium (E217), strawberry flavour, and purified wate ...
Bad Pharma
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Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.