literature review ii
... the dispersion method using using PGS and SSG as carriers. Characterization was done by phase solubility, in-vitro release, saturation solubility, permeation, wettability, XRD and FTIR analysis. Solid dispersions showed higher solubility and an improved drug release profile than the pure drug. Solid ...
... the dispersion method using using PGS and SSG as carriers. Characterization was done by phase solubility, in-vitro release, saturation solubility, permeation, wettability, XRD and FTIR analysis. Solid dispersions showed higher solubility and an improved drug release profile than the pure drug. Solid ...
Ocuflox - Allergan
... Additional studies in rats with doses up to 360 mg/kg/day during late gestation showed no adverse effect on late fetal development, labor, delivery, lactation, neonatal viability, or growth of the newborn. There are, however, no adequate and well-controlled studies in pregnant women. OCUFLOX® soluti ...
... Additional studies in rats with doses up to 360 mg/kg/day during late gestation showed no adverse effect on late fetal development, labor, delivery, lactation, neonatal viability, or growth of the newborn. There are, however, no adequate and well-controlled studies in pregnant women. OCUFLOX® soluti ...
Preventing Occupational Exposure to Antineoplastic and Other
... growth and function of both healthy and diseased cells, resulting in toxic side effects for treated patients. These nonselective actions can also cause adverse effects in health care workers who are inadvertently exposed to hazardous drugs. Early concerns about occupational exposure to antineoplasti ...
... growth and function of both healthy and diseased cells, resulting in toxic side effects for treated patients. These nonselective actions can also cause adverse effects in health care workers who are inadvertently exposed to hazardous drugs. Early concerns about occupational exposure to antineoplasti ...
An approach to bypass the blood brain barrier
... soluble molecules transport across the membrane where hydrophilic solutes demonstrate minimal permeation.5 The BBB impedes the use, for example, of many of the newer genetically engineered drugs, such as humane recombinant neurotrophic factors and other therapeutic agents that can protect brain cell ...
... soluble molecules transport across the membrane where hydrophilic solutes demonstrate minimal permeation.5 The BBB impedes the use, for example, of many of the newer genetically engineered drugs, such as humane recombinant neurotrophic factors and other therapeutic agents that can protect brain cell ...
3 0 M a r c h 1 6 ,
... levels than a fixed dosage of every six (6) hours. In addition, recent studies afford a reasonable correlation between pseudoephedrine plasma levels and an adverse reaction proWhile small increases in pulse rate can be shown in carefully file. steady state plasma levels controlled studies of pseudoe ...
... levels than a fixed dosage of every six (6) hours. In addition, recent studies afford a reasonable correlation between pseudoephedrine plasma levels and an adverse reaction proWhile small increases in pulse rate can be shown in carefully file. steady state plasma levels controlled studies of pseudoe ...
, English, Pages 205
... attributed to the absence of PGE esters, which in turn provides release-retarding ability. Lipids having a low hydrophilic lipophilic balance (HLB), for example Precirol® ATO 5 (HLB = 02), Compritol ATO 888 (HLB = 02) and Gelucire® 39/01 (HLB = 01), have been tried for the preparation of floating ma ...
... attributed to the absence of PGE esters, which in turn provides release-retarding ability. Lipids having a low hydrophilic lipophilic balance (HLB), for example Precirol® ATO 5 (HLB = 02), Compritol ATO 888 (HLB = 02) and Gelucire® 39/01 (HLB = 01), have been tried for the preparation of floating ma ...
LaGuardia Committee Report on Marijuana
... set- up, in which a second variety of toys were used to construct a town setting. The Family Set-up The equipment used in this part of the study consisted of a box of household toys of the type available in the ten-cent store, including beds, dressers, chairs, tables, sinks, a stove, a bathtub, a w ...
... set- up, in which a second variety of toys were used to construct a town setting. The Family Set-up The equipment used in this part of the study consisted of a box of household toys of the type available in the ten-cent store, including beds, dressers, chairs, tables, sinks, a stove, a bathtub, a w ...
Quality indicators and quantity metrics of antibiotic use
... OQI-10 Possible contraindications should be taken into account when antibiotics are prescribed. OQI-11 Antibiotics from the list of essential antibiotics should be available in health facilities that dispense antibiotics. OQI-12 Key antibiotics should not be out of stock in health facilities that di ...
... OQI-10 Possible contraindications should be taken into account when antibiotics are prescribed. OQI-11 Antibiotics from the list of essential antibiotics should be available in health facilities that dispense antibiotics. OQI-12 Key antibiotics should not be out of stock in health facilities that di ...
Niti Sardana and Timothy J. Craig 2011;128;1173 DOI: 10.1542/peds.2011-0546
... concern of blood-borne pathogens. Because of its short half-life, rhC1-INH is unlikely to be effective for prophylaxis. The accelerated clearance of rhC1-INH compared with pdC1-INH, along with higher C1-INH levels after infusion, make it a promising addition to the therapeutic line of drugs for atta ...
... concern of blood-borne pathogens. Because of its short half-life, rhC1-INH is unlikely to be effective for prophylaxis. The accelerated clearance of rhC1-INH compared with pdC1-INH, along with higher C1-INH levels after infusion, make it a promising addition to the therapeutic line of drugs for atta ...
Current Therapeutic Options in Type 2 Diabetes Mellitus: A Practical
... carbohydrate. Recently several combination agents have been released. With these new drugs has come an overwhelming mountain of information, making it difficult for the busy clinician to know how best to manage the ever-increasing portion of patients with type 2 DM. New questions have arisen: Which ...
... carbohydrate. Recently several combination agents have been released. With these new drugs has come an overwhelming mountain of information, making it difficult for the busy clinician to know how best to manage the ever-increasing portion of patients with type 2 DM. New questions have arisen: Which ...
University of Groningen Dry powder inhalation of
... The rapid developments in molecular biology and biotechnology during the past decades have resulted in the successful introduction of a number of biopharmaceuticals (among which many therapeutic peptides and proteins) on the market. Biopharmaceuticals are a special class of medicines in the sense th ...
... The rapid developments in molecular biology and biotechnology during the past decades have resulted in the successful introduction of a number of biopharmaceuticals (among which many therapeutic peptides and proteins) on the market. Biopharmaceuticals are a special class of medicines in the sense th ...
SPECTROPHOTOMETRIC DETERMINATION OF PIZOTIFEN MALEATE IN BULK DRUG AND TABLETS
... reacting with a fixed amount of methyl orange and measuring the absorbance at 522 nm (method A), amaranth and measuring the absorbance at 507 nm (method B) or indigo carmine and measuring the absorbance at 610 nm (method C). Results: In all methods, the amount of NBS reacted corresponds to the amoun ...
... reacting with a fixed amount of methyl orange and measuring the absorbance at 522 nm (method A), amaranth and measuring the absorbance at 507 nm (method B) or indigo carmine and measuring the absorbance at 610 nm (method C). Results: In all methods, the amount of NBS reacted corresponds to the amoun ...
Zolpidem Vitabalans film
... aggression, delusions, anger, nightmares, hallucinations, psychoses, abnormal behaviour, and other adverse behavioural effects may occur when using benzodiazepines or benzodiazepine similar agents. Should these reactions occur, use of the product should be discontinued. These reactions are more like ...
... aggression, delusions, anger, nightmares, hallucinations, psychoses, abnormal behaviour, and other adverse behavioural effects may occur when using benzodiazepines or benzodiazepine similar agents. Should these reactions occur, use of the product should be discontinued. These reactions are more like ...
Levetiracetam in Sodium Chloride Injection
... where patient characteristics and other factors may differ from those prevailing during clinical studies. An inspection of the adverse reactions frequencies provides the prescriber with one basis to estimate the relative contribution of drug and non-drug factors to the adverse reaction incidences in ...
... where patient characteristics and other factors may differ from those prevailing during clinical studies. An inspection of the adverse reactions frequencies provides the prescriber with one basis to estimate the relative contribution of drug and non-drug factors to the adverse reaction incidences in ...
Xanax (alprazolam)
... other tasks requiring alertness while taking this medication. Seniors may be more adversely affected, because it may affect their coordination and reflexes and lead to falls and injury. Taking Xanax with other central nervous system (CNS) depressants such as alcohol, narcotics, and barbiturates may ...
... other tasks requiring alertness while taking this medication. Seniors may be more adversely affected, because it may affect their coordination and reflexes and lead to falls and injury. Taking Xanax with other central nervous system (CNS) depressants such as alcohol, narcotics, and barbiturates may ...
D-Cycloserine as an augmentation strategy for Open Access
... occur and DCS can facilitate this counter-therapeutic process. In other words, DCS can make “good” exposures better and “bad” exposures worse. It should be noted, however, that this is a post-hoc, yet plausible, explanation for some of the negative findings reported in some clinical trials. It is fu ...
... occur and DCS can facilitate this counter-therapeutic process. In other words, DCS can make “good” exposures better and “bad” exposures worse. It should be noted, however, that this is a post-hoc, yet plausible, explanation for some of the negative findings reported in some clinical trials. It is fu ...
Levonorgestrel - Therapeutic Goods Administration
... release of silver ions from the clinical device was found to be 1.65 μg after 28 days; as such, cytotoxic concentrations should not be reached in clinical use. In keeping with this, no adverse local or systemic effects attributable to the presence of the silver ring were observed in 13 week and 9 mo ...
... release of silver ions from the clinical device was found to be 1.65 μg after 28 days; as such, cytotoxic concentrations should not be reached in clinical use. In keeping with this, no adverse local or systemic effects attributable to the presence of the silver ring were observed in 13 week and 9 mo ...
Pharmaceutical Administration and Regulations in Japan (2015)
... http://www.jpma.or.jp/about/issue/gratis/index2.html (Japanese) http://www.jpma.or.jp/english/parj/whole.html (English) ...
... http://www.jpma.or.jp/about/issue/gratis/index2.html (Japanese) http://www.jpma.or.jp/english/parj/whole.html (English) ...
Abstract word count: 199 Text word count: 3273
... Buprenorphine is a semisynthetic opioid partial μ-agonist that has become widely used for therapy of opioid dependency since it was patented in 1969 and was approved for marketing in the United States in 1981. The retail distribution of buprenorphine in the United States (2002-2008) has increased fr ...
... Buprenorphine is a semisynthetic opioid partial μ-agonist that has become widely used for therapy of opioid dependency since it was patented in 1969 and was approved for marketing in the United States in 1981. The retail distribution of buprenorphine in the United States (2002-2008) has increased fr ...
CELEBREX Cardiovascular Risk celecoxib capsules
... anti-inflammatory, analgesic, and antipyretic activities in animal models. The mechanism of action of CELEBREX is believed to be due to inhibition of prostaglandin synthesis, primarily via inhibition of cyclooxygenase-2 (COX-2), and at therapeutic concentrations in humans, CELEBREX does not inhibit ...
... anti-inflammatory, analgesic, and antipyretic activities in animal models. The mechanism of action of CELEBREX is believed to be due to inhibition of prostaglandin synthesis, primarily via inhibition of cyclooxygenase-2 (COX-2), and at therapeutic concentrations in humans, CELEBREX does not inhibit ...
Raloxifene - Centre for Medicines Optimisation
... open to review in the event of significant new evidence emerging. MTRAC can be contacted at the Dept. of Medicines Management, Keele University, Keele, Staffs ST5 5BG ...
... open to review in the event of significant new evidence emerging. MTRAC can be contacted at the Dept. of Medicines Management, Keele University, Keele, Staffs ST5 5BG ...
RegionalRSIProgramGuidelines022006Final
... 7. Cricoid Pressure (Sellick Maneuver) While cricoid pressure may help with visualization, the procedure is not intended for facilitating visualization of the cords. The purpose of cricoid pressure during intubation is to decrease the chance of regurgitation with subsequent aspiration by pressing th ...
... 7. Cricoid Pressure (Sellick Maneuver) While cricoid pressure may help with visualization, the procedure is not intended for facilitating visualization of the cords. The purpose of cricoid pressure during intubation is to decrease the chance of regurgitation with subsequent aspiration by pressing th ...
SOLID LIPID NANOPARTICLES: A REVIEW
... Solid lipid nanoparticles (SLN) are at the forefront of the rapidly developing field of nanotechnology with several potential applications in drug delivery and research. Due to their unique size dependent properties, lipid nanoparticles offer possibility to develop new therapeutics. The ability to i ...
... Solid lipid nanoparticles (SLN) are at the forefront of the rapidly developing field of nanotechnology with several potential applications in drug delivery and research. Due to their unique size dependent properties, lipid nanoparticles offer possibility to develop new therapeutics. The ability to i ...
TETRACYCLINE AND DOXYCYCLINE APPLICATIONS
... drugs may cause alterations of human protein synthesis. If treatment of a patient with renal insufficiency is necessary, dosing should be increased to every 18-24 hours for doxycycline and every 8-12 hours for tetracycline. Outdated tetracycline also has been associated with ...
... drugs may cause alterations of human protein synthesis. If treatment of a patient with renal insufficiency is necessary, dosing should be increased to every 18-24 hours for doxycycline and every 8-12 hours for tetracycline. Outdated tetracycline also has been associated with ...
Bad Pharma
Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.