Vinorelbine - BC Cancer Agency
... 5. Rowinsky EK, Noe DA, Trump DL, et al. Pharmacokinetic, bioavailability, and feasibility study of oral vinorelbine in patients with ...
... 5. Rowinsky EK, Noe DA, Trump DL, et al. Pharmacokinetic, bioavailability, and feasibility study of oral vinorelbine in patients with ...
The practice of digoxin therapeutic drug monitoring - BN6Team-10
... in which TDM is performed is often inappropriate, as highlighted in the article by Sidwell et al in this issue.1 In publications from other countries in the past 15 years, similar conclusions have been drawn, and show that inappropriate use of TDM with digoxin is quite common and not restricted to N ...
... in which TDM is performed is often inappropriate, as highlighted in the article by Sidwell et al in this issue.1 In publications from other countries in the past 15 years, similar conclusions have been drawn, and show that inappropriate use of TDM with digoxin is quite common and not restricted to N ...
Bicillin LA
... Penicillin should be used with caution in individuals with histories of significant allergies and/or asthma. Care should be taken to avoid intravenous or intra-arterial administration, or injection into or near major peripheral nerves or blood vessels, since such injection may produce neurovascular ...
... Penicillin should be used with caution in individuals with histories of significant allergies and/or asthma. Care should be taken to avoid intravenous or intra-arterial administration, or injection into or near major peripheral nerves or blood vessels, since such injection may produce neurovascular ...
(PSD) November 2016 PBAC Meeting - (Word 76KB)
... This submission was not considered by DUSC. The submission presented a market share approach, with estimates based on extrapolated trends of use of PP1M LAI derived from Department of Human Services (DHS) prescription data for the five years to April 2016. The submission assumed PP3M LAI would only ...
... This submission was not considered by DUSC. The submission presented a market share approach, with estimates based on extrapolated trends of use of PP1M LAI derived from Department of Human Services (DHS) prescription data for the five years to April 2016. The submission assumed PP3M LAI would only ...
Express Scripts 2015 Drug Trend Report Workers` Compensation
... medications, specifically Schedule II and III narcotic pain medications. Innovative tools developed by our Workers’ Compensation product and clinical experts, in particular, can address opioid abuse early – before patients progress to misuse. Express Scripts uses powerful data analysis and reporting ...
... medications, specifically Schedule II and III narcotic pain medications. Innovative tools developed by our Workers’ Compensation product and clinical experts, in particular, can address opioid abuse early – before patients progress to misuse. Express Scripts uses powerful data analysis and reporting ...
LEMON BALM Mary Bove, ND An Overview of its Versatility, Effectiveness, and Indications
... Melissa officinalis, commonly called Lemon balm, or balm, is a member of the mint (Labiatiae) family. A fragrant perennial with a pleasant lemon scent, lemon balm has small white to yellow flowers filled with nectar that attracts honeybees. Melissa is Greek for honeybee. This plant is native to Sout ...
... Melissa officinalis, commonly called Lemon balm, or balm, is a member of the mint (Labiatiae) family. A fragrant perennial with a pleasant lemon scent, lemon balm has small white to yellow flowers filled with nectar that attracts honeybees. Melissa is Greek for honeybee. This plant is native to Sout ...
HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHIC METHOD FOR THE SIMULTANEOUS
... To determine the amount of Camylofin dihydrochloride and Mefenemic acid in marketed tablets, twenty tablets were taken, accurately weighed, the average weight of the tablets was found out and finely powdered. An amount of powder equivalent to 50mg of Camylofin dihydrochloride (250 mg of Mefenemic ac ...
... To determine the amount of Camylofin dihydrochloride and Mefenemic acid in marketed tablets, twenty tablets were taken, accurately weighed, the average weight of the tablets was found out and finely powdered. An amount of powder equivalent to 50mg of Camylofin dihydrochloride (250 mg of Mefenemic ac ...
Effects of Tramadol on Fertility Hormones (Follicle Stimulating
... Drug abuse in Nigeria has been indicated to be on the rise in recent years. The use of hard drugs and misuse of prescription drugs for nonmedical purposes cuts across all strata, especially the youths. Tramadol (2[(Dimethylamin) methyl]-1-(3-methoxyphenyl)cyclohexanol) is known for its analgesic pot ...
... Drug abuse in Nigeria has been indicated to be on the rise in recent years. The use of hard drugs and misuse of prescription drugs for nonmedical purposes cuts across all strata, especially the youths. Tramadol (2[(Dimethylamin) methyl]-1-(3-methoxyphenyl)cyclohexanol) is known for its analgesic pot ...
Depression in the Youth and Adolescent - WHO archives
... the setting. Concurrence of other chronic diseases, polymedication, and behavioural symptoms, might mask the psychological symptoms of depression (“depression without sadness”). The suicide rate in the elderly is greater than that for any other segment of the population. Depressed patients incur hig ...
... the setting. Concurrence of other chronic diseases, polymedication, and behavioural symptoms, might mask the psychological symptoms of depression (“depression without sadness”). The suicide rate in the elderly is greater than that for any other segment of the population. Depressed patients incur hig ...
Melvin D. Cheitlin, Adolph M. Hutter, Jr, Ralph G. Brindis,... O. Russell, Jr, Randall M. Zusman, James S. Forrester, Pamela... Use of Sildenafil (Viagra) in Patients With Cardiovascular Disease
... another half a million will experience a heart attack annually and are potential candidates for nitrate therapy.6 Sildenafil is potentially contraindicated in as many as 6 million patients. The introduction of sildenafil citrate (Viagra), a drug that acts as a selective inhibitor of cGMP–specific ph ...
... another half a million will experience a heart attack annually and are potential candidates for nitrate therapy.6 Sildenafil is potentially contraindicated in as many as 6 million patients. The introduction of sildenafil citrate (Viagra), a drug that acts as a selective inhibitor of cGMP–specific ph ...
Lemon Balm - Gaia Herbs
... Melissa officinalis, commonly called Lemon balm, or balm, is a member of the mint (Labiatiae) family. A fragrant perennial with a pleasant lemon scent, lemon balm has small white to yellow flowers filled with nectar that attracts honeybees. Melissa is Greek for honeybee. This plant is native to Sout ...
... Melissa officinalis, commonly called Lemon balm, or balm, is a member of the mint (Labiatiae) family. A fragrant perennial with a pleasant lemon scent, lemon balm has small white to yellow flowers filled with nectar that attracts honeybees. Melissa is Greek for honeybee. This plant is native to Sout ...
... The designs of the four relevant M100240 phase I/II studies with available PK data are summarized in Table I. Biomarkers (i.e., quantifiable surrogate markers measuring in vivo drug effect) for ACE and NEP activity were measured in study A only. In this study, subjects were on a fixed-sodium diet (7 ...
Product Information - Therapeutic Goods Administration
... dose to minimise occurrence of withdrawal symptoms. Patients should be advised to consult with their physician before either increasing the dose or abruptly discontinuing the medication. Rebound phenomena have been described in the context of benzodiazepine use. Rebound insomnia, mood changes, anxie ...
... dose to minimise occurrence of withdrawal symptoms. Patients should be advised to consult with their physician before either increasing the dose or abruptly discontinuing the medication. Rebound phenomena have been described in the context of benzodiazepine use. Rebound insomnia, mood changes, anxie ...
Inadvertent Mix-Up of Morphine and Hydromorphone
... the accepted standard against which other opioids are tested in controlled clinical trials.1 However, because some patients cannot tolerate morphine or have conditions such as renal or hepatic impairment that may impact its use, another opioid may be needed as a replacement drug. Hydromorphone (Dila ...
... the accepted standard against which other opioids are tested in controlled clinical trials.1 However, because some patients cannot tolerate morphine or have conditions such as renal or hepatic impairment that may impact its use, another opioid may be needed as a replacement drug. Hydromorphone (Dila ...
QA324_3_Which_Drugs_Cause_NMS
... Haloperidol is a widely prescribed typical antipsychotic drug, which is recommended as a first line agent for treatment of delirium, and is often used parenterally at high doses. As parenteral antipsychotics and agitation are both risk factors for developing NMS,(4, 5) it is particularly important t ...
... Haloperidol is a widely prescribed typical antipsychotic drug, which is recommended as a first line agent for treatment of delirium, and is often used parenterally at high doses. As parenteral antipsychotics and agitation are both risk factors for developing NMS,(4, 5) it is particularly important t ...
enzyme induction and inhibition
... rifampicin (McInnes and Brodie, 1988). Given this limitation it is possible in man to compare drugs as enzyme inducers by the construction of doseresponse curves. The effect of phenobarbitone on warfarin and antipyrine metabolism has been found to be dose dependent as is the effect of rifampicin on ...
... rifampicin (McInnes and Brodie, 1988). Given this limitation it is possible in man to compare drugs as enzyme inducers by the construction of doseresponse curves. The effect of phenobarbitone on warfarin and antipyrine metabolism has been found to be dose dependent as is the effect of rifampicin on ...
Dietary Supplements: Kava
... variation in AIS scores between subjects so large, such that final AIS score not different between treatments. Difference between Kava extract and placebo not great. ...
... variation in AIS scores between subjects so large, such that final AIS score not different between treatments. Difference between Kava extract and placebo not great. ...
off-label use - Moodle Lille 2
... Off-label prescribing should better serve the patient’s needs than “onlabel” prescription of an alternative medicine. ...
... Off-label prescribing should better serve the patient’s needs than “onlabel” prescription of an alternative medicine. ...
Emerging Issues In The Use Of Methadone
... arrhythmic properties of methadone was presented. This meeting was reconvened on July 20, 2007, and titled Methadone Mortality—A Reassessment. One action that emerged was formation of a multi disciplinary expert panel on the cardiac effects of methadone, charged with formulating a clinical practice ...
... arrhythmic properties of methadone was presented. This meeting was reconvened on July 20, 2007, and titled Methadone Mortality—A Reassessment. One action that emerged was formation of a multi disciplinary expert panel on the cardiac effects of methadone, charged with formulating a clinical practice ...
Prescribing Information as of XXXX ALLEGRA (fexofenadine hydrochloride)
... The mean elimination half-life of fexofenadine was 14.4 hours following administration of 60 mg, twice daily, in normal volunteers. Human mass balance studies documented a recovery of approximately 80% and 11% of the [14C] fexofenadine hydrochloride dose in the feces and urine, respectively. Because ...
... The mean elimination half-life of fexofenadine was 14.4 hours following administration of 60 mg, twice daily, in normal volunteers. Human mass balance studies documented a recovery of approximately 80% and 11% of the [14C] fexofenadine hydrochloride dose in the feces and urine, respectively. Because ...
Updating the List
... Although UKMi cannot assure the quality of the listed resources, all those listed are produced by reputable/well known organisations. URLs are available for download via the MiDatabank administrators and were correct at the time of publication but are liable to change. Where registration is required ...
... Although UKMi cannot assure the quality of the listed resources, all those listed are produced by reputable/well known organisations. URLs are available for download via the MiDatabank administrators and were correct at the time of publication but are liable to change. Where registration is required ...
Prescribing Information
... the prophylaxis of organ rejection in kidney transplant patients in combination with other immunosuppressants (1) Limitation of Use: Not interchangeable or substitutable with other tacrolimus products (1, 5.4) ----------------------DOSAGE AND ADMINISTRATION---------------------- Take consistently ...
... the prophylaxis of organ rejection in kidney transplant patients in combination with other immunosuppressants (1) Limitation of Use: Not interchangeable or substitutable with other tacrolimus products (1, 5.4) ----------------------DOSAGE AND ADMINISTRATION---------------------- Take consistently ...
Pravachol
... effect of pravastatin therapy on coronary atherosclerosis was assessed by coronary angiography in patients with coronary disease and moderate hypercholesterolaemia (baseline LDL-C range =3.4 4.9 mmol/L). In this double-blind, multicentre, controlled clinical trial, in which 408 patients were randomi ...
... effect of pravastatin therapy on coronary atherosclerosis was assessed by coronary angiography in patients with coronary disease and moderate hypercholesterolaemia (baseline LDL-C range =3.4 4.9 mmol/L). In this double-blind, multicentre, controlled clinical trial, in which 408 patients were randomi ...
Expert Opin. Ther. Pat. 2016, 27, 179–189
... Introduction: Drug conjugates are trend topics in Chemical Biology. These entities are an emerging class of highly potent biopharmaceutical drugs, best known in the field of oncology, that have been also designed as a targeted therapy/diagnosis for the treatment/prevention of several bacterial disea ...
... Introduction: Drug conjugates are trend topics in Chemical Biology. These entities are an emerging class of highly potent biopharmaceutical drugs, best known in the field of oncology, that have been also designed as a targeted therapy/diagnosis for the treatment/prevention of several bacterial disea ...
PR OZA C - Family Guardian
... cancer, Chronic Fatigue Syndrome, and fibromyalgia since these serotonergic drugs have become so popular and I relate it directly to the effects of these serotonergic drugs. As the serotonergic-induced sleepwalk nightmares are acted out by these patients, the death toll has continued to climb drasti ...
... cancer, Chronic Fatigue Syndrome, and fibromyalgia since these serotonergic drugs have become so popular and I relate it directly to the effects of these serotonergic drugs. As the serotonergic-induced sleepwalk nightmares are acted out by these patients, the death toll has continued to climb drasti ...
Bad Pharma
Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.