Antiviral drugs for cytomegalovirus diseases
... In high-risk patients without symptomatic CMV disease, two common strategies of disease management are prophylactic and preemptive therapy, both of which are designed to prevent CMV disease. In the prophylactic approach, therapy is usually initiated at the time of stem cell engraftment or solid orga ...
... In high-risk patients without symptomatic CMV disease, two common strategies of disease management are prophylactic and preemptive therapy, both of which are designed to prevent CMV disease. In the prophylactic approach, therapy is usually initiated at the time of stem cell engraftment or solid orga ...
Guidelines Update: Obesity - South Carolina Society of Health
... American College of Cardiology/American Heart Association/The Obesity Society (2013) • Pharmacotherapy is indicated for patients who do not achieve goals after the first 6 months. • Weigh the risks versus benefits of each pharmacologic option. • If therapeutic goal is achieved with the pharmacol ...
... American College of Cardiology/American Heart Association/The Obesity Society (2013) • Pharmacotherapy is indicated for patients who do not achieve goals after the first 6 months. • Weigh the risks versus benefits of each pharmacologic option. • If therapeutic goal is achieved with the pharmacol ...
[FDA Approved Labeling for Zoloft® for the Treatment of Social... Attachment to FDA Approval Letter for NDA 19-839/S-045]
... mean reduction of approximately 7 points on the CYBOCS total score which was significantly greater than the 3 point reduction for placebo patients. Analyses for age and gender effects on outcome did not suggest any differential responsiveness on the basis of age or sex. In a longer-term study, patie ...
... mean reduction of approximately 7 points on the CYBOCS total score which was significantly greater than the 3 point reduction for placebo patients. Analyses for age and gender effects on outcome did not suggest any differential responsiveness on the basis of age or sex. In a longer-term study, patie ...
SPORANOX® Oral Solution
... relapse in the maintenance period using the Kaplan-Meier analysis of survival was greater than 108 and 94 days respectively. The global evaluation and time to relapse for itraconazole 100 mg b.i.d. and fluconazole 100 mg o.d. were equivalent. In the other double-blind study, itraconazole 100 mg b.i. ...
... relapse in the maintenance period using the Kaplan-Meier analysis of survival was greater than 108 and 94 days respectively. The global evaluation and time to relapse for itraconazole 100 mg b.i.d. and fluconazole 100 mg o.d. were equivalent. In the other double-blind study, itraconazole 100 mg b.i. ...
Abrams v Bute - New York State Unified Court System
... who prescribed and administered drugs” (David B. Brushwood, The Pharmacist’s Duty to Warn: Toward a Knowledge-based Model of Professional Responsibility, 40 Drake L Rev 1, 5 n 16 [1991]). However, the specific role played by pharmacists in the distribution of prescription medication has fluctuated i ...
... who prescribed and administered drugs” (David B. Brushwood, The Pharmacist’s Duty to Warn: Toward a Knowledge-based Model of Professional Responsibility, 40 Drake L Rev 1, 5 n 16 [1991]). However, the specific role played by pharmacists in the distribution of prescription medication has fluctuated i ...
Zyban SPC (Mar 15)
... Therefore 150 mg once a day is the recommended dose in patients with renal impairment, as bupropion and its active metabolites may accumulate to a greater extent than usual (see sections 4.2 and 5.2). The patient should be closely monitored for possible undesirable effects that could indicate high d ...
... Therefore 150 mg once a day is the recommended dose in patients with renal impairment, as bupropion and its active metabolites may accumulate to a greater extent than usual (see sections 4.2 and 5.2). The patient should be closely monitored for possible undesirable effects that could indicate high d ...
Medication noncompliance in patients over the age of 65: risk factors
... Another intentional medication noncompliance factor occurs when a patient does not understand that a medication is important. Even though the physician specifically instructed the patient to take the medication daily, they may take the medication every other day or even only once a week. Case Manage ...
... Another intentional medication noncompliance factor occurs when a patient does not understand that a medication is important. Even though the physician specifically instructed the patient to take the medication daily, they may take the medication every other day or even only once a week. Case Manage ...
A prospective clinical study of theophylline safety in 3810
... incidence and severity of such adverse events, we studied elderly patients who received sustainedrelease theophylline in the present large-scale prospective study. ...
... incidence and severity of such adverse events, we studied elderly patients who received sustainedrelease theophylline in the present large-scale prospective study. ...
Pyridoxine hydrochloride attenuate and decrease the depressant
... (CFI) threshold which is not affected by meclizine (p>0.05) table 2 and figure 2. Table (2): Effects of single oral dose of meclizine(25mg) on psychomotor performances ...
... (CFI) threshold which is not affected by meclizine (p>0.05) table 2 and figure 2. Table (2): Effects of single oral dose of meclizine(25mg) on psychomotor performances ...
Neural and psychological mechanisms underlying compulsive drug
... Introduction Many people take drugs that are addictive and do so for different reasons, in different ways and in different contexts, for example the social drinking of alcohol, which is acceptable in some but not all societies, or the more solitary intravenous use of drugs such as heroin. These drug ...
... Introduction Many people take drugs that are addictive and do so for different reasons, in different ways and in different contexts, for example the social drinking of alcohol, which is acceptable in some but not all societies, or the more solitary intravenous use of drugs such as heroin. These drug ...
Academic Detailing Service - Faculty of Medicine
... Aliskiren has been found to be as effective in lowering BP as ACEIs, ARBs, and HCTZ. ...
... Aliskiren has been found to be as effective in lowering BP as ACEIs, ARBs, and HCTZ. ...
OSAFLEX 1178 mg powder for oral solution, sachet ENG
... symptoms (especially pain relief) may not be experienced until after several weeks of treatment and in some cases even longer. If no relief of symptoms is experienced after 2-3 months, continued treatment with glucosamine should be re-evaluated. Osaflex should be taken at meals. Additional informati ...
... symptoms (especially pain relief) may not be experienced until after several weeks of treatment and in some cases even longer. If no relief of symptoms is experienced after 2-3 months, continued treatment with glucosamine should be re-evaluated. Osaflex should be taken at meals. Additional informati ...
Addiction (1999) 94(5), 665-674
... for a minimum of 6 months, as stipulated in the inclusion criteria, and had been on the same dose for at least 4 weeks before participating in the study. Participants' reported illicit drug use was fairly typical of this treatment population; 72% of participants reported using at least one illicit d ...
... for a minimum of 6 months, as stipulated in the inclusion criteria, and had been on the same dose for at least 4 weeks before participating in the study. Participants' reported illicit drug use was fairly typical of this treatment population; 72% of participants reported using at least one illicit d ...
effects of cytochrome p450 enzyme inhibitors on the
... Cytochrome P450 (CYP) enzymes play a pivotal role in the metabolism of many drugs. Inhibition of CYP enzymes usually increases the plasma concentrations of their substrate drugs and can thus alter the safety and efficacy of these drugs. The metabolism of many widely used nonsteroidal anti-inflammato ...
... Cytochrome P450 (CYP) enzymes play a pivotal role in the metabolism of many drugs. Inhibition of CYP enzymes usually increases the plasma concentrations of their substrate drugs and can thus alter the safety and efficacy of these drugs. The metabolism of many widely used nonsteroidal anti-inflammato ...
GHB - Center for Substance Abuse Research
... as parties, clubs, and raves, for its intoxicating, euphoric, and sedative effects. Because of these effects, GHB can be lethal when combined with alcohol or other depressants,1 and as a result, has been implicated in many cases of ‘date rape’ and also labeled as a ‘club drug.’ These associations ma ...
... as parties, clubs, and raves, for its intoxicating, euphoric, and sedative effects. Because of these effects, GHB can be lethal when combined with alcohol or other depressants,1 and as a result, has been implicated in many cases of ‘date rape’ and also labeled as a ‘club drug.’ These associations ma ...
La néoténie - Physiologie et Thérapeutique Ecole Véto Toulouse
... As demonstrated by both theoretical and literature experimentation, rats had no significance in predicting human PK parameters as long as the body weight of the rat is not the smallest in the species used in the allometric relationship. ...
... As demonstrated by both theoretical and literature experimentation, rats had no significance in predicting human PK parameters as long as the body weight of the rat is not the smallest in the species used in the allometric relationship. ...
Medications – What to Know BEFORE Transplant Anti
... You are not required to join. You must volunteer in order to be able to take part in a clinical trial. Making the decision to take part in a clinical trial is important. A decision should be made after you have full knowledge of what is involved. Taking part in a clinical trial may or may not improv ...
... You are not required to join. You must volunteer in order to be able to take part in a clinical trial. Making the decision to take part in a clinical trial is important. A decision should be made after you have full knowledge of what is involved. Taking part in a clinical trial may or may not improv ...
St John`s wort versus placebo in obsessive
... The % of SJW patients rated ‘much’ or ‘very much’ improved was 17.9%; compared to rates of 42% in the open-label trial, 38% for fluoxetine, 43% for fluvoxamine (Kobak et al., 1998). The numerically larger response on placebo suggests that the results are not due to a type II error. ...
... The % of SJW patients rated ‘much’ or ‘very much’ improved was 17.9%; compared to rates of 42% in the open-label trial, 38% for fluoxetine, 43% for fluvoxamine (Kobak et al., 1998). The numerically larger response on placebo suggests that the results are not due to a type II error. ...
Drug-resistant TB: surveillance and response: supplement to global
... Data on levels of TB drug resistance available for countries with 95% of world’s population AND TB CASES By 2014, data on drug resistance were available for 144 countries, which collectively have 95% of the world’s population and TB cases. This shows impressive progress: in the period 1994−1999, dat ...
... Data on levels of TB drug resistance available for countries with 95% of world’s population AND TB CASES By 2014, data on drug resistance were available for 144 countries, which collectively have 95% of the world’s population and TB cases. This shows impressive progress: in the period 1994−1999, dat ...
periostat product monograph
... can have toxic effects on the developing fetus (often related to retardation of skeletal development). Evidence of embryotoxicity has also been noted in animals treated early in pregnancy. If any tetracyclines are used during pregnancy, or if the patient becomes pregnant while taking this drug, the ...
... can have toxic effects on the developing fetus (often related to retardation of skeletal development). Evidence of embryotoxicity has also been noted in animals treated early in pregnancy. If any tetracyclines are used during pregnancy, or if the patient becomes pregnant while taking this drug, the ...
6.4 a brief introduction about loratadine [10][11]
... Analytical methods are essential to characterize drug substances and drug products composition during all stages of pharmaceutical development. For routine analytical purpose it is always necessary to establish methods capable of analyzing large number of samples in a short time period with high acc ...
... Analytical methods are essential to characterize drug substances and drug products composition during all stages of pharmaceutical development. For routine analytical purpose it is always necessary to establish methods capable of analyzing large number of samples in a short time period with high acc ...
Lupin Launches InspiraChamber Anti
... development company InspiRX Inc. (InspiRX). The agreement grants Lupin exclusive rights to promote, distribute and market InspiraChamber® VHC in the United States. In 2010, the National Centers for Disease Control and Prevention (CDC) reported that 8.4% of Americans had been diagnosed with asthma, a ...
... development company InspiRX Inc. (InspiRX). The agreement grants Lupin exclusive rights to promote, distribute and market InspiraChamber® VHC in the United States. In 2010, the National Centers for Disease Control and Prevention (CDC) reported that 8.4% of Americans had been diagnosed with asthma, a ...
A Position Paper - American College of Physicians
... are experienced immediately. Studies have found that patients prefer the immediate effect on symptoms that occurs after smoking marijuana (32, 33). Therefore, there may be some patient populations (e.g., cancer patients who experience nausea and vomiting during chemotherapy) for whom the inhalation ...
... are experienced immediately. Studies have found that patients prefer the immediate effect on symptoms that occurs after smoking marijuana (32, 33). Therefore, there may be some patient populations (e.g., cancer patients who experience nausea and vomiting during chemotherapy) for whom the inhalation ...
Bad Pharma
Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.