
BIO100 KEY CONCEPTS and TIDEPOOLS-
... The Natural Environment = Ecosystems: An interacting unit of living and non-living components ...
... The Natural Environment = Ecosystems: An interacting unit of living and non-living components ...
Species Relationships PPT
... What is a Habitat? • Each organism also has a habitat. A habitat is the place where an organism most often lives. • Example: Bats live in dark, moist locations, so their habitat would be a place like a cave or under a bridge. ...
... What is a Habitat? • Each organism also has a habitat. A habitat is the place where an organism most often lives. • Example: Bats live in dark, moist locations, so their habitat would be a place like a cave or under a bridge. ...
Lecture 4
... Case study: Painlessness in Humans • Broad-spectrum sodium channel blockers are used as local anaesthetics, but they are not suitable for long-term pain management as they cause complete numbness and can have serious side-effects over time. • Opioid painkillers such as morphine are highly effective ...
... Case study: Painlessness in Humans • Broad-spectrum sodium channel blockers are used as local anaesthetics, but they are not suitable for long-term pain management as they cause complete numbness and can have serious side-effects over time. • Opioid painkillers such as morphine are highly effective ...
ECOLOGY- (population growth) notes
... 5. In an ecosystem, there are limited amounts of food, water, and shelter. Organisms that share the same habitat often have adaptations that enable them to reduce competition. 6. Predators have adaptations that help them catch and kill their prey. Some examples are a cheetah’s speed, and the ability ...
... 5. In an ecosystem, there are limited amounts of food, water, and shelter. Organisms that share the same habitat often have adaptations that enable them to reduce competition. 6. Predators have adaptations that help them catch and kill their prey. Some examples are a cheetah’s speed, and the ability ...
Autonomní nervový systém
... – nasal decongestion (reactive hyperaemia with increased secretion) – bronchodilatans – metamphetamine synthesis (”pervitin") ...
... – nasal decongestion (reactive hyperaemia with increased secretion) – bronchodilatans – metamphetamine synthesis (”pervitin") ...
Pharmacodynamics (08)
... Making the assumption that an effect of a drug is dependent on the number of receptors occupied, it can be stated that at binding equilibrium, the drug effect would be also be constant. Affinity describes the strength of binding to receptors, Drugs that bind with great avidity to the receptors are s ...
... Making the assumption that an effect of a drug is dependent on the number of receptors occupied, it can be stated that at binding equilibrium, the drug effect would be also be constant. Affinity describes the strength of binding to receptors, Drugs that bind with great avidity to the receptors are s ...
02 02
... Adrenaline(epinephrine) was only thought to be the neurotransmitter in the adrenergic nervous system 1940, nor adrenaline (nor epinephrine, NE) was identified with true neurotransmitter at Terminus of the sympathetic nervous system. ...
... Adrenaline(epinephrine) was only thought to be the neurotransmitter in the adrenergic nervous system 1940, nor adrenaline (nor epinephrine, NE) was identified with true neurotransmitter at Terminus of the sympathetic nervous system. ...
Activity 1.5
... million species are known, but this is thought to be a significant underestimate of the total number of species. Every year, thousands of new species are discovered. Biologists use characteristics of each newly discovered species to classify organisms having similar characteristics. A classification ...
... million species are known, but this is thought to be a significant underestimate of the total number of species. Every year, thousands of new species are discovered. Biologists use characteristics of each newly discovered species to classify organisms having similar characteristics. A classification ...
Chapter 5 Over the counter drugs[1].
... 1. Liquorice or plant extract: They are irritants of the gastric mucosa and they stimulate the afferent fibers of the vagus nerve to the medulla. This results in increased parasympathetic stimulation of the efferent fiber of the vagus nerve back to the stomach. Vagal stimulation to the lungs increa ...
... 1. Liquorice or plant extract: They are irritants of the gastric mucosa and they stimulate the afferent fibers of the vagus nerve to the medulla. This results in increased parasympathetic stimulation of the efferent fiber of the vagus nerve back to the stomach. Vagal stimulation to the lungs increa ...
milk thistle (milkthis-ul) - DavisPlus
... lizing enzyme cytochrome P450 3A4. Interactions have not been reported in humans, but milk thistle should be used cautiously with other drugs metabolized by 3A4, such as cyclosporine, carbamazepine, HMG-CoA inhibitors, ketoconazole, and alprazolam. Natural-Natural Products: None known. ...
... lizing enzyme cytochrome P450 3A4. Interactions have not been reported in humans, but milk thistle should be used cautiously with other drugs metabolized by 3A4, such as cyclosporine, carbamazepine, HMG-CoA inhibitors, ketoconazole, and alprazolam. Natural-Natural Products: None known. ...
181lec11
... NMDA receptors at critical stages in development activates programed cell death. See with PCP, ketamine (special K) and ethanol ...
... NMDA receptors at critical stages in development activates programed cell death. See with PCP, ketamine (special K) and ethanol ...
Significant Drug Interactions with Tuberculosis Medications
... › RD is a 49 yo BM who was started on Rifampin for LTBI. One month into treatment RD called TB clinic to report BP of 180/100 and severe headache. He was on amlodipine(Norvasc) at the time and had controlled HTN ...
... › RD is a 49 yo BM who was started on Rifampin for LTBI. One month into treatment RD called TB clinic to report BP of 180/100 and severe headache. He was on amlodipine(Norvasc) at the time and had controlled HTN ...
Interpretive Context and Application of the Biological Condition
... a balance between human values and ecological impacts. Attribute VII: Organism Condition Organism condition is an element of ecosystem function, expressed at the level of the individual. It has been listed as a separate attribute because it is readily observed in the field for certain assemblages (e ...
... a balance between human values and ecological impacts. Attribute VII: Organism Condition Organism condition is an element of ecosystem function, expressed at the level of the individual. It has been listed as a separate attribute because it is readily observed in the field for certain assemblages (e ...
Pharmacology II – Respiratory and Oxygenation
... COPD. At his last office visit, the MD added ipratropium (Atrovent) and beclomethasone (Vanceril) to his betaadrenergic (Alupent) inhaler. He visits the office complaining of severe dyspnea. You quickly grab his Atrovent inhaler to administer a PRN dose and try to get him to relax. What drug error h ...
... COPD. At his last office visit, the MD added ipratropium (Atrovent) and beclomethasone (Vanceril) to his betaadrenergic (Alupent) inhaler. He visits the office complaining of severe dyspnea. You quickly grab his Atrovent inhaler to administer a PRN dose and try to get him to relax. What drug error h ...
Conformational aspects of drug-DNA interactions: Studies on
... functionally organized DNA was also studied. Lower binding affinities and modified spectral responsesareindicativeofdifferent drug-DNA complexation patternsinthiscase. The results of these studies allow a better understanding of drug-nucleic acid interactions at a molecular level. Keywords. Chemothe ...
... functionally organized DNA was also studied. Lower binding affinities and modified spectral responsesareindicativeofdifferent drug-DNA complexation patternsinthiscase. The results of these studies allow a better understanding of drug-nucleic acid interactions at a molecular level. Keywords. Chemothe ...
Respiratory Care Pharmacology
... choice for the treatment of asthma. Methyxanthines (use is controversial) Oral or IV use if admitted for acute asthma attack ...
... choice for the treatment of asthma. Methyxanthines (use is controversial) Oral or IV use if admitted for acute asthma attack ...
Adrenergic Drugs
... heart block For asthma (rarely) ADR: Tachycardia Arrhythmia Hypotension ...
... heart block For asthma (rarely) ADR: Tachycardia Arrhythmia Hypotension ...
Name: Biology Quarter Test 1 Review Scientific Method What is a
... Population - a group of organisms, all the same species, living in the same place at the same time; populations also have the ability to interbreed Community - a group of interacting populations living in the same place at the same time Ecosystem - a group of interacting communities living in the sa ...
... Population - a group of organisms, all the same species, living in the same place at the same time; populations also have the ability to interbreed Community - a group of interacting populations living in the same place at the same time Ecosystem - a group of interacting communities living in the sa ...
Epinephrine
... inc. blood return to heart, inc. circulation, inc. BP 2. Alpha-2 = inhibits release of norepinephrine dec. in vasoconstriction, dec. BP 3. Beta-1 = inc. in heart rate & force on contraction 4. Beta-2 = relaxation of smooth muscle in bronchi, ...
... inc. blood return to heart, inc. circulation, inc. BP 2. Alpha-2 = inhibits release of norepinephrine dec. in vasoconstriction, dec. BP 3. Beta-1 = inc. in heart rate & force on contraction 4. Beta-2 = relaxation of smooth muscle in bronchi, ...
What is Modeling?
... Soft link – PK+PD data – temporal delay – Indirect link models are soft link because they must be characterized using PK and PD data. Hard link – PK data + in vitro studies (e.g. binding affinities) ...
... Soft link – PK+PD data – temporal delay – Indirect link models are soft link because they must be characterized using PK and PD data. Hard link – PK data + in vitro studies (e.g. binding affinities) ...
Biomarker Identification and Assay Development | Charles River
... The following illustrations demonstrate the breadth of Charles River’s biomarker identification and validation capabilities as applied in an oncology project. Using a validated tool compound, we were able to show significant changes to primary and secondary pathway phosphoproteins (Figure 1). This s ...
... The following illustrations demonstrate the breadth of Charles River’s biomarker identification and validation capabilities as applied in an oncology project. Using a validated tool compound, we were able to show significant changes to primary and secondary pathway phosphoproteins (Figure 1). This s ...
Dr. Brown (Outlined) - Website of Neelay Gandhi
... o Chlorpromazine blocks DA receptors o By 1975, there were many anti-psychotic drugs (like chlorpromazine) o Measured the binding to DA receptors as well as the clinical potency Measure amount of membrane ~>add drug, shake and rinse ~> add radioactive dopamine, shake, rinse ~> measure radioactivit ...
... o Chlorpromazine blocks DA receptors o By 1975, there were many anti-psychotic drugs (like chlorpromazine) o Measured the binding to DA receptors as well as the clinical potency Measure amount of membrane ~>add drug, shake and rinse ~> add radioactive dopamine, shake, rinse ~> measure radioactivit ...
Toxicodynamics

Toxicodynamics, termed pharmacodynamics in pharmacology, describes the dynamic interactions of a toxicant with a biological target and its biological effects. A biological target, also known as the site of action, can be binding proteins, ion channels, DNA, or a variety of other receptors. When a toxicant enters an organism, it can interact with these receptors and produce structural or functional alterations. The mechanism of action of the toxicant, as determined by a toxicant’s chemical properties, will determine what receptors are targeted and the overall toxic effect at the cellular level and organismal level.Toxicants have been grouped together according to their chemical properties by way of quantitative structure-activity relationships (QSARs), which allows prediction of toxic action based on these properties. endocrine disrupting chemicals (EDCs) and carcinogens are examples of classes of toxicants that can act as QSARs. EDCs mimic or block transcriptional activation normally caused by natural steroid hormones. These types of chemicals can act on androgen receptors, estrogen receptors and thyroid hormone receptors. This mechanism can include such toxicants as dichlorodiphenyltrichloroethane (DDE) and polychlorinated biphenyls (PCBs). Another class of chemicals, carcinogens, are substances that cause cancer and can be classified as genotoxic or nongenotoxic carcinogens. These categories include toxicants such as polycyclic aromatic hydrocarbon (PAHs) and carbon tetrachloride (CCl4). The process of toxicodynamics can be useful for application in environmental risk assessment by implementing toxicokinetic-toxicodynamic (TKTD) models. TKTD models include phenomenas such as time-varying exposure, carry-over toxicity, organism recovery time, effects of mixtures, and extrapolation to untested chemicals and species. Due to their advantages, these types of models may be more applicable for risk assessment than traditional modeling approaches.