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Viral Persistence
Viral Persistence

... Reovirus is a lytic virus but can be induced to cause persistent infections in cell culture by co-infecting cultures with a lytic wild type virus (Type 2 wt) and a temperature sensitive variant (Type 3 ts). The virus isolated late after persistent infection is a reassortant carrying the genes of the ...
Bloodborne Pathogens
Bloodborne Pathogens

... blood, or other potentially infectious material such as certain bodily fluids (semen, breast milk, etc.) or tissues. ...
Unit E Master Outline
Unit E Master Outline

... itself against foreign material, and instead, the antibodies formed irritate certain body cells.  An abnormal response to a drug or allergen.  An ALLERGEN is an antigen that causes allergic responses. (Examples of allergens – ragweed, penicillin, bee stings, foods, etc.) ANAPHYLAXIS  severe, some ...
Immune Serum Increases Arenavirus Replication in Monocytes
Immune Serum Increases Arenavirus Replication in Monocytes

... facilitate infection and replication of the arenaviruses, Pichinde virus (PV) and Lassa fever virus (LFV). When high dilutions of PV-immune serum were added to cultures simultaneously with PV inoculum, virus replication was dramatically (1000-fold) increased. Low dilutions of this antiserum neutrali ...
Immune Serum Increases Arenavirus Replication in Monocytes
Immune Serum Increases Arenavirus Replication in Monocytes

... facilitate infection and replication of the arenaviruses, Pichinde virus (PV) and Lassa fever virus (LFV). When high dilutions of PV-immune serum were added to cultures simultaneously with PV inoculum, virus replication was dramatically (1000-fold) increased. Low dilutions of this antiserum neutrali ...
a. Herpes Simplex Type 1
a. Herpes Simplex Type 1

... 5. Genomic concatemers are cleaved and packaged into preassembled capsids in the nucleus 6. Three classes of mRNAs produced 7. Coordinated gene expression 8. After synthesis capsid proteins are transported to the nucleus where their assembly with DNA takes place ...
Virus - District 128 Moodle
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...  Yellow fever, West Nile ...
The Drug War: Fueling the HIV/AIDS Pandemic
The Drug War: Fueling the HIV/AIDS Pandemic

... and the number of AIDS cases are markedly higher in correctional settings than among the general population. In the U.S., up to 25 percent of all HIVinfected people are estimated to cycle through correctional facilities each year.2 Incarceration is associated with higher risks of unsafe injecting dr ...
owenprotistanotes - Kowenscience.com
owenprotistanotes - Kowenscience.com

... a capsid, which is formed from a number of individual protein molecules called capsomeres,' ...
owenprotistanotes - Kowenscience.com
owenprotistanotes - Kowenscience.com

... a capsid, which is formed from a number of individual protein molecules called capsomeres,' ...
Common Sexually Transmitted Infections
Common Sexually Transmitted Infections

... (sexual intercourse), sharing needles, razors, toothbrushes, etc. of infected person. A pregnant woman can pass the virus to her child. ...
1 To Catch a Virus John Booss and Marilyn J. August, ASM Press
1 To Catch a Virus John Booss and Marilyn J. August, ASM Press

... The title of this book, To Catch a Virus, refers to the capture and identification of viruses. It is a history of diagnostic virology inspired by Gueth-Djen (Edith) Hsiung, with whom both of the authors trained. John Booss, a retired neurologist, gathered much of the information for this book. Marily ...
Virus Structure Lecture PowerPoint
Virus Structure Lecture PowerPoint

... nucleic acid and means of attachment to host’s cells.  Composed of protein subunits called capsomeres. ...
Viral Pathogens
Viral Pathogens

... • typically produce 1000s to 100,000s per infected cell • often destroy (lyse) the host cell as a result of infection – some viruses: host cell survives to shed viruses over time ...
Strategies for Health Insurers to Optimize Coverage for People with
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... care. If prior authorization is employed for antiretrovirals, we strongly urge reference to the HHS treatment guidelines and authorization of coverage for 12-month periods. 5) Institute Effective Pharmacy Practices: Uninterrupted access to HIV medications is critical to treatment success. For restr ...
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... New TB cases are driven by the reservoir of latently infected people. If we want to stop active TB cases, we need to eliminate this reservoir of infection. ...
Chapter 6 An Introduction to Viruses
Chapter 6 An Introduction to Viruses

... translation of a viral gene to make RNA-dependent RNA polymerase. The polymerase uses the picornavirus RNA template to make (–) strand RNA, which then serves as a template for other viral mRNAs, as well as progeny genomic RNA, which is replicated in virus-induced vesicles from the endoplasmic reticu ...
Immune deficiency syndromes
Immune deficiency syndromes

... number of B cells in blood  Transient inability to produce IgG  May be due to deficiency in number and function of helper T cells ...
Construction and in vivo infection of a new simian
Construction and in vivo infection of a new simian

... (Kuwata et al., 1995; Li et al., 1992; Shibata et al., 1991). The SHIVs containing the env gene of HIV-1 were shown to be useful for evaluating the efficacy of anti-HIV-1 vaccine candidates targeting Env proteins by using them as challenge viruses for vaccinated monkeys (Ui et al., 1999). Although t ...
The Chain of Infection
The Chain of Infection

... -the person that the pathogen enters A susceptible person is someone at higher risk for developing an infection ...
Lecture GuideViruses(Ch13)–7e
Lecture GuideViruses(Ch13)–7e

... proof-reading ability of DNA polymerase so it is common that mistakes in the sequence are made. If the sequence changes due to mistakes or point mutations, this often results in a subtle change in the protein and are called antigenetic drifts. The influenza virus is transferred from one person to an ...
HEPATITIS: Etiology, Differential and Transmission
HEPATITIS: Etiology, Differential and Transmission

... - HBsAg – person has virus and is infectious; virus is replicating; can be chronic state; don’t know when person got it - Anti HBs - immunity to HBV; not found in chronic carriers - Anti HBc - IgG; not a neutralizing Ab - indicates past or active infection both in immune and carrier If IgM indicates ...
Gapped dsDNA genomes
Gapped dsDNA genomes

... Gene  products  involved  in  membrane  biosynthesis   Gene  products  involved  in  energy  producWon   Complete  protein  synthesis  systems   Centromeres  or  telomeres     Enzymes  to  replicate  the  viral  genome ...
Bovine viral diarrhoea virus: virulence factors and improved control
Bovine viral diarrhoea virus: virulence factors and improved control

... clinical signs of infection. In most countries with intensive cattle rearing the BVD prevalence is high, and thus considered to be a major loss-inducing endemic viral disease of cattle. Based on antigenic and genetic criteria, the causative virus has been classified as two distinct species (types 1 ...
Rotavirus
Rotavirus

... •Has been at the root of several epidemics or outbreaks of gastroenteritis across North America in hospital emergency rooms, schools and even on cruise ships •There is a group of similar or related viruses that are referred to as Norwalk-like viruses or agents. •Can infect people of any age and usua ...
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HIV



The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and acquired immunodeficiency syndrome (AIDS). AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells.HIV infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells. HIV infection leads to low levels of CD4+ T cells through a number of mechanisms, including apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections.
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