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Vaccines for emerging infections
Vaccines for emerging infections

... longer occurred. The WHO acknowledged that prevention of HPAI H5N1 avian influenza in humans is best achieved by controlling infection in poultry. The WHO supported FAO and OIE recommendations that control strategies for HPAI H5N1 should consider vaccination of poultry (81). However, vaccination doe ...
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Reference clustering - Analyzing Unknown Binaries

... is represented by the set of malware samples to which it was assigned by AV engines. We use Jaccard Index as a distance function. We then simply perform single-linkage hierarchical clustering on the labels with a threshold of 0.5. The result of this clustering is a mapping between engine-specific vi ...
Rift Valley Fever
Rift Valley Fever

... The natural vertebrate reservoir of the Rift Valley fever virus has not yet been precisely identified but is suspected to be one or several wild ungulates. The virus remains in a silent enzootic cycle for many years, and then, during a period of heavy rainfall, it explodes in epizootics of great mag ...
Contagious diseases
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... 1997 CSF outbreak in The Netherlands could have cost less than the culling of 11 million pigs provided that vaccinated pigs were not destroyed but were slaughtered commercially to return to the status of freedom without vaccination. It is clear, however, that for contagious diseases that have a high ...
Multiplex PCR in diagnosis and characterization of bovine viral
Multiplex PCR in diagnosis and characterization of bovine viral

... disease, haemorrhagic syndrome and recently reported dermatitis 4,5. Persistent life-long infections or carrier status can occur when the foetus is infected in the first trimester of gestation. Because carrier animals are constantly viraemic and continuously shed and maintain the virus, their identi ...
PowerPoint file
PowerPoint file

...  Also divided by antigenic differences in protein coats:  Type A → mammals and birds (most severe and extensive); currently most common antigenic variants of influenza A virus: H1N1 and H3N2  Types B and C → humans only  Viral isolates identified by HI and IF testing with monoclonal antibodies C ...
Microbial Diseases of the Respiratory System
Microbial Diseases of the Respiratory System

...  Also divided by antigenic differences in protein coats:  Type A → mammals and birds (most severe and extensive); currently most common antigenic variants of influenza A virus: H1N1 and H3N2  Types B and C → humans only  Viral isolates identified by HI and IF testing with monoclonal antibodies C ...
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From obscurity, to emergency, to enduring public health threat

... to a devastating birth defect. In February 2016, following the World Health Organization’s declaration that the virus and the accompanying impacts of microcephaly and Guillain-Barré syndrome constituted an international public health emergency, the Obama Administration asked Congress to allocate $1. ...
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Proposal to Reduce the Post Arrival Quarantine Period for Imported

... Infectious bursal disease (IBD) is an acute, contagious viral infection, which causes immunosuppression in young chicks, and disease and mortality in 3- to 6-week-old chickens (Lukert and Saif 1997; van den Berg et al. 2000). The virus infects actively dividing B lymphocytes within the bursa of Fabr ...
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  Infection prevention and control during health care for confirmed, probable, or  suspected cases of pandemic (H1N1) 2009 virus infection and influenza‐like 
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Enterovirus D68 (EV 68)
Enterovirus D68 (EV 68)

... respiratory illness, diarrhea, rash and even meningitis and encephalitis.  This particular virus was first  identified in California in 1962.  It has been circulating worldwide for several years, causing mild to  severe respiratory illness.    ...
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... QUANDHIP project activation in response to the Ebola outbreak in West Africa (i) updated and disseminated data about diagnostic capabilities for Filovirus in QUANDHIP laboratories (BSL4 and skilled BSL3); (ii) developed directory of contact persons for laboratories with EVD diagnostic capabilities; ...
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... are the free roaming entire males that commonly fight with other cats, or cats that live in large population numbers whereby the virus can pass from one to another easily. Young cats, particularly less than six months old, are especially vulnerable. ...
Rapid Point of Care Molecular Diagnostic Test for Ebola
Rapid Point of Care Molecular Diagnostic Test for Ebola

... transmission cycle. This requires availability of diagnostic tests to rapidly confirm or discard suspected cases to help in clinical decisions and to facilitate early detection of cases. During the current Ebola outbreak in West Africa, efforts to break the transmission cycle was hampered by cumbers ...
Swine Influenza A (H1N1 Virus): A Pandemic Disease
Swine Influenza A (H1N1 Virus): A Pandemic Disease

... subtypes became possible; this allowed accurate diagnosis of transmission to humans. Since then, 50 confirmed transmissions have been recorded; rarely these strains of swine flu can pass from human to human. In humans, the symptoms of swine flu are similar to those of influenza and of influenza-like ...
Humans Meet Ebola Virus in Africa, 1976
Humans Meet Ebola Virus in Africa, 1976

... included suggestive epidemiology in patterns of spread within rooms and between rooms in the quarantine facility, high concentrations of virus in nasal and oropharyngeal secretions, and ultrastructural visualization of abundant virus particles in alveoli [17, 50]. However, this is far from saying t ...
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Influenza A virus



Influenza A virus causes influenza in birds and some mammals, and is the only species of influenza virus A. Influenza virus A is a genus of the Orthomyxoviridae family of viruses. Strains of all subtypes of influenza A virus have been isolated from wild birds, although disease is uncommon. Some isolates of influenza A virus cause severe disease both in domestic poultry and, rarely, in humans. Occasionally, viruses are transmitted from wild aquatic birds to domestic poultry, and this may cause an outbreak or give rise to human influenza pandemics.Influenza A viruses are negative-sense, single-stranded, segmented RNA viruses.The several subtypes are labeled according to an H number (for the type of hemagglutinin) and an N number (for the type of neuraminidase). There are 18 different known H antigens (H1 to H18) and 11 different known N antigens (N1 to N11). H17 was isolated from fruit bats in 2012. H18N11 was discovered in a Peruvian bat in 2013.Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.A filtered and purified influenza A vaccine for humans has been developed, and many countries have stockpiled it to allow a quick administration to the population in the event of an avian influenza pandemic. Avian influenza is sometimes called avian flu, and colloquially, bird flu. In 2011, researchers reported the discovery of an antibody effective against all types of the influenza A virus.
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