Pegvisomant, a Growth Hormone-Specific Antagonist, Undergoes
... (15). The observation that B2036 and pegvisomant show greater fluorescence at the cell surface may relate to a different conformation of the ligand-GHR complex delaying triggering of internalization and increasing residence of antagonist at the cell surface. We accept that all of our data relate to ...
... (15). The observation that B2036 and pegvisomant show greater fluorescence at the cell surface may relate to a different conformation of the ligand-GHR complex delaying triggering of internalization and increasing residence of antagonist at the cell surface. We accept that all of our data relate to ...
Molecular regulation of the diatom cell cycle
... dynamics. Nutrient limitation at the end of a diatom bloom period is often accompanied by switches in the diatom life cycle phase from vegetative division to spore formation or sexual reproduction (Smetacek, 2012). The major limiting nutrients of primary production in the oceans are nitrogen, phosph ...
... dynamics. Nutrient limitation at the end of a diatom bloom period is often accompanied by switches in the diatom life cycle phase from vegetative division to spore formation or sexual reproduction (Smetacek, 2012). The major limiting nutrients of primary production in the oceans are nitrogen, phosph ...
Reprogramming nuclei
... (Koshland and Strunnikov, 1996; Nan et al., 1996). The properties of the chromatin that is assembled are strongly influenced by methylation of CpG dinucleotides, the major covalent modification of DNA found in vertebrate embryos (Antequera et al., 1989; Keshet et al., 1986). DNA methylation states a ...
... (Koshland and Strunnikov, 1996; Nan et al., 1996). The properties of the chromatin that is assembled are strongly influenced by methylation of CpG dinucleotides, the major covalent modification of DNA found in vertebrate embryos (Antequera et al., 1989; Keshet et al., 1986). DNA methylation states a ...
Microautophagy and macropexophagy may occur
... nitrogen-limiting conditions showed the expected morphology of organelle degradation (data not shown; [5]). Detailed experiments on cells subjected to both nitrogen limitation and glucose excess conditions, also including analysis of serial sections, demonstrated the characteristic morphological eve ...
... nitrogen-limiting conditions showed the expected morphology of organelle degradation (data not shown; [5]). Detailed experiments on cells subjected to both nitrogen limitation and glucose excess conditions, also including analysis of serial sections, demonstrated the characteristic morphological eve ...
Bovine Serum Albumin, pH 7.0
... pyrogens and toxic metals from the cells. It acts as a major antioxidant in cell culture media. It forms complexes with molecules that cause oxidative damage in non-bound state. These include bilirubin, free radicals, cysteine, glutathione, fatty acids, pyridoxal phosphate etc. Albumin also function ...
... pyrogens and toxic metals from the cells. It acts as a major antioxidant in cell culture media. It forms complexes with molecules that cause oxidative damage in non-bound state. These include bilirubin, free radicals, cysteine, glutathione, fatty acids, pyridoxal phosphate etc. Albumin also function ...
Cell and Molecular Biology - 外文文献下载
... The cell is the basic unit of life in all forms of living organisms, from the smallest bacterium to the most complex animal. On the basis of microscopic and biochemical differences, living cells are divided into two major classes: prokaryotes, which include bacteria, blue–green algae, and rickettsia ...
... The cell is the basic unit of life in all forms of living organisms, from the smallest bacterium to the most complex animal. On the basis of microscopic and biochemical differences, living cells are divided into two major classes: prokaryotes, which include bacteria, blue–green algae, and rickettsia ...
A theoretical analysis of the ephaptic feedback mechanism
... potential of -34.1 mV to the maximal light induced potential of -71.4 mV yields a shift of the Ca2+-current of -6.6 mV. As we will show, a shift of this magnitude can be obtained by substituting reasonable values for the two free parameters, p and T . Two free parameters, for which no precise value ...
... potential of -34.1 mV to the maximal light induced potential of -71.4 mV yields a shift of the Ca2+-current of -6.6 mV. As we will show, a shift of this magnitude can be obtained by substituting reasonable values for the two free parameters, p and T . Two free parameters, for which no precise value ...
Cdk1 regulates centrosome separation by restraining proteolysis of
... the duplicated SPBs. Spindle assembly is a cell cycle-regulated, multistep process. Yeast cells inherit one SPB, bearing a half-bridge, from their mothers. During G1 (prior to START), the tip of the cytoplasmic side of half-bridge acquires the SPB precursor known as ‘satellite’ (Byers and Goetsch, 1 ...
... the duplicated SPBs. Spindle assembly is a cell cycle-regulated, multistep process. Yeast cells inherit one SPB, bearing a half-bridge, from their mothers. During G1 (prior to START), the tip of the cytoplasmic side of half-bridge acquires the SPB precursor known as ‘satellite’ (Byers and Goetsch, 1 ...
Author`s personal copy
... their 8th cell cycle except for 5 pairs endoderm precursors (A7.1, A7.2, B7.1, B7.2, A7.5) and the pair of germ cell precursors (B7.6) (Fig. 1C3). The 5 pairs of endoderm precursors will then enter mitosis after undergoing apical constriction and basolateral shortening during an interphase of 80 m ...
... their 8th cell cycle except for 5 pairs endoderm precursors (A7.1, A7.2, B7.1, B7.2, A7.5) and the pair of germ cell precursors (B7.6) (Fig. 1C3). The 5 pairs of endoderm precursors will then enter mitosis after undergoing apical constriction and basolateral shortening during an interphase of 80 m ...
Light-powering Escherichia coli with proteorhodopsin
... energy into chemical energy, principally via chlorophyll-based photosynthesis (1, 2). Other light-harvesting mechanisms include the light-driven proton pump bacteriorhodopsin, used by halobacteria living in salt ponds to supplement respiration (3). In 2000, a novel light-driven proton pump, proteorh ...
... energy into chemical energy, principally via chlorophyll-based photosynthesis (1, 2). Other light-harvesting mechanisms include the light-driven proton pump bacteriorhodopsin, used by halobacteria living in salt ponds to supplement respiration (3). In 2000, a novel light-driven proton pump, proteorh ...
Sexual Reproduction in Higher Plants I: Fertilization and Zygotic
... occurs 40-120 seconds before the transient increase of cytoplasmic Ca++ concentration (Antoine et al. 2000, 2001a; 2001b). Studies using a cell surface Ca++ channel blocker, Cd+++, have found that the inhibition of the Ca+++ influx does not affect the Ca++ spike and the fusion of the sperm with the ...
... occurs 40-120 seconds before the transient increase of cytoplasmic Ca++ concentration (Antoine et al. 2000, 2001a; 2001b). Studies using a cell surface Ca++ channel blocker, Cd+++, have found that the inhibition of the Ca+++ influx does not affect the Ca++ spike and the fusion of the sperm with the ...
The in vitro development of blastocyst
... melanocytes and embryoid bodies (not shown). If, however, the aggregates were maintained in suspension, they developed only into embryoid bodies. After 5 days of culture about 60 % of the embryoid bodies had developed into structures with an outer layer of endoderm bordered by a basal lamina within ...
... melanocytes and embryoid bodies (not shown). If, however, the aggregates were maintained in suspension, they developed only into embryoid bodies. After 5 days of culture about 60 % of the embryoid bodies had developed into structures with an outer layer of endoderm bordered by a basal lamina within ...
Cell Cycle Control in Arabidopsis
... meristems, and the potency of non-dividing cells to re-enter the cell cycle. The study of plant cell cycle control genes is expected to contribute to the understanding of these unique developmental phenomena. The principal regulators of the eukaryotic cell cycle, the cyclin-dependent kinases (CDKs) ...
... meristems, and the potency of non-dividing cells to re-enter the cell cycle. The study of plant cell cycle control genes is expected to contribute to the understanding of these unique developmental phenomena. The principal regulators of the eukaryotic cell cycle, the cyclin-dependent kinases (CDKs) ...
video slide - Kealakehe High School
... • The egg lacks a centrosome. The basal body of the sperm’s flagella now acts as the centrosome and wraps itself around the centriole. • This will allows mitotic spindles to form for the first cell division. ...
... • The egg lacks a centrosome. The basal body of the sperm’s flagella now acts as the centrosome and wraps itself around the centriole. • This will allows mitotic spindles to form for the first cell division. ...
Diagnosis and Management of Limbal Stem Cell Deficiency
... by a stem cell supply located in the basal epithelial layer of the limbus. The importance of these stem cells is most apparent when their numbers are decreased. With a reduced ability to repopulate the corneal epithelium and an unstable ocular surface, patients with limbal stem cell deficiency (LSCD ...
... by a stem cell supply located in the basal epithelial layer of the limbus. The importance of these stem cells is most apparent when their numbers are decreased. With a reduced ability to repopulate the corneal epithelium and an unstable ocular surface, patients with limbal stem cell deficiency (LSCD ...
Regulation of germ line stem cell homeostasis
... therefore critical to maintain adequate cell numbers in health and diseases. Accumulating evidence suggests that stem cells behavior is regulated by both extracellular signals from their microenvironment, or niche, and intrinsic signals within the cells. Using diverse model organisms, much work has ...
... therefore critical to maintain adequate cell numbers in health and diseases. Accumulating evidence suggests that stem cells behavior is regulated by both extracellular signals from their microenvironment, or niche, and intrinsic signals within the cells. Using diverse model organisms, much work has ...
Anillin, a Contractile Ring Protein That Cycles from the Nucleus to
... In the early Drosophila embryo, maternally expressed genes have been identified that effect metaphase furrow formation (Postner et al., 1992; Sullivan et al., 1993). Similarly, three zygotic genes have been identified that specifically effect cellularization. These genes encode three novel proteins ...
... In the early Drosophila embryo, maternally expressed genes have been identified that effect metaphase furrow formation (Postner et al., 1992; Sullivan et al., 1993). Similarly, three zygotic genes have been identified that specifically effect cellularization. These genes encode three novel proteins ...
Non-neoplastic globe pathology non-neoplastic globe
... Diffuse chronic inflammation in diffuse form, Or : granulomatous inflammation with collagen degeneration (necrobiosis) in nodular form. ...
... Diffuse chronic inflammation in diffuse form, Or : granulomatous inflammation with collagen degeneration (necrobiosis) in nodular form. ...
Full text in pdf format
... cells, apparently lysed and showing some light cytoplasmic areas at the periphery of the host cells (Fig. 2). In some serial ultrathin sections it was possible to count thousands of RSS per cell, and hundreds on the same section, presenting well arranged layers (Figs. 2 & 3). The RSS show homogeneou ...
... cells, apparently lysed and showing some light cytoplasmic areas at the periphery of the host cells (Fig. 2). In some serial ultrathin sections it was possible to count thousands of RSS per cell, and hundreds on the same section, presenting well arranged layers (Figs. 2 & 3). The RSS show homogeneou ...
pensum for kjb 491-1997
... Intracellular Compartments and Protein Sorting (Chapter 12), p 695-697 (to Evolutionary..) (2.5 pages) 699 (proteins can move)-702 (most org) (3 pages) 704 (The transport of molecules)-710 (during mitosis) (6.5 pages) 723 (The endoplasmic reticulum)-746 (problems) (23 pages) Intracellular Vesicular ...
... Intracellular Compartments and Protein Sorting (Chapter 12), p 695-697 (to Evolutionary..) (2.5 pages) 699 (proteins can move)-702 (most org) (3 pages) 704 (The transport of molecules)-710 (during mitosis) (6.5 pages) 723 (The endoplasmic reticulum)-746 (problems) (23 pages) Intracellular Vesicular ...
Centromere dynamics
... single microtubule can generate [45,46]. A recent study indicates that at constant force and long measurement time, 2–3pN can favor nucleosome release [47]. This nucleosome release model predicts the existence of a protein complex between separated centromeres that limits the amount of DNA under te ...
... single microtubule can generate [45,46]. A recent study indicates that at constant force and long measurement time, 2–3pN can favor nucleosome release [47]. This nucleosome release model predicts the existence of a protein complex between separated centromeres that limits the amount of DNA under te ...
Pancreatic Beta Cell Lines and their Applications in Diabetes
... to escape from the negative control of the cell cycle and to reexpress telomerase (Freshney, 2000). The primary cause of senescence appears to be telomeric shortening, telomeres being the distal end of chromosomes composed of tandem repeats of the specific sequence. The function of telomeres include ...
... to escape from the negative control of the cell cycle and to reexpress telomerase (Freshney, 2000). The primary cause of senescence appears to be telomeric shortening, telomeres being the distal end of chromosomes composed of tandem repeats of the specific sequence. The function of telomeres include ...
File - wHOOSe Learning
... The skills in standard 5.1 are intended to define the “investigate” component and the understanding of the nature of science for all of the other fifth-grade standards. The intent of standard 5.1 is for students to continue to develop a range of inquiry skills, achieve proficiency with those ...
... The skills in standard 5.1 are intended to define the “investigate” component and the understanding of the nature of science for all of the other fifth-grade standards. The intent of standard 5.1 is for students to continue to develop a range of inquiry skills, achieve proficiency with those ...
Rotate into shape: MreB and bacterial
... that mediate teichoic acid synthesis in Gram-positive bacteria. Furthermore, MreB filaments dynamically rotate around the cell circumference in a manner dependent on the cell-wall assembly machinery. Thus, MreB may function to spatially organize the enzymatic activities required for proper bacterial ...
... that mediate teichoic acid synthesis in Gram-positive bacteria. Furthermore, MreB filaments dynamically rotate around the cell circumference in a manner dependent on the cell-wall assembly machinery. Thus, MreB may function to spatially organize the enzymatic activities required for proper bacterial ...
BIO201 Crimando Vocab 5 BIO201 Muscular System Vocabulary
... Study of muscles: ____________________ Fibrous band connecting muscle to bone: ____________________ Broad flat band connecting muscle to bone: ____________________ Fibrous sheath surrounding entire muscle: ____________________ Bundle of muscle cells: ____________________ Connective tissue sheath aro ...
... Study of muscles: ____________________ Fibrous band connecting muscle to bone: ____________________ Broad flat band connecting muscle to bone: ____________________ Fibrous sheath surrounding entire muscle: ____________________ Bundle of muscle cells: ____________________ Connective tissue sheath aro ...
Mitosis
Mitosis is a part of the cell cycle in which chromosomes in a cell nucleus are separated into two identical sets of chromosomes, each in its own nucleus. In general, mitosis (division of the nucleus) is often followed by cytokinesis, which divides the cytoplasm, organelles and cell membrane into two new cells containing roughly equal shares of these cellular components. Mitosis and cytokinesis together define the mitotic (M) phase of an animal cell cycle—the division of the mother cell into two daughter cells, genetically identical to each other and to their parent cell.The process of mitosis is divided into stages corresponding to the completion of one set of activities and the start of the next. These stages are prophase, prometaphase, metaphase, anaphase, and telophase. During mitosis, the chromosomes, which have already duplicated, condense and attach to fibers that pull one copy of each chromosome to opposite sides of the cell. The result is two genetically identical daughter nuclei. The cell may then divide by cytokinesis to produce two daughter cells. Producing three or more daughter cells instead of normal two is a mitotic error called tripolar mitosis or multipolar mitosis (direct cell triplication / multiplication). Other errors during mitosis can induce apoptosis (programmed cell death) or cause mutations. Certain types of cancer can arise from such mutations.Mitosis occurs only in eukaryotic cells and the process varies in different organisms. For example, animals undergo an ""open"" mitosis, where the nuclear envelope breaks down before the chromosomes separate, while fungi undergo a ""closed"" mitosis, where chromosomes divide within an intact cell nucleus. Furthermore, most animal cells undergo a shape change, known as mitotic cell rounding, to adopt a near spherical morphology at the start of mitosis. Prokaryotic cells, which lack a nucleus, divide by a different process called binary fission.