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Biological Bases of Behavior
Biological Bases of Behavior

... • Permits us to see human behavior as having a lot in common with that of other animals. • Considering our biology enables us to see how evolutionary processes have shaped our behavior. • When the biology/brain is disrupted, so is behavior! ...
genes - Vietsciences
genes - Vietsciences

... anemia and cystic fibrosis, are known to be genetic and are passed on in families. ...
DCMNext - Ambry Genetics
DCMNext - Ambry Genetics

... in childhood, so medical therapy can be considered in children and adults with DCM, or a family history of DCM. Heart transplantation may be necessary for patients that progress to end-stage heart failure. Those with DCM and complex conditions like Duchenne muscular dystrophy and Danon disease requ ...
Review of Oral Medications for Optometrists with the assistance of
Review of Oral Medications for Optometrists with the assistance of

... information regarding the identification of adverse/allergic reaction, dialysis, pregnancy and maximum daily doses will be discussed, which are prerequisites before prescribing oral pharmaceutical agents. Course Objectives  To review adverse/allergic reactions to oral medications  To review the FD ...
Medications to treat inflammatory arthritis
Medications to treat inflammatory arthritis

... •  If you are concerned about any side effects you are experiencing, contact your doctor to discuss them. *Note: common is 20-50% of patients and rare is less than 1% of patients ...
Home Infusion Of Anti-Infective Therapy
Home Infusion Of Anti-Infective Therapy

... on the body, as well as the body’s effects of absorption, distribution, metabolization, and excretion of the drug, and thus enables antiinfective selection and dosing of the most appropriate and effective drug, dosage, and administration regimen from the outset of therapy. PD/PK essentially describe ...
UL FFA Research
UL FFA Research

... biological systems and aims at identifying the underlying molecular events that lead from initial exposure to the chemical to the ultimate manifestation of toxic injury in an organism. The aim of our group is to understand how xenobiotics enter an organism or a cell, how are they metabolized, intera ...
Dr deOliveira - Will Drug Resistance Jeopardize the
Dr deOliveira - Will Drug Resistance Jeopardize the

Probability and Heredity
Probability and Heredity

... likely it is that an even will occur. • The laws of probability predict what is likely to occur, not necessarily what will occur. • If I flip a coin there is a 50% chance it will land on heads or tails. ...
Ligsay - Topic: Drug Discovery - Philippine Institute of Traditional
Ligsay - Topic: Drug Discovery - Philippine Institute of Traditional

... •  The  drug  discovery  and  screening  process  is   well   established   in   both   NCR   and   the   provinces.   However,   there   is   much   room   for   improvement.   It   is   the   general   consensus   among  scienCsts  and  r ...
2013 Drug Trends Presented by
2013 Drug Trends Presented by

... tissue and swallowed -- molly ushers in euphoria. It floods users' brains with neurotransmitters serotonin, norepinephrine and dopamine, making them feel elated, empathic and full of energy. Molly is a street name that has been in use for about a decade, Messer said. Although it originally referred ...
Drug List - Grand Saline ISD
Drug List - Grand Saline ISD

... • Primary: ...
two new third-generation antiepileptic drugs
two new third-generation antiepileptic drugs

... only affects the brain itself but also influences the social, vocational and psychological functioning. Despite much progress in understanding the pathophysiological processes underlying seizures, there are still about 30% of epilepsy patients that are not seizure free. There are many possible cause ...
27 October 2014 Dear Colleagues Discontinuation of Piportil
27 October 2014 Dear Colleagues Discontinuation of Piportil

... Unfortunately there is no generic or other branded product of pipotiazine palmitate depot injection available in UK. All patients currently receiving pipotiazine palmitate depot injection will therefore need to be reviewed and switched to an alternative treatment before March 2015. No new patients s ...
Notes 9.4 – DISRUPTING HWE EQUILIBRIUM
Notes 9.4 – DISRUPTING HWE EQUILIBRIUM

... 3. Genetic Drift Genetic Drift - The amount of an allele changes due to random events ...
shared care management of parkinson`s disease
shared care management of parkinson`s disease

... be preferred in most cases. *** -There is currently no proof that Rasagiline is superior to Selegiline, but there are theoretical reasons to suggest that Rasagiline may cause less side-effects. Patients should therefore only be started on Rasagiline, if they were previously unable to tolerate Selegi ...
(Piportil Depot) Oct 2014
(Piportil Depot) Oct 2014

... Unfortunately there is no generic or other branded product of pipotiazine palmitate depot injection available in UK. All patients currently receiving pipotiazine palmitate depot injection will therefore need to be reviewed and switched to an alternative treatment before March 2015. No new patients s ...
naltrexone (oral) - DavisPlus
naltrexone (oral) - DavisPlus

... syringe. Activate safety sheath by pressing against hard surface to cover needle. Store in refrigerator, do not freeze; may be kept at room temperature for 7 days. Administer IM into the gluteal muscle using pre-packaged 1 1/2- or 2– inch needle specifically designed for this drug. Avoid IV subcut o ...
trait
trait

... – Copies carried by an single individual called genotype ...
The pharmacokinetic profile of fesoterodine
The pharmacokinetic profile of fesoterodine

... Background: Fesoterodine is a new antimuscarinic agent developed for the treatment of overactive bladder. Fesoterodine itself is inactive and is rapidly and extensively converted by ubiquitous esterases to its principal active moiety, 5-hydroxymethyl tolterodine (5-HMT). 5-HMT is formed via biotrans ...
Antibiotics prescribing pattern in pediatric unit of Ayder referral
Antibiotics prescribing pattern in pediatric unit of Ayder referral

... Introduction: Antibiotics are among the most commonly prescribed drugs in pediatrics. Because of the emergence of antibiotic resistance, overall increase in health care cost and lack of uniformity in drug prescribing, monitoring as well as control of antibiotic use is important. Methodology: A retro ...
Review: New oral anticoagulants reduced stroke and systemic
Review: New oral anticoagulants reduced stroke and systemic

... renal dysfunction. Apixaban is safe for patients with moderate renal disease. Patients with creatinine clearance <30 mL/min should use warfarin. Once-daily rivaroxaban is more convenient than twice-daily dabigatran or apixaban. Patients on warfarin with good control of international normalized ratio ...
“The Supporting Players….”
“The Supporting Players….”

... Pneumocystis Carinii Pneumonia now known as Pneumocystis Jiroveci Pneumonia Can be very toxic ...
Molecular Mapping - Plant Root Genomics Consortium Project
Molecular Mapping - Plant Root Genomics Consortium Project

... Gene: a particular sequence of nucleotides along a molecule of DNA which represents a functional unit of inheritance. (Johannsen, 1909) Locus: the position of a gene on a chromosome or a genetic map. (Morgan, Sturtevant, Muller, and Bridges, 1915) ...
Patient Criteria for Starting Treatment
Patient Criteria for Starting Treatment

... Funding Request for Group Prior Approval for RITUXIMAB for the Treatment of REFRACTORY VASCULITIS or SYSTEMIC LUPUS ERYTHEMATOSUS NHS Hertfordshire will not normally fund any treatment where the patient does not meet the agreed criteria as outlined in this Group Prior Approval. If the consultant wis ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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