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Our Mission - Angelo State University
Our Mission - Angelo State University

... • Calcium: 1200 mg/day • Vitamin D: 400-800 IU/day • Exercise ‒ Aerobic ‒ Resistance • Green tea: 150mg per day ‒ polyphenols ...
Diuretics, ACEIs, ARBs, and NSAIDs: A
Diuretics, ACEIs, ARBs, and NSAIDs: A

... triple therapy. The use of double therapy was not associated with an increased risk of kidney injury. Triple therapy was associated with a 31% increase in risk of injury. The greatest risk was noted within the first 30 days of concurrent therapy, when it was nearly twice as high in patients compared ...
PS401- Lec. 3
PS401- Lec. 3

... Phenotype: the observable properties of an organism, produced by the interaction between the organism’s genotype and the environment (Johannsen, 1909).  Genotype: the genetic constitution in respect to the alleles at one or a few genetic loci under observation. (Johannsen, 1909). ...
Presentation - College of American Pathologists
Presentation - College of American Pathologists

... inhibiting free speech and access to information. ...
Hereditary Cancer Genetic Testing
Hereditary Cancer Genetic Testing

... In May of 2008, the Genetic Information Nondiscrimination Act or GINA, was signed into law and will add to the already strong legal protections that are in place on both the federal and state levels. GINA is a new federal law that protects Americans from being treated unfairly because of differences ...
Prescription of drugs not appropriate for children in a Pediatric
Prescription of drugs not appropriate for children in a Pediatric

... 50% less than intended. In this case the prescription of Paracetamol was classified as being off-label for presentation. Dipyrone, a drug wisely unlicensed by the FDA, is often employed with ICU patients because of its availability for intravenous use, which favors its prescription for hospitalized ...
Current and Upcoming Approaches to Medically Supervised
Current and Upcoming Approaches to Medically Supervised

... If MZs > DZs → Additive Genetic Influence (A) If DZs = MZs → Common Environmental Influence (C) If MZs < 1 → Unique Environmental Influence (E) ...
Emergence of Medication Assisted Therapy (MAT)
Emergence of Medication Assisted Therapy (MAT)

... • Keep informed about what is going on and try to apply it • Though there is no “magic bullet”, these medications can help your patients ...
Endocrinology Drug List
Endocrinology Drug List

...  T3 half life is 6days, peak effect after 9 days, prohormone  T3 halflife of 2-5 days, peak effect 1-2 days  Almost 100% bound to plasma proteins, mainly thyroxine binding globulin (TBG)  give as single oral dose  radioactive half life = 8 days  must be isolated to avoid pregnant women and chi ...
chapter11powerpointl
chapter11powerpointl

... Polygenic Inheritance Occurs when a trait is governed by two or more genes having different alleles Each dominant allele has a quantitative effect on the phenotype; these effects are additive Result in continuous variation of phenotypes ...
AUA, Alliance of Specialty Medicine Comments on 2015 Policy and
AUA, Alliance of Specialty Medicine Comments on 2015 Policy and

... Medicare   suggests   that   state   licensure   is   no   longer   sufficient   on   its   own.   The   proposal   would   limit   a   physician’s  ability  to  prescribe  medications  that,  under  current  regulations,  they  are  lawfully ...
Hence small distributors must pay the ACTUAL price
Hence small distributors must pay the ACTUAL price

... From my viewpoint as an industry veteran… “I believe that it is rather disingenuous for Premier Purchasing Partners, the other large national GPO’s and their partner manufacturers, in general, to point their fingers at the small drug distributors, who must pay a significantly higher price for their ...
Heredity Study Guide Answers
Heredity Study Guide Answers

... Selective breeding: specific traits are selected in the parents in order to ensure they are passed to the offspring & the genes are not actually altered 20. List some positive uses for selective breeding. The traits can easily be predicted. You can produce offspring that can serve a specific purpose ...
Chapter 4 Heredity and Evolution
Chapter 4 Heredity and Evolution

... allele frequency from one generation to the next. Allele frequencies are indicators of the genetic makeup of an interbreeding group of individuals known as a population. Small changes + Time + Natural Selection= Evolution ...
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Resources15 Reading resources

... It calls for guidelines ahead of any research into gene therapy for normal behavioural traits, ...
Exam-Objectives
Exam-Objectives

... 23. 3 models of drug abuse and what treatment options follow from each. Include some variables that explain drug use in the behavioral model. 24. What are at least 2 ways of assaying the reinforcing value of a drug? 25. Siegel’s theory of morphine tolerance. Be able to diagram it to explain toleran ...
Successes & Challenges In Development Of Drugs For
Successes & Challenges In Development Of Drugs For

... had to prove that any new drug was safe before it could be marketed ...
Antifungals
Antifungals

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Section 33_Addiction Medications 1_61 slides
Section 33_Addiction Medications 1_61 slides

... • Post hoc analysis of a randomized, double-blind, placebo-controlled study. Patients had ≥2 heavy drinking episodes/week during the month prior to screening. Inclusion did not require detoxification, abstinence or intent to abstain from alcohol1 • VIVITROL is indicated for the treatment of alcohol ...
Heredity - TeacherWeb
Heredity - TeacherWeb

... – The interaction of many genes to shape a single phenotype. – Example: human height ...
Heredity Study Guide
Heredity Study Guide

... Selective breeding: specific traits are selected in the parents in order to ensure they are passed to the offspring & the genes are not actually altered 20. List some positive uses for selective breeding. The traits can easily be predicted. You can produce offspring that can serve a specific purpose ...
CSI Case Profile The victim in the following case is a 35
CSI Case Profile The victim in the following case is a 35

... late that he was “popping painkillers like candy”. Certain painkillers are even more dangerous in large quantities than others. One indication that this may be the cause of death was a partially full acetaminophen bottle found on the scene. Chemical analysis of one pill (1454.10 g) revealed 924.08 g ...
Health Quiz
Health Quiz

... thin with long, slender fingers), while others also experience lifethreatening complications involving the heart and blood vessels. ...
Understanding drug uptake and binding within targeted disease
Understanding drug uptake and binding within targeted disease

... capable of providing quantitative information on current ongoing lung tissue matrix destruction would be invaluable assets in monitoring progression of disease in the context of the CT scans measuring emphysema and the functional tests. Over recent time, it has been demonstrated that early detection ...
Clinical Decisions
Clinical Decisions

... Get an overview of all of a patients genetic lesions, connections to Path Reports, clinical trials, drugs, etc.. ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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