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RN/LPN MedSurg Test
RN/LPN MedSurg Test

... 12. A patient with right hemiplegia is awake and alert. The patient is given exercise to do during the day. One afternoon the patient seems very discouraged, so the nurse plans to motivate her by: a) Reassuring her that there is no need for her to feel discouraged b) Reinforcing the small gains she ...
Matthew_Sigurdson_Final
Matthew_Sigurdson_Final

... (probably starting from a lower value and increasing gradually), while with genetic testing it would be calculated as 24.74 mg/week. The genetic basis for modifying the warfarin dose is mainly based in VKORC1, an enzyme that promotes clotting by producing active vitamin K. Thus a SNP which reduces V ...
Doxacil
Doxacil

... principally by interference with protein synthesis and binds to the 30S ribosomal subunit, thereby preventing the attachment of aminoacyl transfer RNA to messenger RNA-ribosome complex. Doxacil® is a broad spectrum antibiotic with the broadest spectrum of any known antibacterial agents. It is active ...
“Drug Exception Request,” DC4-648 provides information regarding
“Drug Exception Request,” DC4-648 provides information regarding

... non-formulary items, if therapeutically appropriate. All completed drug exception request forms (DC4-648) whether approved or disapproved are to be sent to the central office director of pharmacy services. Copies of approved drug exception requests will to be filed in the inmate’s medical record. ...
Considerations for Target Selection in CNS Drug Discovery Programs
Considerations for Target Selection in CNS Drug Discovery Programs

... from an analysis of the overlap between druggable biological target space and oral drug-like chemical space. The convergence of these two concepts requires first that the target play a role in human disease and second that it has the potential to be modulated in a selective manner by a small molecul ...
International panel of pathology leaders develop principles for
International panel of pathology leaders develop principles for

... address these opportunities to achieve excellence in patient care. Dr. Eslie Dennis, Vice President of Scientific Affairs for Ventana and chair of the International Pathology Patient Safety Advisory Board, said, ”We’re encouraged by the progress made last week in Tucson, and are certain that pat ...
nhse_qa43_7_final - Specialist Pharmacy Service
nhse_qa43_7_final - Specialist Pharmacy Service

... Rifampicin and rifabutin are more potent enzyme inducers than AEDs and women using these drugs long term (over 2 months) require an alternative method of contraception, i.e. avoiding the COC altogether, even the higher-dose tricycling regimens as explained above. The injectable depot medroxyprogeste ...
Liquid Handcuffs”: the bio-politics of methadone
Liquid Handcuffs”: the bio-politics of methadone

... treatment services, and thereby effectively bringing a larger segment of the opiate using population under the surveillance of state and medical institutions, the policy shifts in 1996 clearly represent “a matter of taking control of life and the biological processes of man-asspecies and of ensuring ...
Genotype X Environment Interactions
Genotype X Environment Interactions

... Conservation genetics is concerned with the evolution of quantitative traits and how their ability to adapt is affected by reduced population size, fragmentation, and changes in the environment. Immediate evolutionary potential of a population is determined by the heritability which is defined as th ...
Inheritance of Traits
Inheritance of Traits

... Let’s say the “F” stands for freckles The father has a genotype Ff – What is his phenotype? The mother has a genotype ff – what is her phenotype? The possible combinations of the offspring are Ff or ff – what could their phenotypes be? ...
MORGAM (an international pooling of cardiovascular cohorts)
MORGAM (an international pooling of cardiovascular cohorts)

... The main objective of the risk-factor component of the study is to assess the similarity of risk coefficients for the classic CVD risk factors in different parts of Europe, between men and women, and between age groups using large cohorts with standardized baseline measurements and carefully validat ...
Cardiovascular system pharmacology
Cardiovascular system pharmacology

... treatment of choice for rapid reversal. In severe overdose vit.K can be given by I.V injection but this taken 6-12 hrs to act. Agents used for treatment of anemia Anemia is defined as a below-normal plasma hemoglobin concentrations resulting from a decreased number of red blood cells or an abnormall ...
Bottlenecks and Founder Effects
Bottlenecks and Founder Effects

... Target III: Describe the two main causes of microevolution: genetic drift (bottleneck effect & founder effect) and natural selection. Text Reference: 23.3 Pre-lab Questions: Read the procedures before you answer the pre-lab questions. This may be checked, collected, or possibly be used on a pre lab ...
Modified-release preparations
Modified-release preparations

... maximum absorption from these preparations, it is essential that the drug is well absorbed throughout the entire GI tract. Drugs which are absorbed only at specific sites, such as iron16, folic acid and vitamin B12, are not suitable as m/r preparations.13 Drugs with a narrow therapeutic index, those ...
The Characteristics and Application of New Antipsychotic Drugs
The Characteristics and Application of New Antipsychotic Drugs

... Abstract: The characteristics of new antipsychotic drugs (atypical antipsychotic drugs) and their effective use are discussed. Atypical antipsychotic drugs can be considered modified drugs that resulted when the dopamine D2 receptor-blocking effect of typical antipsychotic drugs was either lowered i ...
Ken`s PowerPoint Slides
Ken`s PowerPoint Slides

... diuretic, calcium channel blocker, ACE inhibitor or ARB (Moderate) • Difference: JNC 7 recommended thiazides as first line treatment; beta blockers removed from first group of medications ...
Memory Medications
Memory Medications

... Antipsychotics: formerly used for agitation, but now a black box warning of an increased risk of death due to heart attack, pneumonia or other infection from use ...
Drugs of Addiction - City Vision University
Drugs of Addiction - City Vision University

... neurotransmitters and receptor sites are called agonists Drugs that block activity are called antagonists ...
Code: Resolution 1-1 Committee: Commission on Narcotic Drugs
Code: Resolution 1-1 Committee: Commission on Narcotic Drugs

Inferring Function From Known Genes
Inferring Function From Known Genes

... There are several ways in which known genes can be used to infer the function of unknown genes in a microarray experiment. 3) Pathway analysis If the genes are sufficiently well understood, they may be assembled into networks showing which genes regulate other genes. Unknown genes that have expressi ...
Inferring Function From Known Genes
Inferring Function From Known Genes

... There are several ways in which known genes can be used to infer the function of unknown genes in a microarray experiment. 3) Pathway analysis If the genes are sufficiently well understood, they may be assembled into networks showing which genes regulate other genes. Unknown genes that have expressi ...
Page 1 of 6 Bezalip 200mg Tablets - (eMC) print friendly 17/06/2016
Page 1 of 6 Bezalip 200mg Tablets - (eMC) print friendly 17/06/2016

... - Secondary causes of dyslipidaemia, such as uncontrolled type 2 diabetes mellitus, hypothyroidism, nephritic syndrome, dysproteinemia, obstructive liver disease, pharmacological treatment, alcoholism should be adequately treated before Bezafibrate therapy is initiated. - Bezafibrate and other fibra ...
Pharmacokinetics
Pharmacokinetics

... of its water to lipid solubility. Within the body, drugs may exist as a mixture of two interchangeable forms, either water (ionized-charged) or lipid (nonionized) soluble. The concentration of two forms depends on characteristics of the drug molecule (pKa, pH at which 50% of the drug is ionized) and ...
Questions
Questions

... genetically modified plants present unique animal and food safety concerns.” “I would urge you to eliminate statements that suggest that the lack of information can be used as evidence for no regulatory concern.” Gerald Guest, Director, FDA’s Center for Veterinary Medicine (CVM) ...
PowerPoint-Präsentation
PowerPoint-Präsentation

... Barley (Hordeum vulgare L.) was one of the first domesticated cereal grains, originating in the Fertile Crescent over 10,000 years ago. Barley ranks fifth in worldwide crop production and is widely cultivated in all temperate regions from the Arctic Circle to the tropics. In addition to its geograph ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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