• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Genetics…
Genetics…

... • Not just a pair of alleles (Rr), but at least two (RrTt) that work together on one trait. • These alleles or gene pairs don’t result in an either/or phenotype, but a range of phenotypes…the smallest to the biggest. • Phenotypes of many different forms • Examples: human height, skin color, etc ...
Prevention of prescription opioid abuse
Prevention of prescription opioid abuse

... among adolescents. This meeting highlighted the need for improved understanding of opioid prescribing practices in dental settings, including the amount that dentists typically prescribe, the amount that patients actually need for adequate pain relief and what patients do with unused medication. The ...
Popular Links - UNC School of Medicine
Popular Links - UNC School of Medicine

... SSRI Withdrawal Syndromes • More likely to occur with short t½ life agents (paroxetine warning) • May be due to sudden decrease in available synaptic 5-HT in face of down-regulated receptors • Onset 24-72 hours and lasts up to 7-14 days • Symptoms: dizziness, nausea, lethargy, headache, parasthesia ...
Medications Module: Instructor`s PowerPoint Slides with Notes
Medications Module: Instructor`s PowerPoint Slides with Notes

... At the end of this module you will be able to: 1. Describe common factors that are associated with ADEs 2. Describe best drug prescribing practices for nursing homes and other long term care settings 3. Describe the core and supportive roles of health care professionals and caregivers in medication ...
METHYLPHENIDATE for ADHD
METHYLPHENIDATE for ADHD

... vi. To initiate methylphenidate and change the dose (if required). vii. To prescribe the first 28 days supply of methylphenidate. viii. Following initiation, to send the GP a Shared Care Agreement Form (Page 7) inviting them to participate in shared care management of the patient. ix. To monitor the ...
Toxic epidermal necrolysis: an update
Toxic epidermal necrolysis: an update

... and actual mortality rates, and to evaluate the efficacy of treatment modalities[17]. SJS/TEN may be initiated by certain types of medication coupled with possible infection; however, few susceptibility genes have been identified as indicators for risk prediction, except for certain human leukocyte ...
Populations
Populations

... each individual is assumed to originate in one (only one) of K populations ...
Smiles, Bath Salts, Spice, Molly, Foxey, Krokodil, Kratom, Dragonfly
Smiles, Bath Salts, Spice, Molly, Foxey, Krokodil, Kratom, Dragonfly

... prison inmate who was described as being "red-eyed," "loony," "combative," and "intoxicated, lecturing everyone about life." Other inmates and staff reported seeing this prisoner drinking from a gallon container of Purell hand sanitizer over the course of the evening. It was discovered that this san ...
Gene Mapping Linked traits can be unlinked if crossing over occurs
Gene Mapping Linked traits can be unlinked if crossing over occurs

... individuals both heterozygous for the trait Dihybrid crosses involve two individuals both heterozygous for each of two traits A punnet square is a useful way to determine the genotypes and phenotypes from one and two trait crosses A test cross is a method for determining the genotype of an individua ...
about xarelto clinical studies
about xarelto clinical studies

... elective (planned) hip or knee replacement surgery. RECORD comprised four pivotal Phase III clinical trials that compared ‘Xarelto’ taken as one tablet, once-daily, with subcutaneous enoxaparin. RECORD1 and 2: total hip replacement surgery1,2 • RECORD1: Both treatments continued for 35+/-4 days • RE ...
Peter Mac Connectors - Peter Mac Education Portal
Peter Mac Connectors - Peter Mac Education Portal

... - A multi-centre Victorian Hospital Study found that for 17,000 doses in 300 patients up to 14% of intended doses where omitted - Time critical medications are those medications at greater risk of causing harm if not administered within a timely manner - Omitted doses of time critical medications ma ...
Opioid Abuse in Older Adults - Colorado Medical Directors Association
Opioid Abuse in Older Adults - Colorado Medical Directors Association

... – Naive initiation was more frequent among those with advanced age, those with cognitive impairment, and those with chewing difficulties – Opioid-naive residents were also more likely to be initiated on fentanyl relative to other LAOs (60.3% vs. 46.4%) and to use higher initial dosages • Given the s ...
Alzheimer disease - GEC-KO
Alzheimer disease - GEC-KO

... Who will be offered genetic testing and what do the test results mean? • Clinical testing is currently not available for lateonset AD (LOAD) or sporadic cases • When there are multiple related affected individuals, research testing may be available • APOE 4 testing is not recommended for risk asse ...
Restoril™ (temazepam) Capsules USP Rx only DESCRIPTION
Restoril™ (temazepam) Capsules USP Rx only DESCRIPTION

... Sleep disturbance may be the presenting manifestation of an underlying physical and/or psychiatric disorder. Consequently, a decision to initiate symptomatic treatment of insomnia should only be made after the patient has been carefully evaluated. The failure of insomnia to remit after 7 to 10 days ...
Chapter 5 I. Multiple Alleles
Chapter 5 I. Multiple Alleles

... Summary points 1. Dominance is a function of interaction between alleles. 2. Epistatsis is a function of interaction between genes. ...
Presentation 4
Presentation 4

... 1. The evidence for the role of lifestyle changes 2. The indications, contraindications and side effects of various antihypertensive classes ...
PHT 415 student Handout 3031
PHT 415 student Handout 3031

... semilog paper. The slope is equal to –k/2.3. The value for k a can be obtained by using the method of residuals or a feathering technique as following: 1. Plot the drug concentration versus time on semilog paper with the concentration values on the logarithmic axis. 2. Obtain the slope of the termin ...
Important Safety Information Regarding PAXIL® in Pediatric Patients
Important Safety Information Regarding PAXIL® in Pediatric Patients

... Canada, is alerting patients, their parents or guardians, and healthcare professionals that until further information is available Paxil should not be given to pediatric patients (children and adolescents under 18 years of age), due to concerns of a possible increased risk of suicidal thinking, suic ...
It`s A Five Star Steak - Personal.psu.edu
It`s A Five Star Steak - Personal.psu.edu

... It’s A Six Star Steak ...
Vivitrol Workshop Posted - Los Angeles County Evaluation System
Vivitrol Workshop Posted - Los Angeles County Evaluation System

... • Lower prevalence of SUD, anxiety, mood disorders but an anxiety and mood disorder that persists for a longer duration (SAMHSA, 2012; Breslau et al., 2005.) • Less satisfied with SUD treatment services (Marsh et al, 2009; Niv et al, 2009) • Less likely to complete SUD treatment (Bluthenthal et al, ...
Drug News Issue 29
Drug News Issue 29

... Further to the safety issue as reported in Issue No. 23 and 25 of Drug News, CHMP issued a public announcement on 16 March 2012 that it had finalised a review of Protelos and Osseor (strontium ranelate). CHMP concluded that these products were effective for treatment of postmenopausal women with ost ...
Document
Document

... Allele under case study: The ‘Asian’ getting a B is = failing gene -AA : must have an A+ -Aa - will be okay with an ‘A’ -aa - what a shame even an ‘A-’ is just awlright! (tsk tsk tsk) Initial frequency of these genes in a populations is: p = 0.8 (A) q = 0.2 (a) What 5 ways can you influence this al ...
IDE_IND_KMFINAL_plusAEslide_090310
IDE_IND_KMFINAL_plusAEslide_090310

... Are Investigational New Drug (IND) applications required for clinical studies of botanical products that are also lawfully marketed as dietary supplements in the U.S.? ...


... drug level obtained by the Anser IFX assay would be used to direct further care for the member. The member's infliximab level came back at approximately 21 ng/ml. The consultant noted that the target value has been investigated and is likely between 3 to 7 ng/ml, but this remains speculative. The co ...
Hauptvorlesung Evolutionsbiologie
Hauptvorlesung Evolutionsbiologie

... The Hardy-Weinberg Law assumes that populations are large. Therefore, there is no variation resulting from the process of sampling gametes which will produce the next generation. Genotypic frequencies remain constant from generation to generation because gene frequencies are representative samples o ...
< 1 ... 761 762 763 764 765 766 767 768 769 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report