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Betasone - Pharmaline
Betasone - Pharmaline

... caused by herpes simplex, chikenpox, candida or bacteria (impetigo). It is also contraindicated in patients with known hypersensitivity to any of its components. PRECAUTIONS: Continuous long-term topical use may lead to atrophic changes especially in the face. Avoid contact with eyes. If irritation ...
University of Georgia Sports Medicine
University of Georgia Sports Medicine

... The patient may complain of side effects following the administration of epinephrine. Possible side effects include increased heart rate, pale skin (pallor), dizziness, chest pain, headache, nausea, vomiting, excitability and anxiousness. Reassessment Following the administration of epinephrine, it ...
Marketed Drugs for Prostate Cancer
Marketed Drugs for Prostate Cancer

... in serum testosterone and PSA levels. No data on progression free survival or overall survival Safety: few minor side effects. Injection site hematoma and irritation, and flushing Efficacy: Emcyte combination therapy with taxotere significantly reduces PSA levels, tumor size, and extends survival by ...
HOSPITAL NAME INSTITUTIONAL POLICY AND PROCEDURE
HOSPITAL NAME INSTITUTIONAL POLICY AND PROCEDURE

... B. If the drug comes into contact with your skin, flush immediately and wash thoroughly with soap (NOT HIBISTAT) and water. If an eye or mucous membranes come into contact with the drug, flush with copious amounts of water for approximately 15 minutes. 9. Place disposable contaminated materials in a ...
Intersect ENT Announces Enrollment of First Patient In Phase III
Intersect ENT Announces Enrollment of First Patient In Phase III

... initiation of RESOLVE II, a pivotal Phase III clinical study to support U.S. Food and Drug Administration (FDA) approval of the company’s RESOLVE steroid releasing implant designed to treat patients with recurrent sinus obstruction in the office setting. RESOLVE II is the final planned clinical tria ...
Takeda and Lundbeck Announce FDA Approval
Takeda and Lundbeck Announce FDA Approval

... short-term trials discontinued treatment due to an adverse reaction, the most common being nausea, compared with 4 percent of placebo-treated patients in these studies. Brintellix and other antidepressants may cause serious side effects. See Important Safety Information below. In clinical studies, B ...
Drug, substance that affects the function of living cells
Drug, substance that affects the function of living cells

... adults require two tablets of aspirin. A half tablet may provide no relief from pain while ten tablets may cause burning pain in the stomach or nausea. The doses prescribed by physicians are those recommended by each drug’s manufacturer to produce the best therapeutic, or medically beneficial, respo ...
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Synthesis and Characterizat /Cloisite30B (MMT) Nanoco

... Curcumin (diferuloylmethane), a polyphenol, is a low molecular- weight active principle of theperennial herb Curcuma longa (commonly known as turmeric). Recent evidence suggests thatcurcumin is a highly pleotropic molecule that interacts physically with its diverse range ofmolecular targets includin ...
A Peak at PK – An Introduction to Pharmacokinetics
A Peak at PK – An Introduction to Pharmacokinetics

Epi-Pen Policies and Procedures
Epi-Pen Policies and Procedures

... The patient may complain of side effects following the administration of epinephrine. Possible side effects include increased heart rate, pale skin (pallor), dizziness, chest pain, headache, nausea, vomiting, excitability and anxiousness. Reassessment Following the administration of epinephrine, it ...
Medication Types
Medication Types

... Morphine by mouth has a wide range of effects in different individuals because of its variable 20 - 50% bioavailability (the proportion of drug taken up from the bowel after oral administration). This means that by mouth there can be a 2.5 times difference in the dose required to achieve comfort bet ...
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Mechanism of Action

... PBMNC Following 5 days of G3139 ...
Types of Dominance
Types of Dominance

... • How could you figure out it’s genotype? – Assume that you do not have access to the technology to sequence the alleles ...
Acute Effects of Drug Abuse in Schizophrenic Patients: Clinical
Acute Effects of Drug Abuse in Schizophrenic Patients: Clinical

... the above sources of data on drug effects in schizophrenia must take into account certain specific limitations. Data from laboratory studies should be interpreted with caution because experimental paradigms to test drug effects may not duplicate the environment, or the type, dose, and purity of drug ...
Light therapy for cold sores
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... rates for pooled data were 4.3 +/- 1.8 days (mean +/- SD) with light treatment as compared with 8.5 +/- 3.0 days for aciclovir groups (P < 0.0001). However the majority of patients (71-93%) started treatment between 18-36 hours of onset of symptoms. NICE Clinical Knowledge Service recommends that ac ...
CHAPTER 11 NOTES – GENETICS
CHAPTER 11 NOTES – GENETICS

... 2. In the F2 generation the recessive allele once again showed up! a. Roughly 75% of the F2 generation were Tall pea plants b. Roughly 25% of the F2 generation were Short pea plants c. The only way that the recessive allele can once again be exhibited in F2 generation plants is for the alleles to se ...
Quantitative Genomics slides
Quantitative Genomics slides

... • Mitochondrial DNA: non-nuclear DNA, inherited only from the mother ...
Conventional Drugs
Conventional Drugs

... restore internal homeostasis, the number of receptors for particular endogenous ligands can be increased in number (up-regulated) or decreased in number (down-regulated). This feedback mechanism allows for better fine-tuning of the bodyʼs metabolic activities. It also explains why the activity of ce ...
Yale oral steroid patient handout (PM 9-20-10)-2
Yale oral steroid patient handout (PM 9-20-10)-2

... the underlying condition being treated and on your other health issues. Two general principles guide dosing: • Both medications are started at higher doses, with the dosage gradually tapered over days, weeks, or months. • To reduce the risk of side effects and complications, please take the medicati ...
Genetic pleiotropy in complex traits and diseases: implications for
Genetic pleiotropy in complex traits and diseases: implications for

... mixture based on cross-locus correlations (BUHMBOX), for distinguishing between these possibilities. In order to detect heterogeneity involving the misdiagnosis of disease B cases as disease A, the approach tests for an excess of positive correlations between independent disease B risk alleles in in ...
Genetesting_to_post
Genetesting_to_post

... • not possible in some cases due to difficulty in obtaining eggs or early embryos and problems with DNA analysis procedures • costly and usually not covered by insurance ...
biliary excretion
biliary excretion

Available through Online Review Article www.ijptonline.com
Available through Online Review Article www.ijptonline.com

... resulting into irritation and allergic reactions in significant users. Other drawbacks of topical formulations are uncontrolled evaporation of active ingredient, unpleasant odour.2 The fundamental appeal of the microsponge technology stems used instead of conventional formulations for releasing acti ...
Alcohol, Tobacco, and Drugs
Alcohol, Tobacco, and Drugs

... Define designer drugs. What are they also known as? 2. List 3 risks associated with designer drugs? What is Crystal Meth? What does it look like? What are 2 slang names for Crystal Meth? How is Crystal Meth abused (how is it taken into the body)? What is MDMA? What does it look like? What are 2 slan ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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