• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Curanderismo - VAC-Valley AIDS Council
Curanderismo - VAC-Valley AIDS Council

... and make up of Latin America, in particular, Cuba, Haiti, Bra‐ zil, Trinidad and Puerto Rico.   While the basic religious beliefs remain the same, the relig‐ ion is now a fusion of authentic Yoruba from Africa; indige‐ nous native (Indian) beliefs and Christianity from Europe.   Basic Yoruba belief  ...
July 2012 - Kaiser Permanente
July 2012 - Kaiser Permanente

...  GlaxoSmithKline announced changes to ondansetron drug label to remove the 32mg single intravenous dose  Updated label states intravenous ondansetron can be used in adults and children with chemotherapy-induced nausea and vomiting at 0.15mg/kg up to a maximum of 16mg per dose, administered every 4 ...
Bruyere/Primrose Units - R. Halil, August 2015
Bruyere/Primrose Units - R. Halil, August 2015

...  Consider (in order): ...
Phenotype of Breast Cancer (PowerPoint) Northwest 2011
Phenotype of Breast Cancer (PowerPoint) Northwest 2011

... A. Yes B. No C. Sometimes? ...
Slide 1
Slide 1

... distribution of tested SNPs was observed between revised and unrevised THA patients (p > 0.05, Figure 3). ...
EPIDEMIOLOGY OF GENETIC DISEASES AND ITS CONTROL
EPIDEMIOLOGY OF GENETIC DISEASES AND ITS CONTROL

... This approach requires identifying heterozygous individuals for any particular defect by screening procedures and explaining to them the risk of having affected children if they marry another heterozygote for the same gene. Retrospective genetic counseling Most genetic counseling at present are retr ...
Pharm 22, 23- Drugs for Affective Disorders Depression
Pharm 22, 23- Drugs for Affective Disorders Depression

...  Benzodiazepines bind to an allosteric site formed by the cleft between α and γ subunits  This facilitates GABA binding & increases the frequency of chloride channel opening  P’kinetics: well absorbed; distributed into the brain according to lipid solubility; extensively metabolized in the liver; ...
document
document

... is difficult to determine exactly where on such a scale the heterozygote is located. At the molecular level, incomplete dominance is generally caused by a quantitative effect of the number of "doses" of a wild-type allele; two doses produce most functional transcript and therefore most functional pr ...
Assessment of Intravenous Admixtures in Hospitalized
Assessment of Intravenous Admixtures in Hospitalized

... Intravenous Incompatibilities are the undesirable reactions that occur when two are more drugs are administered through a single intravenous line or given in a single solution. Because of this incompatibility, the patient could experience toxicity or an incomplete therapeutic effect. 2 There are thr ...
Phenotypic diversity associated with mitochondrial DNA m
Phenotypic diversity associated with mitochondrial DNA m

... allowed comparing mutation load and clinical phenotype. That analysis reinforced the steep threshold effect observed in single muscle fibers as 100% mutation (Patients 2 and 3) was associated with the most severe phenotype, compatible with Leigh syndrome, while 92% mutation (Patient 1) was observed ...
Corporate Manager, Clinical Knowledge Management and Decision
Corporate Manager, Clinical Knowledge Management and Decision

... Roche Holding AG is launching the first gene test able to predict how a person will react to a large range of commonly prescribed medicines, one of the biggest forays yet into tailoring drugs to a patient's genetic makeup. The test is part of an emerging approach to treatment that health experts exp ...
Drugs - Eye Enucleation
Drugs - Eye Enucleation

... Inadvertent intraarterial injection may cause adverse reactions. Do not use in cattle showing hypersensitivity to flunixin meglumine. The drug is contraindicated in animals with hepatic disease, renal and cardiovascular impairment, gastrointestinal ulceration and/or platelet disorders. It is also co ...
Quetiapine - Barnsley CCG
Quetiapine - Barnsley CCG

... It is optional for GPs to participate in taking on responsibility for shared care for the patient. GPs will take on shared care only if they are willing and able. ...
AGS Beers Criteria Summary for Patients and Caregivers.
AGS Beers Criteria Summary for Patients and Caregivers.

... prescribing for adults 65 or older. These medications pose a higher risk of side effects, may not work as well in an older person, and may be replaced with safer or more effective medications or non-drug remedies. • Medications used for 14 common health problems that are potentially inappropriate ...
Bipolar Disorder - Steven Bander
Bipolar Disorder - Steven Bander

... • You may have a patient without a history of severe and/or recent mania and is not taking any antimanic medication • The treatment step would be to provide the patient with lamotrigine ...
-click here for handouts (3 per page)
-click here for handouts (3 per page)

... need high doses –Counteract affinity of drug for receptor –Need large amt of antagonist for large amt of drug  Monitor for noncardiogenic pulmonary edema if person is “found down” and then becomes hypoxemic ...
2002 Memorandum OfC  17
2002 Memorandum OfC 17

... information to FDA at least 75 daysbefore a new dietary ingredient or a dietary supplement containing it is introduced or delivered for introduction into interstate commerce. This information must include the basis on which the manufacturer or distributor has concludedthat the new dietary ingredient ...
Assessing natural variation in genes affecting Drosophila lifespan
Assessing natural variation in genes affecting Drosophila lifespan

... insulin signaling, some mutations of which dramatically extend adult lifespan in fruit flies. The finding that InR may exhibit genetic variation for lifespan in natural populations is of particular interest to both the molecular and the evolutionary gerontologist. InR is homologous to the C. elegans ...
LINKAGE  DATA a, the
LINKAGE DATA a, the

... Several asci from the above ci-ass were tested for mating type and on the basis of these considerations Isloo appears to be located to the left of al-2 on chromosome I. ...
This listing of Pathology/Laboratory applications is being posted
This listing of Pathology/Laboratory applications is being posted

... Pathology/Laboratory CPT Code Change Applications February 2017 CPT® Editorial Panel Meeting Pathology/Laboratory CPT Code Change Applications that have been submitted for consideration by the CPT Editorial Panel at its February 2017 meeting are listed below. These applications will be included in t ...
Active International Research into Cardiometabolic and Liver Effects
Active International Research into Cardiometabolic and Liver Effects

... Furthermore, it appears that the citrus extract also inhibits the reabsorption of cholesterol in the intestines, a mechanism similar to ezetimibe, a drug that has recently shown additional benefits in heart attack risk. A recent Wall Street Journal article on the clinical effectiveness of extracts f ...
MGA 2e Chapter 17
MGA 2e Chapter 17

... eliminate the gene product, or change the ratio of it to all other gene products. All three outcomes upset a previously balanced system. While a new and “better” balance may be achieved, this is less likely than being deleterious. 14. Wild-type alleles are usually dominant because most mutations res ...
Learning Goal B
Learning Goal B

... • He allowed each variety to self-pollinate for several generations to ensure that they were true-breeding (offspring always exhibited the same trait). He called this the P1 (parent) Generation. • He took two of these parent plants with contrasting forms of the same trait and crosspollinated them. • ...
Review notes
Review notes

... 2) Cytochrome P450 (electron acceptor); CYP PPAR ligands, CYP1, CYP2E, CYP2B Polymorphisms cause changes in drug metab: CYP2C19, CYP2B, CYP2D6 Induction of P450 enzymes=metabolize drug Glucoronidation Sulfation Acetylation Amino acid Conj Glutathione Conj Fatty acid Conj Condensation Reaction ...
Molecular study of a consanguineous family with autosomal
Molecular study of a consanguineous family with autosomal

... severe cases were X-linked; however, a recent review suggests that X-linked mutations contribute to no more than 10% of the cases, [13] and thus it is expected that there will be many more autosomal genes whose mutations cause NS-ID, both dominant and recessive. However, as a result of the high degr ...
< 1 ... 686 687 688 689 690 691 692 693 694 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report