• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
DEAFNESS and GENETIC COUNSELLING
DEAFNESS and GENETIC COUNSELLING

... prelingual HL DFNX6- high-frequency loss from 5-7 yrs progressing to severe to profound HL by adulthood over all frequencies. ...
Antidepressants_E
Antidepressants_E

... Depression is one of the most common psychiatric disorders. At any given moment, about 3–5% of the population is depressed, and an estimated 10% of people may become depressed during their lives. The symptoms of depression are often subtle and unrecognized both by patients and by physicians. Patien ...
Group 1
Group 1

... administered was varied between subgroups of rats…  Group 1A were injected with heroin in the Colony room where they had received all their previous injections of heroin  Group 1B were injected with heroin in the Noisy room - where they had never received any previous injections of heroin  Group ...
Treatment of Depression in the Elderly Arash Mirabzadeh, MD
Treatment of Depression in the Elderly Arash Mirabzadeh, MD

... In elders who have co-existing chronic medical conditions, the presence of depressive symptoms increases role impairment, utilization of medical services and treatment costs decreases patients' compliance with their medical treatments and alters the course of disease that leads to higher mortality a ...
Laboratory #4: Segregation of Traits According to Mendel
Laboratory #4: Segregation of Traits According to Mendel

... plants, so after multiple generations (without interference) of self-fertilization they become homozygous for all their important qualitative genes and are known as a pure line. Mendel crossfertilized different homozygous pea lines to see what would happen. As a result of his work with peas, Mendel ...
Expansion of specialized metabolism
Expansion of specialized metabolism

... that these three superfamily genes are highly multiple in range from 50 to 400 genes and are significantly diversified in terms of protein sequences and biochemical functions among seed plants (Caputi et al. 2012; Kawai et al. 2014; Nelson and Werck-Reichhart 2011; YonekuraSakakibara and Hanada 2011 ...
Pathological Physiology
Pathological Physiology

... A 46-year-old patient suffering from the diffuse toxic goiter underwent resection of the thyroid gland. After the surgery the patient presents with appetite loss, dyspepsia, increased neuromuscular excitement. The body weight remained unchanged. Body temperature is normal. Which of the following has ...
Guidelines for Use of Meperidine
Guidelines for Use of Meperidine

Ch. 18-Drugs used to Lower Lipids
Ch. 18-Drugs used to Lower Lipids

Pharmacy Law Review 2010
Pharmacy Law Review 2010

... If an article is alleged to be misbranded because the labeling or advertising is misleading, then in determining whether the labeling or advertising is misleading there shall be taken into account (among other things) not only representations made or suggested by statement, word, design, device, or ...
3-23_Genetics
3-23_Genetics

... In apple trees, the allele for green apples (G) is dominant. The allele for red apples (g) is recessive. If an apple tree has the genotype GG, what would be the PHENOTYPE of the apples produced? ...
Hydroxypropyl Methyl Cellulose (HPMC)
Hydroxypropyl Methyl Cellulose (HPMC)

... According to 21 CFR 210.3(b)(8), an inactive ingredient is any component of a drug product other than the active ingredient. Only inactive ingredients in the final dosage forms of drug products are in this database. The Inactive Ingredients Database provides information on inactive ingredients prese ...
ABG505
ABG505

... phenotypic classes. i.e. They show variation from one phenotypic extreme to another. 3. Their study depends on measurement instead of counting. 4. The traits are usually affected by environment to a large extend. Phenotypes are the outcome of interaction among genes and between genes and the environ ...
Understanding Parkinson`s Medications
Understanding Parkinson`s Medications

... Class/Type and Medications ...
Genetic Linkage Analysis
Genetic Linkage Analysis

... • Probability of expressing a phenotype given genotype. Penetrance is either “complete” or “incomplete”. If Y is a phenotype and (A, a) is a disease locus, then penetrances are ...
Codeine use in children and ultra-rapid metabolisers
Codeine use in children and ultra-rapid metabolisers

... In August 2007, the FDA published a press release and public health advisory Use of Codeine By Some Breastfeeding Mothers May Lead To Life-Threatening Side Effects In Nursing Babies and the labelling of codeine-containing products was updated to describe this risk.12 ...
overview of inheritance - American Heart Association
overview of inheritance - American Heart Association

... Currently, the cause of cardiomyopathies in most children is poorly understood, but in a subset of children it is clear that the cause is an error or mistake in a gene. Genes are the blueprints or instructions that determine how the parts of our bodies will be formed and how they will function. Gene ...
EXPRESS SCRIPTS CANADA® DRUG TREND REPORT 2016
EXPRESS SCRIPTS CANADA® DRUG TREND REPORT 2016

... knowledge required to determine which drug is the most cost-effective, clinically appropriate option for their treatment. When a member suffers from multiple chronic conditions, these decisions become even more difficult as factors such as drug interactions and adverse event profiles must be conside ...
fgdfgdgsty - Latvijas universitāte
fgdfgdgsty - Latvijas universitāte

Codeine use in children and ultra-rapid metabolisers
Codeine use in children and ultra-rapid metabolisers

2. Thyroid gland
2. Thyroid gland

... • The short t½ of these drugs has little effect on their effect because they are selectively accumulated in the thyroid. • Propylthiouracil is preferable during pregnancy because it does not cross placental barrier (because it is strongly bound to plasma protein). ...
Factor V Leiden
Factor V Leiden

... molecular test can distinguish heterozygotes from homozygotes.3 The basis of the coagulation test is inhibition of activated factor V by APC; as a result the clotting time is prolonged. Activated protein C is added to the patient’s plasma and the activated partial thromboplastin time (aPTT) test is ...
locomotion in a consanguineous kindred the gene
locomotion in a consanguineous kindred the gene

... phenotypes for whom the underlying genetic cause is still unknown. The first cohort consisted of 750 patients with structural cortical malformations or degenerative neurological disorders. By using the whole-genome genotyping data based on Illumina Human 370 Duo or 610K Quad BeadChips, we did not id ...
(Narcan) for pre-hospital opiate overdose - teaching
(Narcan) for pre-hospital opiate overdose - teaching

...  Naloxone’s half-life can be shorter than that of the opiate, so as it breaks down the patient may become somnolent again. Intravenous (IV) naloxone and the blood brain barrier:  When naloxone is injected intravenously, we define it as being 100% bioavailable. No higher peak plasma levels are poss ...
Thyroid gland and antithyroid drugs
Thyroid gland and antithyroid drugs

< 1 ... 554 555 556 557 558 559 560 561 562 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report