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Syllabi of Master of Pharmaceutical Sciences in SEMESTER-I (M
Syllabi of Master of Pharmaceutical Sciences in SEMESTER-I (M

... dissolution. Dissolution test, Historical development & USP dissolution test. Dissolution model like Hixson-Crowell, Higuchi’s Model. Drug release modeling through polymer matrix & laminates. Concept of membrane controlled delivery & its importance in dosage form design. MICRO ENCAPSULATION: Theory, ...
Hypertensive Crisis during Pregnancy
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... • Admitted by High-Risk Obstetrical ...
Atorvastatin 80 mg daily - Centre for Medicines Optimisation
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... atorvastatin arm received an 80 mg daily dose, were reviewed but are not included in this summary. Adverse effects Adverse events experienced by patients treated with atorvastatin 80 mg daily included myalgia and myopathy, rhabdomyolyis, hepatic enzyme elevations, headache, back pain, depression and ...
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... SSc is not inherited in a Mendelian fashion, and although SSc pathogenesis is unclear, it is believed that both genetic and environmental factors contribute to disease susceptibility and clinical expression or progression [13]. Complex genetic diseases are influenced by the interplay of multiple gen ...
Pain Scenarios - mededcoventry.com
Pain Scenarios - mededcoventry.com

... Respiratory rate < 8 and sedation score = 3 or sedation score 3 regardless of respiratory rate • give naloxone 100 micrograms IV every 5 minutes • Call for anaesthetic help • Prevent vomiting with regular antiemetics ...
Genetics - Faperta UGM
Genetics - Faperta UGM

... by the combined interaction of many gene loci. These are called polygenic traits.  Several genes at different loci interact to control the same character  Produces continuous variation  Phenotypic distribution: Bell-shaped curve  Often modified by environmental effects ...
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... 56% stated that it had affected their lives (e.g. time off work, less active, depressed, sex life).4 A systematic review (2013) of recent key studies on the prevalence of chronic pain found3: o chronic pain has a weighted average prevalence in adults of 20%; 7% have neuropathic pain and 7% severe pa ...
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Finlepsin 200 tablets 200 mg 1
Finlepsin 200 tablets 200 mg 1

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Privacy in Pharmacogenetics: An End-to-End Case Study of
Privacy in Pharmacogenetics: An End-to-End Case Study of

... non-medical settings have shown that leaking datasets can enable de-anonymization of users and other privacy risks. In the pharmacogenetic setting, datasets themselves are often only disclosed to researchers, yet the models learned from them are made public (e.g., published in a paper). Our focus is ...
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the use and abuse of drugs a handbook for health educators

... medical prescription or expert advice as well as abusing those prescribed legitimately. A substance may not be dangerous of itself; but the improper use of nearly any substance can be dangerous. Unfortunately the search for drugs has, in the past, often been a search for "magic" and, except in scien ...
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The pharmacological management of Alzheimer`s disease

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Inhaler Sequence
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... reserved for rescue, as needed. With few exceptions, nearly all of those who tried my recommended pattern found the following to be true: (1) Their long-acting medications became far more effective than they had been when taking the short-acting forms first. (2) Patients who had felt no increased or ...
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Incentive Salience and the Transition to Addiction
Incentive Salience and the Transition to Addiction

... Most adults have used a potentially addictive drug at least once in their lifetime, if caffeine, alcohol, and nicotine are included in addition to illicit drugs. In some cases, contact with a substance is so frequent and socially accepted that many in society fail to recognize it as a “drug.” Howeve ...
© Jones and Bartlett Publishers, LLC. NOT FOR SALE OR
© Jones and Bartlett Publishers, LLC. NOT FOR SALE OR

... 5. Illicit or “recreational drugs” Because this text is directed at EMS professionals and other health care providers, the terms drugs, medicines, and medications will be used interchangeably, and readers should presume that all five types of drugs are included. New drugs are coming on the market al ...
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... Failing to register as a Controlled Substance Prescribing Practitioner if you are a physician, or an osteopathic doctor who prescribes any controlled substance for the treatment of “chronic nonmalignant pain”. Chronic Nonmalignant Pain is defined as pain that is unrelated to cancer or rheumatoid art ...
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genetics sheet#11,by Thulfeqar Alrubai`ey

... What is the meaning of genetic linkage? When there are two genes that are close to each other, they will not be separated by crossing over during meiosis. In other words, they will be segregated together because the chance of having crossing in the area between these two genes is very small. How can ...
CHEMICAL TRANSMITTERS IN THE CNS Drugs acting on CNS
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... b. Cancer pain: terminal cancer pain c. Colicy pain: biliary & renal (add atropine) d. Bone fractures (not in head injury) e. Post-operative pains (not after eye or gall bladder operations) 2) Pre-anaesthetic medication: to provide analgesia & sedation ...
Effect of acute and chronic tianeptine on the action of classical
Effect of acute and chronic tianeptine on the action of classical

... Background: The aim of the study was to analyze the influence of acute and chronic treatment with tianeptine, an antidepressant selectively accelerating presynaptic serotonin reuptake, on the protective activity of classical antiepileptic drugs in the maximal electroshock test in mice. Methods: Elec ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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