• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Non-Steroidal Anti-Inflammatory Drugs (NSAID
Non-Steroidal Anti-Inflammatory Drugs (NSAID

... inflammation and pain relief. Opioid analgesics have demonstrated high abuse potential and are often more problematic to dose than NSAIDs.24,25 Studies have also shown that opioid users are at a higher risk for bone fractures compared to those taking NSAIDs in older adult populations.24,25 The same ...
View slide set - Mayo Clinic Center for Tuberculosis
View slide set - Mayo Clinic Center for Tuberculosis

... ©2014 MFMER | slide-10 ...
Constraints for genetic association studies
Constraints for genetic association studies

... Email: [email protected] ...
Genetic Background o#63E86C
Genetic Background o#63E86C

... for gluten proteins present in dietary wheat, rye, and barley. It affects approximately 1:100-300 individuals,[1-3] although only 1 person in ~8 is aware of being affected because the symptoms may be mild or nonspecific.[4] Environmental, genetic, and immunologic factors are important in the pathoge ...
LETTER TO THE EDITOR Flaccid Paralysis Due to Chronic Baclofen
LETTER TO THE EDITOR Flaccid Paralysis Due to Chronic Baclofen

... probably alcohol-related. Evoked sensory cortical potentials did not show any abnormalities of the central pathways. Baclofen was reduced by 10 mg every 2 days. Six weeks ...
One Compartment Open Model IV bolus
One Compartment Open Model IV bolus

... An adult male patient was given the first dose of an antibiotic at 6:00 AM. At 12:00 noon the plasma level of the drug was measured and reported as 5 µg/ml. The drug is known to follow the one compartment model with a half-life of 6 hours. The recommended dosage regimen of this drug is 250 mg q.i.d. ...
MINUTES North Carolina Medical Board
MINUTES North Carolina Medical Board

... collect timeline data from other state medical boards to reference in setting goals, and (3) identify ways to measure the quality of our work such as survey responses and random quality assurance checks. Otherwise, accept the Task Tracker report as reported. Board Action: The Board accepted the Comm ...
Familial Polyposis Gene Testing - Providers
Familial Polyposis Gene Testing - Providers

... The prevalence data reported from national registries include all of the APC-associated polyposis conditions (except possibly some cases of attenuated FAP); reported prevalence is 2.29 to 3.2 per 100,000 individuals (Burn et al. 1991, Jarvinen 1992, Bülow et al. 1996). AFAP is likely underdiagnosed, ...
Commonwealth of Independent States Executive Committee Ul
Commonwealth of Independent States Executive Committee Ul

... -2Information on the activities of the Commonwealth of Independent States to combat drug trafficking The Commonwealth of Independent States (CIS) is actively involved in international cooperation activities to combat drug trafficking. Within the framework of CIS, the necessary legislative and organ ...
1-Renal excretion of drugs
1-Renal excretion of drugs

clinical guidelines for the management of hypertension
clinical guidelines for the management of hypertension

... care level as part of the Ministry of Health’s endeavour to improve and standardise the diagnosis, management and follow up of patients suffering from non-communicable diseases. The guideline has drawn on a number of reknown publications, a list of which appears at the end of the document. The devel ...
CIPROFLOXACIN
CIPROFLOXACIN

... suspension should be kept between 5 to 25°C. The suspension is good for 14 days after it is prepared. Ensure that the drug has not expired by checking the expiry date (“EXP”) shown on the outside of the package. Keep all drugs well out of the reach of children. Do not store in your bathroom. Heat an ...
Injectable Fertility Medications
Injectable Fertility Medications

... covered under a particular contract. In most cases, injectable fertility drugs used in any of these procedures also may not be covered. • These exclusions can also apply to unmanaged contracts per the NYS Infertility Mandate. • The NYS Infertility Mandate supports coverage for women 21 through 44 ye ...
Ethylcellulose Coated Multiparticulates
Ethylcellulose Coated Multiparticulates

... Figure 4 shows that for APAP layered sugar spheres, release rates are significantly decreased as molecular weight  (MW)  is  increased.  It  is  generally  known  that  tensile  strength  of  films  increases  with  MW  (Table  2),  as  longer  polymer  chains  have  greater  elasticity.  It  appear ...
COLORADO ALLERGY & ANAPHYLAXIS ACTION PLAN Unlicensed Assistive Personnel Training Handout
COLORADO ALLERGY & ANAPHYLAXIS ACTION PLAN Unlicensed Assistive Personnel Training Handout

... According to C.R.S. 25-1.5-109 parents of students with known allergies should provide documentation regarding the diagnosis and history of the student’s allergy. The parent provides this information in collaboration with the health care provider in the Allergy & Anaphylaxis Action Plan. Anaphylaxis ...
T-Class Monograph template
T-Class Monograph template

... However, it is still uncertain whether the increase in platelets is sustainable beyond 24 weeks. Clinical data from two randomized, double-blinded, placebo-controlled studies, phase II (TRA100773A: B/1/IB) and phase III (TRA100773B: B/1/IB), used to gain FDA approval for eltrombopag, support the pri ...
+ n° 6 - Octubre 2007
+ n° 6 - Octubre 2007

... individuals. Common variants in the HMGA2 oncogene, exemplified by rs1042725, were associated with height (P=4x10-8). HMGA2 is also a strong biological candidate for height because rare, severe mutations in this gene alter body size in mice and humans, so we tested rs1042725 in additional samples. W ...
HST.161 Molecular Biology and Genetics in Modern Medicine
HST.161 Molecular Biology and Genetics in Modern Medicine

... piece of information is that the SNPs mentioned are located in intron 2 of the genes of interest. Therefore, the SNPs in question are tightly linked to (in fact, located within) the genes of interest (beta globin, cftr, fgfr2, factor VIII). This means that the chances that the SNP and mutant gene ca ...
GENETICS PROBLEMS: Include the appropriate Punnett Squares to
GENETICS PROBLEMS: Include the appropriate Punnett Squares to

... 8. The x-linked barred locus in fruit flies controls the pattern of the wings, with the alleles (b) for barred pattern and (b) for no bars. A male with barred wings is mated to a nonbarred female. Complete a punnet square to show the expected genotypes and phenotypes of the offspring 9. Muscular dys ...
Ramipril - Developing Anaesthesia
Ramipril - Developing Anaesthesia

... immediately and changing to an alternative anti-hypertensive, such as methyldopa or labetalol is recommended to minimize the risk of fetal harm. Breast feeding: 4 There have been no reports following the use ramipril during breastfeeding, and the effects on the breastfed infant are unknown. Consider ...
Medication review
Medication review

... treatment OBJECTIVES: h To improve patient knowledge, concordance and use of medicines by: establishing actual use, understanding and experience of taking their medicines; identifying, discussing and resolving poor or ineffective use of their medicines; identifying side effects and drug interactions ...
Genetic Screening of Egg Donors and Male Recipients
Genetic Screening of Egg Donors and Male Recipients

... Genetic Screening of Egg Donors and Male Recipients Dear Patients of the Shady Grove Fertility Donor Egg Program, Our screening of candidates for egg donation at Shady Grove Fertility is quite extensive – in fact only ~3% of donors who apply are finally accepted to be in the donor database to cycle! ...
Slide 1
Slide 1

... The normally high concentration of DA in the basal ganglia of the brain is reduced in PD, and pharmacologic attempts to restore DA-ergic activity with levodopa and DA agonists have been successful in alleviating many of the clinical features of the disorder. An alternative but complementary approac ...
Consent to Diet Treatment - R. Jay Kohn Medical and Weight Loss
Consent to Diet Treatment - R. Jay Kohn Medical and Weight Loss

... helpful for periods far in excess of 12 weeks and at times in larger doses then those suggested in the labeling. As a physician, I am not required to use the medication as the labeling suggests, but I do use the labeling as a source of information along with my own experience, the experience of rece ...
Lorcaserin : The Serotonergic Weight Loss Medication
Lorcaserin : The Serotonergic Weight Loss Medication

... Belviq Increases Fullness and Decreases Hunger and Cravings Without Any of the Typical Weight Loss Medication Side Effects Unlike the anti-depressant SSRIs, Belviq works by controlling appetite — specifically by activating specific nerve cell receptors for serotonin in the appetite centers of the b ...
< 1 ... 531 532 533 534 535 536 537 538 539 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report