Gentamicin
... • used in the treatment of a serious infections caused by a large number of gram-negative organisms. It usually is used in combination with a second agent, because an aminoglycoside alone may not be effective for infections outside the urinary tract. • Gentamicin is of the first choice when these ...
... • used in the treatment of a serious infections caused by a large number of gram-negative organisms. It usually is used in combination with a second agent, because an aminoglycoside alone may not be effective for infections outside the urinary tract. • Gentamicin is of the first choice when these ...
Comparative study of the anesthetic efficacy of 4
... nerve is one of the locoregional anesthetic techniques most widely used in oral surgery, affording comfort and safety for both the patient and operator when used correctly. The choice of anesthetic solution should be based on three main clinical considerations: anesthetic potency, latency (time to o ...
... nerve is one of the locoregional anesthetic techniques most widely used in oral surgery, affording comfort and safety for both the patient and operator when used correctly. The choice of anesthetic solution should be based on three main clinical considerations: anesthetic potency, latency (time to o ...
Conscious sedation in children
... given in doses up to 100 mg kg21 (maximum dose 1 g), usually causes sleep within 10 min that lasts for 1 h. Its effect is variable, however, sometimes taking 60 min to sleep onset. I.V. cannulation is not necessary for oral sedation; it may be necessary for contrast media administration. † Midazola ...
... given in doses up to 100 mg kg21 (maximum dose 1 g), usually causes sleep within 10 min that lasts for 1 h. Its effect is variable, however, sometimes taking 60 min to sleep onset. I.V. cannulation is not necessary for oral sedation; it may be necessary for contrast media administration. † Midazola ...
Octreotide Acetate Injection in a prefilled syringe
... 32% of the dose is excreted unchanged into the urine. In an elderly population, dose adjustments may be necessary due to a significant increase in the half-life (46%) and a significant decrease in the clearance (26%) of the drug. In patients with acromegaly, the pharmacokinetics differ somewhat from ...
... 32% of the dose is excreted unchanged into the urine. In an elderly population, dose adjustments may be necessary due to a significant increase in the half-life (46%) and a significant decrease in the clearance (26%) of the drug. In patients with acromegaly, the pharmacokinetics differ somewhat from ...
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... checking for murmurs, including auscultation over the fontanelle as AV malformations can be diagnosed this way. Abdominal examination focuses on intra-‐ abdominal masses (liver, spleen, kidneys)(10). ...
... checking for murmurs, including auscultation over the fontanelle as AV malformations can be diagnosed this way. Abdominal examination focuses on intra-‐ abdominal masses (liver, spleen, kidneys)(10). ...
Development of a facile antibody–drug conjugate
... the latter being unstable during circulation.6 While heterogeneous ADCs have unpredictable safety and PK proles and show batch-to-batch variability, the instability of maleimide chemistry results in off-target toxicity.4 These shortcomings with current linker technologies have hindered the concept o ...
... the latter being unstable during circulation.6 While heterogeneous ADCs have unpredictable safety and PK proles and show batch-to-batch variability, the instability of maleimide chemistry results in off-target toxicity.4 These shortcomings with current linker technologies have hindered the concept o ...
Gentamicin
... • used in the treatment of a serious infections caused by a large number of gram-negative organisms. It usually is used in combination with a second agent, because an aminoglycoside alone may not be effective for infections outside the urinary tract. • Gentamicin is of the first choice when these ...
... • used in the treatment of a serious infections caused by a large number of gram-negative organisms. It usually is used in combination with a second agent, because an aminoglycoside alone may not be effective for infections outside the urinary tract. • Gentamicin is of the first choice when these ...
- Nottingham ePrints
... acquisition at a 2 s inter-stimulus-interval (ISI), suitable to detect trace conditioning impairment. However since DA is involved in reinforcement processes, the generality of effects across appetitively- and aversively-motivated trace conditioning procedures cannot be assumed. The present study te ...
... acquisition at a 2 s inter-stimulus-interval (ISI), suitable to detect trace conditioning impairment. However since DA is involved in reinforcement processes, the generality of effects across appetitively- and aversively-motivated trace conditioning procedures cannot be assumed. The present study te ...
Terbutaline Sulfate Tablets
... insufficient clinical data to establish safety and effectiveness (see DOSAGE AND ADMINISTRATION). Geriatric Use Clinical studies of terbutaline sulfate did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported ...
... insufficient clinical data to establish safety and effectiveness (see DOSAGE AND ADMINISTRATION). Geriatric Use Clinical studies of terbutaline sulfate did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported ...
studies comparing in vivo:in vitro metabolism of three
... 6-phosphate dehydrogenase, 2.5 mM nicotinamide, and 125 M NADP. The reaction was started by the addition of test compound (6 M EMD68843, 100 M EMD96785, and 1–700 M EMD128130) and terminated at times up to 1 h (for EMD68843 and EMD128130) or 2 h (for EMD96785) by addition of 450 l of the reacti ...
... 6-phosphate dehydrogenase, 2.5 mM nicotinamide, and 125 M NADP. The reaction was started by the addition of test compound (6 M EMD68843, 100 M EMD96785, and 1–700 M EMD128130) and terminated at times up to 1 h (for EMD68843 and EMD128130) or 2 h (for EMD96785) by addition of 450 l of the reacti ...
DOI: 10.1161/CIRCULATIONAHA.109.919456 published online Mar
... reversible, P2Y12 receptor antagonist, was associated with less ischemic event occurrence than clopidogrel in patients with acute coronary syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) trial. This beneficial effect may be related to more uniform and greater platelet inhibition.8 ...
... reversible, P2Y12 receptor antagonist, was associated with less ischemic event occurrence than clopidogrel in patients with acute coronary syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) trial. This beneficial effect may be related to more uniform and greater platelet inhibition.8 ...
Sacubitril / Valsartan salt complex
... aldosterone. ACE inhibitors block the deleterious effects of angiotensin II and, usually combined with a diuretic, they have formed the basis of treatment for many years. Additional complementary therapies include beta-blockers and aldosterone antagonists (MRAs). ACEIs are recommended as first-line ...
... aldosterone. ACE inhibitors block the deleterious effects of angiotensin II and, usually combined with a diuretic, they have formed the basis of treatment for many years. Additional complementary therapies include beta-blockers and aldosterone antagonists (MRAs). ACEIs are recommended as first-line ...
EFFECT OF CARVEDILOL ON THE PHARMACOKINETICS AND PHARMACODYNAMICS OF GLIPIZIDE Research Article
... vascular endothelium are commonly associated with diabetes 5. ...
... vascular endothelium are commonly associated with diabetes 5. ...
LIPOPHILICITY с METHODS OF DETERMINATION AND ITS ROLE
... principal importance in drug discovery and development. It affects three phases of drug activity ñ its pharmaceutical, pharmacokinetic and pharmacodynamic action. In this paper, a complex nature of the lipophilicity, understanding of its importance for biological activity and experimental methods of ...
... principal importance in drug discovery and development. It affects three phases of drug activity ñ its pharmaceutical, pharmacokinetic and pharmacodynamic action. In this paper, a complex nature of the lipophilicity, understanding of its importance for biological activity and experimental methods of ...
Vitamin K and osteoporosis – facts and myths
... Currently, another clinical study is underway, namely JOINT-03 (Japanese Osteoporosis Intervention Trial-03) (59), to which 1820 patients were qualified and divided into 2 equal groups. The first group receives risedronate (2.5 mg/day or 17.5 mg/week) and the other is on combined therapy with the ab ...
... Currently, another clinical study is underway, namely JOINT-03 (Japanese Osteoporosis Intervention Trial-03) (59), to which 1820 patients were qualified and divided into 2 equal groups. The first group receives risedronate (2.5 mg/day or 17.5 mg/week) and the other is on combined therapy with the ab ...
micronization and dissolution enhancement of norethindrone
... minutes and this led an impetus to search for an appropriate formulation that can give better dissolution profile. Mechanical methods of micronization are simple, efficient and cost effective way of achieving particle size reduction. The formulation developed using micronized Norethindrone produced ...
... minutes and this led an impetus to search for an appropriate formulation that can give better dissolution profile. Mechanical methods of micronization are simple, efficient and cost effective way of achieving particle size reduction. The formulation developed using micronized Norethindrone produced ...
Colchicine for pericarditis: hype or hope? REVIEW Massimo Imazio , Antonio Brucato
... useful in acute pericarditis (class IIa recommendation in European guidelines).10 In the guidelines, the recommended dose is 2 mg/day for 1–2 days, followed by a maintenance dose of 1 mg/day. However, several authors recommend that colchicine should be administered to patients with two or more relap ...
... useful in acute pericarditis (class IIa recommendation in European guidelines).10 In the guidelines, the recommended dose is 2 mg/day for 1–2 days, followed by a maintenance dose of 1 mg/day. However, several authors recommend that colchicine should be administered to patients with two or more relap ...
Albuterol Sulfate Inhalation Solution 0.5%
... Solution can produce paradoxical bronchospasm, which may be life threatening. If paradoxical bronchospasm occurs, Albuterol Sulfate Inhalation Solution should be discontinued immediately and alternative therapy instituted. It should be recognized that paradoxical bronchospasm, when associated with i ...
... Solution can produce paradoxical bronchospasm, which may be life threatening. If paradoxical bronchospasm occurs, Albuterol Sulfate Inhalation Solution should be discontinued immediately and alternative therapy instituted. It should be recognized that paradoxical bronchospasm, when associated with i ...
Optimal dosing strategies for maximising the clinical response to
... placebo (all doses); b includes diarrhoea, dyspepsia, nausea and anorexia (abdominal pain was classified as a ‘whole body’ adverse event). ...
... placebo (all doses); b includes diarrhoea, dyspepsia, nausea and anorexia (abdominal pain was classified as a ‘whole body’ adverse event). ...
10 Rocuronium for Tracheal Intubation
... acetylcholine that maintain muscle tone and the large quantities of acetylcholine that produce voluntary muscle contraction, but does not alter the resting electrical potential of the motor endplate or cause muscle contraction.1-3,5 Indications Rocuronium is approved by the Food and Drug Administrat ...
... acetylcholine that maintain muscle tone and the large quantities of acetylcholine that produce voluntary muscle contraction, but does not alter the resting electrical potential of the motor endplate or cause muscle contraction.1-3,5 Indications Rocuronium is approved by the Food and Drug Administrat ...
WARNINGS - Boehringer Ingelheim
... Distribution: The mean apparent volume (Vβ) of ketorolac tromethamine following complete distribution was approximately 13 liters. This parameter was determined from single-dose data. The ketorolac tromethamine racemate has been shown to be highly protein bound (99%). Nevertheless, plasma concentrat ...
... Distribution: The mean apparent volume (Vβ) of ketorolac tromethamine following complete distribution was approximately 13 liters. This parameter was determined from single-dose data. The ketorolac tromethamine racemate has been shown to be highly protein bound (99%). Nevertheless, plasma concentrat ...
Carbamazepine ER Capsules, 300 mg 120 count
... measurement of drug serum levels may aid in determining the cause of toxicity when more than one medication is being used. ...
... measurement of drug serum levels may aid in determining the cause of toxicity when more than one medication is being used. ...
DICETEL PM
... If you miss the usual time for taking a DICETEL tablet, take it as soon as possible. If however, it is near the time of your next dose, skip the missed pill and return to your usual dosing schedule. Do not take double the dose. What if you take too many tablets? In case of drug overdose, contact a h ...
... If you miss the usual time for taking a DICETEL tablet, take it as soon as possible. If however, it is near the time of your next dose, skip the missed pill and return to your usual dosing schedule. Do not take double the dose. What if you take too many tablets? In case of drug overdose, contact a h ...
Martindale: The Complete Drug Reference
... Aspirin-sensitive asthmatic patients have developed reactions (rhinorrhoea, tightness of chest, wheezing, dyspnoea) when challenged with diclofenac in doses of 10 to 25 mg1 and the UK CSM has received a report of an aspirinsensitive patient who died from acute asthma 4 hours after a single 25-mg dos ...
... Aspirin-sensitive asthmatic patients have developed reactions (rhinorrhoea, tightness of chest, wheezing, dyspnoea) when challenged with diclofenac in doses of 10 to 25 mg1 and the UK CSM has received a report of an aspirinsensitive patient who died from acute asthma 4 hours after a single 25-mg dos ...