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RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES KARNATAKA
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES KARNATAKA

... 6.1 Need for studyAyurvedic and Modern Science of Medicine have recognized the importance of Yakrt (liver). Ayurveda consider it as one among the Kosthangas. It is stated to be the seat of ranjaka pitta and root of raktavahasrotas. It takes part in various metabolic activities and Bhutagnipaka. The ...
Maximizing the Use of Single
Maximizing the Use of Single

... • Intended to protect patients from life-threatening infections when vials become contaminated from unsafe injection practices – include, but are not limited to, reuse of syringes for multiple patients or to access shared medications, administration of medication from a singledose/single-use vial to ...
Mefenamic Acid Capsules USP Rx Only Cardiovascular Risk
Mefenamic Acid Capsules USP Rx Only Cardiovascular Risk

... occur without warning symptoms, patients should be alert for the signs and symptoms of chest pain, shortness of breath, weakness, slurring of speech, and should ask for medical advice when observing any indicative sign or symptoms. Patients should be apprised of the importance of this follow-up (see ...
Inhalants - Addictions Foundation Manitoba
Inhalants - Addictions Foundation Manitoba

... What are inhalants? Inhalants are toxic substances found in a variety of readily available household or commercial products. Some people abuse them because, when the vapors are inhaled, they have a psychoactive effect.1,2 They are considered to be central nervous system depressants and are in the cl ...
Monitoring of Liver Function Tests in Patients - PCSS-MAT
Monitoring of Liver Function Tests in Patients - PCSS-MAT

... Naltrexone (NTX) is an opioid receptor antagonist that blocks the reinforcing effects of opioids and reduces alcohol consumption and craving. Naltrexone can be administered orally daily, or once a month by intramuscular injection (extended-release naltrexone: XR-NTX). The oral form of naltrexone (Re ...
depression - Australian Doctor
depression - Australian Doctor

... Patients with depression can also exhibit symptoms of anxiety, and these may have a negative flavour, such as worrying excessively about the future, finances or physical health. Irritability and a ‘short fuse’ are also common. Patients may complain of loss of energy or motivation to perform tasks, w ...
PDF
PDF

... Emergence of Ph-negative clones with aberrant karyotypes under continuous imatinib therapy gives rise to the speculation that tyrosine kinase inhibitors themselves may trigger induction of genetic instability. As this adverse effect may be directly proportional to the drug’s therapeutic potency, thi ...
genetic counselling in psychiatry : scope and challenges.
genetic counselling in psychiatry : scope and challenges.

... of the many receptor subtypes that exist for each neurotransmitter. For example, the neurotransmitter serotonin has at least 14 different known subtypes of receptors. Neurotransmitter receptors initiate complex signaling cascades within nerve cells. These cascades process information, produce immedi ...
Drugs for constipation and Diarrhoea
Drugs for constipation and Diarrhoea

... stool, accumulates fluids and fatty substance thus softening the stool. • Administered orally or as retention enema. • Should not be given with liquid paraffin, because increase absorption of it. ...
Retrospective Cohort Study of Diabetes Mellitus and
Retrospective Cohort Study of Diabetes Mellitus and

... treated with atypical antipsychotics are less common.15 Nevertheless, an issue has been raised recently regarding the safety of both conventional and atypical antipsychotics, as it has been suggested that their use could be associated with induction of insulin resistance and an increased risk of typ ...
Heart Failure:
Heart Failure:



... BEEN INFORMED OF THE POTENTIAL HAZARDS. If the patient becomes pregnant while taking this drug, therapy should be discontinued and the patient apprised of the potential hazard to the fetus. WARNINGS: Liver Dysfunction — HMG-CoA reductase inhibitors, like some other lipid-lowering therapies, have bee ...
Canine Coat Colour Test
Canine Coat Colour Test

... dogs, however it may become obvious for a period of time if they fade to grey as they age. The EM allele has been characterised genetically. Brown or Chocolate (B,Bs,Bc,Bd) The brown or chocolate phenotype is caused by modifications to the Tyrosinase Related Protein 1 (TYRP1) gene or the B locus. Th ...
Induced Nausea and Vomiting - Journal of the Advanced
Induced Nausea and Vomiting - Journal of the Advanced

... *Cyclophosphamide (<1,500 mg/m2), doxorubicin, epirubicin, carboplatin, idarubicin, ifosfamide, irinotecan, daunorubicin, or cytarabine (>1 g/m2). Schwartzberg LS, et al. Lancet Oncol 2015;16:1071-8. ...
Inflammatory markers in men with metabolic syndrome genotyped to
Inflammatory markers in men with metabolic syndrome genotyped to

... CRP, VCAM-1 and ICAM were found. The observed association between studied genetic variants and inflammatory markers was independent on BMI, blood pressure, serum lipids as well as leptin and adiponectin concentrations, because the levels of these factors were very similar in carriers of different ge ...
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Slide 1

... — Absolute probability of approval as well as comparison to similar agents ...
Document
Document

... Incompletely dominant alleles show an intermediate phenotype. For example, sickle cell heterozygotes show some sickling, but not the high level found in homozygotes. Codominance often occurs when both alleles produce functional, but different, proteins. Incomplete dominance is often a dosage effect. ...


... more sophisticated assessments, such as diary keeping, in order to identify more clearly the possible causes of anxiety symptoms. ...
GP at 6 months in between specialist reviews
GP at 6 months in between specialist reviews

... Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents aged from 6 years up to but not including 18 years of age. This shared care guideline relates to patients with ADHD whose condition is stable at hand over from the ADHD Specialist (Paediatrics/CAMHS) to primary ...


... with normal lung function, EIA could be prevented very effectively by sodium cromoglycate, but the dose required varied between patients. For patients with severe EIA, doubling the dose of ~2-adrenoceptor agonist or sodium cromoglycate, or using them in combination, was shown to be effective. Anecdo ...
Genetics
Genetics

... (hemizygous), any male receiving the recessive allele from his mother will express the trait. • The chance of a female inheriting a double dose of the mutant allele is much less than the chance of a male inheriting a single dose. • Therefore, males are far more likely to inherit sexlinked recessive ...
FORMULATION AND EVALUATION OF PH TRIGGERED IN SITU OPHTHALMIC GEL... MOXIFLOXACIN HYDROCHLORIDE  Research Article
FORMULATION AND EVALUATION OF PH TRIGGERED IN SITU OPHTHALMIC GEL... MOXIFLOXACIN HYDROCHLORIDE Research Article

... Antimicrobial efficiency studies were carried out to ascertain the biological activity of sol-to-gel systems against microorganisms. This was determined in the agar diffusion medium employing Cup plate technique. Sterile solution of marketed Moxifloxacin Hcl eye drops was used as a standard. The sta ...
SJS Fact Sheet - Stevens Johnson Syndrome Foundation
SJS Fact Sheet - Stevens Johnson Syndrome Foundation

Compounding Guidances Frequently Asked Questions
Compounding Guidances Frequently Asked Questions

... 6. Are hospitals/health systems held to the same requirements for anticipatory compounding as community pharmacies that do 503A compounding? Yes. Unless a hospital/health system meets the 3 requirements of the hospital/health system exception (e.g., distribution within a 1-mile radius, only to healt ...
ARTICLE IN PRESS
ARTICLE IN PRESS

... illegal drugs among drivers in Norwegian road traffic. Drivers of motor vehicles were selected from April 2005 to April 2006 in the south-eastern part of Norway, surrounding, but not including the capital, Oslo. A stratified two-stage cluster sampling procedure was used. In the first stage, random road ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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