• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Diphenhydramine versus nonsedating antihistamines for acute
Diphenhydramine versus nonsedating antihistamines for acute

... antihistamines, with 90% receiving diphenhydramine.6 In a similar study of insect sting–related allergic reactions, 57% of ED patients received antihistamines, with 90% receiving diphenhydramine.7 Treatment with antihistamines improves outcomes8 and therefore is necessary. Although there are many ef ...
Doc - PAGE meetings
Doc - PAGE meetings

... Julie Bertrand A-32 Penalized regression implementation within the SAEM algorithm to advance highthroughput personalized drug therapy ..................................................................................................46 Oral presentations Friday ....................................... ...
Extract from Clinical Evaluation Report: Riociguat
Extract from Clinical Evaluation Report: Riociguat

... who are not suitable for surgery (30-40%) or who have persistent PH after surgery (~30%). In these patients medical therapy is warranted. There are currently no approved pharmacotherapies for CTEPH and patients are frequently treated off-label. Anticoagulation may prevent further embolism and in sit ...
guidelines for the treatment of sleep disorders
guidelines for the treatment of sleep disorders

... psycho physiological and other insomnias. Relaxation training (progressive relaxation, autogenic training, meditation, deep breathing) can all be effective if over taught to become automatic. Two other behavioral therapies have been shown to be effective: Stimulus control and Sleep restriction thera ...
LITHIUM CARBONATE Extended-Release
LITHIUM CARBONATE Extended-Release

... A few reports have been received of the development of painful discoloration of fingers and toes and coldness of the extremities within one day of the starting of treatment with lithium. The mechanism through which these symptoms (resembling Raynaud's syndrome) developed is not known. Recovery follo ...
Epigenetic Interactions among Three dTph1
Epigenetic Interactions among Three dTph1

... the insertion is indicated by an arrow, and the direction is as given in Figure 1. The target site duplications flanking the transposon are underlined. Excision alleles are indicated with s (somatic excision) or g (germinal excision). Numbers in parentheses indicate the number of times that excision ...
Common Goat Medications and "Easy to Understand" Dosages
Common Goat Medications and "Easy to Understand" Dosages

... Safe for pregnant does; less resistance issues than ivomec More practical than approved drench, but no safety/efficacy studies to ...
Effect of Glyburide–Metformin Combination Tablet in Patients with
Effect of Glyburide–Metformin Combination Tablet in Patients with

... were observed (p < 0.001). Patients who took glyburide had a significant elevation of HbA1c at the end of treatment (0.52 ± 0.24%, p = 0018), while treatment with metformin resulted in no significant change in HbA1c (0.09 ± 0.37%, p = NS). Patients who received glyburide/metformin 2.5 mg/500 mg tabl ...
Prescribing Information
Prescribing Information

... who have been taking inhaled, short-acting beta2-agonists on a regular basis (e.g., four times a day) should be instructed to discontinue the regular use of these drugs and use them only for symptomatic relief of acute respiratory symptoms. When prescribing PERFOROMIST Inhalation Solution, the healt ...
Full-Text PDF
Full-Text PDF

... For many decades, serial analyses of routine LTs (liver tests) like ALT (alanine aminotransferase), AST (aspartate aminotransferase), ALP (alkaline phosphatase), and total bilirubin (TBIL) have traditionally been used for detection of DILI with marketed products and during clinical trials [1–3]. In ...
Oxcarbazepine
Oxcarbazepine

... Oxcarbazepine is rapidly absorbed after oral administration. Maximum plasma concentrations (Cmax; 1.05 to 1.74 mg/L) are reached within 2 hours after a single dose of oxcarbazepine 600mg taken after an overnight fast. The Cmax of MHD (5.44 to 8.85 mg/L) is reached after about 4 to 6 hours and the ar ...
Adenosine
Adenosine

... Repeat administration: If conversion of PSVT does not occur within 1-2 minutes, additional bolus injections of adenosine can be administered at incrementally higher doses, increasing the amount given by 0.05 to 0.1 mg/kg. Follow each bolus with a saline flush. This process should continue until sinu ...


... not take this medicine. The use of drugs of the tetracycline class during tooth development (pregnancy, infancy and childhood to the age of 12 years) may cause permanent discolouration of the teeth (yellow-grey-brown). This adverse reaction is more common during long-term use of the drugs but has be ...
Amstan Tablets.FH11
Amstan Tablets.FH11

... Amlodipine and Valsartan are antihypertensive compounds with complementary mechanisms to control blood pressure in patients with essential hypertension. The combination of these substances has an additive antihypertensive effect, reducing blood pressure to a greater degree than either component alon ...
Technology Assessment Program Report No. 11 A Systematic Review of Published
Technology Assessment Program Report No. 11 A Systematic Review of Published

... trials of treatment for ED published from January 1995-January 1999. It also includes results from additional sources including patient preference studies, post marketing reports, product inserts and FDA announcements. It focuses on new FDA-approved therapies for ED of greatest clinical and resource ...
Data Analytics with SNOMED CT – Case Studies
Data Analytics with SNOMED CT – Case Studies

... perform complex queries efficiently across extremely large numbers of patient records. The team at Oxford University has developed an open source triple store (i.e. ‘subject-predicate-object’) database called RDFox. RDFox is highly scalable and performant ‘Not Only SQL’ database readily distributed ...


... until the scans were completed, thus minimizing the amount of drug in the stomach. For simplicity reasons, the oropharyngeal numbers include the amount measured in the oropharynx plus the swallowed portion in the abdomen. Deposition in the mediastinum was minimal and not included in this report. ...
Synagis (palivizumab) SAMPLE CMS 1500 CLAIM FORM Box 19
Synagis (palivizumab) SAMPLE CMS 1500 CLAIM FORM Box 19

... Pregnancy Category C: Synagis is not indicated for adult usage. It is not known whether Synagis can cause fetal harm or could affect reproductive capacity when administered to a pregnant woman. Animal Data Animal reproduction studies have not been conducted. ...
The GCC Data Requirements for Human Drugs Submission Content
The GCC Data Requirements for Human Drugs Submission Content

... dissolution studies should ordinarily be provided in the clinical study reports. However, where a method is used in multiple studies, the method and its validation should only be included once in section 5.3.1.4 and referenced in the appropriate individual clinical study reports.  5.3.7 Case Report ...
catalog sheet - Sagent Pharmaceuticals
catalog sheet - Sagent Pharmaceuticals

... dioxide stimulation to a clinically significant extent in adults. Intravenous induction doses of midazolam hydrochloride depress the ventilatory response to carbon dioxide stimulation for 15 minutes or more beyond the duration of ventilatory depression following administration of thiopental in adult ...
Genetic Information on Cleft Lip and/or Palate General information
Genetic Information on Cleft Lip and/or Palate General information

... Approximately 30% of all babies with a cleft will have other congenital conditions. For this reason, it is important that each baby will have a detailed examination to rule out any other possible conditions they may have. Why has my child been born with a cleft? In most children, no single cause fo ...
Acute protection against exercise-induced bronchoconstriction by formoterol, salmeterol and terbutaline
Acute protection against exercise-induced bronchoconstriction by formoterol, salmeterol and terbutaline

... of action in terms of bronchodilation and protection against methacholine [3] or exercise-induced bronchoconstriction [4–6]. Both compounds, however, have a different onset of action with regard to bronchodilation [7] and smooth muscle relaxation [8]. The onset of action is of special interest in vi ...
Epigenetic Interactions among Three dTph1 Transposons in Two
Epigenetic Interactions among Three dTph1 Transposons in Two

... the insertion is indicated by an arrow, and the direction is as given in Figure 1. The target site duplications flanking the transposon are underlined. Excision alleles are indicated with s (somatic excision) or g (germinal excision). Numbers in parentheses indicate the number of times that excision ...
ranitidine oral
ranitidine oral

... not appear to substantially decrease the absorption of ranitidine or the mean peak plasma concentration of the drug. However, in one study, concomitant administration of 30 mL of an aluminum and magnesium hydroxides antacid (Mylanta-n®; neutralizing capacity of 150 mEq of hydrochloric acid per 30 mL ...
Comparison of Anti-Xa and Dilute Russell Viper Venom Time
Comparison of Anti-Xa and Dilute Russell Viper Venom Time

... by LC-MS-MS (Table). The Bland-Altman bias plots for all anti-Xa measurements demonstrated a negative bias, indicating that lower levels were detected by chromogenic methods, as compared with those obtained using LC-MS/ MS (Figure 1). When calibrated with the TECHNOVIEW rivaroxaban calibrator set, t ...
< 1 ... 31 32 33 34 35 36 37 38 39 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report