Eliglustat (as tartrate) - Therapeutic Goods Administration
... form. No other stable polymorphs have been observed. The drug substance specifications include limits for eight specified impurities and limits for the three other stereoisomers of eliglustat (1S, 2R), (1R, 2S) and (1S, 2S). Due to the high aqueous solubility of eliglustat tartrate, particle size is ...
... form. No other stable polymorphs have been observed. The drug substance specifications include limits for eight specified impurities and limits for the three other stereoisomers of eliglustat (1S, 2R), (1R, 2S) and (1S, 2S). Due to the high aqueous solubility of eliglustat tartrate, particle size is ...
HIGHLIGHTS OF PRESCRIBING INFORMATION These
... • ALT Elevations: Discontinue ethinyl estradiol-containing medications prior to starting VIEKIRA XR (alternative contraceptive methods are recommended). Perform hepatic laboratory testing on all patients during the first 4 weeks of treatment. For ALT elevations on VIEKIRA XR, monitor closely and fol ...
... • ALT Elevations: Discontinue ethinyl estradiol-containing medications prior to starting VIEKIRA XR (alternative contraceptive methods are recommended). Perform hepatic laboratory testing on all patients during the first 4 weeks of treatment. For ALT elevations on VIEKIRA XR, monitor closely and fol ...
National Prescribing Indicators 2015-2016
... • NICE CG181 was published in July 2014, which updates guidance relating to lipid modification in adults both with and without diabetes: – Atorvastatin, simvastatin and pravastatin are LAC statins and remain the lipidmodifying drugs of choice. – Use a statin of high intensity and low acquisition cos ...
... • NICE CG181 was published in July 2014, which updates guidance relating to lipid modification in adults both with and without diabetes: – Atorvastatin, simvastatin and pravastatin are LAC statins and remain the lipidmodifying drugs of choice. – Use a statin of high intensity and low acquisition cos ...
Fluoxetine Accord capsule, hard ENG SmPC
... mild to moderate; however, in some patients they may be severe in intensity. They usually occur within the first few days of discontinuing treatment. Generally, these symptoms are self-limiting and usually resolve within 2 weeks, though in some individuals they may be prolonged (2-3 months or more). ...
... mild to moderate; however, in some patients they may be severe in intensity. They usually occur within the first few days of discontinuing treatment. Generally, these symptoms are self-limiting and usually resolve within 2 weeks, though in some individuals they may be prolonged (2-3 months or more). ...
Newer Antiepileptic Drugs
... themselves been damaged or altered in some way.3 Therefore, although the clinical characteristics (intensity, quality, and course) of nociceptive pain are determined primarily by the physical injury causing the pain, the clinical characteristics of neuropathic pain are determined predominantly by th ...
... themselves been damaged or altered in some way.3 Therefore, although the clinical characteristics (intensity, quality, and course) of nociceptive pain are determined primarily by the physical injury causing the pain, the clinical characteristics of neuropathic pain are determined predominantly by th ...
population genetics
... The way a trait is determined by the alleles for a gene depends on how the alleles, and the proteins they make, interact with each other. Obviously, if an individual is homozygous for a gene/locus (i.e., having two of the same allele), that allele determines the trait. If an individual is heterozygo ...
... The way a trait is determined by the alleles for a gene depends on how the alleles, and the proteins they make, interact with each other. Obviously, if an individual is homozygous for a gene/locus (i.e., having two of the same allele), that allele determines the trait. If an individual is heterozygo ...
Section 1
... are controlled by factors that occur in pairs. – In his experiments on pea plants, one factor in a pair masked the other. The trait that masked the other was called the dominant trait. The trait that was masked was called the recessive trait. ...
... are controlled by factors that occur in pairs. – In his experiments on pea plants, one factor in a pair masked the other. The trait that masked the other was called the dominant trait. The trait that was masked was called the recessive trait. ...
Macula Risk - Institut Nazareth et Louis
... and detect 70% of individuals who will develop ARMD. However, the test is less reliable if the subject is non-white. Macula Risk is intended among others for people showing the first signs of AMD or those who have immediate relatives with the disease. Identifying individuals at risk would allow for ...
... and detect 70% of individuals who will develop ARMD. However, the test is less reliable if the subject is non-white. Macula Risk is intended among others for people showing the first signs of AMD or those who have immediate relatives with the disease. Identifying individuals at risk would allow for ...
Mobic Clinical Overview and what`s up with the
... Independent DSMBs for these studies with special emphasis on cardiovascular events. Both DSMB’s get monthly data updates; have issued statements to investigators that they are aware of rofecoxib W/D and have determined there is no indication for stopping these trials Meet again in late fall ...
... Independent DSMBs for these studies with special emphasis on cardiovascular events. Both DSMB’s get monthly data updates; have issued statements to investigators that they are aware of rofecoxib W/D and have determined there is no indication for stopping these trials Meet again in late fall ...
DEXAMETHASONE WITH EITHER GRANISETRON LAPAROSCOPIC SURGERY
... in the relative risk of postoperative nausea and vomiting is the best that can be expected, even when total intravenous anesthesia is used in combination with three antiemetics8. Therefore, combination therapy using antiemetics acting at different neuroreceptor sites is more effective than using ind ...
... in the relative risk of postoperative nausea and vomiting is the best that can be expected, even when total intravenous anesthesia is used in combination with three antiemetics8. Therefore, combination therapy using antiemetics acting at different neuroreceptor sites is more effective than using ind ...
ASH Times - American Society of Hypertension
... the healthcare sysis f lat and there has of the few that’s able to anticipate tem by phenotype and been contraction and events and to adjust or even modify genotype data. consolidation in big “A t t he p ol ic y pharma and in bio- those events. And, therefore, it’s im- level, support pretechnology. ...
... the healthcare sysis f lat and there has of the few that’s able to anticipate tem by phenotype and been contraction and events and to adjust or even modify genotype data. consolidation in big “A t t he p ol ic y pharma and in bio- those events. And, therefore, it’s im- level, support pretechnology. ...
FDA and the Challenge of Alternative Medicine: Realistic
... pharmacopoeia.25 Related to these medicines is the more general practice of herbal medicine, which uses a variety of herbs in various forms to prevent and treat a wide range of diseases. The medicines that should fall into Category (1) tend to be both preventive and curative in nature, but also view ...
... pharmacopoeia.25 Related to these medicines is the more general practice of herbal medicine, which uses a variety of herbs in various forms to prevent and treat a wide range of diseases. The medicines that should fall into Category (1) tend to be both preventive and curative in nature, but also view ...
full prescribing information
... 1. This medication is to be used as directed by the physician. It is for external use only. Avoid contact with the eyes, nose, mouth, and all mucous membranes. 2. This medication should not be used for any disorder other than that for which it was prescribed. 3. Patients should not use any other top ...
... 1. This medication is to be used as directed by the physician. It is for external use only. Avoid contact with the eyes, nose, mouth, and all mucous membranes. 2. This medication should not be used for any disorder other than that for which it was prescribed. 3. Patients should not use any other top ...
VICTOZA is contraindicated in patients with a personal or family history... carcinoma or in patients with Multiple Endocrine Neoplasia syndrome type... ——— CONTRAINDICATIONS ———
... hemorrhagic or necrotizing pancreatitis, has been observed in patients treated with VICTOZA®. After initiation of VICTOZA®, observe patients carefully for signs and symptoms of pancreatitis (including persistent severe abdominal pain, sometimes radiating to the back and which may or may not be accom ...
... hemorrhagic or necrotizing pancreatitis, has been observed in patients treated with VICTOZA®. After initiation of VICTOZA®, observe patients carefully for signs and symptoms of pancreatitis (including persistent severe abdominal pain, sometimes radiating to the back and which may or may not be accom ...
Diagnosis and medical treatment of lower urinary tract symptoms in
... tolterodine and solifenacin) may be used to manage storage symptoms (OAB) in men with LUTS [1]. Although the majority of patients included in clinical trials of these agents have been women, men with storage symptoms experienced similar benefits and side effects with antimuscarinics in these studies ...
... tolterodine and solifenacin) may be used to manage storage symptoms (OAB) in men with LUTS [1]. Although the majority of patients included in clinical trials of these agents have been women, men with storage symptoms experienced similar benefits and side effects with antimuscarinics in these studies ...
Introduction to the WHO Drug Dictionary
... the features, codes and nomenclature as provided by the Uppsala Monitoring Centre. The dictionary data is possible to upload into any software system for coding, reporting or analysis. Some features in the dictionary may not be included in the system you are using, or other nomenclature may be used. ...
... the features, codes and nomenclature as provided by the Uppsala Monitoring Centre. The dictionary data is possible to upload into any software system for coding, reporting or analysis. Some features in the dictionary may not be included in the system you are using, or other nomenclature may be used. ...
prescribing information
... patients who have cardiac arrhythmias, coronary artery or organic heart disease, hypertension, or in patients who are on drugs that may sensitize the heart to arrhythmias, e.g., digitalis, diuretics, quinidine, or other anti-arrhythmics. In such patients, epinephrine may precipitate or aggravate ang ...
... patients who have cardiac arrhythmias, coronary artery or organic heart disease, hypertension, or in patients who are on drugs that may sensitize the heart to arrhythmias, e.g., digitalis, diuretics, quinidine, or other anti-arrhythmics. In such patients, epinephrine may precipitate or aggravate ang ...
Data Sheet
... urine is a conjugate of 4-hydroxy-2,6-xylidine, accounting for about 70-80% of the dose excreted in the urine. The elimination half-life of lignocaine following an intravenous bolus injection is typically 1.5 to 2.0 hours. Because of the rapid rate at which lignocaine is metabolised, any condition t ...
... urine is a conjugate of 4-hydroxy-2,6-xylidine, accounting for about 70-80% of the dose excreted in the urine. The elimination half-life of lignocaine following an intravenous bolus injection is typically 1.5 to 2.0 hours. Because of the rapid rate at which lignocaine is metabolised, any condition t ...
10.26.09 Jonas RA
... Rheumatoid Arthritis: Unknown Case 52-year-old man with destructive RA treated with ...
... Rheumatoid Arthritis: Unknown Case 52-year-old man with destructive RA treated with ...
Alcohol and Other Drugs: A Handbook for Health Professionals
... This Handbook is the third edition of a resource originally produced well over a decade ago. The last edition proved to be a valuable and much sought after document. In the intervening years since the last edition of the Handbook was produced the alcohol and other drugs field has changed, expanded ...
... This Handbook is the third edition of a resource originally produced well over a decade ago. The last edition proved to be a valuable and much sought after document. In the intervening years since the last edition of the Handbook was produced the alcohol and other drugs field has changed, expanded ...
A Parallel Phase I/II Clinical Trial Design for Combination Therapies
... Wei and Durham, 1978). A disadvantage of these approaches is that it does not account for the reliability of the estimated values of Pi . The difference between, say, Pi = 0.4 and Pj = 0.5 results in the same difference in assignment probabilities throughout the trial. Consequently, these designs are ...
... Wei and Durham, 1978). A disadvantage of these approaches is that it does not account for the reliability of the estimated values of Pi . The difference between, say, Pi = 0.4 and Pj = 0.5 results in the same difference in assignment probabilities throughout the trial. Consequently, these designs are ...
Formulation, Development and Evaluation of delayed release
... Delayed release dosage forms1 are designed to release the drug at a time rather than promptly after administration. The delay may be time based or ...
... Delayed release dosage forms1 are designed to release the drug at a time rather than promptly after administration. The delay may be time based or ...
Distinguishing genotype and phenotype in genetic programming
... range of ways available to GAs. To evaluate the fitness of a genotype, GADS tests the phenotype in the environment in which it is to operate. The result of the testing gives the fitness of the phenotype, and by implication, of the underlying genotype. Using a tuple genotype has the immediate advanta ...
... range of ways available to GAs. To evaluate the fitness of a genotype, GADS tests the phenotype in the environment in which it is to operate. The result of the testing gives the fitness of the phenotype, and by implication, of the underlying genotype. Using a tuple genotype has the immediate advanta ...