• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
TO DOWNLOAD OUR Mobic INFORMATION PACKAGE
TO DOWNLOAD OUR Mobic INFORMATION PACKAGE

... risk is important as more patients take the drug, Graham said. Graham, along with other scientists outside the FDA, analyzed data culled from California's Medicaid program of more than 15,000 heart attack patients, making it the largest study to date on such risks. They found the statistical risk of ...
Pharmacology - practical courses
Pharmacology - practical courses

... Conditions for credit. Pharmacology - definition, basic terminology, subspecializations, drug nomenclature. Introduction to the prescription terminology. Classification of drug preparations. Pharmacopoea. /2/ INTRODUCTION TO THE PHARMACOKINETICS Transfer of drugs across biological membranes. Basic p ...
presentation here
presentation here

...  Expensive (Drug cost – 5 thousand)  Clinical & lab. Monitoring is required ...
atomoxetine - DavisPlus
atomoxetine - DavisPlus

... Absorption: Well absorbed following oral administration. Distribution: Unknown. Protein Binding: 98%. Metabolism and Excretion: Mostly metabolized by the liver (CYP2D6 enzyme pathway). A small percentage of the population are poor metabolizers and will have higher blood levels withqeffects. Half-lif ...
Etotio
Etotio

... adjustment is required in this group of patients, etodolac clearance is dependent on liver function and dose can be decreased in patients with severe liver failure. Pediatric population: It is not used in patients younger than 16 years of age due to safety reasons. Geriatric population: The risk for ...
Drug Abuse and the Dialysis Patient
Drug Abuse and the Dialysis Patient

... Some individuals stop drug abuse through a religious experience or realization. ...
06_prughNS
06_prughNS

... Selective agents (weather events, predators, competitors) favor one form of a trait over another (larger beaks, longer legs, stronger horns) ...
SECTION 2
SECTION 2

... – The science of drugs, including their ingredients, preparation, uses and actions on the body • Dose – Amount of medication given • Action – Therapeutic effects expected on the body ...
Pharmacokinetics and pharmacodynamics
Pharmacokinetics and pharmacodynamics

... • Blood from the GI tract and the rest of the body flows through the liver. Drugs excreted by the liver diffuse into hepatocytes and then enter the bile (changed or unchanged). • Bile is collected in the gallbladder and then dumped into the duodenum. • Lipophilic drug molecules have the opportunity ...
Medicinal chemistry
Medicinal chemistry

... discipline, involving aspects of biological, medical and pharmaceutical sciences. It is concerned with the invention, discovery, design, identification and preparation of biologically active compounds, the study of their metabolism, the interpretation of their mode of action at the molecular level a ...
metoprolol (me-toe-proe-lole) - DavisPlus
metoprolol (me-toe-proe-lole) - DavisPlus

... Why was this drug prescribed for your patient? ...
Logan Rayborns Biology CrosswordsM
Logan Rayborns Biology CrosswordsM

... 3. dominance a form of intermediate inheritance in which one allele for a specific trait is not completely expressed over its paired allele. 4. assortment formation of random combinations of chromosomes in meiosis and of genes on different pairs of homologous chromosomes by the passage according to ...
Antiparasitic
Antiparasitic

... Suramin is a sulfated naphthylamine that was introduced in the 1920s. It is the first-line therapy for early hemolymphatic African trypanosomiasis. It does not enter the central nervous system, The drug's mechanism of action is unknown. It is administered intravenously and displays complex pharmacok ...
street drugs, poisoning & overdose
street drugs, poisoning & overdose

... By the early 1980s, MDMA was being promoted as “the hottest thing in the continuing search for happiness through chemistry,” and the “in drug” for many weekend parties. Still legal in 1984, MDMA was being sold under the brand name “Ecstasy,” but by 1985, the drug had been banned due to safety concer ...
Complexities of Warfarin Therapy May Lead to Increased Resource
Complexities of Warfarin Therapy May Lead to Increased Resource

... 1. Fuster V, Rydén LE, Cannom DS, et al. 2011 ACCF/AHA/HRS focused updates incorporated into the ACC/ AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guideline ...
warfarin (war-fa-rin) - DavisPlus
warfarin (war-fa-rin) - DavisPlus

... controlled hypertension; OB: Crosses placenta and may cause fatal hemorrhage in the fetus. May also cause congenital malformation. Use Cautiously in: Malignancy; Patients with history of ulcer or liver disease; History of poor compliance; Women with childbearing potential; Asian patients or those wh ...
Improve Monitoring and Compliance Activities Surrounding Off
Improve Monitoring and Compliance Activities Surrounding Off

... and send clear message when new media approach does not comply with regulations Social media will be treated like other comparable promotional material DTC Guidance Documents have been developed and enforcement actions sent but true internet guidance is unlikely ...
XomeDx - GeneDx
XomeDx - GeneDx

... The purpose of this test is to identify the underlying molecular basis of a genetic disorder in an affected individual who has exhausted all other currently available genetic testing options. Knowledge of important genetic information will allow the physician to accurately assess the prognosis and w ...
CHOOSE THE SINGLE BEST ANSWER
CHOOSE THE SINGLE BEST ANSWER

... 39. Eplerenone acts as a specific A. antagonist of the mineralocorticoid receptor B. antagonist of the renin receptor C. agonist of the AT2 receptor D. agonist of the ADH V1 receptor E. antagonist of the NCC co-transporter 40. In contrast to tricyclic antidepressants (TCA), selective serotonin reup ...
drugs associated with increased fall risk
drugs associated with increased fall risk

... Note:Some patients may take various combinations of the antihypertensive drugs mentioned above. ...
Teaching health professionals about complementary and alternative
Teaching health professionals about complementary and alternative

... side-effects from medication prescribed during their stay in hospital has dropped by more than half over the past four years, a project at the Sydney Children's Hospital has found. But despite the improvements, almost nine out of every 100 pediatric patients prescribed drugs during their stay in hos ...
Diagnostic approach in patients with hypersensitivity
Diagnostic approach in patients with hypersensitivity

... NSAIDs, paracetamol and local anesthetics. Since only two patients developed anaphylaxis as the only severe reaction observed during 243 challenges, they concluded that drug provocation tests are safe. It has to be mentioned that in this study most patients were challenged with alternative drugs mor ...
presentation source - NAU jan.ucc.nau.edu web server
presentation source - NAU jan.ucc.nau.edu web server

... percentage of the drug is changed from the original mother compound into some intermediate metabolite. All of the drug then passes out into the systemic circulation as 1) the intact drug plus its 2) changed intermediates. ...
policy - Hertford County Public Health Authority
policy - Hertford County Public Health Authority

... admixtures or other medications, in the patient’s home, except when it is not feasible, e.g., in pre-filling insulin syringes or when the medication’s stability is short. 2. If preparing chemotherapeutic medications for initial or ongoing administration, staff will utilize appropriate protective equ ...
Drugs Interactions May 2010
Drugs Interactions May 2010

... drugs and these affect the metabolism of other drugs reducing their concentration and hence effect. • e.g oral contraceptive metabolism is enhanced if Phenytoin is co-administered ,leading to unplanned pregnancy ...
< 1 ... 1204 1205 1206 1207 1208 1209 1210 1211 1212 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report