• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Special considerations for age groups
Special considerations for age groups

... • Problems which interfere with appetite, balance, energy and lead to dehydration, weight loss, falls and immobility. ...
vol.13 No.2 - TU Teaching Hospital
vol.13 No.2 - TU Teaching Hospital

... Meals and medicines Understanding the possible clinical implications of taking medicines with or without a meal is important for achieving quality use of medicines. Although the effect of food is not clinically important for many drugs, there are food-drug interactions which may have adverse consequ ...
High Risk Medication Therapeutic Alternatives Guide
High Risk Medication Therapeutic Alternatives Guide

... with clinnically significant elevated serum creatin nine due to  paired excretio on. Elderly  increaseed risk of toxiccity from imp acrodantin® o or Macrobid® (nitrofuranto oin) patients have higher risk of develo Furaadantin®, Ma oping acute, ssubacute  ...
12 Why are the elderly often overdosed?
12 Why are the elderly often overdosed?

... of medications. The Centers for Disease Control and Prevention estimate that almost 94 percent of those ages 75 to 84 received a prescription medication in ...
The Slippery Slope of Relieving Pain: Be Wary of Opioid Drugs
The Slippery Slope of Relieving Pain: Be Wary of Opioid Drugs

... These patients make up about 20 percent of all prescription drug overdoses. Patients in this group often suffer from chronic pain (from such diseases as arthritis, cancer, chronic back pain, or fibromyalgia). They may also be older Americans, who often have more than one health condition. These pers ...
Introduction to BST775: Statistical Methods for Genetic Analysis I
Introduction to BST775: Statistical Methods for Genetic Analysis I

... • How DNA is inherited ...
HST-150/151 Mid
HST-150/151 Mid

... It gets metabolized by alcohol dehydrogenase to nasty metabolites like glycolic acid and oxalate. These can cause acidosis and renal failure. Toxic effects may be minimized by inhibiting alcohol dehydrogenase with a competitive substrate (ethanol) or a direct antagonist (fomepizole). 14. Which of th ...
before
before

... Multi-dose Vial ...
Newsletter
Newsletter

... the detrusor smooth muscle of the urinary bladder to relax during the storage phase of the fill-void cycle to increase bladder capacity. Other agents available for the treatment for OAB include Detrol® (tolterodine), Enablex® (darifenacin), and VESIcare® ...
Personal Health 2002 Chapter 5 Human Sexuality
Personal Health 2002 Chapter 5 Human Sexuality

... The Risks of Ecstasy ...
LOs Parmicokinetics 5 - 8 - PBL-J-2015
LOs Parmicokinetics 5 - 8 - PBL-J-2015

... The degree to which a drug binds with a protein will impact upon the availability of that drug and hence its action. Drugs that are strongly protein-bound stay mainly in the plasma compartment. ...
Problemset 6
Problemset 6

... these drugs. Leuprorelin, if given as pulse, stimulates FSH and LH release => ovulation. Clomiphene blocks the negative feed-back of estrogens on the hypothalamus and anterior pituitary gland => FSH and LH release => ovulation. 5) Which of the following drugs can interfer with the effects of oral co ...
Progressive Myoclonus Epilepsy - broader panel
Progressive Myoclonus Epilepsy - broader panel

... and affirm that my patient (Alternative: authorized representative, if a minor) has provided informed consent for genetic testing. A positive test result would confirm a genetic diagnosis and would ensure my patient is being managed appropriately. I am specifying Ambry Genetics Corporation because t ...
This abstract is not connected to an organized session. Biography
This abstract is not connected to an organized session. Biography

Genetics offers route to cure TB - FT.com
Genetics offers route to cure TB - FT.com

... where TB recurs after treatment. Until now, it has been hard for doctors to establish whether a patient has suffered a relapse of the original infection or picked up a new infection with a different strain. Genome sequencing gives the answer, which is important for managing the disease. “What surpri ...
Today's biomedical innovation: lost in translation
Today's biomedical innovation: lost in translation

... efficacy) before it goes on the market • Even after an expenditure of $1B per successful drug, multiple important clinical questions remain unanswered (e.g. dose and regimen, use with other therapies, optimal duration of therapy, consequences of long-term use) • Academic clinical community constantl ...
Jeremy Gruber - PowerPoint - Personlaized Medicine
Jeremy Gruber - PowerPoint - Personlaized Medicine

... Different DTC companies offer different results for identical samples 1) DTC tests are not federally approved or validated. 2) Reliability has not been certified and standardization has not been set by a professional ...
Pharmacist Activist T
Pharmacist Activist T

... Therapeutics) is the first drug to be approved for the treatment of chronic angina in more than a decade, and its structural and pharmacologic characteristics differ from those of the long-acting nitrates (e.g., isosorbide mononitrate [e.g., Imdur]), beta-blockers (e.g., atenolol [e.g., Tenormin]) an ...
NEWS YOU CAN USE 2015 12 UPD
NEWS YOU CAN USE 2015 12 UPD

... and long acting anticholinergic • 12-week efficacy studies showed superior and sustained improvements in lung function 10/30/2015 Medscape.com ...
NEWS YOU CAN USE 2014 08 UPD
NEWS YOU CAN USE 2014 08 UPD

... • It will be available as the 50mcg per spray ...
Document
Document

... preference information and two with criteria rankings elicited from an expert in the field of antidepressants. We explained the SMAA model and multi-attribute utility theory to the expert and asked her to consider two scenarios: mild and severe depression. ...
What is genetic engineering?
What is genetic engineering?

... Genetic engineering could also change the genes in the embryo – they could stop children being born with genetic defects such as cystic fibrosis. ...
WHAT TREATMENT OPTIONS ARE AVAILABLE TO ME?
WHAT TREATMENT OPTIONS ARE AVAILABLE TO ME?

... patients vulnerable to gastrointestinal bleeding. This occurs when the NSAIDs trigger an increase in stomach acid, while also reducing the stomach’s normal protective mucus layer. Those patients with high blood pressure, heart disease, pre-existing kidney disease, people taking water pills and peop ...
CHEMICAL MESSENGERS
CHEMICAL MESSENGERS

... mouth’s mucous membranes ...
Drug Interactions
Drug Interactions

... • What possible interactions are there ? • Where can you find information on this interaction ? • Are there any case reports in the literature ? • How would you find these case reports ? ...
< 1 ... 1199 1200 1201 1202 1203 1204 1205 1206 1207 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report