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8-Anti-mycobacterial drugs

... Anti-inflammatory and Immunologic effects may be responsible for its efficacy in the prevention and treatment of Erythema Nodosum Leprosum, a type II hypersensitivity reaction seen during or after the treatment of Lepromatous Leprosy. The drug has a long half-life (about 70 days) and some of it rem ...
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... explain complaints Disproportionate physical disability Dramatic use of appliances Dramatic expressions of pain Inconsistent responses to testings Spontaneous movements better than when formally tested ...
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... offspring is called a population - These individuals share a gene pool, all the genes and alleles for each gene in a population ...
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... The mainstay of treatment is necessarily supportive and each symptom is managed on an individual basis. In general, affected patients eventually require assisted living arrangements or care in a nursing home. The exact biochemical basis of AD is not well understood. Deficiencies of the brain choline ...
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... Overall for patients, the benefits of pharmacogenomics are more effective disease treatment and management; better, safer medications the first time; more accurate determination of appropriate dosages; and the potential for decreased overall cost of health care. For providers, there are also numerou ...
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... 14. Before the passage of this act, any narcotic could be purchased without a prescription. A) Pure Food and Drug Act B) Pure Food, Drug, and Cosmetic Act C) Harrison Narcotic Act D) Comprehensive Drug Abuse Prevention and Control Act ...
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Document
Document

... mood, relaxing you or even giving you more energy. However, they can also have negative impacts on your mental and physical health, your relationships, and your life in general. • If you are taking drugs, it is possible you believe that you can manage the effects of the drugs and that • you can deal ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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