• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
ASRA-005-Final
ASRA-005-Final

... Introduction: Intravenous patient-controlled analgesia (IV PCA) with morphine is the standard of care in many hospitals for the management of acute post-operative pain. However, IV PCA is associated with several limitations, including, the risk of PCA pump programming errors, reduced patient mobilit ...
Pain Management clinical protocol MMC.docx
Pain Management clinical protocol MMC.docx

... Frequency of administration: 4-6 hourly, max 4G in 24 hours ...
accelerated pathways: global opportunities and
accelerated pathways: global opportunities and

... To begin, it is critical to target the right indication with the right drug, understanding that the aim must be an unmet medical need. A condition with little morbidity, where effective treatment options are available, will likely not qualify for an AP anywhere in the world. Conversely, a drug for a ...
Assignment #1
Assignment #1

... pairs of chromosomes(4) separate and segregate(5) randomly during cell division to produce gametes(6) containing one chromosome of each type. b. Only certain cells in a multicellular(7) organism undergo meiosis. c. Random chromosome segregation explains the probability that a particular allele(8) wi ...
variation
variation

...  A gamete is a sex cell  Each gamete contains one set of genes on its chromosomes  Each organism receives two copies of each gene (one from the gamete of each parent)  Alleles are different versions of a gene that contain different instructions for a characteristic  The particular version of a ...
pharm tech 2016-2017 class 2 ch 7 thru 13
pharm tech 2016-2017 class 2 ch 7 thru 13

... O Multiple testing centers across the U.S. ...
zzz - pharm 1st retake 2010.1 - SAMIT - kasiula264
zzz - pharm 1st retake 2010.1 - SAMIT - kasiula264

... 23. Which of the following statements correctly pairs a commonly used anticoagulant with its MOA? a. ...
Use of real-time clinical surveillance decision support software as a
Use of real-time clinical surveillance decision support software as a

... • ADEs have long been recognized as a major cause of morbidity and mortality for hospitalized patients. • Incidence of ADEs vary in the literature depending on the definitions and methods of measurement. • Conventional methods to quantify ADEs include voluntary reporting and retrospective medical re ...
Aller-Chlor - DavisPlus
Aller-Chlor - DavisPlus

... Subcut, IM, IV (Adults): 5– 40-mg single dose (not to exceed 40 mg/day). Subcut (Children): 87.5 mcg (0.0875 mg)/kg or 2.5 mg/m2 q 6 hr as needed. ...
Medicines additional questions LT Scotland
Medicines additional questions LT Scotland

... Identify the pharmacophore that is responsible for the pain killing effect. ...
Pharmacology PT020D - Porterville College Home
Pharmacology PT020D - Porterville College Home

... facilitates elimination of drug metabolites. ...
Student Clinical Digest - University of Georgia College of Pharmacy
Student Clinical Digest - University of Georgia College of Pharmacy

... Brittany Thompson, Pharm.D. Candidate The advances made in antibiotic treatments made since the introduction of penicillin in the 1940s have been vastly beneficial for patients. However, taking antibiotics when unwarranted (such as in viral infections) or not taking the entire course of the antibiot ...
McPherson Substance Abuse and Pain Management
McPherson Substance Abuse and Pain Management

... – A primary, chronic, neurobiologic disease, with genetic, psychosocial, and environmental factors, influencing its development and manifestations. – It is characterized by behaviors that include onr or more of the following: ...
Introduction To Pharmacology
Introduction To Pharmacology

... drug on the body, including receptor interactions, dose-response phenomena, and mechanisms of therapeutic and toxic action. • F. Pharmacokinetic properties describe the action of the body on the drug, including absorption, distribution, metabolism, and excretion. • Elimination of a drug may be achie ...
Slide 1
Slide 1

... because the patients weren't taking it and not because the drug didn't work, an analysis of the study results suggests. • A subsequent analysis of urine samples retained from the study showed that fewer than 40 percent of 53 patients in the vigabatrin arm who completed the 12-week study had urine dr ...
教案编写基本格式与要求
教案编写基本格式与要求

... produce their effects by binding with their specific receptors. • Aluminium hydroxide and magnesium trisilicate, which are used in the treatment of peptic ulcer disease act by non-receptor mechanism by neutralizing the gastric acid. Many drugs are similar to or have similar chemical groups to the na ...
Drug Facilitated Sexual Assault
Drug Facilitated Sexual Assault

... practice 7/16/09 – revise as appropriate to reflect current standards of care.) ...
5.2- Studying Genetic Crosses
5.2- Studying Genetic Crosses

... Genetic Crosses SBI 3U1- Ferrari ...
Assessing Drug Substances to Identify “Highly Hazardous
Assessing Drug Substances to Identify “Highly Hazardous

... contamination acceptable by unintended exposure If we can clean to an acceptable level that is measurable, then dedication / segregation not needed Certain categories of drugs still cause concern due to poorly defined terms and poor understanding of risks. Although the tide is turning, some regulato ...
LESSON 5.6 WORKBOOK What are the long-term effects of drug
LESSON 5.6 WORKBOOK What are the long-term effects of drug

... Additionally, learning may also be involved in relapse. Conditioning is one example of this type of learning and memory, in which environmental cues become associated with the drug experience and can trigger uncontrollable cravings if the individual is later exposed to these cues, even without the d ...
dfdfdfdfd
dfdfdfdfd

... Three of the drugs belong to the so-called ‘2C’ family and are from the phenethylamine chemical group. All provoke hallucinogenic and other effects such as mood-lifting, sense of well-being and powerful visual alterations. The substances tend to be taken in doses ranging from 10–35 mg, thus being st ...
genetics
genetics

... •MEDICAL GENETICS -Application of knowledge of human genetics for the practice of medicine and medical research ...
How the FDA Manages Drug Safety With Black Box Warnings, Use
How the FDA Manages Drug Safety With Black Box Warnings, Use

... manufacturer to send a “Dear Healthcare Professional” letter outlining safety issues with advice for corrective action. A medication guide, an instruction sheet provided to the patient by the pharmacist, may be used. If these educational strategies are inadequate, additional management tools are req ...
Post-mortem SNP analysis of CYP2D6 gene reveals correlation
Post-mortem SNP analysis of CYP2D6 gene reveals correlation

... (Group 2, n ¼ 16), and three or more copies of functional alleles (Group 3, n ¼ 4). Distribution of alleles corresponds roughly to that found in the random Caucasian population [6,18], although slight overpresentation of UM genotypes (12% versus 1–5% in Caucasians) and consequent deviation in other ...
Algorithm for Treating Epilepsy Patients with Valproate (Depakote
Algorithm for Treating Epilepsy Patients with Valproate (Depakote

... Initiate dose at 15mg/kg/day in divided doses Increase by 250-500 mg/day per week to an initial maintenance dose of ~ 40-60mg/kg/day (target concentration 50-100mcg/ml ) Inhibits the cytochrome P-450 enzymes and monitoring of concommitant drug therapy is advised. Caution should be with lamotrigine a ...
< 1 ... 1173 1174 1175 1176 1177 1178 1179 1180 1181 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report