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Alcohol & Marijuana: Impact on the Body
Alcohol & Marijuana: Impact on the Body

... Taking drugs prescribed to someone else Using old, unfinished prescriptions to treat a condition for which the drug was not originally ...
Nursing 3703 Pharmacology in Nursing
Nursing 3703 Pharmacology in Nursing

... 3. 3rd is by carrier proteins that transport molecules from one side of the cell membrane to the other. An example would be oral drugs that carry hormones to their sites of action (see text for details) ...
September 2006
September 2006

... stated that mothers with the lowest levels of Vitamin E intake had children whose risk for asthma or wheezing by age five was FIVE times greater than those in the highest intake group. The children’s own E intake apparently did not change the associated risk.  The secret to long life is not all in ...
Roles of Different Neurotransmitters
Roles of Different Neurotransmitters

... neurotransmitter;  the brain, producing migraines or  involved in memory seizures; this is why some people  avoid MSG (monosodium  glutamate) in food ...
Born Hooked
Born Hooked

... Drug Affected Newborns ...
Drugs and the Law
Drugs and the Law

... The “War on Drugs” is marred by racial overtones. For example, Blacks comprise less than 15% of the population but comprise 32% of those arrested for drugs. There are disparities in drug sentencing depending on race and even type of drug involved in the offense ...
Marketing: ASHP Policy Positions
Marketing: ASHP Policy Positions

... Public health researchers have characterized the U.S. experience with direct-toconsumer advertising (DTCA) of prescription drugs since 1997 as “a large and expensive uncontrolled experiment in population health, which to date shows decidedly mixed effects.” 1 Those researchers and others2,3,4,5 have ...
Genetic Equilibrium Honors Biology Mr. Lee Room 320
Genetic Equilibrium Honors Biology Mr. Lee Room 320

... (group of individuals of the same species that interbreed)  Gene pool- consists of all the genes, and alleles, that are present in a population  Relative frequency of an alleles is the number of times that an allele occurs in a gene pool ...
Guide to using the PCR lab File
Guide to using the PCR lab File

... protein and the ability to metabolise certain prescription drugs. CYP2D6 gene analysis The segments of genetic code for the CYP2D6 protein are found in nine exons and the final spliced version of the RNA is called messenger RNA (mRNA). If the bases at or near the sites of splicing are mutated in any ...
Drug Interactions
Drug Interactions

... has toxic effects on the same organ, can greatly increase the likelihood of organ damage. For example, concurrent administration of two nephrotoxic drugs can produce kidney damage even though the dose of either drug alone may have been insufficient to produce toxicity. Furthermore, some drugs can en ...
Human genomics
Human genomics

ECSTASY
ECSTASY

... increased heart rate, muscle spasms, and convulsions. It can make you feel paranoid, hostile and anxious even when not high. It increases the rate of heart attack, stroke, seizure, and respiratory failure, any of which can result in sudden death. ...
Indication Important Safety Information
Indication Important Safety Information

2006 Theories of Addiction
2006 Theories of Addiction

... Addiction is chronic, progressive, relapsing, incurable & potentially fatal.  Genetic irregularities in the brain chemicals  Drug use in an environment that is conducive to drug misuse , loss of control and compulsive use follow ...
Anti-psychotic Treatment
Anti-psychotic Treatment

...  Weight Gain has been seen with patients taking Olanzapine; the increase of weight gain can result in other heart diseases such as hypertension and coronary heart disease.  QTc prolongation which occurs when there is an abnormally long delay between the electrical excitation and relaxation of the ...
Western Washington University Rowing Safety
Western Washington University Rowing Safety

... This section of the departmental Safety Information Book is intended to bring Western Washington University into compliance with Washington Administrative Code (WAC), Part 29662-500 Hazardous Drugs. The University seeks to protect its employees from avoidable harm at all times and places related to ...
Factors that may cause Bleeding with Enoxaparin
Factors that may cause Bleeding with Enoxaparin

... To determine the factors that may affect LMWH such as (weight, renal function, drugs and disease). and to check if there is any ...
Management of Drug Formulary
Management of Drug Formulary

... -most of the time utilizes 3-tier benefit design, but can more ...
Diagnostic Testing
Diagnostic Testing

... thinking they do not have the disease when they actually do  Clinical tests are adjusted to minimize the occurrence of false results ...
cardiac medications
cardiac medications

Absorption
Absorption

... • Potential for drug interactions is significant in the HIV infected patient. • May be an important cause of treatment failure. • Overlapping toxicities may increase the risk of adverse events. • Beneficial drug interactions are increasingly being used to enhance efficacy and reduce toxicity. ...
Nanotechnology in oral dosage forms. A. Sallam. Consultant. TQ
Nanotechnology in oral dosage forms. A. Sallam. Consultant. TQ

... when needed, adapt to address new challenges. Current published guidance may be applicable to nanoparticle therapeutics. Staff is working on addressing the need for guidance documents that address nano-related issues as well as the regulatory science to bring to bear this emerging technology . ...
WHY A FOCUS ON ADDICTIVE BEHAVIORS? Study of Drug Use
WHY A FOCUS ON ADDICTIVE BEHAVIORS? Study of Drug Use

... impotence; enlarged breasts in males has also been reported. - in females, failure to ovulate has been noted - if used during pregnancy may be associated with low birth weight, premature birth (but these women may also be smokers, drinkers) - pot as a “gateway” drug (Adolescents tend to use drugs in ...
request form - Exeter Laboratory
request form - Exeter Laboratory

... Location : ...
35 Generic Name Dicyclomine IUPAC Name 2
35 Generic Name Dicyclomine IUPAC Name 2

... Mechanism of Action Paracetamol is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, COX-1 and COX-2, enzymes involved in prostaglandin (PG) synthesis. Unlike NSAIDs, acetaminophen does not inhibit cyclooxygenase in peripheral tissues a ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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