• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Cardiac Tamponade Caused by Drug Interaction: A
Cardiac Tamponade Caused by Drug Interaction: A

... and warfarin results in the prolongation of the prothrombin time and introduces a risk of bleeding;4 – 6 these effects have been attributed in part to interference with the hepatic degradation of warfarin.7 Amiodarone is often prescribed for the treatment of supraventricular, junctional, and ventric ...
How to Help Your Low-Income Patients Get Prescription Drugs
How to Help Your Low-Income Patients Get Prescription Drugs

... 75 drug companies offer PAPs. Some compa- W-2 forms, tax returns, bank statements) to nies have a separate PAP for each drug or class verify the patient’s financial information. Eligibility. Eligibility requirements, such of drugs they make available. Companies do not necessarily make all of as inco ...
allergies to sulfonamide antibiotics and cross-reactivities
allergies to sulfonamide antibiotics and cross-reactivities

... Sulfonamides antibiotics are among the most frequent causes of adverse drug reactions. The hypersensitivity is known to be associated with arylamine moiety. Therefore no cross-reactivity would be expected between sulfonamide antibiotics (sulfonylarlamines) and other non-arylamine sulfonamides. While ...
Maintanence Treatment in Opioid Dependency
Maintanence Treatment in Opioid Dependency

... Rudolf Stohler - In my eyes, it is better to only provide substitution medication than nothing. See also articles by Schwartz et al. (5) However, best would be to provide long-term support for (re-)integration, ideally by the same person. Question 5. What do you recommend for patients who are no ...
February 2016 - PPR Travel Nursing
February 2016 - PPR Travel Nursing

... Despite the importance of teaching patients about the medications to take after discharge, studies suggest healthcare providers are not successfully preparing patients for the transition home. Between 30-70% of patients make a medication error in the immediate weeks following hospitalization,7-11 an ...
Radiation Pneumonitis - Abington & Jefferson, Better Together
Radiation Pneumonitis - Abington & Jefferson, Better Together

...  Delirium and use of rescue medications were performed using the Fisher exact test  Delirium free days, duration of study drug, and doses of rescue medications were performed using the MannWhitney test  Time to extubation and length of ICU stay were ...
Chapter 18 - Population genetics
Chapter 18 - Population genetics

... genotypes through time—individuals, populations, etc. • examine mutation, migration, breeding system, amongpopulation interactions, stochastic forces and selection on allele frequencies • developed to bridge gap between “genes” and “species ...
Day1-UVM-2ndvisit-Pombe
Day1-UVM-2ndvisit-Pombe

... than chlorine, chlorine dioxide, and potassium permanganate. And through catalysis, H2O2 can be converted into hydroxyl radicals (.OH) with reactivity second only to fluorine. • Grow the yeast and treat the control group with buffer (HBSS) and the treated group with buffer containing 0.5 mM H2O2 • I ...
CSIM – 3 things not to miss in Respirology 13:00
CSIM – 3 things not to miss in Respirology 13:00

... • Cough (dry in the beginning, then can develop traction bronchiectasis and productive cough) • Exercise intolerance Physical exam: • Depends on the ILD that is developing • Velcro crackles – usually basal (NSIP, UIP) ...
Chapter Three: Heredity and Environment
Chapter Three: Heredity and Environment

... If “late-onset,” (more prevalent as more people live to age 80) may be a combination of genes and environment It is easy to overestimate the role of genes in almost any condition known to be genetic. ...
GREEN METHODS TO DELIVER AMINOGLYCOSIDE DRUGS
GREEN METHODS TO DELIVER AMINOGLYCOSIDE DRUGS

... Figure 1. Common structures of aminoglycoside families Green chemistry in pharmaceutical development often concern the synthesis of the active ingredient, but green-chemistry techniques also can be applied to drug-product manufacturing, formulation development, and drug delivery.5 Drugs with the abi ...
Dear Family Member: This letter is to notify you that our family has
Dear Family Member: This letter is to notify you that our family has

... is a genetic (inherited) condition that is associated with an increased susceptibility to multiple types of cancer. The purpose of this letter is to familiarize you with hereditary cancer risk, and the steps that you can take to reduce the risk of cancer. Lynch syndrome is associated with an increas ...
Pharmacodynamics
Pharmacodynamics

... A term used whenever we compare the activity of two drugs producing the same effect Defined as the dose of one drug necessary to produce a specific response as compared to a second drug producing the same effect - Affinity: The ability of a drug to form a stable complex with the receptor ...
Document
Document

... My research on protein and proteome structure, function, and interaction is directed to understanding how genomes specify phenotype and behaviour; my goal is to use this information to improve human health and quality of life. Protein functions and interactions are mediated by atomic three dimension ...
Pharmacology PowerPoint
Pharmacology PowerPoint

... observe for increased symptoms ...
HIV Infection in Solid Organ Transplant Patients
HIV Infection in Solid Organ Transplant Patients

...  2) Frassetto L, Floren L, Barin B, et al. Changes in clearance, volume and bioavailability of immunosuppresants when given with HAART in HIV-1 infected liver and kidney transplant recipients. Biopharm Drug Dispos. 2013; not yet in print ...
Patent protection for new uses of known drugs
Patent protection for new uses of known drugs

... the principle that a new patient group can constitute a patentable invention. In particular, in a more recent decision (T1399/04) a patent was allowed for a combination therapy for treating chronic hepatitis C in previously untreated patients with a specific virus load and particular form of the vir ...
Nitrous Oxide/Oxygen
Nitrous Oxide/Oxygen

... • Blended mixture of 50% nitrous oxide and 50% oxygen • Also known as “laughing gas” • Produces sedation and analgesia • Colorless, odorless, heavier than air • Nonexplosive, nonflammable • Readily diffuses through membranes (rapid onset, short duration after inhalation is stopped) ...
Nitrous Oxide Guidlines
Nitrous Oxide Guidlines

... • Blended mixture of 50% nitrous oxide and 50% oxygen • Also known as “laughing gas” • Produces sedation and analgesia • Colorless, odorless, heavier than air • Nonexplosive, nonflammable • Readily diffuses through membranes (rapid onset, short duration after inhalation is stopped) ...
ISMP Medication Safety Alert
ISMP Medication Safety Alert

... vial, on carton labels to draw attention to it, or add auxiliary labels if the information is not available on the label. ...
drug physical symptoms look for dangers
drug physical symptoms look for dangers

... Long-term heavy use of amphetamines can lead to malnutrition, skin disorder, ulcers, and various diseases that come from vitamin deficiencies. Lack of sleep, weight loss, and depression also result from regular use. Frequent use of large amounts of amphetamines can produce brain damage that results ...
molecular physiology insight in overcoming
molecular physiology insight in overcoming

... Ethambutol (EMB) (inhibits an arabinosyl transferase and biosynthesis of arabinogalactan of cell wall) ...
Highlights of Products Added via Special Authorization (SA
Highlights of Products Added via Special Authorization (SA

PDR Network (Health Care Notification Network)
PDR Network (Health Care Notification Network)

... The PDR is the leading provider of print and online pharmaceutical information to physicians, and the HCNN is the only FDA-compliant network that electronically delivers specialtyspecific product safety notices. The prompt delivery of important medication-related and medical device–related patient s ...
Genetic Testing
Genetic Testing

< 1 ... 1023 1024 1025 1026 1027 1028 1029 1030 1031 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report