งานนำเสนอ PowerPoint
... -OH with sulphate to give sulphates -NH2, -CONH2, amino acids, sulpha drugs with acetyl- to give acetylated derivatives -halo, -nitrate, epoxide, sulphate with glutathione to give glutathione conjugates all tend to be less lipid soluble and therefore better ...
... -OH with sulphate to give sulphates -NH2, -CONH2, amino acids, sulpha drugs with acetyl- to give acetylated derivatives -halo, -nitrate, epoxide, sulphate with glutathione to give glutathione conjugates all tend to be less lipid soluble and therefore better ...
Intrahepatic biliary tract disease - Ipswich-Year2-Med-PBL-Gp-2
... o Non-ceruloplasmin-bound copper spills into circulation haemolysis and other pathological changes Morphology: o Hepatic changes range from minor to massive (steatosis, vacuolated nuclei, focal hepatocyte necrosis, acute hepatitis are all possible) o Chronic hepatitis: exhibits moderate – severe i ...
... o Non-ceruloplasmin-bound copper spills into circulation haemolysis and other pathological changes Morphology: o Hepatic changes range from minor to massive (steatosis, vacuolated nuclei, focal hepatocyte necrosis, acute hepatitis are all possible) o Chronic hepatitis: exhibits moderate – severe i ...
Basic Toxicology Reference
... A Local effect refers to an adverse health effect that takes place at the point or area of contact. The site may be skin, mucous membranes, the respiratory tract, gastrointestinal system, eyes, etc. Absorption does not necessarily occur. Examples: strong acids or alkalis. Systemic effect refers to a ...
... A Local effect refers to an adverse health effect that takes place at the point or area of contact. The site may be skin, mucous membranes, the respiratory tract, gastrointestinal system, eyes, etc. Absorption does not necessarily occur. Examples: strong acids or alkalis. Systemic effect refers to a ...
Plants That Are Poisonous To Alpacas
... during winter or early spring when poor forage availability forces animals to consume large quantities. Saponins present in the foliage are responsible for the poisoning, and can cause illness, death, or abortion in livestock. However, toxicity apparently varies with phenological stage and substrate ...
... during winter or early spring when poor forage availability forces animals to consume large quantities. Saponins present in the foliage are responsible for the poisoning, and can cause illness, death, or abortion in livestock. However, toxicity apparently varies with phenological stage and substrate ...
Introduction
... Bacillus anthracis, which forms endospores Spreads to humans from infected animals Enters the human body through: • Inhalation; causing breathing problems that usually ...
... Bacillus anthracis, which forms endospores Spreads to humans from infected animals Enters the human body through: • Inhalation; causing breathing problems that usually ...
human poisoning after ingestion of puffer fish caught from
... her fingers associated with blurred vision, head heaviness, nausea and one episode of vomiting. Ten minutes later, she lost her ability to hold her head up and had developed weakness of her upper and lower extremities. This was accompanied by mild abdominal distention and urinary urgency. The patien ...
... her fingers associated with blurred vision, head heaviness, nausea and one episode of vomiting. Ten minutes later, she lost her ability to hold her head up and had developed weakness of her upper and lower extremities. This was accompanied by mild abdominal distention and urinary urgency. The patien ...
Toxicology (Introduction) - Home
... It results from repeated exposure for several weeks or months. This is a common human exposure pattern for some pharmaceuticals and environmental agents. Examples are: -Ingestion of coumadin tablets (blood thinners) for several weeks as a treatment for venous thrombosis can cause internal bleeding. ...
... It results from repeated exposure for several weeks or months. This is a common human exposure pattern for some pharmaceuticals and environmental agents. Examples are: -Ingestion of coumadin tablets (blood thinners) for several weeks as a treatment for venous thrombosis can cause internal bleeding. ...
TCAs
... heart rate). As the degree of Na+ channel block increases with use, the QRS width will increase with increasing heart rates. ...
... heart rate). As the degree of Na+ channel block increases with use, the QRS width will increase with increasing heart rates. ...
HEAVY METALS2
... leukocytes, and plasma proteins. • It is cleared from the intravascular compartment within 24 hours and concentrates in the liver, kidneys, spleen, lungs, and gastrointestinal tract. • Arsenic crosses the placenta and can also accumulate in the fetus. • Its affinity for sulfhydryl groups in keratin ...
... leukocytes, and plasma proteins. • It is cleared from the intravascular compartment within 24 hours and concentrates in the liver, kidneys, spleen, lungs, and gastrointestinal tract. • Arsenic crosses the placenta and can also accumulate in the fetus. • Its affinity for sulfhydryl groups in keratin ...
Asymptomatic Elevation of Transaminases
... SGPT, along with PCR for HBV-DNA and HCV-RNA. In this study 51.5 % of these patients had chronic hepatitis, 32.7 % patients had non specific changes and 15.8 % patients had NASH. Thus, using more sophisticated techniques a large proportion of patients with elevated SGPT levels are found to have chro ...
... SGPT, along with PCR for HBV-DNA and HCV-RNA. In this study 51.5 % of these patients had chronic hepatitis, 32.7 % patients had non specific changes and 15.8 % patients had NASH. Thus, using more sophisticated techniques a large proportion of patients with elevated SGPT levels are found to have chro ...
ICD-9 272.7 Chemically induced lipidosis. 293.83 Mood Disorder
... 713.6 Arthropathy associated with hypersensitivity reaction Code first underlying disease, as: Henoch (-Schönlein) purpura (287.0); serum sickness (999.5) Excludes: allergic arthritis NOS (716.2) 713.7 Other general diseases with articular involvement Code first underlying disease, as: amyloidosis ( ...
... 713.6 Arthropathy associated with hypersensitivity reaction Code first underlying disease, as: Henoch (-Schönlein) purpura (287.0); serum sickness (999.5) Excludes: allergic arthritis NOS (716.2) 713.7 Other general diseases with articular involvement Code first underlying disease, as: amyloidosis ( ...
There are two types of food poisoning
... • the organisms originating in the gut of cattle and poultry. • The most common source of the infection is meat, such as chicken, or contaminated milk products. • The leading cause of enteritis worldwide • Very low infective does required to cause infection • The incubation period is 2-5 days. • Col ...
... • the organisms originating in the gut of cattle and poultry. • The most common source of the infection is meat, such as chicken, or contaminated milk products. • The leading cause of enteritis worldwide • Very low infective does required to cause infection • The incubation period is 2-5 days. • Col ...
Food Poisoning - General Information
... pre-prepared salads and soft serve icecream. The initial symptoms are flu-like, with general aches and fever. Meningitis and septicaemia (blood poisoning) can develop. Symptoms develop approximately three weeks after eating contaminated food, however in some cases it may take several months. • Salmo ...
... pre-prepared salads and soft serve icecream. The initial symptoms are flu-like, with general aches and fever. Meningitis and septicaemia (blood poisoning) can develop. Symptoms develop approximately three weeks after eating contaminated food, however in some cases it may take several months. • Salmo ...
Types of Pesticides
... have become one of the most commonly used insecticide classes in recent years, with compounds registered on many major crops for foliar application and/or seed treatment. Active ingredients include imidicloprid, clothiandin, thiamethoxam, acetamiprid, thiacloprid, and dinotefuran. They are are sold ...
... have become one of the most commonly used insecticide classes in recent years, with compounds registered on many major crops for foliar application and/or seed treatment. Active ingredients include imidicloprid, clothiandin, thiamethoxam, acetamiprid, thiacloprid, and dinotefuran. They are are sold ...
S01 Toxicology Introduction
... Toxicokinetics is the quantitation of the time course of toxicants in the body during the processes of absorption, distribution, biotransformation, and excretion or clearance of toxicants In other words, toxicokinetics is a reflection of how the body handles toxicants as indicated by the plasma conc ...
... Toxicokinetics is the quantitation of the time course of toxicants in the body during the processes of absorption, distribution, biotransformation, and excretion or clearance of toxicants In other words, toxicokinetics is a reflection of how the body handles toxicants as indicated by the plasma conc ...
Pharmacological Basis of Poisoning
... Gastric Lavage (GL) May be useful for drugs that are not effectively absorbed by activated charcoal. Typically it is given via a wide bore OG or NG tube. The lavage fluid is usually around five litres of warmed saline. Of note it is associated with an increased risk of ICU admission and aspiration. ...
... Gastric Lavage (GL) May be useful for drugs that are not effectively absorbed by activated charcoal. Typically it is given via a wide bore OG or NG tube. The lavage fluid is usually around five litres of warmed saline. Of note it is associated with an increased risk of ICU admission and aspiration. ...
Hepatotoxicity file
... b) Mitochondrial dysfunction: Responsible for ATP and Ca++ regulation CCl4, cocaine, dichlorethylene, ethionine, hydrazine, and phosphorus. ...
... b) Mitochondrial dysfunction: Responsible for ATP and Ca++ regulation CCl4, cocaine, dichlorethylene, ethionine, hydrazine, and phosphorus. ...
Ciguatera Fish Poisoning
... Rest remains unknown however, other studies suggest the following: • Can lead to sensitization to ciguatoxins in CFP patients • the poison inhibits the action of cholinesterase ...
... Rest remains unknown however, other studies suggest the following: • Can lead to sensitization to ciguatoxins in CFP patients • the poison inhibits the action of cholinesterase ...
Toxicopathological and biochemical effects of Carbon Tetrachloride
... main functions of the organism. It is particularly susceptible to chemically induced injury due to its extensive metabolic capacity and cellular heterogeneity (1). Carbon tetrachloride (CCl4) has long been known as a model toxicant and has been the focus of many in vitro and in vivo toxicological st ...
... main functions of the organism. It is particularly susceptible to chemically induced injury due to its extensive metabolic capacity and cellular heterogeneity (1). Carbon tetrachloride (CCl4) has long been known as a model toxicant and has been the focus of many in vitro and in vivo toxicological st ...
Insecticides: Cholinesterase Inhibitors
... • Pyrethroids are rapidly metabolized through both type I and type II reaction (hydrolysis and oxidation as well as conjugation) ...
... • Pyrethroids are rapidly metabolized through both type I and type II reaction (hydrolysis and oxidation as well as conjugation) ...
Poisonings from ingestion of chlorate
... Objective Chlorates are strong oxidizers and used as ingredients in matches, explosives and dyestuffs as well as herbicides. Although commercial use of chlorate-containing weed killers is banned within the EU, they can still be purchased by private consumers as “stone cleaners” in large quantities, ...
... Objective Chlorates are strong oxidizers and used as ingredients in matches, explosives and dyestuffs as well as herbicides. Although commercial use of chlorate-containing weed killers is banned within the EU, they can still be purchased by private consumers as “stone cleaners” in large quantities, ...
UNITED
... Typically, the effects vary greatly in severity and/or causative dose level from one species to another; for example, thalidomide manifests skeletal abnormalities with a range of doses across species of at least 3 orders of magnitude. It is well known that there is no orderly systematic way of predi ...
... Typically, the effects vary greatly in severity and/or causative dose level from one species to another; for example, thalidomide manifests skeletal abnormalities with a range of doses across species of at least 3 orders of magnitude. It is well known that there is no orderly systematic way of predi ...
Bad Bug Book - Henry The Hand
... This handbook provides basic facts regarding foodborne pathogenic microorganisms and natural toxins. It brings together in one place information from the Food & Drug Administration, the Centers for Disease Control & Prevention, the USDA Food Safety Inspection Service, and the National Institutes of ...
... This handbook provides basic facts regarding foodborne pathogenic microorganisms and natural toxins. It brings together in one place information from the Food & Drug Administration, the Centers for Disease Control & Prevention, the USDA Food Safety Inspection Service, and the National Institutes of ...
Problem of the Lower GI Tract Diverticulosis & Diverticulitis
... Cardiac- Right-sided CHF. Liver is ...
... Cardiac- Right-sided CHF. Liver is ...
Amanita phalloides
Amanita phalloides /æməˈnaɪtə fəˈlɔɪdiːz/, commonly known as the death cap, is a deadly poisonous basidiomycete fungus, one of many in the genus Amanita. Widely distributed across Europe, A. phalloides forms ectomycorrhizas with various broadleaved trees. In some cases, the death cap has been introduced to new regions with the cultivation of non-native species of oak, chestnut, and pine. The large fruiting bodies (mushrooms) appear in summer and autumn; the caps are generally greenish in color, with a white stipe and gills.These toxic mushrooms resemble several edible species (most notably caesar's mushroom and the straw mushroom) commonly consumed by humans, increasing the risk of accidental poisoning. A. phalloides is one of the most poisonous of all known toadstools. It has been involved in the majority of human deaths from mushroom poisoning, possibly including the deaths of Roman Emperor Claudius in AD 54 and Holy Roman Emperor Charles VI in 1740. It has been the subject of much research, and many of its biologically active agents have been isolated. The principal toxic constituent is α-amanitin, which damages the liver and kidneys, often fatally.