Polymer in Reactint Orange X96
... will only occur during accidental release. Inhalational and dermal exposure can occur during repackaging operations but will be minimised as local exhaust ventilation will be used during this operation. The main occupational exposure will occur during production of polyurethane foam for which the po ...
... will only occur during accidental release. Inhalational and dermal exposure can occur during repackaging operations but will be minimised as local exhaust ventilation will be used during this operation. The main occupational exposure will occur during production of polyurethane foam for which the po ...
9.4 Overall Assessment of Toxicological Data
... the negative controls gave background chromosomal aberration frequencies with the range expected for V79 cells and the positive control chemicals gave the expected increases in the first of 2 experiments a statistically significant increase in the percentage of cells withstructural chromosomal aberr ...
... the negative controls gave background chromosomal aberration frequencies with the range expected for V79 cells and the positive control chemicals gave the expected increases in the first of 2 experiments a statistically significant increase in the percentage of cells withstructural chromosomal aberr ...
sample Report - ZRT Laboratory
... narrow, with tolerable upper intake levels recommended at about 400 micrograms/day. Higher levels (up to 800micrograms) have been used in cancer patients without significant side effects. Chronic high selenium is associated with symptoms such as hair and nail loss and brittleness. Food is the major ...
... narrow, with tolerable upper intake levels recommended at about 400 micrograms/day. Higher levels (up to 800micrograms) have been used in cancer patients without significant side effects. Chronic high selenium is associated with symptoms such as hair and nail loss and brittleness. Food is the major ...
Fluoride inhibition of superoxide dismutase (SOD)
... cycles.2 Organelles such as mitochondria, chloroplasts, microsomes, and nuclei have been shown also to generate this radical.3,4 Much of the toxicity of O2–˙ is due to the fact that it can act as either a univalent oxidant or a reductant. Superoxide free radical and toxic products of singlet oxygen ...
... cycles.2 Organelles such as mitochondria, chloroplasts, microsomes, and nuclei have been shown also to generate this radical.3,4 Much of the toxicity of O2–˙ is due to the fact that it can act as either a univalent oxidant or a reductant. Superoxide free radical and toxic products of singlet oxygen ...
embryotoxicity of diclofenac on danio rerio: mortality, morphological
... (NSAID) taken to reduce inflammation and as an analgesic reducing pain in conditions such as arthritis or acute injury. It can also be used to reduce menstrual pain, dysmenorrhea. The name is derived from its chemical name: 2-(2,6-dichloranilino) phenylacetic acid. The primary mechanism responsible ...
... (NSAID) taken to reduce inflammation and as an analgesic reducing pain in conditions such as arthritis or acute injury. It can also be used to reduce menstrual pain, dysmenorrhea. The name is derived from its chemical name: 2-(2,6-dichloranilino) phenylacetic acid. The primary mechanism responsible ...
Clandestine Amphetamine-Derived Drug Laboratories
... order to prevent exposures. In the United States, over 20 states have established cleanup guidelines with remediation levels set according to “what are believed to be conservative to account for scientific uncertainty while at the same time establishing a standard/ guideline that sites remediation c ...
... order to prevent exposures. In the United States, over 20 states have established cleanup guidelines with remediation levels set according to “what are believed to be conservative to account for scientific uncertainty while at the same time establishing a standard/ guideline that sites remediation c ...
The Fate and Effect of Glyphosate on Amphibians
... Unlikely for glyphosate to leach into groundwater due to surfactant Contamination can occur by drift/overspray and direct application Actual concentrations observed are dependent on several factors including application rate, interception by target vegetation, water depth, amount of suspended solids ...
... Unlikely for glyphosate to leach into groundwater due to surfactant Contamination can occur by drift/overspray and direct application Actual concentrations observed are dependent on several factors including application rate, interception by target vegetation, water depth, amount of suspended solids ...
Document
... NICOTINE •Poisonous chemicals in cigarettes •Highly addictive •Hardens the blood vessels – blood cannot flow through them easily – causes high blood pressure •Causes lung cancer ...
... NICOTINE •Poisonous chemicals in cigarettes •Highly addictive •Hardens the blood vessels – blood cannot flow through them easily – causes high blood pressure •Causes lung cancer ...
Role and deficiency symptoms of Nitrogen in grape
... Role and deficiency symptoms of Nitrogen in grape Role of Nitrogen in grapevine Vines use nitrogen to build many compounds essential for growth and development. Among these are amino acids, nucleic acids, proteins (including all enzymes), and pigments, including the green chlorophyll of leaves and ...
... Role and deficiency symptoms of Nitrogen in grape Role of Nitrogen in grapevine Vines use nitrogen to build many compounds essential for growth and development. Among these are amino acids, nucleic acids, proteins (including all enzymes), and pigments, including the green chlorophyll of leaves and ...
What is DDT? - National Pesticide Information Center
... small and practically non-toxic when the value is large. However, the LD50/LC50 does not reflect any effects from long-term exposure (i.e., cancer, birth defects or reproductive toxicity) which may occur at doses below those used in short-term studies. ...
... small and practically non-toxic when the value is large. However, the LD50/LC50 does not reflect any effects from long-term exposure (i.e., cancer, birth defects or reproductive toxicity) which may occur at doses below those used in short-term studies. ...
and poly-fluoroalkyl substances (PFAS)
... The existing limited studies on PFHxS suggest that this chemical can cause effects in laboratory test animals similar to the effects caused by PFOS. However, based on available studies, PFHxS appears to be less potent in animal studies than PFOS. Much of the research on humans has been done with peo ...
... The existing limited studies on PFHxS suggest that this chemical can cause effects in laboratory test animals similar to the effects caused by PFOS. However, based on available studies, PFHxS appears to be less potent in animal studies than PFOS. Much of the research on humans has been done with peo ...
Zebrafish models for assessing developmental and reproductive
... hatching and a variety of morphological abnormalities such as altered body size, eye size, head size and formation, body curvature, tail formation, pigmentation, swim bladder inflation, edema, and malformation in the pericardial sac and yolk sac (Fig. 3) (Gustafson et al., 2012; Weigt et al., 2011). ...
... hatching and a variety of morphological abnormalities such as altered body size, eye size, head size and formation, body curvature, tail formation, pigmentation, swim bladder inflation, edema, and malformation in the pericardial sac and yolk sac (Fig. 3) (Gustafson et al., 2012; Weigt et al., 2011). ...
DIETARY ALPHA-TOCOPHEROL PREVENTS PHENOL INDUCED OXIDATIVE STRESS IN BRAIN HETEROPNEUSTES FOSSILIS
... structural integrity, decreased membrane fluidity and inactivation of several membrane-bound enzymes38. The observation is in agreement with the view that the enhancement of peroxidation of an essential functional membrane lipid could damage the biological membranes. Besides this the results present ...
... structural integrity, decreased membrane fluidity and inactivation of several membrane-bound enzymes38. The observation is in agreement with the view that the enhancement of peroxidation of an essential functional membrane lipid could damage the biological membranes. Besides this the results present ...
Volume 83 Tobacco Smoke and Involuntary Smoking
... carcinogenicity. Both kinds of condensates produced a spectrum of benign and malignant skin tumours in mice following topical application, and the sidestream condensate exhibited higher carcinogenic activity. Sidestream smoke condensate was shown to produce a dose-dependent increase in lung tumours ...
... carcinogenicity. Both kinds of condensates produced a spectrum of benign and malignant skin tumours in mice following topical application, and the sidestream condensate exhibited higher carcinogenic activity. Sidestream smoke condensate was shown to produce a dose-dependent increase in lung tumours ...
1. Objectives of the Presentation 2. General Key Points: 3. Key
... oxygen, tissue hypoxia develops. As neurologic tissues are sensitive to low oxygen tension, neurologic clinical signs are commonly encountered. Treatment of nitrate poisoning involves conversion of methemoglobin back to hemoglobin. This is accomplished with methylene blue. Methylene blue is administ ...
... oxygen, tissue hypoxia develops. As neurologic tissues are sensitive to low oxygen tension, neurologic clinical signs are commonly encountered. Treatment of nitrate poisoning involves conversion of methemoglobin back to hemoglobin. This is accomplished with methylene blue. Methylene blue is administ ...
BIOCHEMICAL EFFECTS OF ENDOSULFAN IN LIVER OF ALBINO RATS Research Article
... Endosulfan a nonsystemic contact organochlorine insecticide and acaricide is used extensively for pest control. There is some indication that endosulfan can have adverse effect on the immune system at low level of exposure2. In India about 1000 metric tons of endosulfan and its formulations have bee ...
... Endosulfan a nonsystemic contact organochlorine insecticide and acaricide is used extensively for pest control. There is some indication that endosulfan can have adverse effect on the immune system at low level of exposure2. In India about 1000 metric tons of endosulfan and its formulations have bee ...
Comparison of Toxicity for Methyl Iodide and Methyl Bromide
... Methyl iodide causes developmental toxicity at doses four times lower than methyl bromide. Methyl iodide causes “fetal losses” (miscarriages) by interfering with the thyroid hormone levels during pregnancy. Methyl bromide causes birth defects and is on the California Prop 65 list of developmental to ...
... Methyl iodide causes developmental toxicity at doses four times lower than methyl bromide. Methyl iodide causes “fetal losses” (miscarriages) by interfering with the thyroid hormone levels during pregnancy. Methyl bromide causes birth defects and is on the California Prop 65 list of developmental to ...
Aloe Vera and Digestion, Irritable Bowel and Arthritis
... Although known specifically for external application to the skin, Aloe Juice is now widely used to help a variety of conditions of the digestive tract. It is important at this stage to stress that, as with any medical condition, a pain in the abdomen should be referred to a medical practitioner in t ...
... Although known specifically for external application to the skin, Aloe Juice is now widely used to help a variety of conditions of the digestive tract. It is important at this stage to stress that, as with any medical condition, a pain in the abdomen should be referred to a medical practitioner in t ...
N-(n-butyl) thiophosphoric triamide (NBPT)—secondary
... females is 17 mg/kg bw/d based on effects seen in the uterus. NBPT caused weight changes in reproductive organs with histopathological findings in both males and females, and abnormalities in sperm evaluations. The NOAEL in males is 21 mg/kg bw/d based on decreased sperm motility with epididymal les ...
... females is 17 mg/kg bw/d based on effects seen in the uterus. NBPT caused weight changes in reproductive organs with histopathological findings in both males and females, and abnormalities in sperm evaluations. The NOAEL in males is 21 mg/kg bw/d based on decreased sperm motility with epididymal les ...
Calcium carbide - Santa Cruz Biotechnology
... ! There is some evidence to suggest that the material can cause respiratory irritation in some persons. The body's response to such irritation can cause further lung damage. ! No symptoms occur from the presence of 2. 5% acetylene in air (the LEL); at 10–20% a reversible narcosis can occur. ! The on ...
... ! There is some evidence to suggest that the material can cause respiratory irritation in some persons. The body's response to such irritation can cause further lung damage. ! No symptoms occur from the presence of 2. 5% acetylene in air (the LEL); at 10–20% a reversible narcosis can occur. ! The on ...
Health Effects of Fine Particulate Air Pollution: Lines that Connect
... tunnel were found to exert inflammatory effects in the lung,12 and the non-PM fraction was more potent per unit of mass and caused the majority of the response. Although CAPs have enhanced atherosclerotic changes in vessels of genetically susceptible mice,13 recent research has shown that the non-PM ...
... tunnel were found to exert inflammatory effects in the lung,12 and the non-PM fraction was more potent per unit of mass and caused the majority of the response. Although CAPs have enhanced atherosclerotic changes in vessels of genetically susceptible mice,13 recent research has shown that the non-PM ...
Eighty-first meeting. Residues of veterinary drugs
... pesticide residues can be used. The key differences between veterinary drugs and pesticides relate to microbiological effects and to specific exposure scenarios. Regarding pharmacological effects – i.e. interaction with molecular targets (e.g. receptors) – it was noted that this is not unique to vet ...
... pesticide residues can be used. The key differences between veterinary drugs and pesticides relate to microbiological effects and to specific exposure scenarios. Regarding pharmacological effects – i.e. interaction with molecular targets (e.g. receptors) – it was noted that this is not unique to vet ...
Chapter 1
... on the runners speed. At a low pace, the increased oxygen demand, caused by contracting muscles is compensated by an increasing heart-rate, cardiac output and breathing rate. This results in an increased oxygen uptake and the body will reach a new steady state where the stress of running is (almost) ...
... on the runners speed. At a low pace, the increased oxygen demand, caused by contracting muscles is compensated by an increasing heart-rate, cardiac output and breathing rate. This results in an increased oxygen uptake and the body will reach a new steady state where the stress of running is (almost) ...
Effect of different cyanobacterial biomasses and their fractions with
... Fig. 2. Cumulative mortality of carp embryos after 120 h exposure to four different samples of cyanobacterial water blooms and its fractions. Significant differences from the control are labeled by asterisks (* p ≤ 0.05; ** p ≤ 0.01). ...
... Fig. 2. Cumulative mortality of carp embryos after 120 h exposure to four different samples of cyanobacterial water blooms and its fractions. Significant differences from the control are labeled by asterisks (* p ≤ 0.05; ** p ≤ 0.01). ...
Organophosphate poisoning
Organophosphate poisoning results from exposure to organophosphates (OPs), which cause the inhibition of acetylcholinesterase (AChE), leading to the accumulation of acetylcholine (ACh) in the body. Organophosphate poisoning most commonly results from exposure to insecticides or nerve agents. OPs are one of the most common causes of poisoning worldwide, and are frequently intentionally used in suicides in agrarian areas. There are around 1 million OP poisonings per year with several hundred thousand resulting in fatalities annually.Organophosphates inhibit AChE, causing OP poisoning by phosphorylating the serine hydroxyl residue on AChE, which inactivates AChE. AChE is critical for nerve function, so the irreversible blockage of this enzyme, which causes acetylcholine accumulation, results in muscle overstimulation. This causes disturbances across the cholinergic synapses and can only be reactivated very slowly, if at all. Paraoxonase (PON1) is a key enzyme involved in OP pesticides and has been found to be critical in determining an organism's sensitivity to OP exposure.