Large-Scale High-Resolution Orthology Using Gene Trees
... Genes are homologous if and only if they derive from the same ancestral gene • Sufficient sequence similarity proofs homology • Very dissimilar sequences: PSI blast, HMM searches ...
... Genes are homologous if and only if they derive from the same ancestral gene • Sufficient sequence similarity proofs homology • Very dissimilar sequences: PSI blast, HMM searches ...
Horizontal and Vertical Gene Transfer
... Accumulation of genome sequence information has identified candidates of horizontally transferred genes among and between species. Most knowledge about horizontal gene transfer has been obtained from experience with prokaryocytes. Analysis of the genes of E.coli and Salmonella shows that 17% of the ...
... Accumulation of genome sequence information has identified candidates of horizontally transferred genes among and between species. Most knowledge about horizontal gene transfer has been obtained from experience with prokaryocytes. Analysis of the genes of E.coli and Salmonella shows that 17% of the ...
Identifying essential genes in M. tuberculosis by random
... • Of 4250 genes, 1005 pairs overlap (mostly by exactly 4 bp). • The overlapping regions contain 547 insertion sites. • Omit TA sites in overlapping regions unless in the proximal portion of both genes. • The algebra gets a bit more complicated. ...
... • Of 4250 genes, 1005 pairs overlap (mostly by exactly 4 bp). • The overlapping regions contain 547 insertion sites. • Omit TA sites in overlapping regions unless in the proximal portion of both genes. • The algebra gets a bit more complicated. ...
Response to Nelson-Sathi et al. (Nature 517, 77-80
... Figure 2: Consistency of gene family ancestral gain estimations on the “import” gene set. Along the archaeal reference tree provided by Nelson-Sathi et al. (2015) [NS], both Parsimony (green) and Maximum Likelihood (blue) inferences of ancestral gains were computed with Count (Csurs and Miklos, 2006 ...
... Figure 2: Consistency of gene family ancestral gain estimations on the “import” gene set. Along the archaeal reference tree provided by Nelson-Sathi et al. (2015) [NS], both Parsimony (green) and Maximum Likelihood (blue) inferences of ancestral gains were computed with Count (Csurs and Miklos, 2006 ...
Dr. McKay`s lecture
... Contains ~100 million bp on 6 chromosomes Predicted to contain ~20, 000 genes. ~ 55% of these genes are similar to genes from other organisms. • ~ 20% associated with mutationally defined genetic loci ...
... Contains ~100 million bp on 6 chromosomes Predicted to contain ~20, 000 genes. ~ 55% of these genes are similar to genes from other organisms. • ~ 20% associated with mutationally defined genetic loci ...
Sex-Linked Inheritance Student Notes • Sex linked inheritance
... The ____________ carries little genetic information, mainly those that contribute to ________________ characteristics. (About _____________ genes total.) ...
... The ____________ carries little genetic information, mainly those that contribute to ________________ characteristics. (About _____________ genes total.) ...
GOBASE—a database of organelle and bacterial
... of complex genes (Figure 1a) and neighbouring genes on the chromosome (Figure 1b). This also allows for a more sophisticated representation of trans-spliced genes than has previously been possible. Information from the Gene Ontology project (9) has also been integrated into the GOBASE database. Ever ...
... of complex genes (Figure 1a) and neighbouring genes on the chromosome (Figure 1b). This also allows for a more sophisticated representation of trans-spliced genes than has previously been possible. Information from the Gene Ontology project (9) has also been integrated into the GOBASE database. Ever ...
rabbit - Ensembl Mobile Site
... although noncoding genes and pseudogenes may also annotated. Every gene model produced by the Ensembl gene annotation pipeline is supported by biological sequence evidence (see the “Supporting evidence” link on the left-hand menu of a Gene page or Transcript page); ab initio models are not included ...
... although noncoding genes and pseudogenes may also annotated. Every gene model produced by the Ensembl gene annotation pipeline is supported by biological sequence evidence (see the “Supporting evidence” link on the left-hand menu of a Gene page or Transcript page); ab initio models are not included ...
Double Helix With a Twist
... Still, there could be long-term implications. Mr. Gibbons said having fewer genes was good news. ''We get to drugs and profits faster than if we have to sort through 100,000 genes,'' he said. But others say it means more limited prospects for genomics companies and less of a cornucopia for drug comp ...
... Still, there could be long-term implications. Mr. Gibbons said having fewer genes was good news. ''We get to drugs and profits faster than if we have to sort through 100,000 genes,'' he said. But others say it means more limited prospects for genomics companies and less of a cornucopia for drug comp ...
Fulltext PDF
... vindicated the views expressed by geneticists working with higher organisms, that a gene may after all be divisible into subunits. Thus, a gene may include more than one functional unit or cistron (leading to the 'one gene one enzyme' hypothesis being replaced by the 'one cistron one polypeptide' co ...
... vindicated the views expressed by geneticists working with higher organisms, that a gene may after all be divisible into subunits. Thus, a gene may include more than one functional unit or cistron (leading to the 'one gene one enzyme' hypothesis being replaced by the 'one cistron one polypeptide' co ...
Mendelian Genetics
... X and Y are not homologous Y chromosomes contains genes that determine maleness i. Y (15 genes) is 1/3 the size of X (2500 genes) X codes for additional non-sexual characteristics A gene found only on the X (and not Y) is said to be sex-linked i. Inheritance of sex-linked recessive genes cannot be m ...
... X and Y are not homologous Y chromosomes contains genes that determine maleness i. Y (15 genes) is 1/3 the size of X (2500 genes) X codes for additional non-sexual characteristics A gene found only on the X (and not Y) is said to be sex-linked i. Inheritance of sex-linked recessive genes cannot be m ...
Overview of Genome Browsers
... Click browser to go to Genome Browser image location (next slide) Click details to see the alignment to genomic sequence (2nd slide) ...
... Click browser to go to Genome Browser image location (next slide) Click details to see the alignment to genomic sequence (2nd slide) ...
Reverse Genetics- Gene Knockouts
... Reverse genetics is where one has already cloned or determined the sequence of a gene and wishes to determine the function of that gene. It is a common approach with the availability of genome sequences. Although we have the genomic sequence and can make a good approximation of what proteins are enc ...
... Reverse genetics is where one has already cloned or determined the sequence of a gene and wishes to determine the function of that gene. It is a common approach with the availability of genome sequences. Although we have the genomic sequence and can make a good approximation of what proteins are enc ...
manual - GSA-SNP
... values, the user should uncheck the “Take -log” option. But, make sure that large values in the input data should represent high associations. Some data types have their own parameters: Data type ...
... values, the user should uncheck the “Take -log” option. But, make sure that large values in the input data should represent high associations. Some data types have their own parameters: Data type ...
Human Genome Research
... The issues of scope and usefulness raise the question of at what stage in the process it is most appropriate to patent. There is near universal agreement that raw sequence data should not be patentable per se. This position was reiterated by the recent joint statement3 by President Clinton and Prime ...
... The issues of scope and usefulness raise the question of at what stage in the process it is most appropriate to patent. There is near universal agreement that raw sequence data should not be patentable per se. This position was reiterated by the recent joint statement3 by President Clinton and Prime ...
Genes Reading Group, Minutes 4. (Dec 4)
... This paper and some of the earlier readings suggests a list of Gene concepts (Mendelian) = stretch of chromosome associated with a phenotypic difference (Evolutionary) = any stretch of DNA that segregates and recombines with frequency, not concept of genotype-phenotype map unit of heredity = unit ...
... This paper and some of the earlier readings suggests a list of Gene concepts (Mendelian) = stretch of chromosome associated with a phenotypic difference (Evolutionary) = any stretch of DNA that segregates and recombines with frequency, not concept of genotype-phenotype map unit of heredity = unit ...
gene families
... 9. Anopheles has three chromosomes, and remarkably, when they mapped where all these 1:1 fly orthologs were on the chromosome arms, it turns out that despite a lot of gene movement between arms, the basic identity of the five chromosome arms can still be recognized (unfortunately, except for the X, ...
... 9. Anopheles has three chromosomes, and remarkably, when they mapped where all these 1:1 fly orthologs were on the chromosome arms, it turns out that despite a lot of gene movement between arms, the basic identity of the five chromosome arms can still be recognized (unfortunately, except for the X, ...
How to Composite Microarray Data Files
... that gene in relation to the wild type e. All positive ratios of the gene such as ORF05444 (a ferrous iron transport protein) indicating up regulation in the mutant versus the wild type. 2. It is possible that some ratios will be positive in some hybs and negative in others. a. This is part of the i ...
... that gene in relation to the wild type e. All positive ratios of the gene such as ORF05444 (a ferrous iron transport protein) indicating up regulation in the mutant versus the wild type. 2. It is possible that some ratios will be positive in some hybs and negative in others. a. This is part of the i ...
ppt - University of California, Berkeley
... If text seems to contain evidence for rRNA transcription (GO:0009303) nucleolus (GO:0005737) and extracellular (GO:0005576), then extracellular is suspicious. The algorithm identifies the “suspicious” cases. ...
... If text seems to contain evidence for rRNA transcription (GO:0009303) nucleolus (GO:0005737) and extracellular (GO:0005576), then extracellular is suspicious. The algorithm identifies the “suspicious” cases. ...
Copy-number variation
Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.