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The HAT2 Homeodomain-Like Transcription Factor Family
The HAT2 Homeodomain-Like Transcription Factor Family

... What is a HAT2 Homeodomain Transcription Factor? • Type of transcription factor that is only found in plants • Has been studied in sunflowers, where it is expressed primarily in the leaves • When Hahb-4 (sunflower homeobox-leucine zipper protein) was introduced into Arabidopsis, plants were more to ...
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... when taking the approach common for GWAS of identifying genes related to interesting SNPs. For a GWAS, usually both the SNP coordinates and genes that contain those SNPs are provided by the manufacturer of the genotyping platform. However, how these coordinates and genes are identified is often uncl ...
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CorrelateTalk
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... mutation frequencies of 6 X 10-3 to 1.5 x 10-3, equivalent to obtaining a mutation in a single gene of choice in one out of every 175 to 655 gametes screened. • Because it is a point mutagen, ENU can induce many different types of alleles. Loss of function mutations, viable hypomorphs of lethal comp ...
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B-Cell Gene Rearrangement

... challenge on the basis of histopathology alone. During normal B-cell maturation, the immunoglobulin heavy chain gene is rearranged such that each mature B-cell and plasma cell has a unique rearranged heavy chain gene profile. This process is vital to the function of B-cells in normal immune function ...
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Copy-number variation



Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.
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