Granska/Öppna
... protecting the fetus from exposure to xenobiotics during pregnancy. The multidrug resistanceassociated protein 1 (MRP1) is a relatively less studied transporter protein in the human placenta. The aim of this study series was to study the role of placental transporters, apical P-gp and basal MRP1, us ...
... protecting the fetus from exposure to xenobiotics during pregnancy. The multidrug resistanceassociated protein 1 (MRP1) is a relatively less studied transporter protein in the human placenta. The aim of this study series was to study the role of placental transporters, apical P-gp and basal MRP1, us ...
ACCELERATED INDUCTION OF ETORPHINE IMMOBILIZATION IN BLUE WILDEBEEST BY THE ADDITION OF HYALURONIDASE
... Another method commonly used to facilitate faster immobilization is the addition of hyaluronidase to drug combinations. The added hyaluronidase is believed to reduce the viscosity of the interstitial barrier between cells thereby aiding with the diffusion of substances within the tissues.50,58 As a ...
... Another method commonly used to facilitate faster immobilization is the addition of hyaluronidase to drug combinations. The added hyaluronidase is believed to reduce the viscosity of the interstitial barrier between cells thereby aiding with the diffusion of substances within the tissues.50,58 As a ...
$doc.title
... initiated treatment with titration to a maximum of 900 mg/day gabapentin over 3 days. Dosages were then to be titrated in 600 to 1200 mg/day increments at 3- to 7-day intervals to target dose over 3 to 4 weeks. In Study 1, patients were continued on lower doses if not able to achieve the target dose ...
... initiated treatment with titration to a maximum of 900 mg/day gabapentin over 3 days. Dosages were then to be titrated in 600 to 1200 mg/day increments at 3- to 7-day intervals to target dose over 3 to 4 weeks. In Study 1, patients were continued on lower doses if not able to achieve the target dose ...
RM-0106.02
... established. Geriatric Use Clinical studies of vancomycin HCl for oral use did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the e ...
... established. Geriatric Use Clinical studies of vancomycin HCl for oral use did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the e ...
GYNO-DAKTARIN™ Janssen Pharma
... The concurrent use of latex condoms or diaphragms with vaginal anti-infective preparations may decrease the effectiveness of latex contraceptive agents. Therefore, GYNO-DAKTARIN products should not be used concurrently with a latex condom or latex diaphragm. Interactions with Other Medicinal Product ...
... The concurrent use of latex condoms or diaphragms with vaginal anti-infective preparations may decrease the effectiveness of latex contraceptive agents. Therefore, GYNO-DAKTARIN products should not be used concurrently with a latex condom or latex diaphragm. Interactions with Other Medicinal Product ...
S F R SAMHSA
... without producing significant signs of withdrawal (Vocci, Acri et al., 2005). Safety. The high-affinity blockade imposed by buprenorphine significantly limits the effects of subsequently administered opioid agonists or antagonists, and the “ceiling effect” appears to confer a high safety profile, a ...
... without producing significant signs of withdrawal (Vocci, Acri et al., 2005). Safety. The high-affinity blockade imposed by buprenorphine significantly limits the effects of subsequently administered opioid agonists or antagonists, and the “ceiling effect” appears to confer a high safety profile, a ...
CIPROXIN Tablets PI
... Dilution or infusion techniques-either quantitative (MIC) or breakpoint, should be used following a regularly, updated recognised and standardised method (e.g. NCCLS). Standardised susceptibility test procedures require the use of laboratory control microorganisms to control the technical aspects of ...
... Dilution or infusion techniques-either quantitative (MIC) or breakpoint, should be used following a regularly, updated recognised and standardised method (e.g. NCCLS). Standardised susceptibility test procedures require the use of laboratory control microorganisms to control the technical aspects of ...
Why Marijuana Legalization is NOT a Good Idea For Texas
... that they will become dependent on marijuana or other drugs later in life.34 When teens use marijuana, they have a much greater chance of developing addiction than adults. 1 in 11 people who try marijuana will become addicted to it. If marijuana use starts in adolescence, the chance of addiction ris ...
... that they will become dependent on marijuana or other drugs later in life.34 When teens use marijuana, they have a much greater chance of developing addiction than adults. 1 in 11 people who try marijuana will become addicted to it. If marijuana use starts in adolescence, the chance of addiction ris ...
Naturally Occurring and Related Synthetic Cannabinoids and their
... In vivo Testing of endocannabinoids produce behavioral and pharmacological actions associated with other cannabimimetic ligands. Anandamide (5a) produces antinociception, hypothermia, hypomobility, and catalepsy in the mouse tetrad model, with rapid onset of effects, but with a short duration of act ...
... In vivo Testing of endocannabinoids produce behavioral and pharmacological actions associated with other cannabimimetic ligands. Anandamide (5a) produces antinociception, hypothermia, hypomobility, and catalepsy in the mouse tetrad model, with rapid onset of effects, but with a short duration of act ...
FOOD AND DRUG ADMINISTRATION, et al
... 61 Fed. Reg. 44,619, 45,194 (1996) (footnote omitted) (emphasis added); see also id. at 45,198-99. Consistent with this statement, FDA did not identify any brands that currently make "satisfaction" claims. Moreover, a claims-based rationale would apply only to the brands bearing a given claim, and c ...
... 61 Fed. Reg. 44,619, 45,194 (1996) (footnote omitted) (emphasis added); see also id. at 45,198-99. Consistent with this statement, FDA did not identify any brands that currently make "satisfaction" claims. Moreover, a claims-based rationale would apply only to the brands bearing a given claim, and c ...
министерство здравоохранения республики беларусь
... Representative textbook of test controls «Pharmacology in questions and answers» consists of more than 100 tests with different level of complexity. Test controls are divided according to basic pharmacological groups: — neurotropic drugs; — drugs acting on different organs and systems; — drugs actin ...
... Representative textbook of test controls «Pharmacology in questions and answers» consists of more than 100 tests with different level of complexity. Test controls are divided according to basic pharmacological groups: — neurotropic drugs; — drugs acting on different organs and systems; — drugs actin ...
Traumeel Zeel Injection Booklet
... 2 Orlandini, A., Rossi, M., Setti, M., The Effectiveness of Zeel® Injection Solution and new Research Methods in Rheumatology. Biologische Medizin. Vol. 26 (4) 1997, 164-165. ...
... 2 Orlandini, A., Rossi, M., Setti, M., The Effectiveness of Zeel® Injection Solution and new Research Methods in Rheumatology. Biologische Medizin. Vol. 26 (4) 1997, 164-165. ...
A Comparison of Thermodynamic Parameters for Vinorelbine
... at all temperatures studied. According to the Wyman (1964) linkage theory, this means that more vinorelbine binds to tubulin than vinflunine under all comparable conditions. We do not find a significant difference in K1, drug binding to tubulin heterodimers, for vinorelbine and vinflunine (Tables 1 ...
... at all temperatures studied. According to the Wyman (1964) linkage theory, this means that more vinorelbine binds to tubulin than vinflunine under all comparable conditions. We do not find a significant difference in K1, drug binding to tubulin heterodimers, for vinorelbine and vinflunine (Tables 1 ...
ACHIEVING BALANCE 2013 in State Pain Policy A Progress Report Card
... (1) the medical under-treatment of pain and (2) the non-medical use of controlled substances — both of which involve the opioid analgesic class of medications. Patients with pain may receive many pharmaceutical and non-pharmaceutical treatments, depending on the diagnosis, but opioid analgesics are ...
... (1) the medical under-treatment of pain and (2) the non-medical use of controlled substances — both of which involve the opioid analgesic class of medications. Patients with pain may receive many pharmaceutical and non-pharmaceutical treatments, depending on the diagnosis, but opioid analgesics are ...
Epclusa - Gilead
... (HARVONI (ledipasvir/sofosbuvir)). Bradycardia has generally occurred within hours to days, but cases have been observed up to 2 weeks after initiating HCV treatment. Patients also taking beta blockers, or those with underlying cardiac comorbidities and/or advanced liver disease may be at increased ...
... (HARVONI (ledipasvir/sofosbuvir)). Bradycardia has generally occurred within hours to days, but cases have been observed up to 2 weeks after initiating HCV treatment. Patients also taking beta blockers, or those with underlying cardiac comorbidities and/or advanced liver disease may be at increased ...
china pharmaceutical industry
... to become the world’s largest within only ten years. OTC sales almost doubled from 2003 to 2009 to approximately $12 billion. Prescription sales grew at around 20% annually over the same period. Although Traditional Chinese Medicines (TCM) play an important role in Chinese healthcare, Western medic ...
... to become the world’s largest within only ten years. OTC sales almost doubled from 2003 to 2009 to approximately $12 billion. Prescription sales grew at around 20% annually over the same period. Although Traditional Chinese Medicines (TCM) play an important role in Chinese healthcare, Western medic ...
Application of Hepatocytes for In Vitro Uptake Studies
... Effect of hepatocyte concentration in incubation High hepatocyte concentrations in incubation decreases observed metabolic clearance for transported drugs Result: Unbound cell-to-medium ratio decreases for actively transported drugs with increasing hepatocyte concentration Lower [Drug] in hepatocyte ...
... Effect of hepatocyte concentration in incubation High hepatocyte concentrations in incubation decreases observed metabolic clearance for transported drugs Result: Unbound cell-to-medium ratio decreases for actively transported drugs with increasing hepatocyte concentration Lower [Drug] in hepatocyte ...
DOCEtaxel - Cancer Care Ontario
... No adjustment required, but caution should be exercised in elderly patients with poor performance status who are receiving docetaxel. Patients over the age of 60 years appear to have increased toxicity when docetaxel is used in combination with capecitabine, as do patients treated with docetaxel for ...
... No adjustment required, but caution should be exercised in elderly patients with poor performance status who are receiving docetaxel. Patients over the age of 60 years appear to have increased toxicity when docetaxel is used in combination with capecitabine, as do patients treated with docetaxel for ...
Drug-induced oral lichenoid reactions. A literature review
... “suggestive”, in those situations where the histopathological and clinical findings are less clear than in classical lichen planus (2). In addition, the absence of histological confirmation in most of the articles published on OLPrelated disorders makes it difficult to establish their true prevalenc ...
... “suggestive”, in those situations where the histopathological and clinical findings are less clear than in classical lichen planus (2). In addition, the absence of histological confirmation in most of the articles published on OLPrelated disorders makes it difficult to establish their true prevalenc ...
Is the Role of the Small Intestine in First
... normal volunteers (Melander et al., 1977b). However, the blood flow change is not the sole cause responsible for the increased bioavailability after a meal. For example, it is difficult to explain how a standardized breakfast could increase the bioavailability of hydralazine 2to 3-fold (Melander et ...
... normal volunteers (Melander et al., 1977b). However, the blood flow change is not the sole cause responsible for the increased bioavailability after a meal. For example, it is difficult to explain how a standardized breakfast could increase the bioavailability of hydralazine 2to 3-fold (Melander et ...
Is the Role of the Small Intestine in First
... normal volunteers (Melander et al., 1977b). However, the blood flow change is not the sole cause responsible for the increased bioavailability after a meal. For example, it is difficult to explain how a standardized breakfast could increase the bioavailability of hydralazine 2to 3-fold (Melander et ...
... normal volunteers (Melander et al., 1977b). However, the blood flow change is not the sole cause responsible for the increased bioavailability after a meal. For example, it is difficult to explain how a standardized breakfast could increase the bioavailability of hydralazine 2to 3-fold (Melander et ...
Author`s personal copy - Texas Christian University
... The present experiments were designed to determine whether the N-methyl-d-aspartate glutamate receptor (NMDAR) is involved in memory consolidation in the cSNC situation. There is a well established connection between glucocorticoids and NMDARs, although the relationship is complex. For example, gluc ...
... The present experiments were designed to determine whether the N-methyl-d-aspartate glutamate receptor (NMDAR) is involved in memory consolidation in the cSNC situation. There is a well established connection between glucocorticoids and NMDARs, although the relationship is complex. For example, gluc ...